| UniProt ID | BST1_YEAST | |
|---|---|---|
| UniProt AC | P43571 | |
| Protein Name | GPI inositol-deacylase | |
| Gene Name | BST1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 1029 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . |
|
| Protein Description | Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. Required for the transport of misfolded protein to the Golgi, although dipensable for the transport of many normal proteins.. | |
| Protein Sequence | MGIRRLVSVITRPIINKVNSSGQYSRVLATREDQDKASPKYMNNDKIAKKPYTYRLFSILGILSICSLLLISLLKPFNGADAPQCESIYMFPSYARIDGFDERYTPLAHKYHLYLYREQSVDREPLNGDELQLDGIPVLFIPGNAGSFRQCRSIASACSNIYFDSNTRATLRNENVRNLDFFTADFNEDFTAFHGETMLDQAEYLNDAIKYILSLYERTPDYPHPKPQSVIIVGHSMGGIVSRVMLTLKNHVPGSISTILTLSSPHAASPVTFDGDILKLYKNTNEYWRKQLSQNDSFFSKNISLVSITGGILDTTLPADYASVEDLVSLENGFTSFTTTIPDVWTPIDHLAIVWCKQLREVLARLLLESIDASKPEKVKPLNQRLQIARKLLLSGFEDYSWMNSKLNYPQENLQEFSDNFFSDYATLEMNDVLDFEMFNLEKWHNNYTKINIPSNISSTEHLHFTLLTSLDMPMIYFCTESRVNLSCITAVDSILTVPRSSKDTQFAADSSFGEAKNPFKAVSVGKNILQKYDYLMISKPTYGEFSEQEGMEDNQGFLLALLRNVSNVQIVNTTPSQILLFGEQLHLDGKDIEQVISFSNLWDSLLSYKLETKIEASNEGIASEETLFQPFIRQWVYEPFESKWHLNIINKSLDINMHNVAPFIPLNESEPRSLQLSFFIPPGMSLEAKMTINWSLTLKMLFIRYRLALASFPVAFIALVLSYQFYWYNKTSEFPSFDSTLGYILRKHGILMFFTLFLASPVVNNKLVQRILYLLDPVGLNYPFLLSERNMHANFYYLGIRDWFMSTIGILFGVMTVGLLALVSKIFGSLEILVIFLQRKLSKKNTEDKEAFDTIEHKAYGKGRLMASVLLLLLVFFHIPYQMAFVISLVIQIATCIRVALLKLSNNEQKLNLLNYNMTLLLLLLFVSAINIPIIIVFLHNVAIKWETSFRSHHNILAVAPIIFLVGNNSIFKMPNSVPLDTWDGKVTIILFVYLTVFSFIYGIRNLYWIHHLVNIICAWLLFFETIH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 19 | N-linked_Glycosylation | RPIINKVNSSGQYSR HHHHHHCCCCCCCEE | 31.87 | - | |
| 20 | Phosphorylation | PIINKVNSSGQYSRV HHHHHCCCCCCCEEE | 38.54 | 23749301 | |
| 21 | Phosphorylation | IINKVNSSGQYSRVL HHHHCCCCCCCEEEE | 25.39 | 19823750 | |
| 24 | Phosphorylation | KVNSSGQYSRVLATR HCCCCCCCEEEEEEC | 11.28 | 19823750 | |
| 25 | Phosphorylation | VNSSGQYSRVLATRE CCCCCCCEEEEEECC | 14.18 | 19823750 | |
| 30 | Phosphorylation | QYSRVLATREDQDKA CCEEEEEECCCCCCC | 30.36 | 19823750 | |
| 295 | N-linked_Glycosylation | WRKQLSQNDSFFSKN HHHHHHCCCCCCCCC | 43.44 | - | |
| 302 | N-linked_Glycosylation | NDSFFSKNISLVSIT CCCCCCCCEEEEEEC | 28.08 | - | |
| 447 | N-linked_Glycosylation | NLEKWHNNYTKINIP CHHHHHCCCCEEECC | 32.72 | - | |
| 456 | N-linked_Glycosylation | TKINIPSNISSTEHL CEEECCCCCCCCCCC | 32.57 | - | |
| 485 | N-linked_Glycosylation | FCTESRVNLSCITAV EECCCCCCHHHHEEE | 25.73 | - | |
| 542 | Phosphorylation | YLMISKPTYGEFSEQ EEEEECCCCCCCCHH | 48.14 | 27017623 | |
| 543 | Phosphorylation | LMISKPTYGEFSEQE EEEECCCCCCCCHHH | 24.16 | 27017623 | |
| 547 | Phosphorylation | KPTYGEFSEQEGMED CCCCCCCCHHHCCCC | 33.78 | 27017623 | |
| 565 | N-linked_Glycosylation | FLLALLRNVSNVQIV HHHHHHHCCCCCEEE | 41.35 | - | |
| 651 | N-linked_Glycosylation | KWHLNIINKSLDINM CEEEECCCCCCCEEC | 24.86 | - | |
| 668 | N-linked_Glycosylation | VAPFIPLNESEPRSL CCCCCCCCCCCCCCE | 45.45 | - | |
| 694 | N-linked_Glycosylation | LEAKMTINWSLTLKM CEEEEEECHHHHHHH | 17.08 | - | |
| 830 | Phosphorylation | LVSKIFGSLEILVIF HHHHHHCCHHHHHHH | 16.45 | 29688323 | |
| 843 | Phosphorylation | IFLQRKLSKKNTEDK HHHHHHHHCCCCCCH | 44.62 | 29688323 | |
| 918 | N-linked_Glycosylation | KLNLLNYNMTLLLLL HHHHHHHHHHHHHHH | 18.85 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BST1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BST1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BST1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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