KTR6_YEAST - dbPTM
KTR6_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KTR6_YEAST
UniProt AC P54070
Protein Name Mannosyltransferase KTR6
Gene Name KTR6
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 446
Subcellular Localization Membrane
Single-pass type II membrane protein .
Protein Description Glycosyltransferase that transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. Required for addition of mannosylphosphate in yeast mannan. Recognizes any oligosaccharides with at least one alpha-1,2-linked mannobiose unit..
Protein Sequence MHVLLSKKIARFLLISFVFVLALMVTINHPKTKQMSEQYVTPYLPKSLQPIAKISAEEQRRIQSEQEEAELKQSLEGEAIRNATVNAIKEKIKSYGGNETTLGFMVPSYINHRGSPPKACFVSLITERDSMTQILQSIDEVQVKFNKNFAYPWVFISQGELDGMKQEMIRQAITDSMNGDPELINIKFAEIPADEWVYPEWIDENKAAESLISLANVPDGDSRAVRYQARYFAGFFWRHPVLDEFDWYWRVDPGIKLYCDIDHDLFRWMQDEGKVFGFTLSMSEAKEANEKIWDVTKKFAKDFPKFISENNFKSFITKKDSEDFNNCEFTSNFEIGNLNFYRSPAYRKFFNYIDEEGGIFYWKWSDSIIHTIGLSMLLPKDKIHFFENIGFHYDKYNNCPLNDDIWNQYNCNCDQGNDFTFRSGSCGGHYFDIMKKDKPEGWDRLP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
82N-linked_GlycosylationLEGEAIRNATVNAIK
HHHHHHHHHHHHHHH		33.57-
94PhosphorylationAIKEKIKSYGGNETT
HHHHHHHHCCCCCCC		32.2728889911
95PhosphorylationIKEKIKSYGGNETTL
HHHHHHHCCCCCCCE		24.8528889911
98N-linked_GlycosylationKIKSYGGNETTLGFM
HHHHCCCCCCCEEEE		38.79-
108PhosphorylationTLGFMVPSYINHRGS
CEEEECCHHCCCCCC		27.5128889911
109PhosphorylationLGFMVPSYINHRGSP
EEEECCHHCCCCCCC		10.3228889911
283PhosphorylationFGFTLSMSEAKEANE
EEEEEEHHHHHHHHH		30.9027017623
305AcetylationKFAKDFPKFISENNF
HHHHHCHHHHCCCCC		56.1524489116
313AcetylationFISENNFKSFITKKD
HHCCCCCHHCCCCCC		46.7224489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KTR6_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KTR6_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KTR6_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GST1_YEASTGTT1physical
18719252
MGA2_YEASTMGA2physical
18719252
KRE2_YEASTKRE2genetic
18408719
BDH1_YEASTBDH1genetic
20093466
ADY3_YEASTADY3genetic
20093466
SC6B1_YEASTSBH1genetic
20093466
YFM7_YEASTYFR057Wgenetic
20093466
COS12_YEASTCOS12genetic
20093466
KA122_YEASTKAP122genetic
20093466
TOS2_YEASTTOS2genetic
20093466
EFM1_YEASTEFM1genetic
20093466
YHC6_YEASTYHL026Cgenetic
20093466
SNF6_YEASTSNF6genetic
20093466
YHR2_YEASTYHR112Cgenetic
20093466
YJ9S_YEASTYJR154Wgenetic
20093466
APN1_YEASTAPN1genetic
20093466
CYT2_YEASTCYT2genetic
20093466
UBI4P_YEASTUBI4genetic
20093466
ATP10_YEASTATP10genetic
20093466
COX7_YEASTCOX7genetic
20093466
COQ7_YEASTCAT5genetic
20093466
PNT1_YEASTPNT1genetic
20093466
PALA_YEASTRIM20genetic
20093466
MNE1_YEASTMNE1genetic
20093466
HAP5_YEASTHAP5genetic
20093466
MED1_YEASTMED1genetic
20093466
QCR2_YEASTQCR2genetic
20093466
SPEE_YEASTSPE3genetic
21623372
HSP71_YEASTSSA1physical
22940862
RV167_YEASTRVS167genetic
23891562
VPS27_YEASTVPS27genetic
23891562
GLO3_YEASTGLO3genetic
23891562
GET3_YEASTGET3genetic
23891562
HACD_YEASTPHS1genetic
23891562
BDH1_YEASTBDH1genetic
27708008
TOS2_YEASTTOS2genetic
27708008
SNF6_YEASTSNF6genetic
27708008
EFM1_YEASTEFM1genetic
27708008
YHR2_YEASTYHR112Cgenetic
27708008
YJ9S_YEASTYJR154Wgenetic
27708008
YKC3_YEASTYKL023Wgenetic
27708008
CYT2_YEASTCYT2genetic
27708008
APN1_YEASTAPN1genetic
27708008
YKR18_YEASTYKR018Cgenetic
27708008
RS22B_YEASTRPS22Bgenetic
27708008
ATP10_YEASTATP10genetic
27708008
COX8_YEASTCOX8genetic
27708008
MSS1_YEASTMSS1genetic
27708008
RT17_YEASTMRPS17genetic
27708008
CY1_YEASTCYT1genetic
27708008
COQ7_YEASTCAT5genetic
27708008
PNT1_YEASTPNT1genetic
27708008
PALA_YEASTRIM20genetic
27708008
MNE1_YEASTMNE1genetic
27708008
HAP5_YEASTHAP5genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KTR6_YEAST

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Related Literatures of Post-Translational Modification

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