DYR_YEAST - dbPTM
DYR_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DYR_YEAST
UniProt AC P07807
Protein Name Dihydrofolate reductase
Gene Name DFR1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 211
Subcellular Localization
Protein Description Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)..
Protein Sequence MAGGKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESNFKEHLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYCFEFTLYNRK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of DYR_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DYR_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DYR_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DYR_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CAPZA_YEASTCAP1physical
16554755
TIM23_YEASTTIM23physical
17959826
ATG8_YEASTATG8genetic
20093466
BEM1_YEASTBEM1genetic
20093466
VPS41_YEASTVPS41genetic
20093466
IES5_YEASTIES5genetic
20093466
RIM15_YEASTRIM15genetic
20093466
MSH4_YEASTMSH4genetic
20093466
ATG1_YEASTATG1genetic
20093466
XRN1_YEASTXRN1genetic
20093466
MED5_YEASTNUT1genetic
20093466
MON1_YEASTMON1genetic
20093466
YGI1_YEASTYGL081Wgenetic
20093466
YG34_YEASTYGR122Wgenetic
20093466
OPI1_YEASTOPI1genetic
20093466
HTD2_YEASTHTD2genetic
20093466
THIK_YEASTPOT1genetic
20093466
VPS55_YEASTVPS55genetic
20093466
ELF1_YEASTELF1genetic
20093466
METW_YEASTYLL058Wgenetic
20093466
UBI4P_YEASTUBI4genetic
20093466
RS30A_YEASTRPS30Agenetic
20093466
RS30B_YEASTRPS30Agenetic
20093466
VRP1_YEASTVRP1genetic
20093466
YPT7_YEASTYPT7genetic
20093466
AIM34_YEASTAIM34genetic
20093466
SAM37_YEASTSAM37genetic
20093466
NST1_YEASTNST1genetic
20093466
ATG3_YEASTATG3genetic
20093466
YN9A_YEASTYNR071Cgenetic
20093466
TRM11_YEASTTRM11genetic
20093466
MSN1_YEASTMSN1genetic
20093466
MSB4_YEASTMSB4genetic
20093466
VAM10_YEASTVAM10genetic
20093466
ATG13_YEASTATG13genetic
20093466
HSP79_YEASTSSE2physical
23530227
UBR1_YEASTUBR1physical
23530227
ATG1_YEASTATG1genetic
22282571
RIM15_YEASTRIM15genetic
22282571
BUD31_YEASTBUD31genetic
27708008
YCZ2_YEASTYCR102Cgenetic
27708008
RPN4_YEASTRPN4genetic
27708008
SAC3_YEASTSAC3genetic
27708008
MNN10_YEASTMNN10genetic
27708008
VAM7_YEASTVAM7genetic
27708008
PEF1_YEASTPEF1genetic
27708008
UBR1_YEASTUBR1genetic
27708008
SLT2_YEASTSLT2genetic
27708008
LPLA_YEASTAIM22genetic
27708008
YJE9_YEASTYJL049Wgenetic
27708008
RCY1_YEASTRCY1genetic
27708008
EF1G2_YEASTTEF4genetic
27708008
ERG3_YEASTERG3genetic
27708008
SIC1_YEASTSIC1genetic
27708008
ARP6_YEASTARP6genetic
27708008
ELP6_YEASTELP6genetic
27708008
EOS1_YEASTEOS1genetic
27708008
RAS2_YEASTRAS2genetic
27708008
PFD4_YEASTGIM3genetic
27708008
VPS27_YEASTVPS27genetic
27708008
BRE5_YEASTBRE5genetic
27708008
VPS21_YEASTVPS21genetic
27708008
VPS8_YEASTVPS8genetic
27708008
TPS1_YEASTTPS1genetic
27708008
AGP2_YEASTAGP2genetic
27708008
CLPX_YEASTMCX1genetic
27708008
CHK1_YEASTCHK1genetic
27708008
SGF29_YEASTSGF29genetic
27708008
MGR1_YEASTMGR1genetic
27708008
