dbPTM

METC_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	METC_YEAST
UniProt AC	P43623
Protein Name	Putative cystathionine beta-lyase
Gene Name	IRC7
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	340
Subcellular Localization
Protein Description
Protein Sequence	MIDRTELSKFGITTQLSVIGRNPDEQSGFVNPPLYKGSTIILKKLSDLEQRKGRFYGTAGSPTIDNLENAWTHLTGGAGTVLSASGLGSISLALLALSKAGDHILMTDSVYVPTRMLCDGLLAKFGVETDYYDPSIGKDIEKLVKPNTTVIFLESPGSGTMEVQDIPALVSVAKKHGIKTILDNTWATPLFFDAHAHGIDISVEAGTKYLGGHSDLLIGLASANEECWPLLRSTYDAMAMLPGAEDCQLALRGMRTLHLRLKEVERKALDLAAWLGNRDEVEKVLHPAFEDCPGHEYWVRDYKGSSGLFSIVLKNGFTRAGLEKMVEGMKVLQLGFSWGG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Phosphorylation	TIILKKLSDLEQRKG EEEEEECHHHHHHCC	49.37	28889911
208	N6-(pyridoxal phosphate)lysine	ISVEAGTKYLGGHSD EEEECCCCCCCCCCC	37.24	-
208	Other	ISVEAGTKYLGGHSD EEEECCCCCCCCCCC	37.24	-
306	Phosphorylation	VRDYKGSSGLFSIVL EEECCCCCCCEEEEE	48.46	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of METC_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of METC_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of METC_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PP2C3_YEAST	PTC3	genetic	27708008
PSB6_YEAST	PRE7	genetic	27708008
KPC1_YEAST	PKC1	genetic	27708008
MCM7_YEAST	MCM7	genetic	27708008
KRR1_YEAST	KRR1	genetic	27708008
SCC1_YEAST	MCD1	genetic	27708008
BIG1_YEAST	BIG1	genetic	27708008
CDC12_YEAST	CDC12	genetic	27708008
ARP3_YEAST	ARP3	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
NTR2_YEAST	NTR2	genetic	27708008
ERB1_YEAST	ERB1	genetic	27708008
PRP24_YEAST	PRP24	genetic	27708008
SEC63_YEAST	SEC63	genetic	27708008
GPI2_YEAST	GPI2	genetic	27708008
ATC3_YEAST	DRS2	genetic	27708008
ICS2_YEAST	ICS2	genetic	27708008
SHG1_YEAST	SHG1	genetic	27708008
THRC_YEAST	THR4	genetic	27708008
PP2C1_YEAST	PTC1	genetic	27708008
RPN4_YEAST	RPN4	genetic	27708008
VPS41_YEAST	VPS41	genetic	27708008
RRP8_YEAST	RRP8	genetic	27708008
ARX1_YEAST	ARX1	genetic	27708008
SAC3_YEAST	SAC3	genetic	27708008
ACL4_YEAST	YDR161W	genetic	27708008
RAD4_YEAST	RAD4	genetic	27708008
TFS2_YEAST	DST1	genetic	27708008
VAM7_YEAST	VAM7	genetic	27708008
MAL12_YEAST	MAL12	genetic	27708008
RL8A_YEAST	RPL8A	genetic	27708008
STB5_YEAST	STB5	genetic	27708008
BFA1_YEAST	BFA1	genetic	27708008
UBL1_YEAST	YUH1	genetic	27708008
YJ90_YEAST	YJR120W	genetic	27708008
MRT4_YEAST	MRT4	genetic	27708008
VPS24_YEAST	VPS24	genetic	27708008
CTK1_YEAST	CTK1	genetic	27708008
POM33_YEAST	POM33	genetic	27708008
ACE2_YEAST	ACE2	genetic	27708008
PET8_YEAST	PET8	genetic	27708008
OCA2_YEAST	OCA2	genetic	27708008
LSM7_YEAST	LSM7	genetic	27708008
BUD21_YEAST	BUD21	genetic	27708008
WHI5_YEAST	WHI5	genetic	27708008
HAP5_YEAST	HAP5	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
AIM44_YEAST	AIM44	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of METC_YEAST

Related Literatures of Post-Translational Modification