GEM1_YEAST - dbPTM
GEM1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GEM1_YEAST
UniProt AC P39722
Protein Name Mitochondrial Rho GTPase 1
Gene Name GEM1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 662
Subcellular Localization Mitochondrion outer membrane
Single-pass type IV membrane protein .
Protein Description Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (Probable)..
Protein Sequence MTKETIRVVICGDEGVGKSSLIVSLTKAEFIPTIQDVLPPISIPRDFSSSPTYSPKNTVLIDTSDSDLIALDHELKSADVIWLVYCDHESYDHVSLFWLPHFRSLGLNIPVILCKNKCDSISNVNANAMVVSENSDDDIDTKVEDEEFIPILMEFKEIDTCIKTSAKTQFDLNQAFYLCQRAITHPISPLFDAMVGELKPLAVMALKRIFLLSDLNQDSYLDDNEILGLQKKCFNKSIDVNELNFIKDLLLDISKHDQEYINRKLYVPGKGITKDGFLVLNKIYAERGRHETTWAILRTFHYTDSLCINDKILHPRLVVPDTSSVELSPKGYRFLVDIFLKFDIDNDGGLNNQELHRLFKCTPGLPKLWTSTNFPFSTVVNNKGCITLQGWLAQWSMTTFLNYSTTTAYLVYFGFQEDARLALQVTKPRKMRRRSGKLYRSNINDRKVFNCFVIGKPCCGKSSLLEAFLGRSFSEEYSPTIKPRIAVNSLELKGGKQYYLILQELGEQEYAILENKDKLKECDVICLTYDSSDPESFSYLVSLLDKFTHLQDLPLVFVASKADLDKQQQRCQIQPDELADELFVNHPLHISSRWLSSLNELFIKITEAALDPGKNTPGLPEETAAKDVDYRQTALIFGSTVGFVALCSFTLMKLFKSSKFSK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
50PhosphorylationIPRDFSSSPTYSPKN
CCCCCCCCCCCCCCC		21.7727214570
54PhosphorylationFSSSPTYSPKNTVLI
CCCCCCCCCCCEEEE		31.6923749301
274AcetylationVPGKGITKDGFLVLN
CCCCCCCCCCEEEEE		54.6724489116
482UbiquitinationEEYSPTIKPRIAVNS
CCCCCCCCCEEEEEE		30.6223749301
493UbiquitinationAVNSLELKGGKQYYL
EEEEEEECCCEEEEE		57.1323749301
566UbiquitinationASKADLDKQQQRCQI
EEHHHHHHHHHHHCC		58.2523749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GEM1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GEM1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GEM1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HUA2_YEASTHUA2physical
16429126
G3P2_YEASTTDH2physical
16429126
MIC60_YEASTMIC60genetic
18245340
MMR1_YEASTMMR1genetic
18245340
PHB2_YEASTPHB2genetic
18245340
TOM70_YEASTTOM70genetic
18245340
APP1_YEASTAPP1genetic
18245340
ATPA_YEASTATP1genetic
18245340
CHO2_YEASTCHO2genetic
18245340
COQ5_YEASTCOQ5genetic
18245340
CYT2_YEASTCYT2genetic
18245340
ICE2_YEASTICE2genetic
18245340
PLMT_YEASTOPI3genetic
18245340
PLP1_YEASTPLP1genetic
18245340
PP2C1_YEASTPTC1genetic
18245340
SNF1_YEASTSNF1genetic
18245340
AIM11_YEASTAIM11genetic
18245340
YHM2_YEASTYHM2genetic
18245340
MCP2_YEASTMCP2genetic
18245340
ADE_YEASTAAH1genetic
18245340
AEP1_YEASTAEP1genetic
18245340
ARO8_YEASTARO8genetic
18245340
ATP10_YEASTATP10genetic
18245340
ATP12_YEASTATP12genetic
18245340
ATP7_YEASTATP7genetic
18245340
BRE5_YEASTBRE5genetic
18245340
CCE1_YEASTCCE1genetic
18245340
