| UniProt ID | YP150_YEAST | |
|---|---|---|
| UniProt AC | Q12152 | |
| Protein Name | Putative serine/threonine-protein kinase YPL150W | |
| Gene Name | YPL150W | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 901 | |
| Subcellular Localization | ||
| Protein Description | Putative serine/threonine-protein kinase.. | |
| Protein Sequence | MVNPVGSSKLEQNNIKSIIGSSYNRLYSQFTSDELTEVGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQPYGSVVLDQTQKILCRQRSGGTQFKSKLERRLLKRLKQSGVDTQAIKQSILKKKCDSLSGLWLLLLAQGKKQENCKYPKRSRSVLSVKKVIESATHNDTNGISEDVLKPSLELSRAASLSKMLNKGSDFVTSMTPVSRKKSKDSAKVLNPTLSKISSQRAYSHSIAGSPRKSNNFLQKVSSFFKSKKSSNSNSNNSIHTNVSESLIASNRGAPSSGSFLKKNSGSIQKSRTDTVANPSRTESIGSLNENVAGAIVPRSANNTTLENKKTSGNEIGLKVAPELLLNEHIRIEEPRLKRFKSSISSEISQTSTGNYDSESAENSRSISFDGKVSPPPIRNRPLSEISQISNDTYISEYSTDGNNSSFKISDTIKPSYIRKGSETTSQYSASSEKMTNGYGRKFVRRDLSIVSTASSTSERSSRTDSFYDITTATPVVTTDNRRNKNNNLKESVLPRFGTQRPWTGKRTYTTSRHGKNARRSSKRGLFKITSSNTDSIIQEVSSSEEEDHNVIYSKGKGLPTPVLQTKGLIENGLNERDEEGDDEYAIHTDGEFSIKPQFSDDVIDKQNHLPSVKAVATKRSLSEGSNWSSSYLDSDNNRRRVSSLLVEDGGNPTA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MVNPVGSSKLEQNN -CCCCCCCCHHHHCC | 25.24 | 28889911 | |
| 8 | Phosphorylation | MVNPVGSSKLEQNNI CCCCCCCCHHHHCCH | 35.02 | 28889911 | |
| 22 | Phosphorylation | IKSIIGSSYNRLYSQ HHHHHHHHHHHHHHC | 22.63 | 19779198 | |
| 23 | Phosphorylation | KSIIGSSYNRLYSQF HHHHHHHHHHHHHCC | 13.14 | 19779198 | |
| 28 | Phosphorylation | SSYNRLYSQFTSDEL HHHHHHHHCCCCCHH | 24.33 | 21551504 | |
| 31 | Phosphorylation | NRLYSQFTSDELTEV HHHHHCCCCCHHHHH | 27.86 | 21551504 | |
| 32 | Phosphorylation | RLYSQFTSDELTEVG HHHHCCCCCHHHHHC | 30.31 | 21551504 | |
| 130 | Phosphorylation | LLSLRRISLLECGEL HHHHHHEEHHHHHHH | 25.70 | 27017623 | |
| 142 | Phosphorylation | GELFAQISGAVYYAH HHHHHHHHHHHHHHH | 14.49 | 27017623 | |
| 146 | Phosphorylation | AQISGAVYYAHSMHC HHHHHHHHHHHHHHH | 8.39 | 27017623 | |
| 150 | Phosphorylation | GAVYYAHSMHCVHRD HHHHHHHHHHHHCCC | 11.31 | 27017623 | |
| 186 | Phosphorylation | TRECMTKTTLETVCG CCCCCCCCHHHHHCC | 27.70 | 28889911 | |
| 187 | Phosphorylation | RECMTKTTLETVCGT CCCCCCCHHHHHCCC | 24.93 | 21440633 | |
| 190 | Phosphorylation | MTKTTLETVCGTTVY CCCCHHHHHCCCEEE | 24.98 | 21440633 | |
| 194 | Phosphorylation | TLETVCGTTVYMAPE HHHHHCCCEEEECHH | 14.15 | 27017623 | |
| 325 | Ubiquitination | RRLLKRLKQSGVDTQ HHHHHHHHHCCCCHH | 46.59 | 23749301 | |
