SFK1_YEAST - dbPTM
SFK1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SFK1_YEAST
UniProt AC P35735
Protein Name Protein SFK1
Gene Name SFK1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 353
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description May control the production of phosphatidylinositol 4-phosphate (PI4P) by the STT4 PI 4-kinase. Mediates proper localization of STT4 to the plasma membrane..
Protein Sequence MIQFKSPGNWLFIVPWIAFIPWYGMLIAMLICWASQGHPIYWFMHSEQFPVYISDIGATNLRPLFISCAGWQGLGYVITVALEFFQRSGYLPFQLKKKDPSISDSTSYAEKLHSGKYLMPPYYTKDERNLIFAAFVLGSIGELALLFSSIFSTALYHRVHIAMVSVFVVFMFLSTCCLIAEYFLMGRHYASVHPLASPHFNPQSSEKSFNQDYNTVDELPWYKWKGHVWNKFTISATLKVIWLTLAVVWAICFGAINDRSKSACFEWLLAFWFGIIFMILSADFYLGGRYRQSRYFNHVESFSGYYKYDKALGLYHSEDVLPSDDNAGVIATETASSNIYNNSSSNESIQVVV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
101PhosphorylationQLKKKDPSISDSTSY
EEECCCCCCCCCCCH		44.8721440633
105PhosphorylationKDPSISDSTSYAEKL
CCCCCCCCCCHHHHH		16.6827017623
106PhosphorylationDPSISDSTSYAEKLH
CCCCCCCCCHHHHHH		30.6527017623
107PhosphorylationPSISDSTSYAEKLHS
CCCCCCCCHHHHHHC		26.7123749301
108PhosphorylationSISDSTSYAEKLHSG
CCCCCCCHHHHHHCC		20.9025704821
124PhosphorylationYLMPPYYTKDERNLI
CCCCCCCCHHHHHHH		26.6127821475
204PhosphorylationSPHFNPQSSEKSFNQ
CCCCCCCCCCCCCCC		41.5429688323
205PhosphorylationPHFNPQSSEKSFNQD
CCCCCCCCCCCCCCC		43.7429688323
208PhosphorylationNPQSSEKSFNQDYNT
CCCCCCCCCCCCCCC		25.9422369663
213PhosphorylationEKSFNQDYNTVDELP
CCCCCCCCCCHHCCC		11.7221440633
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SFK1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SFK1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SFK1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
VDAC1_YEASTPOR1physical
12837385
STT4_YEASTSTT4physical
12015967
STT4_YEASTSTT4genetic
12015967
MID2_YEASTMID2physical
18467557
PDR5_YEASTPDR5physical
18467557
MSC3_YEASTMSC3physical
18467557
YL326_YEASTYLR326Wphysical
18467557
WSC2_YEASTWSC2physical
18467557
PPZ1_YEASTPPZ1physical
18467557
PDR12_YEASTPDR12physical
18467557
YL413_YEASTINA1physical
18467557
TCB3_YEASTTCB3physical
18467557
TPO3_YEASTTPO3physical
18467557
TPO1_YEASTTPO1physical
18467557
MEP3_YEASTMEP3physical
18467557
TPO4_YEASTTPO4physical
18467557
FLC1_YEASTFLC1physical
18467557
SFK1_YEASTSFK1physical
18467557
ARF3_YEASTARF3physical
18467557
IPYR_YEASTIPP1genetic
19269370
FAB1_YEASTFAB1genetic
19269370
PACC_YEASTRIM101genetic
20093466
REI1_YEASTREI1genetic
27708008
XRS2_YEASTXRS2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SFK1_YEAST

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Related Literatures of Post-Translational Modification

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