VHS1_YEAST - dbPTM
VHS1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID VHS1_YEAST
UniProt AC Q03785
Protein Name Serine/threonine-protein kinase VHS1
Gene Name VHS1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 461
Subcellular Localization Cytoplasm .
Protein Description Probable serine/threonine protein kinase involved in the G1-S transition..
Protein Sequence MMMFHNCRINNYLITSQIGEGAYGLVYRALDIRTDRQYAIKAVVQSYGVSKEADMGNDKIHKNSVKLQKKLAKLFKESKNVVRVPSIDLESIENMSEEDFKKLPHYKEISLHLRVHHHKNIVTIHEVLQSAVCTFIVMDYYPTDLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFGLSTTSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQILPLSDDFYSLLSKILQVNPKNRMSLQELMKEVSSITSFTNEGPLSKVPPLSKSVYEKFVSPVDNTNENLSPKSYVYMHDSKAAKNLSYTSSSEEEDGIKEGIDDDNGSRSGSFGTLDTDTGLHSSFTSTSCESDNECSKISNKFSLFEKKFNELRMSSSSLTN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
51UbiquitinationVQSYGVSKEADMGND
HHHHCCCCCCCCCCC
55.2923749301
86PhosphorylationKNVVRVPSIDLESIE
CCEEECCCCCHHHHC
26.3628889911
368PhosphorylationDNTNENLSPKSYVYM
CCCCCCCCCCCEEEE
41.6925752575
386PhosphorylationKAAKNLSYTSSSEEE
HHHHHCCCCCCCCCC
17.5128889911
387PhosphorylationAAKNLSYTSSSEEED
HHHHCCCCCCCCCCC
20.8219795423
388PhosphorylationAKNLSYTSSSEEEDG
HHHCCCCCCCCCCCC
24.5119795423
389PhosphorylationKNLSYTSSSEEEDGI
HHCCCCCCCCCCCCC
33.6919795423
390PhosphorylationNLSYTSSSEEEDGIK
HCCCCCCCCCCCCCC
49.1219795423
406PhosphorylationGIDDDNGSRSGSFGT
CCCCCCCCCCCCCEE
29.5428889911
455PhosphorylationKFNELRMSSSSLTN-
HHHHHHHCCCCCCC-
22.1921551504
458PhosphorylationELRMSSSSLTN----
HHHHCCCCCCC----
40.9521551504
460PhosphorylationRMSSSSLTN------
HHCCCCCCC------
40.6128889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of VHS1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of VHS1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of VHS1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TPS1_YEASTTPS1physical
11805837
PAA1_YEASTPAA1physical
11805837
PP2C4_YEASTPTC4physical
11805837
MER1_YEASTMER1physical
11805837
SEF1_YEASTSEF1physical
11805837
SKT5_YEASTSKT5physical
11805837
SPT16_YEASTSPT16physical
11805837
NUM1_YEASTNUM1physical
11805837
SYF1_YEASTSYF1physical
11805837
KAPR_YEASTBCY1physical
16319894
PANE_YEASTPAN5physical
16319894
MET7_YEASTSTR2physical
16319894
SOL1_YEASTSOL1physical
16319894
MBR1_YEASTMBR1physical
16319894
UTR1_YEASTUTR1physical
16319894
6P21_YEASTPFK26physical
16319894
SEF1_YEASTSEF1physical
16319894
AKL1_YEASTAKL1physical
16319894
NCL1_YEASTNCL1physical
16319894
STR3_YEASTSTR3physical
16319894
SIP5_YEASTSIP5physical
16319894
SOL2_YEASTSOL2physical
16319894
MGA1_YEASTMGA1physical
16319894
ATS1_YEASTATS1genetic
20093466
CSG2_YEASTCSG2genetic
20093466
PEX32_YEASTPEX32genetic
20093466
RV161_YEASTRVS161genetic
20093466
YCZ2_YEASTYCR102Cgenetic
20093466
NRG1_YEASTNRG1genetic
20093466
TPS2_YEASTTPS2genetic
20093466
VPS41_YEASTVPS41genetic
20093466
RV167_YEASTRVS167genetic
20093466
DSE1_YEASTDSE1genetic
20093466
RIM15_YEASTRIM15genetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
DBF2_YEASTDBF2genetic
20093466
SLH1_YEASTSLH1genetic
20093466
SPO13_YEASTSPO13genetic
20093466
YIQ1_YEASTYIL161Wgenetic
20093466
HAP4_YEASTHAP4genetic
20093466
YKH1_YEASTYKL071Wgenetic
20093466
COX12_YEASTCOX12genetic
20093466
ADY4_YEASTADY4genetic
20093466
ATP10_YEASTATP10genetic
20093466
SSO2_YEASTSSO2genetic
20093466
HFA1_YEASTHFA1genetic
20093466
YNK8_YEASTYNL108Cgenetic
20093466
MSH2_YEASTMSH2genetic
20093466
ALG8_YEASTALG8genetic
20093466
ECM23_YEASTECM23genetic
20093466
SOL2_YEASTSOL2physical
20159853
ASK10_YEASTASK10physical
20489023
BMS1_YEASTBMS1physical
20489023
CDC14_YEASTCDC14physical
20489023
YAP4_YEASTCIN5physical
20489023
CSM1_YEASTCSM1physical
20489023
CYAA_YEASTCYR1physical
20489023
ELP2_YEASTELP2physical
20489023
ELP3_YEASTELP3physical
