HSP79_YEAST - dbPTM
HSP79_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HSP79_YEAST
UniProt AC P32590
Protein Name Heat shock protein homolog SSE2
Gene Name SSE2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 693
Subcellular Localization
Protein Description Has a calcium-dependent calmodulin-binding activity..
Protein Sequence MSTPFGLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGPRNRYLGESGKTKQTSNVKNTVENLKRIIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQEETKSSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIGLVDIGHSTYTCSIMAFRKGEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAYNRILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAKLTVNDIDFVEIIGGTTRIPVLKKSISDVFGKPLSSTLNQDEAVAKGAAFICAIHSPTLRVRPFKFEDIDPYSVSYTWDKQVDDEDRLEVFPANSSYPSTKLITLHRTGDFSMKAVYTHPSKLPKGTSTTIAKWSFTGVKVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLPEDAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALEEYIYTLRAKLDDEYSDFASDAEKEKLKNMLATTENWLYGDGDDSTKAKYIAKYEELASLGNIIRGRYLAKEEEKRQALRANQETSKMNDIAEKLAEQRRARAASDDSDDNNDENMDLD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSTPFGLDL
------CCCCCCEEC		44.8028152593
3Phosphorylation-----MSTPFGLDLG
-----CCCCCCEECC		22.7228152593
35PhosphorylationVNEVSNRSTPSLVGF
EEECCCCCCCCCCCC		49.2527214570
75AcetylationLKRIIGLKFKDPEFD
HHHHHCCEECCCCCC		45.1924489116
77AcetylationRIIGLKFKDPEFDIE
HHHCCEECCCCCCCC		71.4424489116
86AcetylationPEFDIENKFFTSKLV
CCCCCCCCCEEEEEE		29.1224489116
91AcetylationENKFFTSKLVQLKNG
CCCCEEEEEEECCCC		50.0124489116
226PhosphorylationGEMKVLGTAYDKHFG
CCEEEEEEECCCCCC		20.2030377154
230AcetylationVLGTAYDKHFGGRDF
EEEEECCCCCCCCCH		28.3224489116
250AcetylationEHFADQFKDKYKIDI
HHHHHHCCHHCCCCC		47.9124489116
273AcetylationRILIAAEKLKKVLSA
HHHHHHHHHHHHHCC		61.9624489116
355PhosphorylationPVLKKSISDVFGKPL
EHHHHHHHHHHCCCH		34.5128889911
384PhosphorylationAFICAIHSPTLRVRP
HEEEEECCCCEEECC		17.2922369663
386PhosphorylationICAIHSPTLRVRPFK
EEEECCCCEEECCCC		30.1522369663
432PhosphorylationYPSTKLITLHRTGDF
CCCCEEEEEEECCCC		27.2724961812
436PhosphorylationKLITLHRTGDFSMKA
EEEEEEECCCCCEEE		30.2921440633
440PhosphorylationLHRTGDFSMKAVYTH
EEECCCCCEEEEEEC		24.9024961812
442AcetylationRTGDFSMKAVYTHPS
ECCCCCEEEEEECCC		33.2424489116
449PhosphorylationKAVYTHPSKLPKGTS
EEEEECCCCCCCCCC		38.9428889911
455PhosphorylationPSKLPKGTSTTIAKW
CCCCCCCCCCEEEEE		29.0921126336
471AcetylationFTGVKVPKDQDFIPV
EECEECCCCCCCEEE		71.6424489116
584AcetylationYIYTLRAKLDDEYSD
HHHHHHHHCCHHHCC		46.1224489116
600AcetylationASDAEKEKLKNMLAT
CCHHHHHHHHHHHHH		75.6824489116
623UbiquitinationGDDSTKAKYIAKYEE
CCCCHHHHHHHCHHH		38.4522817900
627UbiquitinationTKAKYIAKYEELASL
HHHHHHHCHHHHHHC		43.5724961812
633PhosphorylationAKYEELASLGNIIRG
HCHHHHHHCHHHHHH		49.8130377154
642PhosphorylationGNIIRGRYLAKEEEK
HHHHHHHHHCCHHHH		17.5222369663
645AcetylationIRGRYLAKEEEKRQA
HHHHHHCCHHHHHHH		64.1625381059
661UbiquitinationRANQETSKMNDIAEK
HHHHHHHHHHHHHHH		49.4923749301
668UbiquitinationKMNDIAEKLAEQRRA
HHHHHHHHHHHHHHH		43.9323749301
668AcetylationKMNDIAEKLAEQRRA
HHHHHHHHHHHHHHH		43.9324489116
679PhosphorylationQRRARAASDDSDDNN
HHHHHHCCCCCCCCC		40.7519823750
682PhosphorylationARAASDDSDDNNDEN
HHHCCCCCCCCCCCC		52.4319823750
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HSP79_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HSP79_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HSP79_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CLH_YEASTCHC1physical
11805826
HSP42_YEASTHSP42physical
16554755
SSB2_YEASTSSB2physical
16554755
HRR25_YEASTHRR25physical
18467557
LSP1_YEASTLSP1physical
18467557
MTR4_YEASTMTR4physical
19536198
ECM5_YEASTECM5physical
19536198
HRD1_YEASTHRD1physical
19536198
HSP71_YEASTSSA1physical
19536198
SSB1_YEASTSSB1physical
19536198
SSB2_YEASTSSB2physical
19536198
HSP7F_YEASTSSE1physical
19536198
HSP42_YEASTHSP42physical
19536198
HEL2_YEASTHEL2genetic
20093466
MSH4_YEASTMSH4genetic
20093466
MON1_YEASTMON1genetic
20093466
MUP1_YEASTMUP1genetic
20093466
YL422_YEASTYLR422Wgenetic
20093466
YPT7_YEASTYPT7genetic
20093466
NST1_YEASTNST1genetic
20093466
NTH2_YEASTNTG2genetic
20093466
YVC1_YEASTYVC1genetic
20093466
HSP7F_YEASTSSE1genetic
20093466
TBP6_YEASTYTA6genetic
20093466
YME1_YEASTYME1genetic
20093466
FES1_YEASTFES1genetic
18335038
SNL1_YEASTSNL1genetic
18335038
EF3A_YEASTYEF3physical
20237159
CDC48_YEASTCDC48physical
20237159
HSP82_YEASTHSP82physical
20237159
HSC82_YEASTHSC82physical
20237159
STI1_YEASTSTI1physical
20237159
HSP71_YEASTSSA1physical
20237159
HSP72_YEASTSSA2physical
20237159
SSB1_YEASTSSB1physical
20237159
SSB2_YEASTSSB2physical
20237159
MAS5_YEASTYDJ1physical
20237159
SSB1_YEASTSSB1physical
22635919
HSP71_YEASTSSA1physical
22635919
HSP72_YEASTSSA2physical
22635919
SWI6_YEASTSWI6genetic
27708008
CND2_YEASTBRN1genetic
27708008
PRP9_YEASTPRP9genetic
27708008
CDC4_YEASTCDC4genetic
27708008
CFT2_YEASTCFT2genetic
27708008
SEC22_YEASTSEC22genetic
27708008
TAD3_YEASTTAD3genetic
27708008
RNA1_YEASTRNA1genetic
27708008
SGT1_YEASTSGT1genetic
27708008
PSB5_YEASTPRE2genetic
27708008
TPS2_YEASTTPS2genetic
27708008
ARO1_YEASTARO1genetic
27708008
HEL2_YEASTHEL2genetic
27708008
MSH4_YEASTMSH4genetic
27708008
MON1_YEASTMON1genetic
27708008
ATG1_YEASTATG1genetic
27708008
MUP1_YEASTMUP1genetic
27708008
PSA3_YEASTPRE9genetic
27708008
GTR2_YEASTGTR2genetic
27708008
THIK_YEASTPOT1genetic
27708008
VPS35_YEASTVPS35genetic
27708008
FABG_YEASTOAR1genetic
27708008
YPT7_YEASTYPT7genetic
27708008
KAR5_YEASTKAR5genetic
27708008
YM8F_YEASTYMR265Cgenetic
27708008
OCA2_YEASTOCA2genetic
27708008
LSM7_YEASTLSM7genetic
27708008
NTH2_YEASTNTG2genetic
27708008
VPS68_YEASTVPS68genetic
27708008
YVC1_YEASTYVC1genetic
27708008
IDH2_YEASTIDH2genetic
27708008
PMA2_YEASTPMA2genetic
27708008
TBP6_YEASTYTA6genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
CHMU_YEASTARO7genetic
27708008
FES1_YEASTFES1genetic
29507114
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HSP79_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-384 AND THR-386, ANDMASS SPECTROMETRY.
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae.";
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.;
J. Proteome Res. 6:1190-1197(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-384, AND MASSSPECTROMETRY.
"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway.";
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.;
Mol. Cell. Proteomics 4:310-327(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-384, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory