| UniProt ID | SNZ1_YEAST | |
|---|---|---|
| UniProt AC | Q03148 | |
| Protein Name | Pyridoxal 5'-phosphate synthase subunit SNZ1 | |
| Gene Name | SNZ1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 297 | |
| Subcellular Localization | ||
| Protein Description | Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by a SNO isoform. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.. | |
| Protein Sequence | MTGEDFKIKSGLAQMLKGGVIMDVVTPEQAKIAEKSGACAVMALESIPADMRKSGKVCRMSDPKMIKDIMNSVSIPVMAKVRIGHFVEAQIIEALEVDYIDESEVLTPADWTHHIEKDKFKVPFVCGAKDLGEALRRINEGAAMIRTKGEAGTGDVSEAVKHIRRITEEIKACQQLKSEDDIAKVAEEMRVPVSLLKDVLEKGKLPVVNFAAGGVATPADAALLMQLGCDGVFVGSGIFKSSNPVRLATAVVEATTHFDNPSKLLEVSSDLGELMGGVSIESISHASNGVRLSEIGW | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Acetylation | -MTGEDFKIKSGLAQ -CCCCCCCCHHHHHH | 62.64 | 25381059 | |
| 46 | Phosphorylation | CAVMALESIPADMRK CEEEEHHHCCHHHHH | 34.42 | 28889911 | |
| 64 | Acetylation | VCRMSDPKMIKDIMN CCCCCCHHHHHHHHH | 59.24 | 25381059 | |
| 67 | Acetylation | MSDPKMIKDIMNSVS CCCHHHHHHHHHHCC | 37.39 | 25381059 | |
| 72 | Phosphorylation | MIKDIMNSVSIPVMA HHHHHHHHCCCCEEE | 10.40 | 23607784 | |
| 74 | Phosphorylation | KDIMNSVSIPVMAKV HHHHHHCCCCEEEEE | 22.46 | 23607784 | |
| 80 | Acetylation | VSIPVMAKVRIGHFV CCCCEEEEEECCCHH | 17.60 | - | |
| 148 | Ubiquitination | GAAMIRTKGEAGTGD CCCEEEECCCCCCCC | 44.92 | 23749301 | |
| 161 | Acetylation | GDVSEAVKHIRRITE CCHHHHHHHHHHHHH | 40.12 | 24489116 | |
| 177 | Ubiquitination | IKACQQLKSEDDIAK HHHHHHCCCHHHHHH | 47.68 | 23749301 | |
| 177 | Acetylation | IKACQQLKSEDDIAK HHHHHHCCCHHHHHH | 47.68 | 25381059 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SNZ1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SNZ1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SNZ1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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