| 371 | Phosphorylation | KYPKRSRSVLSVKKV CCCCCCCHHHHHHHH | 28.76 | 17287358 | |
| 374 | Phosphorylation | KRSRSVLSVKKVIES CCCCHHHHHHHHHHH | 29.72 | 17287358 | |
| 381 | Phosphorylation | SVKKVIESATHNDTN HHHHHHHHHCCCCCC | 27.61 | 19823750 | |
| 383 | Phosphorylation | KKVIESATHNDTNGI HHHHHHHCCCCCCCC | 30.41 | 19823750 | |
| 387 | Phosphorylation | ESATHNDTNGISEDV HHHCCCCCCCCCHHH | 40.43 | 19823750 | |
| 391 | Phosphorylation | HNDTNGISEDVLKPS CCCCCCCCHHHHHHH | 29.19 | 19823750 | |
| 398 | Phosphorylation | SEDVLKPSLELSRAA CHHHHHHHHHHHHHH | 32.65 | 20377248 | |
| 402 | Phosphorylation | LKPSLELSRAASLSK HHHHHHHHHHHHHHH | 15.53 | 20377248 | |
| 406 | Phosphorylation | LELSRAASLSKMLNK HHHHHHHHHHHHHHC | 31.99 | 21551504 | |
| 408 | Phosphorylation | LSRAASLSKMLNKGS HHHHHHHHHHHHCCC | 17.33 | 21440633 | |
| 413 | Ubiquitination | SLSKMLNKGSDFVTS HHHHHHHCCCCCCCC | 56.69 | 23749301 | |
| 422 | Phosphorylation | SDFVTSMTPVSRKKS CCCCCCCCCCCCCCC | 21.95 | 28152593 | |
| 425 | Phosphorylation | VTSMTPVSRKKSKDS CCCCCCCCCCCCCCC | 39.32 | 23749301 | |
| 439 | Phosphorylation | SAKVLNPTLSKISSQ CHHHHCHHHHHHHHC | 42.46 | 28889911 | |
| 441 | Phosphorylation | KVLNPTLSKISSQRA HHHCHHHHHHHHCCC | 30.35 | 19684113 | |
| 444 | Phosphorylation | NPTLSKISSQRAYSH CHHHHHHHHCCCHHC | 24.93 | 19684113 | |
| 445 | Phosphorylation | PTLSKISSQRAYSHS HHHHHHHHCCCHHCC | 27.45 | 28152593 | |
| 450 | Phosphorylation | ISSQRAYSHSIAGSP HHHCCCHHCCCCCCC | 15.13 | 19779198 | |
| 452 | Phosphorylation | SQRAYSHSIAGSPRK HCCCHHCCCCCCCCC | 14.27 | 19684113 | |
| 456 | Phosphorylation | YSHSIAGSPRKSNNF HHCCCCCCCCCCCCH | 16.71 | 21082442 | |
| 460 | Phosphorylation | IAGSPRKSNNFLQKV CCCCCCCCCCHHHHH | 37.98 | 28889911 | |
| 469 | Phosphorylation | NFLQKVSSFFKSKKS CHHHHHHHHHHCCCC | 37.38 | 21440633 | |
| 473 | Phosphorylation | KVSSFFKSKKSSNSN HHHHHHHCCCCCCCC | 39.91 | 28889911 | |
| 479 | Phosphorylation | KSKKSSNSNSNNSIH HCCCCCCCCCCCCEE | 43.51 | 19779198 | |
| 481 | Phosphorylation | KKSSNSNSNNSIHTN CCCCCCCCCCCEECC | 36.89 | 28889911 | |
| 484 | Phosphorylation | SNSNSNNSIHTNVSE CCCCCCCCEECCHHH | 21.72 | 28889911 | |
| 487 | Phosphorylation | NSNNSIHTNVSESLI CCCCCEECCHHHHHH | 35.33 | 21551504 | |
| 490 | Phosphorylation | NSIHTNVSESLIASN CCEECCHHHHHHHCC | 24.44 | 19779198 | |
| 492 | Phosphorylation | IHTNVSESLIASNRG EECCHHHHHHHCCCC | 19.98 | 19779198 | |
