| UniProt ID | FAB1_YEAST | |
|---|---|---|
| UniProt AC | P34756 | |
| Protein Name | 1-phosphatidylinositol 3-phosphate 5-kinase FAB1 | |
| Gene Name | FAB1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 2278 | |
| Subcellular Localization |
Vacuole membrane Peripheral membrane protein. Endosome membrane Peripheral membrane protein. Localization to the vacuole membrane requires VAC14 and FIG4. |
|
| Protein Description | The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. The product of the reaction it catalyzes functions as an important regulator of vacuole homeostasis perhaps by controlling membrane flux to and/or from the vacuole. Hyperosmotic shock-induced increase in the levels of PtdIns(3,5)P2 requires the presence of VAC7, VAC14, and/or FIG4.. | |
| Protein Sequence | MSSEEPHASISFPDGSHVRSSSTGTSSVNTIDATLSRPNYIKKPSLHIMSTSTTSTTTDLVTNPILSNISVPKISPPTSSSIATATSTSHVTGTASHSNIKANANTSTSVNKKNLPPTTSGRIPSSTIKRYPSRYKPSHSLQLPIKNDSNFKRSSIYASKSTVTAIPIRNNRPISMQNSYARTPDSDHDDVGDEVSSIKSASSSLTASLSKSFLFAFYNNRKKDKTSNNGVLSKEYWMKDESSKECFSCGKTFNTFRRKHHCRICGQIFCSSCTLLIDGDRFGCHAKMRVCYNCYEHADTYEDSSDEENDSTMQLNEPRSRSRSRSSNTNPYSHSHSHLHLISQDNHNGTDLHDPVAATDNPQQQNEVYLLNDDDVQSIMTSGEDSKLFISTPPPPPKMAIPATKQGGSLEISFDSENDRALHYQDDNPGRHHHLDSVPTRYTIRDMDNISHYDTNSNSTLRPHYNTNNSTITINNLNNTTSNNSNYNNTNSNSNINNPAHSLRRSIFHYVSSNSVNKDSNNSSATPASSAQSSSILDPANRIIGNYAHRNYKFKFNYNSKGPSQQNDTANGNNDNNNNNNNNNNNNNNNSASGIADNNNIPSNDNGTTFTLDKKKRNPLTKSKSTSAYLEYPLNEEDSSEDEGSMSIYSVLNDDHKTDNPIRSMRNSTKSFQRAQASLQRMRFRRKSKSKHFPNNSKSSIYRDLNFLTNSTPNLLSVVSDDNLYDDSSPLQDKASSSAASRLTDRKFSNSSGSNNNSNSNSNINTDPWKRIASISGFKLKKEKKRELNEVSLLHMHALLKQLLNDQEISNLQEWITLLDGALRKVLRTILNARDLNTLDFRQTYVKIKRISGGSPQNSEYIDGVVFSKALPSKTMPRHLKNPRILLIMFPLEYQKNNNHFLSIESVFRQEREYLDKLVSRLKSLHPDIIYVGANVSGYALELLNDSGIVVQFNMKPQVIERIAKLTEADIAISVDKLATNIKMGECETFEVKSYIYGNISKTYTFLRGCNPELGGTILLRGDSLENLRKIKQVSEFMVYAIFSLKLESSFFNDNFIQLSTDVYLKRAESKKLQVFEGYFADFLIKFNNRILTVSPTVDFPIPFLLEKARGLEKKLIERINQYESESDLDRQTQLNMLQGLESTITKKHLGNLIKFLHEMEIENLELEFQKRSRQWEVSYSSSQNLLGTGSHQSITVLYSMVSTKTATPCVGPQIVTIDYFWDSDISIGQFIENVVGTARYPCQQGCNGLYLDHYRSYVHGSGKVDVLIEKFQTRLPKLKDIILTWSYCKKCGTSTPILQISEKTWNHSFGKYLEVMFWSYKDSVTGIGKCPHDFTKDHVKYFGYNDLVVRLEYSDLEVHELITPPRKIKWKPHIDIKLKVELYYKILEKINNFYGSVLSRLERIKLDSMTKDKVLSGQAKIIELKSNATEEQKLMLQDLDTFYADSPCDQHLPLNLVIKSLYDKAVNWNSTFAIFAKSYLPSETDISRITAKQLKKLFYDSSRKDSEDKKSLHDEKAKTRKPEKNELPLEGLKDVEKPKIDSKNTTENRDRTNEPQNAVTITTFKDDTPIIPTSGTSHLTVTPSASSVSSSLTPQTEERPPISRSGTGISMTHDKSTRPNIRKMSSDSSLCGLASLANEYSKNNKVSKLATFFDQMHFDALSKEFELERERERLQLNKDKYQAIRLQTSTPIVEIYKNVKDAVDEPLHSRSSGNNLSSANVKTLEAPVGEHSRANNCNPPNLDQNLETELENSISQWGENILNPSGKTTASTHLNSKPVVKETSENPKSIVRESDNSKSEPLPPVITTTTVNKVESTPQPEKSLLMKTLSNFWADRSAYLWKPLVYPTCPSEHIFTDSDVIIREDEPSSLIAFCLSTSDYRNKMMNLNVQQQQQQQTAEAAPAKTGGNSGGTTQTGDPSVNISPSVSTTSHNKGRDSEISSLVTTKEGLLNTPPIEGARDRTPQESQTHSQANLDTLQELEKIMTKKTATHLRYQFEEGLTVMSCKIFFTEHFDVFRKICDCQENFIQSLSRCVKWDSNGGKSGSGFLKTLDDRFIIKELSHAELEAFIKFAPSYFEYMAQAMFHDLPTTLAKVFGFYQIQVKSSISSSKSYKMDVIIMENLFYEKKTTRIFDLKGSMRNRHVEQTGKANEVLLDENMVEYIYESPIHVREYDKKLLRASVWNDTLFLAKMNVMDYSLVIGIDNEGYTLTVGIIDFIRTFTWDKKLESWVKEKGLVGGASVIKQPTVVTPRQYKKRFREAMERYILMVPDPWYREGN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MSSEEPHAS ------CCCCCCCCE | 58.73 | 22814378 | |
| 2 | Phosphorylation | ------MSSEEPHAS ------CCCCCCCCE | 58.73 | 30377154 | |
| 3 | Phosphorylation | -----MSSEEPHASI -----CCCCCCCCEE | 58.81 | 30377154 | |
| 9 | Phosphorylation | SSEEPHASISFPDGS CCCCCCCEEECCCCC | 18.74 | 30377154 | |
| 11 | Phosphorylation | EEPHASISFPDGSHV CCCCCEEECCCCCCC | 28.38 | 30377154 | |
| 16 | Phosphorylation | SISFPDGSHVRSSST EEECCCCCCCCCCCC | 26.62 | 30377154 | |
| 20 | Phosphorylation | PDGSHVRSSSTGTSS CCCCCCCCCCCCCCC | 27.79 | 22369663 | |
| 21 | Phosphorylation | DGSHVRSSSTGTSSV CCCCCCCCCCCCCCC | 22.73 | 22369663 | |
| 22 | Phosphorylation | GSHVRSSSTGTSSVN CCCCCCCCCCCCCCE | 31.91 | 22369663 | |
| 23 | Phosphorylation | SHVRSSSTGTSSVNT CCCCCCCCCCCCCEE | 46.56 | 22369663 | |
| 25 | Phosphorylation | VRSSSTGTSSVNTID CCCCCCCCCCCEEEE | 20.23 | 22369663 | |
| 26 | Phosphorylation | RSSSTGTSSVNTIDA CCCCCCCCCCEEEEE | 33.36 | 22369663 | |
| 27 | Phosphorylation | SSSTGTSSVNTIDAT CCCCCCCCCEEEEEE | 21.15 | 22369663 | |
| 30 | Phosphorylation | TGTSSVNTIDATLSR CCCCCCEEEEEECCC | 20.34 | 22369663 | |
| 34 | Phosphorylation | SVNTIDATLSRPNYI CCEEEEEECCCCCCC | 22.86 | 29734811 | |
| 36 | Phosphorylation | NTIDATLSRPNYIKK EEEEEECCCCCCCCC | 41.14 | 22369663 | |
| 40 | Phosphorylation | ATLSRPNYIKKPSLH EECCCCCCCCCCEEE | 19.46 | 22369663 | |
| 125 | Phosphorylation | TTSGRIPSSTIKRYP CCCCCCCHHHHCCCC | 37.43 | 30377154 | |
| 164 | Phosphorylation | YASKSTVTAIPIRNN EEECCEEEEEECCCC | 20.96 | 24961812 | |
| 175 | Phosphorylation | IRNNRPISMQNSYAR CCCCCCCCCCCCCCC | 19.59 | 24961812 | |
