| UniProt ID | PEF1_YEAST | |
|---|---|---|
| UniProt AC | P53238 | |
| Protein Name | Peflin | |
| Gene Name | PEF1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 335 | |
| Subcellular Localization | Cytoplasm . Nucleus . Bud tip . Bud neck . Accumulates at the site of bud emergence in G1 cells. In small budded G1 cells, localizes asymmetrically on the tip of the daughter cell and in the nucleus. At a later stage of the G1 phase, is found at the | |
| Protein Description | Calcium-binding protein that is required for polar bud growth and cell wall abscission. Can also bind zinc ions.. | |
| Protein Sequence | MCAKKLKYAAGDDFVRYATPKEAMEETRREFEKEKQRQQQIKVTQAQTPNTRVHSAPIPLQTQYNKNRAENGHHSYGSPQSYSPRHTKTPVDPRYNVIAQKPAGRPIPPAPTHYNNLNTSAQRIASSPPPLIHNQAVPAQLLKKVAPASFDSREDVRDMQVATQLFHNHDVKGKNRLTAEELQNLLQNDDNSHFCISSVDALINLFGASRFGTVNQAEFIALYKRVKSWRKVYVDNDINGSLTISVSEFHNSLQELGYLIPFEVSEKTFDQYAEFINRNGTGKELKFDKFVEALVWLMRLTKLFRKFDTNQEGIATIQYKDFIDATLYLGRFLPH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Acetylation | -MCAKKLKYAAGDDF -CCCCCHHHHHCCCC | 41.54 | 25381059 | |
| 48 | Phosphorylation | IKVTQAQTPNTRVHS HHEEECCCCCCCCEE | 22.86 | 21440633 | |
| 51 | Phosphorylation | TQAQTPNTRVHSAPI EECCCCCCCCEECCC | 34.96 | 21440633 | |
| 55 | Phosphorylation | TPNTRVHSAPIPLQT CCCCCCEECCCCCCC | 32.65 | 20377248 | |
| 78 | Phosphorylation | NGHHSYGSPQSYSPR CCCCCCCCCCCCCCC | 16.13 | 28889911 | |
| 81 | Phosphorylation | HSYGSPQSYSPRHTK CCCCCCCCCCCCCCC | 30.84 | 28889911 | |
| 83 | Phosphorylation | YGSPQSYSPRHTKTP CCCCCCCCCCCCCCC | 22.24 | 28889911 | |
| 126 | Phosphorylation | TSAQRIASSPPPLIH HHHHHHHCCCCCCCC | 40.79 | 22369663 | |
| 127 | Phosphorylation | SAQRIASSPPPLIHN HHHHHHCCCCCCCCC | 32.19 | 22369663 | |
| 149 | Phosphorylation | LKKVAPASFDSREDV HHHHCCCCCCCHHHH | 28.64 | 30377154 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PEF1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PEF1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PEF1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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