PAT1_YEASTPAT1genetic
27708008
GPR1_YEASTGPR1genetic
27708008
RLA1_YEASTRPP1Agenetic
27708008
PHO2_YEASTPHO2genetic
27708008
RAD57_YEASTRAD57genetic
27708008
RAD55_YEASTRAD55genetic
27708008
SWF1_YEASTSWF1genetic
27708008
ARO1_YEASTARO1genetic
27708008
NBP2_YEASTNBP2genetic
27708008
MET32_YEASTMET32genetic
27708008
ESC2_YEASTESC2genetic
27708008
XRS2_YEASTXRS2genetic
27708008
LSM6_YEASTLSM6genetic
27708008
PEX29_YEASTPEX29genetic
27708008
GET2_YEASTGET2genetic
27708008
RAD51_YEASTRAD51genetic
27708008
FAB1_YEASTFAB1genetic
27708008
YFJ0_YEASTYFR020Wgenetic
27708008
GET1_YEASTGET1genetic
27708008
KXD1_YEASTKXD1genetic
27708008
MRM2_YEASTMRM2genetic
27708008
AROC_YEASTARO2genetic
27708008
SUT1_YEASTSUT1genetic
27708008
RAD54_YEASTRAD54genetic
27708008
KIP3_YEASTKIP3genetic
27708008
SLX9_YEASTSLX9genetic
27708008
YG3L_YEASTYGR149Wgenetic
27708008
GTR2_YEASTGTR2genetic
27708008
TNA1_YEASTTNA1genetic
27708008
AIM17_YEASTAIM17genetic
27708008
SNF6_YEASTSNF6genetic
27708008
OCA5_YEASTOCA5genetic
27708008
TOM71_YEASTTOM71genetic
27708008
SS100_YEASTSPS100genetic
27708008
CRP1_YEASTCRP1genetic
27708008
EFM4_YEASTEFM4genetic
27708008
YIH7_YEASTYIL077Cgenetic
27708008
PRK1_YEASTPRK1genetic
27708008
ESL1_YEASTESL1genetic
27708008
VPS53_YEASTVPS53genetic
27708008
YJK7_YEASTYJL107Cgenetic
27708008
PYR1_YEASTURA2genetic
27708008
YJ24_YEASTKCH1genetic
27708008
PTK2_YEASTPTK2genetic
27708008
EMC2_YEASTEMC2genetic
27708008
MUD2_YEASTMUD2genetic
27708008
APN1_YEASTAPN1genetic
27708008
VPS51_YEASTVPS51genetic
27708008
BAS1_YEASTBAS1genetic
27708008
RNP1_YEASTRNP1genetic
27708008
PPR1_YEASTPPR1genetic
27708008
BRE2_YEASTBRE2genetic
27708008
RIC1_YEASTRIC1genetic
27708008
TRX1_YEASTTRX1genetic
27708008
GLYC_YEASTSHM2genetic
27708008
ORN_YEASTREX2genetic
27708008
AVL9_YEASTAVL9genetic
27708008
ACE2_YEASTACE2genetic
27708008
TOP3_YEASTTOP3genetic
27708008
ARV1_YEASTARV1genetic
27708008
YPT6_YEASTYPT6genetic
27708008
VRP1_YEASTVRP1genetic
27708008
PYRC_YEASTURA4genetic
27708008
UNG_YEASTUNG1genetic
27708008
RAD52_YEASTRAD52genetic
27708008
AIM32_YEASTAIM32genetic
27708008
SKY1_YEASTSKY1genetic
27708008
YM87_YEASTYMR253Cgenetic
27708008
YM8M_YEASTYMR279Cgenetic
27708008
YM96_YEASTYMR317Wgenetic
27708008
SFB2_YEASTSFB2genetic
27708008
OCA2_YEASTOCA2genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
PHO23_YEASTPHO23genetic
27708008
ADE_YEASTAAH1genetic
27708008
LSM7_YEASTLSM7genetic
27708008
INO4_YEASTINO4genetic
27708008
MSB4_YEASTMSB4genetic
27708008
HPF1_YEASTHPF1genetic
27708008
ENB1_YEASTENB1genetic
27708008
IAH1_YEASTIAH1genetic
27708008
VPS17_YEASTVPS17genetic
27708008
RMI1_YEASTRMI1genetic
27708008
NHP6A_YEASTNHP6Agenetic
27708008
AXL1_YEASTAXL1genetic
27708008
NAM7_YEASTNAM7genetic
27811238

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DYR_YEAST

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Related Literatures of Post-Translational Modification

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