dbPTM

YK21_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YK21_YEAST
UniProt AC	P36134
Protein Name	Uncharacterized protein YKR041W
Gene Name	YKR041W
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	250
Subcellular Localization
Protein Description
Protein Sequence	MSDDDYMNSDDDNDAEKRYVRPIFVRKRRREEDYVATSKDNIHHHPCDWSAKPSQRQNENEQKSTIRLVPVAMNTPKCQEKKKKRKGVGTTSHEATLFEYGESIAGYKCVTTESERDRLKRSHESESSSESEVDVFAFDQAKGISSKVEAEERYARAVRQYWRMTKDEPATLPLPGTPTLAAVSLDMIDDKSVEQFYTMSSALMDANRLDLIRRDRIRWHPDKHRYHKSKVTKLFQAINGLWEQEKTEKR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
17	Ubiquitination	DDDNDAEKRYVRPIF CCCCHHHHHHCCEEE	51.23	12872131

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YK21_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YK21_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YK21_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ASK10_YEAST	ASK10	genetic	27708008
PP2C3_YEAST	PTC3	genetic	27708008
SGF29_YEAST	SGF29	genetic	27708008
RV161_YEAST	RVS161	genetic	27708008
RIM1_YEAST	RIM1	genetic	27708008
BUD31_YEAST	BUD31	genetic	27708008
CRD1_YEAST	CRD1	genetic	27708008
OST4_YEAST	OST4	genetic	27708008
AAD4_YEAST	AAD4	genetic	27708008
TPS2_YEAST	TPS2	genetic	27708008
GNTK_YEAST	YDR248C	genetic	27708008
BCS1_YEAST	BCS1	genetic	27708008
GEP7_YEAST	GEP7	genetic	27708008
AAKG_YEAST	SNF4	genetic	27708008
DSD1_YEAST	DSD1	genetic	27708008
DBF2_YEAST	DBF2	genetic	27708008
TBP7_YEAST	YTA7	genetic	27708008
NPR3_YEAST	NPR3	genetic	27708008
LSM1_YEAST	LSM1	genetic	27708008
UBI4P_YEAST	UBI4	genetic	27708008
RCF1_YEAST	RCF1	genetic	27708008
GAL80_YEAST	GAL80	genetic	27708008
VPS9_YEAST	VPS9	genetic	27708008
MAC1_YEAST	MAC1	genetic	27708008
FAR3_YEAST	FAR3	genetic	27708008
RIM13_YEAST	RIM13	genetic	27708008
PFKA2_YEAST	PFK2	genetic	27708008
HFA1_YEAST	HFA1	genetic	27708008
MRE11_YEAST	MRE11	genetic	27708008
SCS7_YEAST	SCS7	genetic	27708008
LSM7_YEAST	LSM7	genetic	27708008
VPS27_YEAST	VPS27	genetic	27708008
ATP23_YEAST	ATP23	genetic	27708008
COQ10_YEAST	COQ10	genetic	27708008
WHI2_YEAST	WHI2	genetic	27708008
PALA_YEAST	RIM20	genetic	27708008
NCBP2_YEAST	CBC2	genetic	27708008
THP3_YEAST	THP3	genetic	27708008
BRR1_YEAST	BRR1	genetic	27708008
VPS4_YEAST	VPS4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YK21_YEAST

Related Literatures of Post-Translational Modification

Ubiquitylation
Reference	PubMed
"A proteomics approach to understanding protein ubiquitination."; Peng J., Schwartz D., Elias J.E., Thoreen C.C., Cheng D.,Marsischky G., Roelofs J., Finley D., Gygi S.P.; Nat. Biotechnol. 21:921-926(2003). Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-17, AND MASSSPECTROMETRY.	12872131 [Abstract]