20489023
FTHC_YEASTFAU1physical
20489023
PP12_YEASTGLC7physical
20489023
ELP1_YEASTIKI3physical
20489023
IMPX_YEASTIMP2physical
20489023
LRS4_YEASTLRS4physical
20489023
MAM33_YEASTMAM33physical
20489023
MSN1_YEASTMSN1physical
20489023
NET1_YEASTNET1physical
20489023
NUM1_YEASTNUM1physical
20489023
PP2C4_YEASTPTC4physical
20489023
RCL1_YEASTRCL1physical
20489023
RPA2_YEASTRPA135physical
20489023
RRN10_YEASTRRN10physical
20489023
RRN9_YEASTRRN9physical
20489023
SEF1_YEASTSEF1physical
20489023
SIR2_YEASTSIR2physical
20489023
TOF2_YEASTTOF2physical
20489023
YG51_YEASTYGR237Cphysical
20489023
MRX6_YEASTYNL295Wphysical
20489023
RGC1_YEASTRGC1physical
20489023
ACK1_YEASTACK1physical
21460040
ARF3_YEASTARF3physical
21460040
3HAO_YEASTBNA1physical
21460040
CDC13_YEASTCDC13physical
21460040
DIB1_YEASTDIB1physical
21460040
FMP46_YEASTFMP46physical
21460040
MPC54_YEASTMPC54physical
21460040
RIM4_YEASTRIM4physical
21460040
RKM4_YEASTRKM4physical
21460040
SDS22_YEASTSDS22physical
21460040
SIP2_YEASTSIP2physical
21460040
SKY1_YEASTSKY1physical
21460040
UBP6_YEASTUBP6physical
21460040
UBP7_YEASTUBP7physical
21460040
YD177_YEASTYDL177Cphysical
21460040
CMS1_YEASTCMS1physical
21460040
YM11A_YEASTYML045W-Aphysical
21460040
RGC1_YEASTRGC1physical
21460040
YND5_YEASTYNL035Cgenetic
22282571
HAP4_YEASTHAP4genetic
22282571
WTM2_YEASTWTM2genetic
22282571
SCD5_YEASTSCD5genetic
22282571
CG12_YEASTCLN2genetic
22282571
RTP1_YEASTRTP1genetic
22282571
RAD24_YEASTRAD24genetic
22282571
MAK16_YEASTMAK16genetic
22282571
SHS1_YEASTSHS1genetic
22282571
DML1_YEASTDML1genetic
22282571
NOC4_YEASTNOC4genetic
22282571
FLO10_YEASTFLO10genetic
22282571
TCPH_YEASTCCT7genetic
22282571
ENT2_YEASTENT2genetic
22282571
MET4_YEASTMET4genetic
22282571
PP2A1_YEASTPPH21genetic
22282571
CWH43_YEASTCWH43genetic
22282571
GAL80_YEASTGAL80genetic
22282571
YGY5_YEASTYGL235Wgenetic
22282571
RV167_YEASTRVS167genetic
22282571
RV161_YEASTRVS161genetic
22282571
SLH1_YEASTSLH1genetic
22282571
RIM15_YEASTRIM15genetic
22282571
ADY4_YEASTADY4genetic
22282571
TPS2_YEASTTPS2genetic
22282571
NRG1_YEASTNRG1genetic
22282571
ECM23_YEASTECM23genetic
22282571
ATP10_YEASTATP10genetic
22282571
YCZ2_YEASTYCR102Cgenetic
22282571
DBF2_YEASTDBF2genetic
22282571
CSG2_YEASTCSG2genetic
22282571
PEX32_YEASTPEX32genetic
22282571
YNK8_YEASTYNL108Cgenetic
22282571
SSO2_YEASTSSO2genetic
22282571
VPS41_YEASTVPS41genetic
22282571
YIQ1_YEASTYIL161Wgenetic
22282571
HFA1_YEASTHFA1genetic
22282571
YKH1_YEASTYKL071Wgenetic
22282571
COX12_YEASTCOX12genetic
22282571
DSE1_YEASTDSE1genetic
22282571
ALG8_YEASTALG8genetic
22282571
SPO13_YEASTSPO13genetic
22282571
PEX32_YEASTPEX32genetic
27708008
SEC66_YEASTSEC66genetic
27708008
MGR1_YEASTMGR1genetic
27708008
RV161_YEASTRVS161genetic
27708008
RIM1_YEASTRIM1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
VPS41_YEASTVPS41genetic
27708008
PT122_YEASTPET122genetic
27708008
VTC2_YEASTVTC2genetic
27708008
RIM15_YEASTRIM15genetic
27708008
YGY5_YEASTYGL235Wgenetic
27708008
DBF2_YEASTDBF2genetic
27708008
SLH1_YEASTSLH1genetic
27708008
SNF6_YEASTSNF6genetic
27708008
PTK2_YEASTPTK2genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
YKH1_YEASTYKL071Wgenetic
27708008
FRA1_YEASTFRA1genetic
27708008
COX12_YEASTCOX12genetic
27708008
ATP10_YEASTATP10genetic
27708008
MLH1_YEASTMLH1genetic
27708008
SSO2_YEASTSSO2genetic
27708008
PFKA2_YEASTPFK2genetic
27708008
YNK8_YEASTYNL108Cgenetic
27708008
ECM23_YEASTECM23genetic
27708008
EF1G1_YEASTCAM1genetic
27708008
SUR1_YEASTSUR1genetic
27708008
QCR2_YEASTQCR2genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of VHS1_YEAST

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Related Literatures of Post-Translational Modification

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