| UniProt ID | PALF_YEAST | |
|---|---|---|
| UniProt AC | P53179 | |
| Protein Name | pH-response regulator protein palF/RIM8 | |
| Gene Name | RIM8 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 542 | |
| Subcellular Localization | ||
| Protein Description | Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth.. | |
| Protein Sequence | MSLLRLWNKESRAPSKIKSHGIVGSYGNSMLAHNNVKQFRIDIDEPHRVWKPNESITGEAVIDIKRDITNVAIKLSLVCEVRVKTGNSPTSKNKRIEKTLEKSTFLYGQDYVKTAFSAKEKKPHVDKTTILNGLSKGEHRFPFRIRIPRGRGMLSSIKFERGSITYFLSCTLESLNNINGLKKPEARCEREFAVIVPLDVSRLPKPKTKTVVLQSASMVQNKKNKSTEDESSSYTQLTQKSTTSNSSSSSVNSKTSPLPNKTVTISVDIPQAGFMIGEIIPIDVKIDHYKPFYAPAGLTTTLVRICRVGGAGKDDPMETFRKDICQSISPIYINPETLQFQSRVYLKVPLDAFSTLTTVGKFFSFQYYIEVMVNLSKKNVVYTESNRIIGTPIGEQNGLGVENNINRIQRKMLRMVNPETLENDSEGYESSIFFKDMVNVEKLKRLRNVTGMSIETVIGTTRSEQQQSDASIPSQSSITAPQNSPSNLRDWLAPLNAYDSDDVPVPKYSPNDKVSVPSEDKQELEQKRLQQLESDPPPCDDY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 25 | Phosphorylation | KSHGIVGSYGNSMLA CCCCEECCCCCCCCC | 20.97 | 30377154 | |
| 85 | Phosphorylation | VCEVRVKTGNSPTSK EEEEEEECCCCCCCC | 38.44 | 21551504 | |
| 88 | Phosphorylation | VRVKTGNSPTSKNKR EEEECCCCCCCCCHH | 30.79 | 21551504 | |
| 90 | Phosphorylation | VKTGNSPTSKNKRIE EECCCCCCCCCHHHH | 52.75 | 21551504 | |
| 91 | Phosphorylation | KTGNSPTSKNKRIEK ECCCCCCCCCHHHHH | 37.30 | 21551504 | |
| 155 | Phosphorylation | PRGRGMLSSIKFERG CCCCCCCCEEEEECC | 22.56 | 21440633 | |
| 231 | Phosphorylation | NKSTEDESSSYTQLT CCCCCCCCCCCEEEE | 36.59 | 21440633 | |
| 232 | Phosphorylation | KSTEDESSSYTQLTQ CCCCCCCCCCEEEEE | 25.89 | 28889911 | |
| 233 | Phosphorylation | STEDESSSYTQLTQK CCCCCCCCCEEEEEE | 41.29 | 21440633 | |
| 234 | Phosphorylation | TEDESSSYTQLTQKS CCCCCCCCEEEEEEE | 10.64 | 27214570 | |
| 235 | Phosphorylation | EDESSSYTQLTQKST CCCCCCCEEEEEEEC | 21.03 | 30377154 | |
| 241 | Phosphorylation | YTQLTQKSTTSNSSS CEEEEEEECCCCCCC | 27.40 | 28889911 | |
| 256 | Phosphorylation | SSVNSKTSPLPNKTV CCCCCCCCCCCCCEE | 28.33 | 29734811 | |
| 290 | Acetylation | DVKIDHYKPFYAPAG EEECCCCCCCCCCCC | 25.82 | 24489116 | |
| 319 | Phosphorylation | GKDDPMETFRKDICQ CCCCHHHHHHHHHHH | 23.61 | 27017623 | |
| 463 | Phosphorylation | TVIGTTRSEQQQSDA EEEECCCCHHHHCCC | 37.35 | 27017623 | |
| 468 | Phosphorylation | TRSEQQQSDASIPSQ CCCHHHHCCCCCCCC | 30.70 | 19779198 | |
| 474 | Phosphorylation | QSDASIPSQSSITAP HCCCCCCCCCCCCCC | 40.81 | 19779198 | |
| 477 | Phosphorylation | ASIPSQSSITAPQNS CCCCCCCCCCCCCCC | 19.13 | 27017623 | |
| 484 | Phosphorylation | SITAPQNSPSNLRDW CCCCCCCCCCCHHHH | 25.18 | 28889911 | |
| 486 | Phosphorylation | TAPQNSPSNLRDWLA CCCCCCCCCHHHHHH | 48.60 | 28889911 | |
| 498 | Phosphorylation | WLAPLNAYDSDDVPV HHHCCCCCCCCCCCC | 18.20 | 28889911 | |
| 500 | Phosphorylation | APLNAYDSDDVPVPK HCCCCCCCCCCCCCC | 24.04 | 27017623 | |
| 515 | Phosphorylation | YSPNDKVSVPSEDKQ CCCCCCCCCCCHHHH | 33.77 | 27017623 | |
| 521 | Ubiquitination | VSVPSEDKQELEQKR CCCCCHHHHHHHHHH | 41.44 | 23749301 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PALF_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PALF_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PALF_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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