dbPTM

ARF3_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ARF3_YEAST
UniProt AC	P40994
Protein Name	ADP-ribosylation factor 3
Gene Name	ARF3
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	183
Subcellular Localization	Golgi apparatus.
Protein Description	GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus..
Protein Sequence	MGNSISKVLGKLFGSKEMKILMLGLDKAGKTTILYKLKLNKIKTSTPTVGFNVETVTYKNVKFNMWDVGGQQRLRPLWRHYFPATTALIFVIDSSARNRMEEAKEELYSIIGEKEMENVVLLVWANKQDLKDAMKPQEVSDFLELEKNLKNQPWCVIGSNALSGQGLVEGLSWISNNTNVPKK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGNSISKVL ------CCCHHHHHH	36.27	-
4	Phosphorylation	----MGNSISKVLGK ----CCCHHHHHHHH	23.62	19823750
6	Phosphorylation	--MGNSISKVLGKLF --CCCHHHHHHHHHH	19.28	19823750
36	Acetylation	GKTTILYKLKLNKIK CCEEEEEEEECCCCC	35.38	24489116
46	Phosphorylation	LNKIKTSTPTVGFNV CCCCCCCCCCCCEEE	28.36	27214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ARF3_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ARF3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ARF3_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PROF_YEAST	PFY1	genetic	14668359
BUD6_YEAST	BUD6	genetic	17425670
GEA2_YEAST	GEA2	genetic	17425670
BNI1_YEAST	BNI1	genetic	17425670
SYP1_YEAST	SYP1	genetic	17425670
RUD3_YEAST	RUD3	physical	15504911
AFI1_YEAST	AFI1	physical	18397879
YEL1_YEAST	YEL1	physical	18719252
GTS1_YEAST	GTS1	physical	18208507
ARF3_YEAST	ARF3	physical	18208507
YPT31_YEAST	YPT31	genetic	20526336
FIMB_YEAST	SAC6	genetic	20526336
BUD2_YEAST	BUD2	physical	23783029
RSR1_YEAST	RSR1	genetic	23783029
LSB5_YEAST	LSB5	physical	15651983
COG3_YEAST	COG3	genetic	27708008
ATG15_YEAST	ATG15	genetic	27708008
KPC1_YEAST	PKC1	genetic	27708008
GNA1_YEAST	GNA1	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
STS1_YEAST	STS1	genetic	27708008
UTP13_YEAST	UTP13	genetic	27708008
CDC25_YEAST	CDC25	genetic	27708008
RPN7_YEAST	RPN7	genetic	27708008
ATC3_YEAST	DRS2	genetic	27708008
ETR1_YEAST	ETR1	genetic	27708008
REI1_YEAST	REI1	genetic	27708008
STE50_YEAST	STE50	genetic	27708008
RS14A_YEAST	RPS14A	genetic	27708008
SLX5_YEAST	SLX5	genetic	27708008
UGA3_YEAST	UGA3	genetic	27708008
RRP8_YEAST	RRP8	genetic	27708008
INO2_YEAST	INO2	genetic	27708008
SAN1_YEAST	SAN1	genetic	27708008
H2A1_YEAST	HTA1	genetic	27708008
EMP47_YEAST	EMP47	genetic	27708008
HTD2_YEAST	HTD2	genetic	27708008
PDK1_YEAST	PKP1	genetic	27708008
SDHX_YEAST	YJL045W	genetic	27708008
EAF6_YEAST	EAF6	genetic	27708008
ILM1_YEAST	ILM1	genetic	27708008
ELM1_YEAST	ELM1	genetic	27708008
MDM35_YEAST	MDM35	genetic	27708008
PFD6_YEAST	YKE2	genetic	27708008
FRE1_YEAST	FRE1	genetic	27708008
COQ11_YEAST	YLR290C	genetic	27708008
CDA2_YEAST	CDA2	genetic	27708008
ROM2_YEAST	ROM2	genetic	27708008
VID22_YEAST	VID22	genetic	27708008
FMP42_YEAST	YMR221C	genetic	27708008
PFD4_YEAST	GIM3	genetic	27708008
PDE2_YEAST	PDE2	genetic	27708008
PMA2_YEAST	PMA2	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
COX10_YEAST	COX10	genetic	27708008
CISY3_YEAST	CIT3	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ARF3_YEAST

Related Literatures of Post-Translational Modification