| 179 | Phosphorylation | RPISMQNSYARTPDS CCCCCCCCCCCCCCC | 11.86 | 24961812 | |
| 180 | Phosphorylation | PISMQNSYARTPDSD CCCCCCCCCCCCCCC | 13.98 | 24961812 | |
| 183 | Phosphorylation | MQNSYARTPDSDHDD CCCCCCCCCCCCCCC | 24.23 | 20377248 | |
| 186 | Phosphorylation | SYARTPDSDHDDVGD CCCCCCCCCCCCCCH | 37.74 | 22369663 | |
| 196 | Phosphorylation | DDVGDEVSSIKSASS CCCCHHHHHHHHHCH | 25.05 | 24961812 | |
| 197 | Phosphorylation | DVGDEVSSIKSASSS CCCHHHHHHHHHCHH | 38.93 | 21440633 | |
| 200 | Phosphorylation | DEVSSIKSASSSLTA HHHHHHHHHCHHHHH | 31.54 | 22369663 | |
| 202 | Phosphorylation | VSSIKSASSSLTASL HHHHHHHCHHHHHHH | 27.79 | 22369663 | |
| 203 | Phosphorylation | SSIKSASSSLTASLS HHHHHHCHHHHHHHC | 29.14 | 22369663 | |
| 204 | Phosphorylation | SIKSASSSLTASLSK HHHHHCHHHHHHHCH | 27.52 | 20377248 | |
| 206 | Phosphorylation | KSASSSLTASLSKSF HHHCHHHHHHHCHHH | 19.02 | 21440633 | |
| 208 | Phosphorylation | ASSSLTASLSKSFLF HCHHHHHHHCHHHHH | 28.13 | 21551504 | |
| 210 | Phosphorylation | SSLTASLSKSFLFAF HHHHHHHCHHHHHHH | 24.61 | 19823750 | |
| 212 | Phosphorylation | LTASLSKSFLFAFYN HHHHHCHHHHHHHHC | 24.65 | 24961812 | |
| 227 | Phosphorylation | NRKKDKTSNNGVLSK CCCCCCCCCCCCCCH | 33.76 | 19779198 | |
| 233 | Phosphorylation | TSNNGVLSKEYWMKD CCCCCCCCHHHHCCC | 22.49 | 19779198 | |
| 295 | Phosphorylation | MRVCYNCYEHADTYE EEEECCCCCCCCCCC | 13.70 | 19779198 | |
| 300 | Phosphorylation | NCYEHADTYEDSSDE CCCCCCCCCCCCCCC | 29.60 | 19779198 | |
| 301 | Phosphorylation | CYEHADTYEDSSDEE CCCCCCCCCCCCCCC | 20.49 | 19779198 | |
| 304 | Phosphorylation | HADTYEDSSDEENDS CCCCCCCCCCCCCCC | 27.96 | 23749301 | |
| 305 | Phosphorylation | ADTYEDSSDEENDST CCCCCCCCCCCCCCC | 62.45 | 23749301 | |
| 311 | Phosphorylation | SSDEENDSTMQLNEP CCCCCCCCCCCCCCC | 37.04 | 19779198 | |
| 312 | Phosphorylation | SDEENDSTMQLNEPR CCCCCCCCCCCCCCC | 16.29 | 19779198 | |
| 391 | Phosphorylation | EDSKLFISTPPPPPK CCCCEEECCCCCCCC | 27.77 | 29136822 | |
| 392 | Phosphorylation | DSKLFISTPPPPPKM CCCEEECCCCCCCCC | 34.69 | 19823750 | |
| 506 | Phosphorylation | PAHSLRRSIFHYVSS HHHHHHHHHHHHHHC | 24.15 | 23749301 | |
| 510 | Phosphorylation | LRRSIFHYVSSNSVN HHHHHHHHHHCCCCC | 7.41 | 22369663 | |
| 512 | Phosphorylation | RSIFHYVSSNSVNKD HHHHHHHHCCCCCCC | 19.35 | 22369663 | |
| 513 | Phosphorylation | SIFHYVSSNSVNKDS HHHHHHHCCCCCCCC | 24.07 | 22369663 | |
