| UniProt ID | PFD3_YEAST | |
|---|---|---|
| UniProt AC | P48363 | |
| Protein Name | Prefoldin subunit 3 | |
| Gene Name | PAC10 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 199 | |
| Subcellular Localization | ||
| Protein Description | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.. | |
| Protein Sequence | MDTLFNSTEKNARGIPQAPFIENVNEIIKDPSDFELCFNKFQERLSKYKFMQESKLATIKQLKTRIPDLENTLKICQSLRNHSDEGDESDEPILLHYQLNDTLYTKAQVDIPEDRADLKVGLWLGADVMLEYPIDEAIELLKKKLADSEQSLTVSTEDVEFLRENITTMEVNCARLYNWDVQRRQDLKQAQEGTKNLKI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MDTLFNST -------CCCCCCCC | 8.84 | 22814378 | |
| 54 | Phosphorylation | KYKFMQESKLATIKQ HCHHHHHHHHHHHHH | 18.97 | 27017623 | |
| 55 | Ubiquitination | YKFMQESKLATIKQL CHHHHHHHHHHHHHH | 41.19 | 23749301 | |
| 55 | Acetylation | YKFMQESKLATIKQL CHHHHHHHHHHHHHH | 41.19 | 24489116 | |
| 89 | Phosphorylation | HSDEGDESDEPILLH CCCCCCCCCCCEEEE | 52.60 | 21440633 | |
| 195 | Acetylation | KQAQEGTKNLKI--- HHHHHHHCCCCC--- | 71.75 | 25381059 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PFD3_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PFD3_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PFD3_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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