PP2C4_YEAST - dbPTM
PP2C4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PP2C4_YEAST
UniProt AC P38089
Protein Name Protein phosphatase 2C homolog 4
Gene Name PTC4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 393
Subcellular Localization
Protein Description
Protein Sequence MGQLLSHPLTEKTIEYNEYKNNQASTGIVPRFYNCVGSMQGYRLTQEDAHLIRNENSVVYVRFFNPFIDKYETLSLNVFAVFDGHGGDDCSKFLSGGRHHRDGNGSSNGNGEPNAGLIKWIAYSFENHHYTSTTNNDSSKFKRSFNTLEGLVSQIFKDAFILQDEELYRHFANSSCGSTAVVACIINEESLYVANCGDSRCILSSKSNGIKTMSFDHKPQHIGELIRINDNGGTVSLGRVGGVLALSRAFSDFQFKRGVTYPHRRTKLTNITQNLTYGTPPQEAQVTVEPDVLMHKIDYSKDEFLVLACDGIWDIYNNKQLIHFIKYHLVSGTKLDTIITKLLDHGIAQANSNTGVGFDNMTAIIVVLNRKGETLQDWFNKMKTRLERERGLV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationQLLSHPLTEKTIEYN
CCCCCCCCHHEECHH
39.6330377154
20UbiquitinationTIEYNEYKNNQASTG
EECHHHCCCCCCCCC
43.1523749301
71PhosphorylationFNPFIDKYETLSLNV
ECCCCCCCCEEEEEE
15.4828889911
73PhosphorylationPFIDKYETLSLNVFA
CCCCCCCEEEEEEEE
20.6828889911
75PhosphorylationIDKYETLSLNVFAVF
CCCCCEEEEEEEEEE
25.8928889911
107PhosphorylationHRDGNGSSNGNGEPN
CCCCCCCCCCCCCCC
50.5927214570
247PhosphorylationVGGVLALSRAFSDFQ
HHHHHHHHHHCCCCC
18.8927017623
251PhosphorylationLALSRAFSDFQFKRG
HHHHHHCCCCCCCCC
36.2128889911
279PhosphorylationTQNLTYGTPPQEAQV
CCCCCCCCCCCCCEE
22.7528889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PP2C4_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PP2C4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PP2C4_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PAA1_YEASTPAA1physical
11805826
SND1_YEASTYDR186Cphysical
11805826
VHS1_YEASTVHS1physical
11805837
GIN4_YEASTGIN4physical
11805837
PAA1_YEASTPAA1physical
11805837
PAA1_YEASTPAA1physical
16554755
SSB1_YEASTSSB1physical
16429126
SND1_YEASTYDR186Cphysical
16429126
PAA1_YEASTPAA1physical
16429126
SPC3_YEASTSPC3physical
18467557
KCS1_YEASTKCS1genetic
19269370
VHS1_YEASTVHS1genetic
19269370
ISC1_YEASTISC1genetic
19269370
GET1_YEASTGET1genetic
19269370
TOS3_YEASTTOS3genetic
19269370
KHSE_YEASTTHR1genetic
19269370
SET2_YEASTSET2genetic
19269370
ADK_YEASTADO1genetic
19269370
YPT6_YEASTYPT6genetic
19269370
TCO89_YEASTTCO89genetic
19269370
CLH_YEASTCHC1physical
20489023
PAA1_YEASTPAA1physical
20489023
IMA1_YEASTSRP1physical
20489023
FUS3_YEASTFUS3genetic
21127252
PPA3_YEASTPHO3genetic
21127252
TEC1_YEASTTEC1genetic
21127252
RXT2_YEASTRXT2genetic
21127252
PPA5_YEASTPHO5genetic
21127252
PP2C2_YEASTPTC2genetic
25088474
TPS2_YEASTTPS2genetic
27708008
HMI1_YEASTHMI1genetic
27708008
THRC_YEASTTHR4genetic
27708008
MTU1_YEASTSLM3genetic
27708008
INO2_YEASTINO2genetic
27708008
UME6_YEASTUME6genetic
27708008
BCS1_YEASTBCS1genetic
27708008
RV167_YEASTRVS167genetic
27708008
UBP3_YEASTUBP3genetic
27708008
YGS6_YEASTYGL176Cgenetic
27708008
CHO2_YEASTCHO2genetic
27708008
VPS53_YEASTVPS53genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
EMC2_YEASTEMC2genetic
27708008
UPS1_YEASTUPS1genetic
27708008
SEI1_YEASTFLD1genetic
27708008
MSS1_YEASTMSS1genetic
27708008
SSO2_YEASTSSO2genetic
27708008
SAP30_YEASTSAP30genetic
27708008
SIW14_YEASTSIW14genetic
27708008
ASE1_YEASTASE1genetic
27708008
SNC2_YEASTSNC2genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
SLT2_YEASTSLT2physical
25736922

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PP2C4_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP