| UniProt ID | PHB2_YEAST | |
|---|---|---|
| UniProt AC | P50085 | |
| Protein Name | Prohibitin-2 | |
| Gene Name | PHB2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 310 | |
| Subcellular Localization |
Mitochondrion inner membrane Single-pass type II membrane protein Intermembrane side . |
|
| Protein Description | Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.. | |
| Protein Sequence | MNRSPGEFQRYAKAFQKQLSKVQQTGGRGQVPSPRGAFAGLGGLLLLGGGALFINNALFNVDGGHRAIVYSRIHGVSSRIFNEGTHFIFPWLDTPIIYDVRAKPRNVASLTGTKDLQMVNITCRVLSRPDVVQLPTIYRTLGQDYDERVLPSIVNEVLKAVVAQFNASQLITQREKVSRLIRENLVRRASKFNILLDDVSITYMTFSPEFTNAVEAKQIAQQDAQRAAFVVDKARQEKQGMVVRAQGEAKSAELIGEAIKKSRDYVELKRLDTARDIAKILASSPNRVILDNEALLLNTVVDARIDGRGK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 21 | Ubiquitination | AFQKQLSKVQQTGGR HHHHHHHHHHHCCCC | 53.29 | 23749301 | |
| 109 | Phosphorylation | AKPRNVASLTGTKDL CCCCCCHHCCCCCCE | 23.37 | 22890988 | |
| 111 | Phosphorylation | PRNVASLTGTKDLQM CCCCHHCCCCCCEEE | 40.07 | 22890988 | |
| 113 | Phosphorylation | NVASLTGTKDLQMVN CCHHCCCCCCEEEEE | 19.02 | 22890988 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PHB2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PHB2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PHB2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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