RIB2_YEAST - dbPTM
RIB2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RIB2_YEAST
UniProt AC Q12362
Protein Name Bifunctional protein RIB2
Gene Name RIB2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 591
Subcellular Localization Cytoplasm .
Protein Description Responsible for synthesis of pseudouridine from uracil-32 in cytoplasmic transfer RNAs.; Involved in riboflavin biosynthesis. Converts 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1H,3H)-pyrimidinedione 5'-phosphate..
Protein Sequence MEDSNNEASDDFNNLLNKEIESAKEVKLRKFANRNNNRNENSSKVKDASGFRLRVIQTDGHKTKKTDPDYEVTIDGPLRKIEPYFFTYKTFCKERWRDRKLVDVFVSEFRDREPSYYSKTIAEGKVYLNDEPANLDTIIRDGDLITHKVHRHEPPVTSKPIDIVFEDEDILVIDKPSSIPVHPTGRYRFNTITKMLERQLGYSVHPCNRLDKPTSGLMFLAKTPLGADRMGDQMKAREVTKEYVARVKGEFPIGIVEVDKPVRSVNPKVALNAVCEMSDENAKHAKTVFQRVSYDGQTSIVKCKPLTGRTHQIRVHLQYLGFPIANDPIYSNPDIWGPDLGRGGLQNYDDIVLKLDAIGKTNPAESWIHPHSEGEYLLGRQCEECEAEMYTDPGTNDLDLWLHAFRYESLERNSDTQKPLWSYRTKYPEWALEPHRRYMEMAVKEAGKCGPTKTAFSVGAVLVHGTQVLATGYSRELPGNTHAEQCALIKYSQLHPNCPTIVPMGTVLYTTMEPCSFRLSGNEPCCDRILATQGAIGTVFVGVMEPDTFVKNNTSLNKLESHGVNYIQIPGYEEECTIIAFKGHDNSDDKA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MEDSNNEASDD
----CCCCCCHHCHH		28.4028889911
58PhosphorylationFRLRVIQTDGHKTKK
CEEEEEECCCCCCCC		32.5928889911
63PhosphorylationIQTDGHKTKKTDPDY
EECCCCCCCCCCCCC		31.9028889911
89AcetylationEPYFFTYKTFCKERW
ECEEEEHHHHHHHHH		31.8722865919
119AcetylationREPSYYSKTIAEGKV
CCCCCCCCEEEECEE		28.0324489116
241AcetylationMKAREVTKEYVARVK
HHHHHHHHHHHHHHC		52.8325381059
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RIB2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RIB2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RIB2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PUS9_YEASTPUS9genetic
15466869
ADH3_YEASTADH3genetic
21623372
FOLE_YEASTMET7genetic
21623372
ELO3_YEASTELO3genetic
21623372
FADH_YEASTSFA1genetic
21623372
THDH_YEASTILV1genetic
21623372
CISY1_YEASTCIT1genetic
21623372
LCF1_YEASTFAA1genetic
21623372
CSG2_YEASTCSG2genetic
21623372
METX_YEASTYML082Wgenetic
21623372
IDH1_YEASTIDH1genetic
21623372
ACON2_YEASTACO2genetic
21623372
PPT2_YEASTPPT2genetic
21623372
ATP14_YEASTATP14genetic
21623372
COX6_YEASTCOX6genetic
21623372
TXTP_YEASTCTP1genetic
21623372
ATPO_YEASTATP5genetic
21623372
IDH2_YEASTIDH2genetic
21623372
COQ4_YEASTCOQ4genetic
21623372
COQ7_YEASTCAT5genetic
21623372
METC_YEASTIRC7genetic
21623372
QCR2_YEASTQCR2genetic
21623372
CTK1_YEASTCTK1genetic
27708008
RAD52_YEASTRAD52genetic
27708008
TRI1_YEASTTRI1genetic
27708008
CDC24_YEASTCDC24genetic
27708008
TAF5_YEASTTAF5genetic
27708008
DPOD_YEASTPOL3genetic
27708008
RRP1_YEASTRRP1genetic
27708008
SEC1_YEASTSEC1genetic
27708008
SCC4_YEASTSCC4genetic
27708008
TBP_YEASTSPT15genetic
27708008
COPB2_YEASTSEC27genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
CDC11_YEASTCDC11genetic
27708008
SSL1_YEASTSSL1genetic
27708008
POB3_YEASTPOB3genetic
27708008
ERO1_YEASTERO1genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
TFC8_YEASTTFC8genetic
27708008
GPI2_YEASTGPI2genetic
27708008
ARP7_YEASTARP7genetic
27708008
NCL1_YEASTNCL1genetic
27708008
OLA1_YEASTOLA1genetic
27708008
FTH1_YEASTFTH1genetic
27708008
SWC5_YEASTSWC5genetic
27708008
KCC4_YEASTKCC4genetic
27708008
GPR1_YEASTGPR1genetic
27708008
VPS41_YEASTVPS41genetic
27708008
GIS1_YEASTGIS1genetic
27708008
YHP1_YEASTYHP1genetic
27708008
ICP55_YEASTICP55genetic
27708008
PMD1_YEASTPMD1genetic
27708008
RTR1_YEASTRTR1genetic
27708008
RAD4_YEASTRAD4genetic
27708008
SGF73_YEASTSGF73genetic
27708008
GCN1_YEASTGCN1genetic
27708008
SKI8_YEASTSKI8genetic
27708008
RT102_YEASTRTT102genetic
27708008
EFM1_YEASTEFM1genetic
27708008
YHI9_YEASTYHI9genetic
27708008
ATG32_YEASTATG32genetic
27708008
NNK1_YEASTNNK1genetic
27708008
YL054_YEASTYLL054Cgenetic
27708008
TOP3_YEASTTOP3genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
GTR1_YEASTGTR1genetic
27708008
CSI1_YEASTCSI1genetic
27708008
AEP2_YEASTAEP2genetic
27708008
HRB1_YEASTHRB1genetic
27708008
KC12_YEASTYCK2genetic
27708008
RAD1_YEASTRAD1genetic
27708008
ELP3_YEASTELP3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RIB2_YEAST

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Related Literatures of Post-Translational Modification

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