| 502 | Phosphorylation | ASNRGAPSSGSFLKK HCCCCCCCCCCCCCC | 46.96 | 22369663 | |
| 503 | Phosphorylation | SNRGAPSSGSFLKKN CCCCCCCCCCCCCCC | 37.08 | 22369663 | |
| 505 | Phosphorylation | RGAPSSGSFLKKNSG CCCCCCCCCCCCCCC | 29.38 | 22369663 | |
| 511 | Phosphorylation | GSFLKKNSGSIQKSR CCCCCCCCCCCCCCC | 42.68 | 27717283 | |
| 513 | Phosphorylation | FLKKNSGSIQKSRTD CCCCCCCCCCCCCCC | 22.97 | 27214570 | |
| 517 | Phosphorylation | NSGSIQKSRTDTVAN CCCCCCCCCCCCCCC | 24.84 | 28889911 | |
| 521 | Phosphorylation | IQKSRTDTVANPSRT CCCCCCCCCCCCCCC | 22.39 | 21440633 | |
| 526 | Phosphorylation | TDTVANPSRTESIGS CCCCCCCCCCCCCCC | 52.20 | 21440633 | |
| 528 | Phosphorylation | TVANPSRTESIGSLN CCCCCCCCCCCCCCC | 38.12 | 22369663 | |
| 530 | Phosphorylation | ANPSRTESIGSLNEN CCCCCCCCCCCCCCC | 31.47 | 22369663 | |
| 533 | Phosphorylation | SRTESIGSLNENVAG CCCCCCCCCCCCCCC | 26.76 | 22369663 | |
| 546 | Phosphorylation | AGAIVPRSANNTTLE CCEECCCCCCCCCEE | 29.31 | 27214570 | |
| 551 | Phosphorylation | PRSANNTTLENKKTS CCCCCCCCEECCCCC | 33.91 | 21551504 | |
| 558 | Phosphorylation | TLENKKTSGNEIGLK CEECCCCCCCCHHHE | 48.80 | 27214570 | |
| 598 | Phosphorylation | SSEISQTSTGNYDSE CHHHHCCCCCCCCCC | 27.04 | 28889911 | |
| 612 | Phosphorylation | ESAENSRSISFDGKV CCCCCCCEECCCCCC | 23.54 | 28889911 | |
| 614 | Phosphorylation | AENSRSISFDGKVSP CCCCCEECCCCCCCC | 20.66 | 25752575 | |
| 620 | Phosphorylation | ISFDGKVSPPPIRNR ECCCCCCCCCCCCCC | 34.86 | 28889911 | |
| 652 | Phosphorylation | STDGNNSSFKISDTI ECCCCCCCEEECCCC | 32.46 | 28889911 | |
| 672 | Phosphorylation | RKGSETTSQYSASSE CCCCCCCCCCCCCCC | 34.24 | 27017623 | |
| 674 | Phosphorylation | GSETTSQYSASSEKM CCCCCCCCCCCCCHH | 13.13 | 28889911 | |
| 675 | Phosphorylation | SETTSQYSASSEKMT CCCCCCCCCCCCHHC | 17.65 | 23749301 | |
| 677 | Phosphorylation | TTSQYSASSEKMTNG CCCCCCCCCCHHCCC | 32.84 | 27717283 | |
| 678 | Phosphorylation | TSQYSASSEKMTNGY CCCCCCCCCHHCCCC | 40.74 | 23749301 | |
| 682 | Phosphorylation | SASSEKMTNGYGRKF CCCCCHHCCCCCHHH | 36.24 | 27017623 | |
| 685 | Phosphorylation | SEKMTNGYGRKFVRR CCHHCCCCCHHHHHH | 18.81 | 27017623 | |
| 710 | Phosphorylation | TSERSSRTDSFYDIT CCCCCCCCCCCCCCC | 37.63 | 30377154 | |
| 712 | Phosphorylation | ERSSRTDSFYDITTA CCCCCCCCCCCCCCC | 25.70 | 23749301 | |
| 776 | Phosphorylation | KRGLFKITSSNTDSI CCCCEEECCCCHHHH | 27.05 | 22369663 | |
