dbPTM

TVP38_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TVP38_YEAST
UniProt AC	P36164
Protein Name	Golgi apparatus membrane protein TVP38
Gene Name	TVP38
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	337
Subcellular Localization	Golgi apparatus membrane Multi-pass membrane protein .
Protein Description	Golgi membrane protein involved in vesicular trafficking and spindle migration..
Protein Sequence	MSQSYEAGNANMGQGEDDEFDGYFEDFDNDIMPNSNNGQRVGTNAGLSFNDEVNVNDDDFLDIYNMSPRERLMHNIRKNVQKLQFYFYSLRLWQQIIIVLLGIMLMIMGILLLVFHNAILHKVVVTSNDLREKMSTHFILMVLIFFVAFPPMIGYSLLSTTTGLIYGVSFEGWVTLALGSVTGSIASFVVFKTILHSRAEKLVHLNRRFEALASILQENNSYWILALLRLCPFPYSLTNGAIAGVYGISVRNFSIANIITTPKLFIYLFIGSRVKSLAESESTGSRVFDLVSIIITLLILSLTAWLLYFKTKKRYLELQNRDRQVSTDQLPELSFEV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
326	Phosphorylation	QNRDRQVSTDQLPEL HCCCCCCCCCCCCCC	20.23	22369663
327	Phosphorylation	NRDRQVSTDQLPELS CCCCCCCCCCCCCCC	28.98	22890988
334	Phosphorylation	TDQLPELSFEV---- CCCCCCCCCCC----	20.07	22890988

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TVP38_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TVP38_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TVP38_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RGP1_YEAST	RGP1	genetic	16269340
RIC1_YEAST	RIC1	genetic	16269340
DYL1_YEAST	DYN2	genetic	16269340
RBD2_YEAST	RBD2	physical	18467557
SSB1_YEAST	SSB1	physical	19536198
DPP1_YEAST	DPP1	physical	16093310
COS8_YEAST	COS8	physical	16093310
SYS1_YEAST	SYS1	physical	16093310
TRK2_YEAST	TRK2	physical	16093310
EMP46_YEAST	EMP46	physical	16093310
KTR6_YEAST	KTR6	physical	16093310
GLO3_YEAST	GLO3	genetic	23891562
RIC1_YEAST	RIC1	genetic	23891562
SEA4_YEAST	SEA4	genetic	27708008
PEX19_YEAST	PEX19	genetic	27708008
PEX13_YEAST	PEX13	genetic	27708008
TGS1_YEAST	TGS1	genetic	27708008
LCB2_YEAST	LCB2	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
RPA1_YEAST	RPA190	genetic	27708008
SLA1_YEAST	SLA1	genetic	27708008
AIM3_YEAST	AIM3	genetic	27708008
THRC_YEAST	THR4	genetic	27708008
YCY0_YEAST	YCR090C	genetic	27708008
ATG9_YEAST	ATG9	genetic	27708008
GCS1_YEAST	GCS1	genetic	27708008
CTH1_YEAST	CTH1	genetic	27708008
CAJ1_YEAST	CAJ1	genetic	27708008
SLX8_YEAST	SLX8	genetic	27708008
RAD4_YEAST	RAD4	genetic	27708008
SA155_YEAST	SAP155	genetic	27708008
PALF_YEAST	RIM8	genetic	27708008
ATC1_YEAST	PMR1	genetic	27708008
ATG1_YEAST	ATG1	genetic	27708008
YOR1_YEAST	YOR1	genetic	27708008
CRP1_YEAST	CRP1	genetic	27708008
CSK21_YEAST	CKA1	genetic	27708008
PTPA1_YEAST	RRD1	genetic	27708008
IMPX_YEAST	IMP2	genetic	27708008
RCY1_YEAST	RCY1	genetic	27708008
PTK2_YEAST	PTK2	genetic	27708008
DOHH_YEAST	LIA1	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
DHOM_YEAST	HOM6	genetic	27708008
BPT1_YEAST	BPT1	genetic	27708008
ERG3_YEAST	ERG3	genetic	27708008
RAX2_YEAST	RAX2	genetic	27708008
TOP3_YEAST	TOP3	genetic	27708008
VPS9_YEAST	VPS9	genetic	27708008
UBC7_YEAST	UBC7	genetic	27708008
CAT8_YEAST	CAT8	genetic	27708008
HDA1_YEAST	HDA1	genetic	27708008
CYB5_YEAST	CYB5	genetic	27708008
MNT4_YEAST	MNT4	genetic	27708008
PHO80_YEAST	PHO80	genetic	27708008
IZH2_YEAST	IZH2	genetic	27708008
LIPA_YEAST	LIP5	genetic	27708008
DGAT2_YEAST	DGA1	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
SUE1_YEAST	SUE1	genetic	27708008
VPS4_YEAST	VPS4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TVP38_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-326 AND THR-327, ANDMASS SPECTROMETRY.	18407956 [Abstract]