SLP1_YEAST - dbPTM
SLP1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SLP1_YEAST
UniProt AC Q12232
Protein Name Uncharacterized protein SLP1 {ECO:0000305}
Gene Name SLP1 {ECO:0000303|PubMed:16923827}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 587
Subcellular Localization Endoplasmic reticulum membrane
Single-pass type I membrane protein .
Protein Description May be involved in membrane protein folding. [PubMed: 19325107 Required for localization of MPS3 to the nuclear envelope]
Protein Sequence MANRLLIYGLILWVSIIGSFALDRNKTAQNAKIGLHDTTVITTGSTTNVQKEHSSPLSTGSLRTHDFRQASKVDIRQADIRENGERKEQDALTQPATPRNPGDSSNSFLSFDEWKKVKSKEHSSGPERHLSRVREPVDPSCYKEKECIGEELEIDLGFLTNKNEWSEREENQKGFNEEKDIEKVYKKKFNYASLDCAATIVKSNPEAIGATSTLIESKDKYLLNPCSAPQQFIVIELCEDILVEEIEIANYEFFSSTFKRFRVSVSDRIPMVKNEWTILGEFEARNSRELQKFQIHNPQIWASYLKIEILSHYEDEFYCPISLIKVYGKSMMDEFKIDQLKAQEDKEQSIGTNNINNLNEQNIQDRCNNIETRLETPNTSNLSDLAGALSCTSKLIPLKFDEFFKVLNASFCPSKQMISSSSSSAVPVIPEESIFKNIMKRLSQLETNSSLTVSYIEEQSKLLSKSFEQLEMAHEAKFSHLVTIFNETMMSNLDLLNNFANQLKDQSLRILEEQKLENDKFTNRHLLHLERLEKEVSFQRRIVYASFFAFVGLISYLLITRELYFEDFEESKNGAIEKADIVQQAIR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
25N-linked_GlycosylationGSFALDRNKTAQNAK
HHHHHCCCCCCCCCC
45.77-
378N-linked_GlycosylationETRLETPNTSNLSDL
HHHCCCCCCCCHHHH
64.66-
381N-linked_GlycosylationLETPNTSNLSDLAGA
CCCCCCCCHHHHHHH
41.34-
408N-linked_GlycosylationDEFFKVLNASFCPSK
HHHHHHHCHHCCCCH
36.20-
448N-linked_GlycosylationRLSQLETNSSLTVSY
HHHHHCCCCCCCHHH
21.89-
486N-linked_GlycosylationSHLVTIFNETMMSNL
HHHHHHCHHHHHHCH
39.72-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SLP1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SLP1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SLP1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BRE5_YEASTBRE5genetic
19325107
ERV14_YEASTERV14genetic
19325107
GLO3_YEASTGLO3genetic
19325107
HLJ1_YEASTHLJ1genetic
19325107
HRD1_YEASTHRD1genetic
19325107
ICE2_YEASTICE2genetic
19325107
PHO80_YEASTPHO80genetic
19325107
SEC66_YEASTSEC66genetic
19325107
SPT4_YEASTSPT4genetic
19325107
UBC7_YEASTUBC7genetic
19325107
VPS51_YEASTVPS51genetic
19325107
TAPT1_YEASTEMP65genetic
19325107
BUG1_YEASTBUG1genetic
19325107
CALX_YEASTCNE1genetic
19325107
ALG10_YEASTDIE2genetic
19325107
FAT1_YEASTFAT1genetic
19325107
GCR2_YEASTGCR2genetic
19325107
H2AZ_YEASTHTZ1genetic
19325107
MDY2_YEASTMDY2genetic
19325107
OST5_YEASTOST5genetic
19325107
SUM1_YEASTSUM1genetic
19325107
SWC5_YEASTSWC5genetic
19325107
VPS72_YEASTVPS72genetic
19325107
YHN8_YEASTYHR078Wgenetic
19325107
GET4_YEASTGET4genetic
19325107
SWC3_YEASTSWC3genetic
19325107
SSH1_YEASTSSH1genetic
19325107
CALX_YEASTCNE1genetic
21987634
VATB_YEASTVMA2genetic
21987634
ERD1_YEASTERD1genetic
21987634
OSTB_YEASTWBP1genetic
21987634
HAC1_YEASTHAC1genetic
21987634
IRE1_YEASTIRE1genetic
21987634
BIG1_YEASTBIG1genetic
21987634
APQ12_YEASTAPQ12genetic
21987634
VPH2_YEASTVPH2genetic
21987634
OST3_YEASTOST3genetic
21987634
AIM44_YEASTAIM44genetic
21987634
VATL2_YEASTVMA11genetic
21987634
TAPT1_YEASTEMP65physical
23275891
GPR1_YEASTGPR1genetic
27708008
ERD1_YEASTERD1genetic
27708008
MSH4_YEASTMSH4genetic
27708008
GET1_YEASTGET1genetic
27708008
YHK5_YEASTYHR045Wgenetic
27708008
VPS53_YEASTVPS53genetic
27708008
PRY2_YEASTPRY2genetic
27708008
RSSA2_YEASTRPS0Bgenetic
27708008
YL413_YEASTINA1genetic
27708008
UBX2_YEASTUBX2genetic
27708008
NU188_YEASTNUP188genetic
27708008
SPO1_YEASTSPO1genetic
27708008
THI21_YEASTTHI21genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SLP1_YEAST

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Related Literatures of Post-Translational Modification

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