SET4_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SET4_YEAST
• UniProt AC: P42948
• Protein Name: SET domain-containing protein 4
• Gene Name: SET4
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 560
• Protein Description: Putative chromatin regulator..
• Protein Sequence: MTSPESLSSRHIRQGRTYTTTDKVISRSSSYSSNSSMSKDYGDHTPLSVSSAASETLPSPQYMPIRTFNTMPTAGPTPLHLFQNDRGIFNHHSSSGSSKTASTNKRGIAAAVALATAATIPFPLKKQNQDDNSKVSVTHNESSKENKITPSMRAEDNKPKNGCICGSSDSKDELFIQCNKCKTWQHKLCYAFKKSDPIKRDFVCKRCDSDTKVQVNQVKPMIFPRKMGDERLFQFSSIVTTSASNTNQHQQSVNNIEEQPKKRQLHYTAPTTENSNSIRKKLRQEKLVVSSHFLKPLLNEVSSSNDTEFKAITISEYKDKYVKMFIDNHYDDDWVVCSNWESSRSADIEVRKSSNERDFGVFAADSCVKGELIQEYLGKIDFQKNYQTDPNNDYRLMGTTKPKVLFHPHWPLYIDSRETGGLTRYIRRSCEPNVELVTVRPLDEKPRGDNDCRVKFVLRAIRDIRKGEEISVEWQWDLRNPIWEIINASKDLDSLPDPDKFWLMGSIKTILTNCDCACGYLGHNCPITKIKNFSEEFMRNTKESLSNKSYFNTIMHNCKP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MTSPESLSSR -----CCCHHHHHHH	25.93	30377154
32	Phosphorylation	ISRSSSYSSNSSMSK HCCCCCCCCCCCCCC	25.62	27017623
33	Phosphorylation	SRSSSYSSNSSMSKD CCCCCCCCCCCCCCC	32.28	27017623
35	Phosphorylation	SSSYSSNSSMSKDYG CCCCCCCCCCCCCCC	29.39	27017623
36	Phosphorylation	SSYSSNSSMSKDYGD CCCCCCCCCCCCCCC	31.18	27017623
38	Phosphorylation	YSSNSSMSKDYGDHT CCCCCCCCCCCCCCC	25.07	27017623
133	Phosphorylation	KQNQDDNSKVSVTHN CCCCCCCCCEEEECC	41.24	30377154
136	Phosphorylation	QDDNSKVSVTHNESS CCCCCCEEEECCHHH	25.65	30377154

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SET4_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SET4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SET4_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
T2FB_YEAST	TFG2	genetic	17314980
RPN4_YEAST	RPN4	genetic	19547744
ERG3_YEAST	ERG3	genetic	20093466
PRP9_YEAST	PRP9	genetic	27708008
RRP1_YEAST	RRP1	genetic	27708008
SWI5_YEAST	SWI5	genetic	27708008
MTH1_YEAST	MTH1	genetic	27708008
VMA21_YEAST	VMA21	genetic	27708008
IPYR_YEAST	IPP1	genetic	27708008
ORC2_YEAST	ORC2	genetic	27708008
MCM7_YEAST	MCM7	genetic	27708008
RPB1_YEAST	RPO21	genetic	27708008
RPN5_YEAST	RPN5	genetic	27708008
FCF1_YEAST	FCF1	genetic	27708008
SP110_YEAST	SPC110	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
SWC4_YEAST	SWC4	genetic	27708008
SMD1_YEAST	SMD1	genetic	27708008
CBF3A_YEAST	CBF2	genetic	27708008
SDA1_YEAST	SDA1	genetic	27708008
MPPA_YEAST	MAS2	genetic	27708008
RRP4_YEAST	RRP4	genetic	27708008
CDC12_YEAST	CDC12	genetic	27708008
SHQ1_YEAST	SHQ1	genetic	27708008
NOC3_YEAST	NOC3	genetic	27708008
TIM14_YEAST	PAM18	genetic	27708008
RSC58_YEAST	RSC58	genetic	27708008
NEP1_YEAST	EMG1	genetic	27708008
SEC13_YEAST	SEC13	genetic	27708008
MCM5_YEAST	MCM5	genetic	27708008
CDC3_YEAST	CDC3	genetic	27708008
PRP2_YEAST	PRP2	genetic	27708008
CH10_YEAST	HSP10	genetic	27708008
NSL1_YEAST	NSL1	genetic	27708008
ORC4_YEAST	ORC4	genetic	27708008
H4_YEAST	HHF1	genetic	27708008
RTR2_YEAST	RTR2	genetic	27708008
INO2_YEAST	INO2	genetic	27708008
ARO1_YEAST	ARO1	genetic	27708008
YPR1_YEAST	YPR1	genetic	27708008
DIT1_YEAST	DIT1	genetic	27708008
ERG3_YEAST	ERG3	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.