| 777 | Phosphorylation | RGLFKITSSNTDSII CCCEEECCCCHHHHH | 25.68 | 22369663 | |
| 778 | Phosphorylation | GLFKITSSNTDSIIQ CCEEECCCCHHHHHH | 34.79 | 19795423 | |
| 780 | Phosphorylation | FKITSSNTDSIIQEV EEECCCCHHHHHHHC | 32.83 | 19795423 | |
| 782 | Phosphorylation | ITSSNTDSIIQEVSS ECCCCHHHHHHHCCC | 21.39 | 19795423 | |
| 788 | Phosphorylation | DSIIQEVSSSEEEDH HHHHHHCCCCCCCCC | 27.65 | 22369663 | |
| 789 | Phosphorylation | SIIQEVSSSEEEDHN HHHHHCCCCCCCCCC | 47.12 | 22369663 | |
| 790 | Phosphorylation | IIQEVSSSEEEDHNV HHHHCCCCCCCCCCE | 41.33 | 22369663 | |
| 799 | Phosphorylation | EEDHNVIYSKGKGLP CCCCCEEEECCCCCC | 10.47 | 19795423 | |
| 800 | Phosphorylation | EDHNVIYSKGKGLPT CCCCEEEECCCCCCC | 24.65 | 19795423 | |
| 831 | Phosphorylation | DEEGDDEYAIHTDGE CCCCCCCEEEECCCC | 20.18 | 21440633 | |
| 835 | Phosphorylation | DDEYAIHTDGEFSIK CCCEEEECCCCCEEC | 39.32 | 21440633 | |
| 840 | Phosphorylation | IHTDGEFSIKPQFSD EECCCCCEECCCCCC | 25.96 | 21551504 | |
| 846 | Phosphorylation | FSIKPQFSDDVIDKQ CEECCCCCCCCCCCC | 27.88 | 27717283 | |
| 867 | Phosphorylation | KAVATKRSLSEGSNW HEEEECCCCCCCCCC | 37.49 | 22369663 | |
| 869 | Phosphorylation | VATKRSLSEGSNWSS EEECCCCCCCCCCCH | 40.95 | 22369663 | |
| 872 | Phosphorylation | KRSLSEGSNWSSSYL CCCCCCCCCCCHHCC | 30.95 | 22369663 | |
| 875 | Phosphorylation | LSEGSNWSSSYLDSD CCCCCCCCHHCCCCC | 17.41 | 22369663 | |
| 876 | Phosphorylation | SEGSNWSSSYLDSDN CCCCCCCHHCCCCCC | 18.02 | 22369663 | |
| 877 | Phosphorylation | EGSNWSSSYLDSDNN CCCCCCHHCCCCCCC | 24.97 | 23749301 | |
| 878 | Phosphorylation | GSNWSSSYLDSDNNR CCCCCHHCCCCCCCC | 19.24 | 22369663 | |
| 889 | Phosphorylation | DNNRRRVSSLLVEDG CCCCEEEHHEEEECC | 17.29 | 22369663 | |
| 890 | Phosphorylation | NNRRRVSSLLVEDGG CCCEEEHHEEEECCC | 23.90 | 22369663 | |
| 900 | Phosphorylation | VEDGGNPTA------ EECCCCCCC------ | 49.34 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of YP150_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of YP150_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of YP150_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-186; THR-190; SER-530;SER-533 AND SER-614, AND MASS SPECTROMETRY. | |
| "Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-371; SER-374 ANDSER-456, AND MASS SPECTROMETRY. | |
| "Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-533, AND MASSSPECTROMETRY. | |
