TMN2_YEAST - dbPTM
TMN2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TMN2_YEAST
UniProt AC Q04562
Protein Name Transmembrane 9 superfamily member 2
Gene Name TMN2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 672
Subcellular Localization Vacuole membrane
Multi-pass membrane protein.
Protein Description With EMP70 and TMN3, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression. Acts downstream of RAS2 and TOR. Essential for cell adhesion and filamentous growth. May play a role as effector of cellular copper homeostasis..
Protein Sequence MKRGVWLLIYCYATLTKGFSLPGLSPTTYHSGDEIPLLVNRLTPSIYFQHQDEEGNDVSGDKEHFLYSYDYYNKRFHFCRPEHVEKQPESLGSVIFGDRIYNSPFQLNMLEEKECVALCKSTIPGKDAKFINTLIKSGFFQNWLVDGLPAARKAYDSRTKTNYYGTGFELGFTDVKQTVDGKAVPSTMEELTSEASNEDVILDARLPKNVKPNLVKTVELPYFVNHFDIEVEFHDRGNDNYRVVGVIVNPVSIERSSPGACSTTGKPLILDEDKDNEVYFTYSVKFVASDTVWATRWDKYLHIYDPQIQWFSLINFSVIVILLSSVVMHSLLRALKSDLARYNELNLDNEFHEDSGWKLGHGDVFRTPSKSMLLSILVGSGMQLFLMVMCSIFFAAVGLVSPVSRGSLPTVMFVLYALFGFVGSYASMGVYKFFRGPYWKANMILTPILLPGAIFLLIVIMNFFLLFAHSSGVIPARSLFFIILLWFLVSVPLSFAGSIVAHKQCNWDEHPTKTNQIARQIPYQPWYLRTAQATLIAGIFSFGSIAVELYFIYSSLWFNKIFYMFGFLLFSFLLLTLTTSLVTILITYYSLCLENWLWQWRSFIIGGLGCSIYTFIHSILFTKFKLGGVITVVLYLGYSLIISALCCVVTGAIGFFSSMFFIRKIYSAIKVE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
136UbiquitinationKFINTLIKSGFFQNW
HHHHHHHHCCCCCHH		47.8717644757
153UbiquitinationDGLPAARKAYDSRTK
CCCCHHHHHHHCCCC		46.7217644757
336UbiquitinationHSLLRALKSDLARYN
HHHHHHHHHHHHHHH		40.7223749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TMN2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TMN2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TMN2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TMN3_YEASTTMN3genetic
18178563
MOT3_YEASTMOT3physical
18719252
HSP71_YEASTSSA1physical
22940862
BUD31_YEASTBUD31genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
ARL1_YEASTARL1genetic
27708008
RV161_YEASTRVS161genetic
27708008
THRC_YEASTTHR4genetic
27708008
PEX19_YEASTPEX19genetic
27708008
BRE1_YEASTBRE1genetic
27708008
RV167_YEASTRVS167genetic
27708008
COG7_YEASTCOG7genetic
27708008
MED20_YEASTSRB2genetic
27708008
ENV10_YEASTENV10genetic
27708008
COG8_YEASTCOG8genetic
27708008
RAD14_YEASTRAD14genetic
27708008
COG6_YEASTCOG6genetic
27708008
COG5_YEASTCOG5genetic
27708008
RUD3_YEASTRUD3genetic
27708008
RS10A_YEASTRPS10Agenetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
YME1_YEASTYME1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TMN2_YEAST

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Related Literatures of Post-Translational Modification

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