WWM1_YEAST - dbPTM
WWM1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID WWM1_YEAST
UniProt AC P43582
Protein Name WW domain-containing protein WWM1
Gene Name WWM1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 211
Subcellular Localization Cytoplasm. Nucleus. Mitochondrion.
Protein Description Involved in apoptosis. May play a role in nuclear function controlling cellular proliferation coupled to mitochondrial biogenesis. Causes impaired growth when overexpressed..
Protein Sequence MAQSKSNPPQVPSGWKAVFDDEYQTWYYVDLSTNSSQWEPPRGTTWPRPKGPPPGVNNEKSSRQQADQAPPPYSSQSTPQVQAGAQAQQPRYYQPQQPQYPQYPQQQRYYPQQAPMPAAAPQQAYYGTAPSTSKGSGHGGAMMGGLLGVGAGLLGGAMLEHAFDDHNYDGPDTVVVENNYYGDDAGGSDGGFDDAGGFDGGFDDGFDGSDF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
50UbiquitinationGTTWPRPKGPPPGVN
CCCCCCCCCCCCCCC		82.4423749301
60UbiquitinationPPGVNNEKSSRQQAD
CCCCCCHHHHHHHHH		56.7223749301
60AcetylationPPGVNNEKSSRQQAD
CCCCCCHHHHHHHHH		56.7225381059
61PhosphorylationPGVNNEKSSRQQADQ
CCCCCHHHHHHHHHC		25.2823749301
73PhosphorylationADQAPPPYSSQSTPQ
HHCCCCCCCCCCCHH		27.0828132839
74PhosphorylationDQAPPPYSSQSTPQV
HCCCCCCCCCCCHHH		27.8928889911
75PhosphorylationQAPPPYSSQSTPQVQ
CCCCCCCCCCCHHHH		23.4724909858
77PhosphorylationPPPYSSQSTPQVQAG
CCCCCCCCCHHHHCC		43.9628889911
78PhosphorylationPPYSSQSTPQVQAGA
CCCCCCCCHHHHCCC		15.3123749301
128PhosphorylationPQQAYYGTAPSTSKG
CCCCEEECCCCCCCC		21.1921082442
131PhosphorylationAYYGTAPSTSKGSGH
CEEECCCCCCCCCCC		42.7323749301
132PhosphorylationYYGTAPSTSKGSGHG
EEECCCCCCCCCCCH		33.1419779198
133PhosphorylationYGTAPSTSKGSGHGG
EECCCCCCCCCCCHH		39.0828152593
134UbiquitinationGTAPSTSKGSGHGGA
ECCCCCCCCCCCHHH		58.1322106047
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of WWM1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of WWM1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CKS1_YEASTCKS1genetic
19269370
SHO1_YEASTSHO1genetic
19269370
KCC1_YEASTCMK1genetic
19269370
FAB1_YEASTFAB1genetic
19269370
PVH1_YEASTYVH1genetic
19269370
WWM1_YEASTWWM1physical
19345193
YJ66_YEASTYJR096Wphysical
16606443
MDHP_YEASTMDH3physical
16606443
PHSG_YEASTGPH1physical
16606443
NPT1_YEASTNPT1physical
16606443
PYC1_YEASTPYC1physical
16606443
LHP1_YEASTLHP1physical
16606443
EIF3J_YEASTHCR1physical
16606443
PCKA_YEASTPCK1physical
16606443
ENO2_YEASTENO2physical
16606443
MASY_YEASTMLS1physical
16606443
STM1_YEASTSTM1physical
16606443
AATC_YEASTAAT2physical
16606443
FRDS_YEASTFRD1physical
16606443
PURA_YEASTADE12physical
16606443
UBP10_YEASTUBP10physical
16606443
MVP1_YEASTMVP1physical
16606443
DUS1_YEASTDUS1physical
16606443
KYNU_YEASTBNA5physical
16606443
YIG0_YEASTYIL060Wphysical
16606443
IMDH2_YEASTIMD2physical
16606443
YHE2_YEASTYHL042Wphysical
16606443
NOP3_YEASTNPL3physical
16606443
YD061_YEASTYDR061Wphysical
16606443
CALM_YEASTCMD1physical
16606443
YBQ6_YEASTYBR056Wphysical
16606443
TKT1_YEASTTKL1physical
16606443
FMP40_YEASTFMP40physical
16606443
DYR_YEASTDFR1physical
16606443
PMG3_YEASTGPM3physical
16606443
PRP2_YEASTPRP2physical
16606443
GOR1_YEASTGOR1physical
16606443
IPA3_YEASTPAI3physical
16606443
TAL1_YEASTTAL1physical
16606443
UBI4P_YEASTUBI4physical
16606443
RPC5_YEASTRPC37physical
16606443
PTE1_YEASTTES1physical
16606443
PTPA1_YEASTRRD1physical
16606443
DOG2_YEASTDOG2physical
16606443
RIR4_YEASTRNR4physical
16606443
LSB1_YEASTLSB1physical
16606443
YG2W_YEASTYGR111Wphysical
16606443
SIP2_YEASTSIP2physical
16606443
SMT3_YEASTSMT3physical
16606443
KAD2_YEASTADK1physical
16606443
TCPA_YEASTTCP1physical
16606443
HEM6_YEASTHEM13physical
16606443
PTP1_YEASTPTP1physical
16606443
HOSM_YEASTLYS21physical
16606443
ARP2_YEASTARP2physical
16606443
RS14A_YEASTRPS14Aphysical
16606443
PP2C4_YEASTPTC4genetic
27708008
AGP1_YEASTAGP1genetic
27708008
PEX19_YEASTPEX19genetic
27708008
ECM18_YEASTECM18genetic
27708008
PEX5_YEASTPEX5genetic
27708008
ITR1_YEASTITR1genetic
27708008
AST2_YEASTAST2genetic
27708008
MED5_YEASTNUT1genetic
27708008
ASK10_YEASTASK10genetic
27708008
YHE4_YEASTYHL044Wgenetic
27708008
YI014_YEASTYIL014C-Agenetic
27708008
CSM2_YEASTCSM2genetic
27708008
YJE3_YEASTYJL043Wgenetic
27708008
CYC1_YEASTCYC1genetic
27708008
EAF6_YEASTEAF6genetic
27708008
YL040_YEASTAFB1genetic
27708008
YL283_YEASTYLR283Wgenetic
27708008
CSR1_YEASTCSR1genetic
27708008
SEI1_YEASTFLD1genetic
27708008
RM39_YEASTMRPL39genetic
27708008
GTR1_YEASTGTR1genetic
27708008
CG11_YEASTCLN1genetic
27708008
YM59_YEASTYMR209Cgenetic
27708008
ELP6_YEASTELP6genetic
27708008
SIN3_YEASTSIN3genetic
27708008
TAT2_YEASTTAT2genetic
27708008
ITR2_YEASTITR2genetic
27708008
DCS2_YEASTDCS2genetic
27708008
KA120_YEASTKAP120genetic
27708008
ENV7_YEASTENV7genetic
27708008
MED1_YEASTMED1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of WWM1_YEAST

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Related Literatures of Post-Translational Modification

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