| 515 | Phosphorylation | FHYVSSNSVNKDSNN HHHHHCCCCCCCCCC | 29.08 | 22369663 | |
| 625 | Phosphorylation | NPLTKSKSTSAYLEY CCCCCCCCCHHEEEE | 34.38 | 19823750 | |
| 626 | Phosphorylation | PLTKSKSTSAYLEYP CCCCCCCCHHEEEEC | 22.55 | 19823750 | |
| 627 | Phosphorylation | LTKSKSTSAYLEYPL CCCCCCCHHEEEECC | 23.23 | 19823750 | |
| 629 | Phosphorylation | KSKSTSAYLEYPLNE CCCCCHHEEEECCCC | 10.38 | 19823750 | |
| 632 | Phosphorylation | STSAYLEYPLNEEDS CCHHEEEECCCCCCC | 15.49 | 19823750 | |
| 639 | Phosphorylation | YPLNEEDSSEDEGSM ECCCCCCCCCCCCCC | 38.62 | 19795423 | |
| 640 | Phosphorylation | PLNEEDSSEDEGSMS CCCCCCCCCCCCCCC | 62.48 | 19795423 | |
| 645 | Phosphorylation | DSSEDEGSMSIYSVL CCCCCCCCCCHHHHH | 13.81 | 24961812 | |
| 647 | Phosphorylation | SEDEGSMSIYSVLND CCCCCCCCHHHHHCC | 21.77 | 24961812 | |
| 649 | Phosphorylation | DEGSMSIYSVLNDDH CCCCCCHHHHHCCCC | 5.85 | 19823750 | |
| 650 | Phosphorylation | EGSMSIYSVLNDDHK CCCCCHHHHHCCCCC | 20.61 | 19823750 | |
| 668 | Phosphorylation | PIRSMRNSTKSFQRA CHHHHHHHHHHHHHH | 27.18 | 28889911 | |
| 669 | Phosphorylation | IRSMRNSTKSFQRAQ HHHHHHHHHHHHHHH | 33.97 | 28889911 | |
| 720 | Phosphorylation | PNLLSVVSDDNLYDD CCEEEECCCCCCCCC | 36.77 | 28889911 | |
| 736 | Phosphorylation | SPLQDKASSSAASRL CCCCHHHCHHHHHHH | 30.48 | 24961812 | |
| 737 | Phosphorylation | PLQDKASSSAASRLT CCCHHHCHHHHHHHH | 28.93 | 21440633 | |
| 738 | Phosphorylation | LQDKASSSAASRLTD CCHHHCHHHHHHHHC | 25.92 | 21440633 | |
| 741 | Phosphorylation | KASSSAASRLTDRKF HHCHHHHHHHHCCCC | 27.78 | 24961812 | |
| 744 | Phosphorylation | SSAASRLTDRKFSNS HHHHHHHHCCCCCCC | 32.42 | 24961812 | |
| 749 | Phosphorylation | RLTDRKFSNSSGSNN HHHCCCCCCCCCCCC | 38.55 | 23749301 | |
| 751 | Phosphorylation | TDRKFSNSSGSNNNS HCCCCCCCCCCCCCC | 34.57 | 23749301 | |
| 752 | Phosphorylation | DRKFSNSSGSNNNSN CCCCCCCCCCCCCCC | 50.95 | 21440633 | |
| 754 | Phosphorylation | KFSNSSGSNNNSNSN CCCCCCCCCCCCCCC | 38.03 | 21440633 | |
| 758 | Phosphorylation | SSGSNNNSNSNSNIN CCCCCCCCCCCCCCC | 43.70 | 28889911 | |
| 760 | Phosphorylation | GSNNNSNSNSNINTD CCCCCCCCCCCCCCC | 41.26 | 28889911 | |
| 774 | Phosphorylation | DPWKRIASISGFKLK CHHHHHHHHHCCCCC | 18.21 | 21440633 | |
| 776 | Phosphorylation | WKRIASISGFKLKKE HHHHHHHHCCCCCHH | 35.36 | 21551504 | |
| 1049 | Phosphorylation | IFSLKLESSFFNDNF HHHCHHHHHHCCCCE | 42.77 | 19779198 | |
