FLO10_YEAST - dbPTM
FLO10_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FLO10_YEAST
UniProt AC P36170
Protein Name Flocculation protein FLO10
Gene Name FLO10
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1169
Subcellular Localization Secreted, cell wall. Membrane
Lipid-anchor, GPI-anchor .
Protein Description Cell wall protein that participates directly in adhesive cell-cell interactions during yeast flocculation, a reversible, asexual and Ca(2+)-dependent process in which cells adhere to form aggregates (flocs) consisting of thousands of cells. The lectin-like protein sticks out of the cell wall of flocculent cells and selectively binds mannose residues in the cell walls of adjacent cells. Activity is inhibited by mannose, glucose, maltose and sucrose. Also involved in cell-substrate adhesion, haploid invasive growth and diploid pseudohyphae formation..
Protein Sequence MPVAARYIFLTGLFLLSVANVALGTTEACLPAGEKKNGMTINFYQYSLKDSSTYSNPSYMAYGYADAEKLGSVSGQTKLSIDYSIPCNGASDTCACSDDDATEYSASQVVPVKRGVKLCSDNTTLSSKTEKRENDDCDQGAAYWSSDLFGFYTTPTNVTVEMTGYFLPPKTGTYTFGFATVDDSAILSVGGNVAFECCKQEQPPITSTDFTINGIKPWNADAPTDIKGSTYMYAGYYYPIKIVYSNAVSWGTLPVSVVLPDGTEVNDDFEGYVFSFDDNATQAHCSVPNPAEHARTCVSSATSSWSSSEVCTECTETESTSYVTPYVTSSSWSSSEVCTECTETESTSTSTPYVTSSSSSSSEVCTECTETESTSYVTPYVSSSTAAANYTSSFSSSSEVCTECTETESTSTSTPYVTSSSWSSSEVCTECTETESTSYVTPYVSSSTAAANYTSSFSSSSEVCTECTETESTSTSTPYVTSSSSSSSEVCTECTETESTSYVTPYVSSSTAAANYTSSFSSSSEVCTECTETESTSTSTPYVTSSSWSSSEVCTECTETESTSYVTPYVSSSTAAANYTSSFSSSSEVCTECTETESTSTSTPYATSSTGTATSFTASTSNTMTSLVQTDTTVSFSLSSTVSEHTNAPTSSVESNASTFISSNKGSVKSYVTSSIHSITPMYPSNQTVTSSSVVSTPITSESSESSASVTILPSTITSEFKPSTMKTKVVSISSSPTNLITSYDTTSKDSTVGSSTSSVSLISSISLPSSYSASSEQIFHSSIVSSNGQALTSFSSTKVSSSESSESHRTSPTTSSESGIKSSGVEIESTSTSSFSFHETSTASTSVQISSQFVTPSSPISTVAPRSTGLNSQTESTNSSKETMSSENSASVMPSSSATSPKTGKVTSDETSSGFSRDRTTVYRMTSETPSTNEQTTLITVSSCESNSCSNTVSSAVVSTATTTINGITTEYTTWCPLSATELTTVSKLESEEKTTLITVTSCESGVCSETASPAIVSTATATVNDVVTVYSTWSPQATNKLAVSSDIENSASKASFVSEAAETKSISRNNNFVPTSGTTSIETHTTTTSNASENSDNVSASEAVSSKSVTNPVLISVSQQPRGTPASSMIGSSTASLEMSSYLGIANHLLTNSGISIFIASLLLAIV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
122N-linked_GlycosylationGVKLCSDNTTLSSKT
CEEECCCCCCCCCCC		20.76-
157N-linked_GlycosylationGFYTTPTNVTVEMTG
CEEECCCCEEEEEEE		28.76-
279N-linked_GlycosylationYVFSFDDNATQAHCS
EEEECCCCCCEEEEC		46.89-
389N-linked_GlycosylationSSSTAAANYTSSFSS
CCCCCCHHCCCCCCC		35.57-
452N-linked_GlycosylationSSSTAAANYTSSFSS
CCCCCCHHCCCCCCC		35.57-
515N-linked_GlycosylationSSSTAAANYTSSFSS
CCCCCCHHCCCCCCC		35.57-
578N-linked_GlycosylationSSSTAAANYTSSFSS
CCCCCCHHCCCCCCC		35.57-
656N-linked_GlycosylationPTSSVESNASTFISS
CCCCCCCCCCEEEEC		25.14-
686N-linked_GlycosylationITPMYPSNQTVTSSS
CCCCCCCCCEECCCC		36.72-
879N-linked_GlycosylationNSQTESTNSSKETMS
CCCCCCCCCCCCCCC		54.27-
892PhosphorylationMSSENSASVMPSSSA
CCCCCCCCCCCCCCC		20.8319779198
896PhosphorylationNSASVMPSSSATSPK
CCCCCCCCCCCCCCC		20.8719779198
1092N-linked_GlycosylationTHTTTTSNASENSDN
EEEECCCCCCCCCCC		45.45-
1099N-linked_GlycosylationNASENSDNVSASEAV
CCCCCCCCCCHHHHH		29.48-
1146GPI-anchorLEMSSYLGIANHLLT
HHHHHHHHHHHHHHH		14.55-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FLO10_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FLO10_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FLO10_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ASK10_YEASTASK10genetic
27708008
TBP7_YEASTYTA7genetic
27708008
ACE2_YEASTACE2genetic
27708008
RL19A_YEASTRPL19Bgenetic
27708008
RL19B_YEASTRPL19Bgenetic
27708008
PLPHP_YEASTYBL036Cgenetic
27708008
DSF2_YEASTDSF2genetic
27708008
NTC20_YEASTNTC20genetic
27708008
RL13A_YEASTRPL13Agenetic
27708008
TPS2_YEASTTPS2genetic
27708008
PUF6_YEASTPUF6genetic
27708008
ODPA_YEASTPDA1genetic
27708008
PFD3_YEASTPAC10genetic
27708008
RS23A_YEASTRPS23Agenetic
27708008
RS23B_YEASTRPS23Agenetic
27708008
BTN2_YEASTBTN2genetic
27708008
PSD10_YEASTNAS6genetic
27708008
PHO81_YEASTPHO81genetic
27708008
AP3B_YEASTAPL6genetic
27708008
PIH1_YEASTPIH1genetic
27708008
MSC7_YEASTMSC7genetic
27708008
ATG32_YEASTATG32genetic
27708008
PHO86_YEASTPHO86genetic
27708008
YJQ3_YEASTYJL163Cgenetic
27708008
ELF1_YEASTELF1genetic
27708008
PEX12_YEASTPEX12genetic
27708008
ATG16_YEASTATG16genetic
27708008
SCS7_YEASTSCS7genetic
27708008
YNE6_YEASTYNL046Wgenetic
27708008
FAR11_YEASTFAR11genetic
27708008
COQ10_YEASTCOQ10genetic
27708008
RLA2_YEASTRPP2Agenetic
27708008
PNT1_YEASTPNT1genetic
27708008
LGE1_YEASTLGE1genetic
27708008
TBP6_YEASTYTA6genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
BEM3_YEASTBEM3genetic
27708008
KIP2_YEASTKIP2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FLO10_YEAST

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Related Literatures of Post-Translational Modification

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