| UniProt ID | PYRC_YEAST | |
|---|---|---|
| UniProt AC | P20051 | |
| Protein Name | Dihydroorotase | |
| Gene Name | URA4 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 364 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MVQEIDLGLTCDMHVHVREGAMCELVTPKIRDGGVSIAYIMPNLQPPITTLDRVIEYKKTLQKLAPKTTFLMSFYLSKDLTPDLIHEAAQQHAIRGVKCYPAGVTTNSAAGVDPNDFSAFYPIFKAMQEENLVLNLHGEKPSVHDGDKEPIHVLNAEEAFLPALKKLHNDFPNLKIILEHCTSESAIKTIEDINKNVKKATDVKVAATLTAHHLFLTIDDWAGNPVNFCKPVAKLPNDKKALVKAAVSGKPYFFFGSDSAPHPVQNKANYEGVCAGVYSQSFAIPYIAQVFEEQNALENLKGFVSDFGISFYEVKDSEVASSDKAILFKKEQVIPQVISDGKDISIIPFKAGDKLSWSVRWEPR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 98 | N6-carboxylysine | QHAIRGVKCYPAGVT HHCCCCCEEEECCCC | 30.76 | - | |
| 98 | Ubiquitination | QHAIRGVKCYPAGVT HHCCCCCEEEECCCC | 30.76 | 24961812 | |
| 98 | Carboxylation | QHAIRGVKCYPAGVT HHCCCCCEEEECCCC | 30.76 | - | |
| 148 | Acetylation | PSVHDGDKEPIHVLN CCCCCCCCCCEEEEC | 71.56 | 24489116 | |
| 195 | Acetylation | KTIEDINKNVKKATD HHHHHHHHHCHHHHC | 64.55 | 22865919 | |
| 250 | Acetylation | VKAAVSGKPYFFFGS HHHHHCCCCEEEECC | 29.10 | 24489116 | |
| 257 | Phosphorylation | KPYFFFGSDSAPHPV CCEEEECCCCCCCCC | 24.20 | 28889911 | |
| 259 | Phosphorylation | YFFFGSDSAPHPVQN EEEECCCCCCCCCCC | 45.45 | 28889911 | |
| 324 | Acetylation | SEVASSDKAILFKKE HHHCCCCCEEEEEHH | 39.00 | 24489116 | |
| 342 | Acetylation | PQVISDGKDISIIPF CEECCCCCEEEEEEE | 57.80 | 24489116 | |
| 354 | Acetylation | IPFKAGDKLSWSVRW EEECCCCCEEEEEEE | 43.43 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PYRC_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PYRC_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PYRC_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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