| 1064 | Phosphorylation | IQLSTDVYLKRAESK EEEHHHEHHHHHHHC | 14.87 | 19779198 | |
| 1133 | Phosphorylation | ESDLDRQTQLNMLQG CCHHHHHHHHHHHHH | 35.60 | 28132839 | |
| 1262 | Phosphorylation | YRSYVHGSGKVDVLI HHHHCCCCCCHHHHH | 22.14 | 28889911 | |
| 1295 | Phosphorylation | YCKKCGTSTPILQIS HHHHHCCCCCEEEEE | 19.92 | 27017623 | |
| 1296 | Phosphorylation | CKKCGTSTPILQISE HHHHCCCCCEEEEEH | 17.74 | 27017623 | |
| 1397 | Phosphorylation | KINNFYGSVLSRLER HHHHHHHHHHHHHHH | 14.43 | 28889911 | |
| 1400 | Phosphorylation | NFYGSVLSRLERIKL HHHHHHHHHHHHCCC | 32.44 | 28889911 | |
| 1479 | Phosphorylation | TFAIFAKSYLPSETD HHHHHHHHHCCCCCC | 28.59 | 28889911 | |
| 1480 | Phosphorylation | FAIFAKSYLPSETDI HHHHHHHHCCCCCCH | 23.17 | 28889911 | |
| 1483 | Phosphorylation | FAKSYLPSETDISRI HHHHHCCCCCCHHHH | 51.00 | 28889911 | |
| 1606 | Phosphorylation | ERPPISRSGTGISMT CCCCCCCCCCCCCCC | 33.64 | 22369663 | |
| 1608 | Phosphorylation | PPISRSGTGISMTHD CCCCCCCCCCCCCCC | 32.37 | 22369663 | |
| 1611 | Phosphorylation | SRSGTGISMTHDKST CCCCCCCCCCCCCCC | 20.97 | 22369663 | |
| 1613 | Phosphorylation | SGTGISMTHDKSTRP CCCCCCCCCCCCCCC | 21.82 | 22369663 | |
| 1617 | Phosphorylation | ISMTHDKSTRPNIRK CCCCCCCCCCCCCHH | 35.39 | 19823750 | |
| 1618 | Phosphorylation | SMTHDKSTRPNIRKM CCCCCCCCCCCCHHC | 56.75 | 19823750 | |
| 1626 | Phosphorylation | RPNIRKMSSDSSLCG CCCCHHCCCCCCHHH | 33.75 | 23749301 | |
| 1627 | Phosphorylation | PNIRKMSSDSSLCGL CCCHHCCCCCCHHHH | 37.70 | 20377248 | |
| 1629 | Phosphorylation | IRKMSSDSSLCGLAS CHHCCCCCCHHHHHH | 27.45 | 21440633 | |
| 1630 | Phosphorylation | RKMSSDSSLCGLASL HHCCCCCCHHHHHHH | 32.44 | 20377248 | |
| 1636 | Phosphorylation | SSLCGLASLANEYSK CCHHHHHHHHHHHHC | 32.81 | 19823750 | |
| 1641 | Phosphorylation | LASLANEYSKNNKVS HHHHHHHHHCCCCHH | 25.42 | 19823750 | |
| 1642 | Phosphorylation | ASLANEYSKNNKVSK HHHHHHHHCCCCHHH | 23.80 | 19823750 | |
| 1648 | Phosphorylation | YSKNNKVSKLATFFD HHCCCCHHHHHHHHH | 24.46 | 27017623 | |
| 1689 | Phosphorylation | YQAIRLQTSTPIVEI HHHHHHHCCCCHHHH | 38.88 | 29734811 | |
| 1691 | Phosphorylation | AIRLQTSTPIVEIYK HHHHHCCCCHHHHHH | 22.03 | 25752575 | |
| 1710 | Phosphorylation | AVDEPLHSRSSGNNL HCCCCCCCCCCCCCC | 41.35 | 20377248 | |
| 1712 | Phosphorylation | DEPLHSRSSGNNLSS CCCCCCCCCCCCCCC | 45.68 | 22369663 | |
