| UniProt ID | MAOM_YEAST | |
|---|---|---|
| UniProt AC | P36013 | |
| Protein Name | NAD-dependent malic enzyme, mitochondrial | |
| Gene Name | MAE1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 669 | |
| Subcellular Localization | Mitochondrion matrix . | |
| Protein Description | ||
| Protein Sequence | MLRTRLSVSVAARSQLTRSLTASRTAPLRRWPIQQSRLYSSNTRSHKATTTRENTFQKPYSDEEVTKTPVGSRARKIFEAPHPHATRLTVEGAIECPLESFQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPSAVLHFEDFGVKNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGLGIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSYEANSTPAQHVYAKSDAEWAGINTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVPADLMKWTNNNALVATGSPFPPVDGYRISENNNCYSFPGIGLGAVLSRATTITDKMISAAVDQLAELSPLREGDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEQVPGGAPGETVKVPRDFDECLQWVKAQMWEPVYRPMIKVQHDPSVHTNQL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 58 | Acetylation | TRENTFQKPYSDEEV CCCCCCCCCCCCCCC | 41.55 | 24489116 | |
| 67 | Acetylation | YSDEEVTKTPVGSRA CCCCCCCCCCCCHHH | 56.88 | 24489116 | |
| 145 | Acetylation | EQLERSYKQLCYLKT HHHHHHHHHHHHHCC | 37.73 | 24489116 | |
| 151 | Acetylation | YKQLCYLKTPLAKND HHHHHHHCCCCCCCC | 22.94 | 24489116 | |
| 156 | Acetylation | YLKTPLAKNDFMTSL HHCCCCCCCCCCHHH | 65.81 | 24489116 | |
| 161 | Phosphorylation | LAKNDFMTSLRVQNK CCCCCCCHHHHHCCH | 25.30 | 22369663 | |
| 162 | Phosphorylation | AKNDFMTSLRVQNKV CCCCCCHHHHHCCHH | 11.46 | 22369663 | |
| 180 | Acetylation | ALIRRHIKELVPIIY HHHHHHHHHHCCEEE | 38.58 | 24489116 | |
| 204 | Ubiquitination | AYSHRFRKPEGVFLD HHCCCCCCCCCEEEC | 44.71 | 17644757 | |
| 298 | Acetylation | DELYMGNKFSRIRGK HHHHCCCHHHHHCCC | 38.70 | 24489116 | |
| 305 | Acetylation | KFSRIRGKQYDDFLE HHHHHCCCCHHHHHH | 35.52 | 24489116 | |
| 313 | Acetylation | QYDDFLEKFIKAVKK CHHHHHHHHHHHHHH | 55.31 | 24489116 | |
| 319 | Ubiquitination | EKFIKAVKKVYPSAV HHHHHHHHHHCCHHC | 41.19 | 17644757 | |
| 320 | Ubiquitination | KFIKAVKKVYPSAVL HHHHHHHHHCCHHCE | 40.16 | 17644757 | |
| 335 | Acetylation | HFEDFGVKNARRLLE EHHHHCHHHHHHHHH | 45.31 | 24489116 | |
| 335 | Ubiquitination | HFEDFGVKNARRLLE EHHHHCHHHHHHHHH | 45.31 | 17644757 | |
| 463 | Ubiquitination | HDVVENVKPTCLVGC HHHHHHCCCCEEEEE | 46.31 | 17644757 | |
| 487 | Ubiquitination | DVVEEMHKHNPRPII HHHHHHHHHCCCCEE | 43.71 | 17644757 | |
| 631 | Acetylation | GAPGETVKVPRDFDE CCCCCCEECCCCHHH | 54.67 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MAOM_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MAOM_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MAOM_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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