| UniProt ID | GAS5_YEAST | |
|---|---|---|
| UniProt AC | Q08193 | |
| Protein Name | 1,3-beta-glucanosyltransferase GAS5 | |
| Gene Name | GAS5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 484 | |
| Subcellular Localization |
Secreted, cell wall . Membrane Lipid-anchor, GPI-anchor . Covalently-linked GPI-modified cell wall protein (GPI-CWP). |
|
| Protein Description | Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall biosynthesis and morphogenesis.. | |
| Protein Sequence | MLLRSLTSAFVLSAGLAQAASSSNSSTPSIEIKGNAFFNSESGERFYIRGVDYQPGGSSNLTDPLADASVCDRDVPVLKDLGINTVRVYTVDNSQDHSHCMKLLQENGIYLILDVNTPTSAISRYDPACSYNADYLQNVFATIDTFADYDNVLGFFAGNEVINSVNTTNTATYVKAVVRDMKKYIKARKYRQIPVGYSAADIVANRQLAAEYFNCGDEADARIDMFGVNDYSWCGESSFVVSGYSTKMKLYQDYSVPVFLSEFGCNQVKSSRPFTEIEAIYSTQMSSVFSGGLVYEYSNETNNYGLVQIDGDKVTKLTDFENLKNEYSKVSNPEGNGGYSTSNNYSTCPDYEKGVWEANNTLPAMPSAASAYFTSGAGSPMGTGIATQQSCDAKDDDDEEDDDTSSSSSSSSSSSSSASSSSESSSSTSKASSSSPSASETSLLKSAASATSSSQSSSKSKGAAGIIEIPLIFRALAELYNLVL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 24 | N-linked_Glycosylation | AQAASSSNSSTPSIE HHHHHCCCCCCCCEE | 41.76 | - | |
| 60 | N-linked_Glycosylation | YQPGGSSNLTDPLAD CCCCCCCCCCCCCCC | 48.97 | - | |
| 166 | N-linked_Glycosylation | NEVINSVNTTNTATY CCEEECCCCCCHHHH | 40.79 | - | |
| 265 | Glutathionylation | VFLSEFGCNQVKSSR CHHHHHCCCCCCCCC | 3.80 | 22833525 | |
| 299 | N-linked_Glycosylation | GLVYEYSNETNNYGL CEEEEEECCCCCEEE | 60.24 | - | |
| 324 | Acetylation | LTDFENLKNEYSKVS ECCHHHHHHHHHCCC | 60.35 | 24489116 | |
| 344 | N-linked_Glycosylation | GGYSTSNNYSTCPDY CCCCCCCCCCCCCCH | 31.72 | - | |
| 359 | N-linked_Glycosylation | EKGVWEANNTLPAMP HCCCEECCCCCCCCC | 30.42 | - | |
| 462 | GPI-anchor | QSSSKSKGAAGIIEI CCCCCCCCCCHHHHH | 27.96 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GAS5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GAS5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GAS5_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| GAS1_YEAST | GAS1 | genetic | 16269340 | |
| PGA3_YEAST | PGA3 | genetic | 16269340 | |
| PHO88_YEAST | PHO88 | physical | 16093310 | |
| ELO2_YEAST | ELO2 | physical | 16093310 | |
| POM33_YEAST | POM33 | physical | 16093310 | |
| COQ4_YEAST | COQ4 | genetic | 21623372 | |
| CYS3_YEAST | CYS3 | genetic | 21623372 | |
| PFKA1_YEAST | PFK1 | genetic | 21623372 | |
| COX6_YEAST | COX6 | genetic | 21623372 | |
| KCS1_YEAST | KCS1 | genetic | 21623372 | |
| GSH1_YEAST | GSH1 | genetic | 21623372 | |
| DHOM_YEAST | HOM6 | genetic | 21623372 | |
| PHO84_YEAST | PHO84 | genetic | 21623372 | |
| GCSH_YEAST | GCV3 | genetic | 21623372 | |
| PHSG_YEAST | GPH1 | genetic | 21623372 | |
| PYRC_YEAST | URA4 | genetic | 21623372 | |
| GAS1_YEAST | GAS1 | genetic | 23891562 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