COX19_YEASTCOX19genetic
18245340
EOS1_YEASTEOS1genetic
18245340
MGR3_YEASTMGR3genetic
18245340
FMP30_YEASTFMP30genetic
18245340
GCN1_YEASTGCN1genetic
18245340
IMP1_YEASTIMP1genetic
18245340
MDM38_YEASTMDM38genetic
18245340
RM03_YEASTMRPL3genetic
18245340
MSS18_YEASTMSS18genetic
18245340
MSS51_YEASTMSS51genetic
18245340
NPT1_YEASTNPT1genetic
18245340
PT122_YEASTPET122genetic
18245340
NPR3_YEASTNPR3genetic
18245340
TIM13_YEASTTIM13genetic
18245340
VTS1_YEASTVTS1genetic
18245340
GEP7_YEASTGEP7genetic
18245340
MTC3_YEASTMTC3genetic
18245340
YL422_YEASTYLR422Wgenetic
18245340
RTC6_YEASTRTC6genetic
18245340
YPT1_YEASTYPT1genetic
18245340
BUB2_YEASTBUB2genetic
19818621
MDM10_YEASTMDM10physical
21945531
MDM12_YEASTMDM12physical
21945531
MDM34_YEASTMDM34physical
21945531
MMM1_YEASTMMM1physical
21945531
FMP30_YEASTFMP30genetic
21825164
CRD1_YEASTCRD1genetic
21825164
PHB1_YEASTPHB1genetic
21825164
PHB2_YEASTPHB2genetic
21825164
PSD2_YEASTPSD2genetic
21825164
SGPL_YEASTDPL1genetic
21825164
SHE9_YEASTSHE9genetic
27708008
RIM15_YEASTRIM15genetic
27708008
RCY1_YEASTRCY1genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
RMD9L_YEASTYBR238Cgenetic
27708008
MIC12_YEASTMIC12genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
UBP5_YEASTUBP5genetic
27708008
MIC19_YEASTMIC19genetic
27708008
GEP7_YEASTGEP7genetic
27708008
PHB2_YEASTPHB2genetic
27708008
YIH7_YEASTYIL077Cgenetic
27708008
YII9_YEASTYIL089Wgenetic
27708008
XBP1_YEASTXBP1genetic
27708008
6P21_YEASTPFK26genetic
27708008
AYR1_YEASTAYR1genetic
27708008
CSM2_YEASTCSM2genetic
27708008
MLP2_YEASTMLP2genetic
27708008
BNR1_YEASTBNR1genetic
27708008
YIS7_YEASTYIR007Wgenetic
27708008
IRC8_YEASTIRC8genetic
27708008
ALY2_YEASTALY2genetic
27708008
BCK1_YEASTBCK1genetic
27708008
SET4_YEASTSET4genetic
27708008
DS1P1_YEASTLCB3genetic
27708008
RS21B_YEASTRPS21Bgenetic
27708008
RPA34_YEASTRPA34genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
KAPA_YEASTTPK1genetic
27708008
AVT1_YEASTAVT1genetic
27708008
RAD26_YEASTRAD26genetic
27708008
YJ31_YEASTYJR061Wgenetic
27708008
IME1_YEASTIME1genetic
27708008
YJ68_YEASTYJR098Cgenetic
27708008
MMR1_YEASTMMR1genetic
27708008
MCP2_YEASTMCP2genetic
27708008
PPZ1_YEASTPPZ1genetic
27708008
MGR3_YEASTMGR3genetic
27708008
APP1_YEASTAPP1genetic
27708008
TOM70_YEASTTOM70genetic
27708008
MDM38_YEASTMDM38genetic
27708008
FMP30_YEASTFMP30genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GEM1_YEAST

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Related Literatures of Post-Translational Modification

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