| UniProt ID | YPQ3_YEAST | |
|---|---|---|
| UniProt AC | P38279 | |
| Protein Name | Probable vacuolar amino acid transporter YPQ3 | |
| Gene Name | RTC2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 296 | |
| Subcellular Localization |
Vacuole membrane Multi-pass membrane protein . Mitochondrion membrane Multi-pass membrane protein . |
|
| Protein Description | May function as an amino acid transporter mediating the export of cationic amino acids from the vacuole. Required for optimal growth in synthetic medium.. | |
| Protein Sequence | MKLIPIILNAKNLSGMAGSISICCWIVVFVPQIYENFRRQSAEGLSLLFIVLWLLGDIFNVMGAMMQNLLPTMIILAAYYTLADLILLIQCMWYDKEKKSILQEVKKNVDPVHLPPANPINETVLQDVFNEYEPLLPRIEEEDSQSYSSLELGRTIVVKERENFFNDFLIVSGVLIAGILSWYISYCSGLDNGIPKKKPAFEQINLPAQILGYLSAILYLGSRIPQIVLNFKRKSCEGVSFLFFLFACLGNTSFIISVLSASWLIGSAGTLLMDFTVFIQFFLYAKPKYEKILIDN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 106 | Ubiquitination | KSILQEVKKNVDPVH HHHHHHHHHCCCCCC | 17644757 | ||
| 107 | Ubiquitination | SILQEVKKNVDPVHL HHHHHHHHCCCCCCC | 17644757 | ||
| 146 | Phosphorylation | IEEEDSQSYSSLELG CCCCCCCCCCCCCCC | 27214570 | ||
| 147 | Phosphorylation | EEEDSQSYSSLELGR CCCCCCCCCCCCCCC | 27214570 | ||
| 149 | Phosphorylation | EDSQSYSSLELGRTI CCCCCCCCCCCCCEE | 27214570 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of YPQ3_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of YPQ3_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of YPQ3_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MED20_YEAST | SRB2 | genetic | 27708008 | |
| VPS53_YEAST | VPS53 | genetic | 27708008 | |
| YME1_YEAST | YME1 | genetic | 27708008 | |
| BOL3_YEAST | AIM1 | genetic | 27708008 | |
| MIX14_YEAST | MIX14 | genetic | 27708008 | |
| HIBCH_YEAST | EHD3 | genetic | 27708008 | |
| SLX8_YEAST | SLX8 | genetic | 27708008 | |
| WWM1_YEAST | WWM1 | genetic | 27708008 | |
| CGR1_YEAST | CGR1 | genetic | 27708008 | |
| YG5Q_YEAST | YGR273C | genetic | 27708008 | |
| SNF6_YEAST | SNF6 | genetic | 27708008 | |
| SODM_YEAST | SOD2 | genetic | 27708008 | |
| YJ09_YEAST | YJR039W | genetic | 27708008 | |
| CYT2_YEAST | CYT2 | genetic | 27708008 | |
| YK104_YEAST | YKR104W | genetic | 27708008 | |
| SST2_YEAST | SST2 | genetic | 27708008 | |
| YMW4_YEAST | YMR074C | genetic | 27708008 | |
| LSM7_YEAST | LSM7 | genetic | 27708008 | |
| PUR6_YEAST | ADE2 | genetic | 27708008 | |
| UBP16_YEAST | UBP16 | genetic | 27708008 | |
| SAM3_YEAST | SAM3 | genetic | 27708008 | |
| UBA3_YEAST | UBA3 | genetic | 27708008 | |
| MRL1_YEAST | MRL1 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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