MSH4_YEAST - dbPTM
MSH4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MSH4_YEAST
UniProt AC P40965
Protein Name MutS protein homolog 4
Gene Name MSH4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 878
Subcellular Localization
Protein Description Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis..
Protein Sequence MSESNLSSFISTNYFNLRSAANSSNSISKPSTKKSIRNQKSPTNISSWALKKKTLQIAETTWENNEKDSTHSHYLMTGSMASRTATSLSRYSTNASLLGPSIDCVLCCIYEVPRDISTRIGLCIINCNTGQMYLSDFMDSQIYIRVVHKLQIYQPTEILIPSSSLAPTVSKLATMIKFNVAETVKIEEGSRKCFNSQDGLAAITKYLMDDTKKDLKIEEIIDKTFALCAASAAISYMEEIISKSSRNLNAFRKLRIQFEGTENTMLIDSKTVRGLELVENKLDKNGISLWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEELKANDDLLQKLRLEMKSLPDLDKLFSRLLCINHSAIKPDQRINYVLLLKETLQSVKSLKDALNDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVWASSAIQLLNQRSYAVKSDSNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIKRQEFTDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEILLLSEETVDELLDKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIRDSRHPLLEKVLKNFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARVCNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLLRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVLLNDNSVKMNYQLTQKSVAIENSGIRVVKKIFNPDIIAEAYNIHSLLKIAKARTENEDSNGVVDQKTINQMKRIHNLVAILKECAGNEKEPLTLGKLKEINSDFIENFEE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
69PhosphorylationWENNEKDSTHSHYLM
ECCCCCCCCCCEEEC		38.8028889911
70PhosphorylationENNEKDSTHSHYLMT
CCCCCCCCCCEEECH		37.2228889911
72PhosphorylationNEKDSTHSHYLMTGS
CCCCCCCCEEECHHC		17.5728889911
74PhosphorylationKDSTHSHYLMTGSMA
CCCCCCEEECHHCHH		10.9428889911
448PhosphorylationSYAVKSDSNGLLDVS
CCEECCCCCCCHHHH		39.6328889911
589PhosphorylationYNLKENNYTIPIFTN
EECCCCCEEEEEEEC		20.0228889911
590PhosphorylationNLKENNYTIPIFTNN
ECCCCCEEEEEEECC		23.5428889911
595PhosphorylationNYTIPIFTNNLLIRD
CEEEEEEECCEEECC		24.7428889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MSH4_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MSH4_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MSH4_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZIP2_YEASTZIP2physical
11454751
MSH4_YEASTMSH4physical
9374523
MSH5_YEASTMSH5physical
9374523
PCNA_YEASTPOL30genetic
17314980
MSH5_YEASTMSH5physical
11283351
TEL2_YEASTTEL2physical
18467557
SRS2_YEASTSRS2genetic
21459050
NDT80_YEASTNDT80genetic
22500736
RS27B_YEASTRPS27Bgenetic
27708008
ELO1_YEASTELO1genetic
27708008
YRA2_YEASTYRA2genetic
27708008
GAP1_YEASTGAP1genetic
27708008
RTG3_YEASTRTG3genetic
27708008
GPR1_YEASTGPR1genetic
27708008
SAP1_YEASTSAP1genetic
27708008
TMN3_YEASTTMN3genetic
27708008
RS26B_YEASTRPS26Bgenetic
27708008
RAD4_YEASTRAD4genetic
27708008
AGA2_YEASTAGA2genetic
27708008
SGF73_YEASTSGF73genetic
27708008
MRM2_YEASTMRM2genetic
27708008
HXKB_YEASTHXK2genetic
27708008
PFD3_YEASTPAC10genetic
27708008
ASK10_YEASTASK10genetic
27708008
RIM4_YEASTRIM4genetic
27708008
NAM8_YEASTNAM8genetic
27708008
GGA2_YEASTGGA2genetic
27708008
YHR2_YEASTYHR112Cgenetic
27708008
SKN7_YEASTSKN7genetic
27708008
IRC8_YEASTIRC8genetic
27708008
YJ24_YEASTKCH1genetic
27708008
JSN1_YEASTJSN1genetic
27708008
IME1_YEASTIME1genetic
27708008
RL43A_YEASTRPL43Bgenetic
27708008
RL43B_YEASTRPL43Bgenetic
27708008
MAOM_YEASTMAE1genetic
27708008
LST4_YEASTLST4genetic
27708008
DCOR_YEASTSPE1genetic
27708008
BCH2_YEASTBCH2genetic
27708008
YK21_YEASTYKR041Wgenetic
27708008
PPR1_YEASTPPR1genetic
27708008
SUR7_YEASTSUR7genetic
27708008
MLH2_YEASTMLH2genetic
28051769
HFM1_YEASTHFM1genetic
28051769
SGS1_YEASTSGS1genetic
25329811
SNT1_YEASTSNT1genetic
29674565
STN1_YEASTSTN1genetic
29674565
TFB1_YEASTTFB1genetic
29674565
KEX1_YEASTKEX1genetic
29674565
SET3_YEASTSET3genetic
29674565
NKP2_YEASTNKP2genetic
29674565
ATP18_YEASTATP18genetic
29674565
TIM23_YEASTTIM23genetic
29674565
VPS5_YEASTVPS5genetic
29674565
DYR_YEASTDFR1genetic
29674565
LPP1_YEASTLPP1genetic
29674565
GSH1_YEASTGSH1genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MSH4_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory