| UniProt ID | FADH_YEAST | |
|---|---|---|
| UniProt AC | P32771 | |
| Protein Name | S-(hydroxymethyl)glutathione dehydrogenase | |
| Gene Name | SFA1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 386 | |
| Subcellular Localization | ||
| Protein Description | Oxidizes long-chain alcohols and, in the presence of glutathione, is able to oxidize formaldehyde. Is responsible for yeast resistance to formaldehyde.. | |
| Protein Sequence | MSAATVGKPIKCIAAVAYDAKKPLSVEEITVDAPKAHEVRIKIEYTAVCHTDAYTLSGSDPEGLFPCVLGHEGAGIVESVGDDVITVKPGDHVIALYTAECGKCKFCTSGKTNLCGAVRATQGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEYTVVADVSVVAIDPKAPLDAACLLGCGVTTGFGAALKTANVQKGDTVAVFGCGTVGLSVIQGAKLRGASKIIAIDINNKKKQYCSQFGATDFVNPKEDLAKDQTIVEKLIEMTDGGLDFTFDCTGNTKIMRDALEACHKGWGQSIIIGVAAAGEEISTRPFQLVTGRVWKGSAFGGIKGRSEMGGLIKDYQKGALKVEEFITHRRPFKEINQAFEDLHNGDCLRTVLKSDEIK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 124 | Ubiquitination | AVRATQGKGVMPDGT CCEECCCCCCCCCCC | 38.22 | 23749301 | |
| 232 | Acetylation | IAIDINNKKKQYCSQ EEEECCCCCCEEHHH | 57.78 | 25381059 | |
| 249 | Acetylation | ATDFVNPKEDLAKDQ CCCCCCCHHHHHCCC | 59.67 | 24489116 | |
| 254 | Acetylation | NPKEDLAKDQTIVEK CCHHHHHCCCHHHHH | 58.63 | 25381059 | |
| 341 | Acetylation | SEMGGLIKDYQKGAL HHHCCHHHHHHCCCE | 56.26 | 24489116 | |
| 349 | Acetylation | DYQKGALKVEEFITH HHHCCCEEHHHHHHC | 47.25 | 24489116 | |
| 361 | Acetylation | ITHRRPFKEINQAFE HHCCCCHHHHHHHHH | 61.44 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FADH_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FADH_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FADH_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