| 1713 | Phosphorylation | EPLHSRSSGNNLSSA CCCCCCCCCCCCCCC | 44.42 | 22369663 | |
| 1718 | Phosphorylation | RSSGNNLSSANVKTL CCCCCCCCCCCCEEE | 29.54 | 22369663 | |
| 1719 | Phosphorylation | SSGNNLSSANVKTLE CCCCCCCCCCCEEEE | 27.33 | 22369663 | |
| 1772 | Phosphorylation | PSGKTTASTHLNSKP CCCCCCCCHHCCCCC | 17.80 | 21440633 | |
| 1916 | Phosphorylation | NSGGTTQTGDPSVNI CCCCCCCCCCCCCEE | 41.27 | 24961812 | |
| 1920 | Phosphorylation | TTQTGDPSVNISPSV CCCCCCCCCEECCCC | 32.32 | 24961812 | |
| 1924 | Phosphorylation | GDPSVNISPSVSTTS CCCCCEECCCCCCCC | 13.10 | 20377248 | |
| 1926 | Phosphorylation | PSVNISPSVSTTSHN CCCEECCCCCCCCCC | 23.16 | 24961812 | |
| 1928 | Phosphorylation | VNISPSVSTTSHNKG CEECCCCCCCCCCCC | 30.24 | 20377248 | |
| 1929 | Phosphorylation | NISPSVSTTSHNKGR EECCCCCCCCCCCCC | 30.11 | 21551504 | |
| 1930 | Phosphorylation | ISPSVSTTSHNKGRD ECCCCCCCCCCCCCC | 22.08 | 23749301 | |
| 1931 | Phosphorylation | SPSVSTTSHNKGRDS CCCCCCCCCCCCCCH | 25.75 | 20377248 | |
| 1938 | Phosphorylation | SHNKGRDSEISSLVT CCCCCCCHHHHHHEE | 35.15 | 22369663 | |
| 1941 | Phosphorylation | KGRDSEISSLVTTKE CCCCHHHHHHEECCC | 17.36 | 22369663 | |
| 1942 | Phosphorylation | GRDSEISSLVTTKEG CCCHHHHHHEECCCC | 32.30 | 22369663 | |
| 1945 | Phosphorylation | SEISSLVTTKEGLLN HHHHHHEECCCCCCC | 37.13 | 22369663 | |
| 1946 | Phosphorylation | EISSLVTTKEGLLNT HHHHHEECCCCCCCC | 21.44 | 22369663 | |
| 1953 | Phosphorylation | TKEGLLNTPPIEGAR CCCCCCCCCCCCCCC | 30.34 | 15665377 | |
| 1963 | Phosphorylation | IEGARDRTPQESQTH CCCCCCCCCCHHHHH | 33.34 | 23749301 | |
| 1967 | Phosphorylation | RDRTPQESQTHSQAN CCCCCCHHHHHHCCC | 34.82 | 19779198 | |
| 1971 | Phosphorylation | PQESQTHSQANLDTL CCHHHHHHCCCHHHH | 34.08 | 19779198 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FAB1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FAB1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FAB1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-22; SER-186; SER-202;THR-206; THR-392; SER-720; THR-1691; SER-1713 AND THR-1953, AND MASSSPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-186, AND MASSSPECTROMETRY. | |
| "Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway."; Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.; Mol. Cell. Proteomics 4:310-327(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-20; THR-392 ANDTHR-1953, AND MASS SPECTROMETRY. | |
