TMN3_YEAST - dbPTM
TMN3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TMN3_YEAST
UniProt AC P40071
Protein Name Transmembrane 9 superfamily member 3
Gene Name TMN3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 706
Subcellular Localization Golgi apparatus membrane
Multi-pass membrane protein .
Protein Description With EMP70 and TMN2, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression. Acts downstream of RAS2 and TOR. Essential for cell adhesion and filamentous growth. May play a role as effector of cellular copper homeostasis..
Protein Sequence MRVRPKRSVITLMAIVVVMLILRNQFYSSRTRGHGQEPVISSSQKNLYDGWITPNFYRKGDPLELIVNKVESDLTQLPYAYYDLPFTCPPTMHKKPLHLSLNEIIRGDRKWESDYKLKFGEDNPCETLCARKTTKEGMQTLDKLVREGYVVQWLIDDELPAATTFISTTDHKKYYASGFPLGFIDPDTDKTYLHNHVMLVIRFHASDNDKNTIVGFEVYPRSVSDYHCPGASKNYEQYEIVIPEDENELTYLPFTYSVYWREEFEVDWNHRWDYFLNAGELSDEQSIQFHWMSLANSVGIVLSISFITLIIYVRVMYTDKSNSKSPKYMINIEGIETEDDLDDDKYGKYSVYTVAKDWIQNGRPNLFGLKVLILLVSFGVQFLFTIIGSLTISCSMNKLHNVRNSVLTMAILFFVLGAFMASFVGTRLSMVTKTKRTKANYLDDNRYLKDYKKFSPIFTILCGSSLPGIVMVSTFLLNSIVWAHDSTSALPFKTIVFFMSIYFIVCIPLSLFGGIVANNIPLPQYWLSGITKDESNSDGNGLFVPKSRAKFNPLVYCGIYLCGIFPLLVIYVEMQYVYKSLWLEKTTFYYFYGFLFLSIILLCVLTMEISIIGSYLLMRFCFEDKVVRNNWRWKCFEMGFSGGVYMELYSLYYIFAVLNIHGFSSILISICYSLIFNVMCSLGLGALSYLTASWFINKIYHQKVNL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
323PhosphorylationMYTDKSNSKSPKYMI
HCCCCCCCCCCCEEE		41.4228889911
337PhosphorylationINIEGIETEDDLDDD
EEEECCCCCCCCCCC		42.6721440633
438UbiquitinationVTKTKRTKANYLDDN
HHCCCCCCCCCCCCC		38.3723749301
546UbiquitinationGNGLFVPKSRAKFNP
CCCCCCCCHHHCCCH		47.4723749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TMN3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TMN3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TMN3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SC6B1_YEASTSBH1genetic
16269340
RGP1_YEASTRGP1genetic
16269340
GPI8_YEASTGPI8genetic
16269340
RIC1_YEASTRIC1genetic
16269340
RBD2_YEASTRBD2physical
18467557
RBD2_YEASTRBD2physical
22615397
YPQ3_YEASTRTC2genetic
27708008
MUP1_YEASTMUP1genetic
27708008
ASK10_YEASTASK10genetic
27708008
THIK_YEASTPOT1genetic
27708008
VPS53_YEASTVPS53genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
PUF3_YEASTPUF3genetic
27708008
ENV10_YEASTENV10genetic
27708008
SIW14_YEASTSIW14genetic
27708008
INO4_YEASTINO4genetic
27708008
TBP6_YEASTYTA6genetic
27708008
CGS5_YEASTCLB5genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TMN3_YEAST

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Related Literatures of Post-Translational Modification

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