| UniProt ID | VPS51_YEAST | |
|---|---|---|
| UniProt AC | P36116 | |
| Protein Name | Vacuolar protein sorting-associated protein 51 | |
| Gene Name | VPS51 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 164 | |
| Subcellular Localization |
Golgi apparatus, trans-Golgi network membrane Peripheral membrane protein . Endosome membrane Peripheral membrane protein . |
|
| Protein Description | Involved in retrograde transport from early and late endosomes to late Golgi. Links the Golgi-associated retrograde protein (GARP) complex to the t-SNARE TLG1, leading to the fusion between the endosomal vesicles with the late Golgi. May also be indirectly involved in apical bud growth.. | |
| Protein Sequence | MAEQISHKKSLRVSSLNKDRRLLLREFYNLENEPNKGRQEARIGEKASEAHSGEEQVTDVNIDTEANTEKPVKDDELSATEEDLKEGSEDAEEEIKNLPFKRLVQIHNKLLGKETETNNSIKNTIYENYYDLIKVNDLLKEITNANEDQINKLKQTVESLIKEL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MAEQISHKK ------CCCCCCCCC | 19.87 | 22814378 | |
| 8 | Acetylation | MAEQISHKKSLRVSS CCCCCCCCCCCCHHH | 36.95 | 25381059 | |
| 14 | Phosphorylation | HKKSLRVSSLNKDRR CCCCCCHHHCCHHHH | 23.75 | 24961812 | |
| 15 | Phosphorylation | KKSLRVSSLNKDRRL CCCCCHHHCCHHHHH | 32.86 | 21440633 | |
| 18 | Acetylation | LRVSSLNKDRRLLLR CCHHHCCHHHHHHHH | 58.88 | 25381059 | |
| 48 | Phosphorylation | ARIGEKASEAHSGEE HHHCHHHHHCCCCCC | 46.51 | 28132839 | |
| 52 | Phosphorylation | EKASEAHSGEEQVTD HHHHHCCCCCCCCCC | 55.75 | 19823750 | |
| 58 | Phosphorylation | HSGEEQVTDVNIDTE CCCCCCCCCCCCCCC | 33.64 | 19823750 | |
| 64 | Phosphorylation | VTDVNIDTEANTEKP CCCCCCCCCCCCCCC | 32.95 | 21551504 | |
| 68 | Phosphorylation | NIDTEANTEKPVKDD CCCCCCCCCCCCCCC | 53.05 | 28132839 | |
| 78 | Phosphorylation | PVKDDELSATEEDLK CCCCCCCCCCHHHHH | 30.97 | 19823750 | |
| 80 | Phosphorylation | KDDELSATEEDLKEG CCCCCCCCHHHHHHC | 36.21 | 22890988 | |
| 88 | Phosphorylation | EEDLKEGSEDAEEEI HHHHHHCCCCHHHHH | 33.13 | 28889911 | |
| 109 | Acetylation | RLVQIHNKLLGKETE HHHHHHHHHCCCCCC | 30.81 | 24489116 | |
| 113 | Ubiquitination | IHNKLLGKETETNNS HHHHHCCCCCCCCCH | 62.52 | 23749301 | |
| 140 | Ubiquitination | IKVNDLLKEITNANE HHHHHHHHHHHCCCH | 55.13 | 23749301 | |
| 143 | Phosphorylation | NDLLKEITNANEDQI HHHHHHHHCCCHHHH | 29.39 | 21440633 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VPS51_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VPS51_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VPS51_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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