FCF1_YEAST - dbPTM
FCF1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FCF1_YEAST
UniProt AC Q05498
Protein Name rRNA-processing protein FCF1
Gene Name FCF1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 189
Subcellular Localization Nucleus, nucleolus .
Protein Description Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites..
Protein Sequence MGKAKKTRKFGLVKRTLNTKKDQRLKKNQENIKTKEDPELTRNIPQVSSALFFQYNQAIKPPYQVLIDTNFINFSIQKKVDIVRGMMDCLLAKCNPLITDCVMAELEKLGPKYRIALKLARDPRIKRLSCSHKGTYADDCLVHRVLQHKCYIVATNDAGLKQRIRKIPGIPLMSVGGHAYVIEKLPDVF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
161UbiquitinationATNDAGLKQRIRKIP
EECCHHHHHHHHCCC
36.2923749301
166UbiquitinationGLKQRIRKIPGIPLM
HHHHHHHCCCCCCEE
51.3822817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FCF1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FCF1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FCF1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ATC2_YEASTPMC1physical
11805837
QCR1_YEASTCOR1physical
11805837
RL4A_YEASTRPL4Agenetic
27708008
ECM8_YEASTECM8genetic
27708008
SPO23_YEASTSPO23genetic
27708008
YCU1_YEASTYCR051Wgenetic
27708008
PAT1_YEASTPAT1genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
PUT2_YEASTPUT2genetic
27708008
SDS3_YEASTSDS3genetic
27708008
LSM1_YEASTLSM1genetic
27708008
DENR_YEASTTMA22genetic
27708008
YPT6_YEASTYPT6genetic
27708008
SRR1L_YEASTBER1genetic
27708008
CDC73_YEASTCDC73genetic
27708008
SIP5_YEASTSIP5genetic
27708008
GYP1_YEASTGYP1genetic
27708008
VPS17_YEASTVPS17genetic
27708008
VTS1_YEASTVTS1genetic
27708008
CDC24_YEASTCDC24genetic
27708008
AAR2_YEASTAAR2genetic
27708008
ORC2_YEASTORC2genetic
27708008
RPB1_YEASTRPO21genetic
27708008
LCB2_YEASTLCB2genetic
27708008
ACT_YEASTACT1genetic
27708008
RSC8_YEASTRSC8genetic
27708008
STT3_YEASTSTT3genetic
27708008
COPB2_YEASTSEC27genetic
27708008
SPC97_YEASTSPC97genetic
27708008
PRI1_YEASTPRI1genetic
27708008
RSC4_YEASTRSC4genetic
27708008
MED14_YEASTRGR1genetic
27708008
UTP13_YEASTUTP13genetic
27708008
ARP9_YEASTARP9genetic
27708008
HAS1_YEASTHAS1genetic
27708008
LST8_YEASTLST8genetic
27708008
XRN2_YEASTRAT1genetic
27708008
CLP1_YEASTCLP1genetic
27708008
ORC4_YEASTORC4genetic
27708008
SWC3_YEASTSWC3genetic
27708008
ECM15_YEASTECM15genetic
27708008
SHE1_YEASTSHE1genetic
27708008
PIN4_YEASTPIN4genetic
27708008
AIM4_YEASTAIM4genetic
27708008
SWC5_YEASTSWC5genetic
27708008
DPH7_YEASTRRT2genetic
27708008
TXTP_YEASTCTP1genetic
27708008
BIK1_YEASTBIK1genetic
27708008
ATG15_YEASTATG15genetic
27708008
NHP10_YEASTNHP10genetic
27708008
NRP1_YEASTNRP1genetic
27708008
FADH_YEASTSFA1genetic
27708008
NOP6_YEASTNOP6genetic
27708008
PAA1_YEASTPAA1genetic
27708008
RRP8_YEASTRRP8genetic
27708008
BMH2_YEASTBMH2genetic
27708008
IES5_YEASTIES5genetic
27708008
YEW0_YEASTCOM2genetic
27708008
PEA2_YEASTPEA2genetic
27708008
GCN20_YEASTGCN20genetic
27708008
PALF_YEASTRIM8genetic
27708008
GUP1_YEASTGUP1genetic
27708008
MED5_YEASTNUT1genetic
27708008
CTU1_YEASTNCS6genetic
27708008
HXKB_YEASTHXK2genetic
27708008
YG1I_YEASTYGR026Wgenetic
27708008
PEF1_YEASTPEF1genetic
27708008
YG2G_YEASTYGR079Wgenetic
27708008
INM1_YEASTINM1genetic
27708008
LRP1_YEASTLRP1genetic
27708008
SOL3_YEASTSOL3genetic
27708008
YJ24_YEASTKCH1genetic
27708008
YKC3_YEASTYKL023Wgenetic
27708008
IXR1_YEASTIXR1genetic
27708008
ZRT3_YEASTZRT3genetic
27708008
SAC1_YEASTSAC1genetic
27708008
RL1D1_YEASTUTP30genetic
27708008
HBS1_YEASTHBS1genetic
27708008
UBI4P_YEASTUBI4genetic
27708008
CMS1_YEASTCMS1genetic
27708008
FRE8_YEASTFRE8genetic
27708008
GLYC_YEASTSHM2genetic
27708008
SIC1_YEASTSIC1genetic
27708008
ARP6_YEASTARP6genetic
27708008
ECM38_YEASTECM38genetic
27708008
DCR2_YEASTDCR2genetic
27708008
VIP1_YEASTVIP1genetic
27708008
GSF2_YEASTGSF2genetic
27708008
RS3A2_YEASTRPS1Bgenetic
27708008
CAC2_YEASTCAC2genetic
27708008
CSI1_YEASTCSI1genetic
27708008
DOM34_YEASTDOM34genetic
27708008
MKT1_YEASTMKT1genetic
27708008
CTU2_YEASTNCS2genetic
27708008
EAF7_YEASTEAF7genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
RRP6_YEASTRRP6genetic
27708008
WHI5_YEASTWHI5genetic
27708008
MSC6_YEASTMSC6genetic
27708008
HAP5_YEASTHAP5genetic
27708008
EF1G1_YEASTCAM1genetic
27708008
SUR1_YEASTSUR1genetic
27708008
MMS1_YEASTMMS1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FCF1_YEAST

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Related Literatures of Post-Translational Modification

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