dbPTM

YM01_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YM01_YEAST
UniProt AC	Q04461
Protein Name	Uncharacterized protein YMR111C
Gene Name	YMR111C
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	462
Subcellular Localization
Protein Description
Protein Sequence	MPAREYNYVEGFGGYGSLDDDDSDRDSERRNHDLGQRTITTSPTGVSRHAALNRYMIPGRINPLFRPTDAAQPPIVSTSTSASATEPTNRIGPGRIKETPETNFNAFLIAQLTRMEEQNANLKEEISLMKKEQELFFLENQKKLEKGFKDINKYVEDVSAMKEVFKEVVGIMTGERIRFIDHTGENVTPQEAARVGNPSTSTQAHQSQSRSTNWQEYSMHASILAGDPRIKPEPGLSDFENGEYDGNESDENATTRNLPLNNPDSVSNADDSNNQLDGTGNENDIRNRRGCVGTSYKLNRAIQNVTDAAREYFEGLPGQPSVLSLERRYGSTWRRSAKERTLFTKRMTIIKRIIDIKDDPSKYGLSLPENKISRNQAIKVVENIRLGNNTFKGHHCRLSMSQLYEYFSKKMDKLEDYSLTLKRRGKPRRIFLLEEREARLSLQQPHSIPNSSTGTPEHDQDT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
362	Acetylation	DIKDDPSKYGLSLPE HCCCCHHHCCCCCCC	49.04	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YM01_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YM01_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YM01_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YM01_YEAST	YMR111C	physical	11967834
RMR1_YEAST	RMR1	physical	18719252
YM01_YEAST	YMR111C	physical	18719252
SLX5_YEAST	SLX5	physical	18719252
SMT3_YEAST	SMT3	physical	18719252
SET2_YEAST	SET2	genetic	20959818
STB5_YEAST	STB5	genetic	20959818
RXT2_YEAST	RXT2	genetic	20959818
SAS3_YEAST	SAS3	genetic	20959818
MOT3_YEAST	MOT3	genetic	20959818
SSN3_YEAST	SSN3	genetic	20959818
AF9_YEAST	YAF9	genetic	20959818
DOA1_YEAST	DOA1	genetic	20959818
SWR1_YEAST	SWR1	genetic	20959818
CTF18_YEAST	CTF18	genetic	20959818
SEM1_YEAST	SEM1	genetic	20959818
HRB1_YEAST	HRB1	genetic	27708008
AAR2_YEAST	AAR2	genetic	27708008
TCPD_YEAST	CCT4	genetic	27708008
TCPZ_YEAST	CCT6	genetic	27708008
RPN12_YEAST	RPN12	genetic	27708008
PRS8_YEAST	RPT6	genetic	27708008
CDC12_YEAST	CDC12	genetic	27708008
MOB1_YEAST	MOB1	genetic	27708008
YJ9I_YEAST	YJR141W	genetic	27708008
PRP19_YEAST	PRP19	genetic	27708008
GEM1_YEAST	GEM1	genetic	27708008
H3_YEAST	HHT1	genetic	27708008
STE50_YEAST	STE50	genetic	27708008
GDIR_YEAST	RDI1	genetic	27708008
UME6_YEAST	UME6	genetic	27708008
SSF1_YEAST	SSF1	genetic	27708008
STB5_YEAST	STB5	genetic	27708008
SDS3_YEAST	SDS3	genetic	27708008
ESL1_YEAST	ESL1	genetic	27708008
YJY1_YEAST	YJR011C	genetic	27708008
IXR1_YEAST	IXR1	genetic	27708008
CYT2_YEAST	CYT2	genetic	27708008
UPS1_YEAST	UPS1	genetic	27708008
RL6B_YEAST	RPL6B	genetic	27708008
VPS71_YEAST	VPS71	genetic	27708008
PET8_YEAST	PET8	genetic	27708008
SIN3_YEAST	SIN3	genetic	27708008
CY1_YEAST	CYT1	genetic	27708008
PDE2_YEAST	PDE2	genetic	27708008
PMA2_YEAST	PMA2	genetic	27708008
ALDH6_YEAST	ALD6	genetic	27708008
RU2A_YEAST	LEA1	genetic	27708008
THP3_YEAST	THP3	genetic	27708008
DOCK8_HUMAN	DOCK8	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YM01_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-237 AND SER-249, ANDMASS SPECTROMETRY.	18407956 [Abstract]
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-249 AND THR-455, ANDMASS SPECTROMETRY.	17563356 [Abstract]