| UniProt ID | SAN1_YEAST | |
|---|---|---|
| UniProt AC | P22470 | |
| Protein Name | Protein SAN1 | |
| Gene Name | SAN1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 610 | |
| Subcellular Localization | ||
| Protein Description | Plays a specific role in mating-type regulation of yeast, by acting post-translationally to control the stability or activity of the SIR4 proteins.. | |
| Protein Sequence | MSESGQEQNRGTNTSPNNAENNNNSNAASGPLNGGAEQTRNITVSIQYSYFTPERLAHLSNISNNDNNENNSAASGSTIANGTGPSFGIGNGGHQPDGALVLSFRDVPASTPQDRLNSFISVAAQLAMERFNRLLNRPKGISKDEFDKLPVLQVSDLPKAEGPLCSICYDEYEDEVDSTKAKRKRDSENEEESEGTKKRKDNEGAPLRTTADNDSNPSITNATVVEPPSIPLTEQQRTLNDEETNPSYKHSPIKLPCGHIFGRECIYKWSRLENSCPLCRQKISESVGVQRAAQQDTDEVAANEAAFERIRRVLYDPTAVNSTNENSSAPSENTSNTTVPTIGNASSGEQMLSRTGFFLVPQNGQPLHNPVRLPPNDSDRNGVNGPSSTTQNPPSNSGGSNNNQSPRWVPIPLTLFQFHSPNPNPSASDSSASPSAANGPNSNNTSSDATDPHHNRLRAVLDHIFNVAQRGTSDTSATTAPGAQTVHNQGRNDSSSSDTTQGSSFLENISRLTGHFTNGSRDNNNDNNHSNDQQRGGSTGENNRNNLFSSGVASYRNQNGDVTTVELRNNNSAAFPPTDENPSQGQGSSSSDTTIHNDVPNDNNEQRSSQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 14 | Phosphorylation | EQNRGTNTSPNNAEN CCCCCCCCCCCCCCC | 45.45 | 25882841 | |
| 15 | Phosphorylation | QNRGTNTSPNNAENN CCCCCCCCCCCCCCC | 27.92 | 23749301 | |
| 25 | Phosphorylation | NAENNNNSNAASGPL CCCCCCCCCCCCCCC | 29.93 | 23749301 | |
| 110 | Phosphorylation | SFRDVPASTPQDRLN EEECCCCCCCHHHHH | 34.25 | 30377154 | |
| 118 | Phosphorylation | TPQDRLNSFISVAAQ CCHHHHHHHHHHHHH | 28.66 | 30377154 | |
| 139 | Ubiquitination | NRLLNRPKGISKDEF HHHHCCCCCCCHHHH | 66.69 | 17644757 | |
| 143 | Acetylation | NRPKGISKDEFDKLP CCCCCCCHHHHCCCC | 60.40 | 24489116 | |
| 143 | Ubiquitination | NRPKGISKDEFDKLP CCCCCCCHHHHCCCC | 60.40 | 24961812 | |
| 148 | Ubiquitination | ISKDEFDKLPVLQVS CCHHHHCCCCEEEHH | 61.07 | 17644757 | |
| 159 | Ubiquitination | LQVSDLPKAEGPLCS EEHHCCCCCCCCCEE | 67.38 | 17644757 | |
| 180 | Ubiquitination | EDEVDSTKAKRKRDS CCHHCCHHHHHHCCC | 56.73 | 17644757 | |
| 187 | Phosphorylation | KAKRKRDSENEEESE HHHHHCCCCCHHHCC | 46.48 | 27717283 | |
| 197 | Ubiquitination | EEESEGTKKRKDNEG HHHCCCCCCCCCCCC | 62.53 | 22106047 | |
| 198 | Ubiquitination | EESEGTKKRKDNEGA HHCCCCCCCCCCCCC | 65.60 | 15699485 | |
| 200 | Ubiquitination | SEGTKKRKDNEGAPL CCCCCCCCCCCCCCC | 74.01 | 17644757 | |
| 209 | Phosphorylation | NEGAPLRTTADNDSN CCCCCCCCCCCCCCC | 33.74 | 19779198 | |
| 249 | Ubiquitination | EETNPSYKHSPIKLP CCCCCCCCCCCCCCC | 41.78 | 17644757 | |
| 268 | Ubiquitination | FGRECIYKWSRLENS ECHHHHHHHHHHCCC | 20.84 | 17644757 | |
| 282 | Ubiquitination | SCPLCRQKISESVGV CCHHHHHHHHHHHHH | 28.93 | 23749301 | |
| 395 | Phosphorylation | STTQNPPSNSGGSNN CCCCCCCCCCCCCCC | 44.90 | 27017623 | |
| 397 | Phosphorylation | TQNPPSNSGGSNNNQ CCCCCCCCCCCCCCC | 49.20 | 30377154 | |
| 405 | Phosphorylation | GGSNNNQSPRWVPIP CCCCCCCCCCEEECC | 20.68 | 23749301 | |
| 472 | Phosphorylation | FNVAQRGTSDTSATT HHHHHHCCCCCCCCC | 26.14 | 30377154 | |
| 473 | Phosphorylation | NVAQRGTSDTSATTA HHHHHCCCCCCCCCC | 41.54 | 23749301 | |
| 485 | Phosphorylation | TTAPGAQTVHNQGRN CCCCCCCCCCCCCCC | 24.17 | 23749301 | |
| 494 | Phosphorylation | HNQGRNDSSSSDTTQ CCCCCCCCCCCCCCC | 35.35 | 27214570 | |
| 495 | Phosphorylation | NQGRNDSSSSDTTQG CCCCCCCCCCCCCCC | 36.40 | 21440633 | |
| 496 | Phosphorylation | QGRNDSSSSDTTQGS CCCCCCCCCCCCCCH | 35.86 | 30377154 | |
| 497 | Phosphorylation | GRNDSSSSDTTQGSS CCCCCCCCCCCCCHH | 40.71 | 23749301 | |
| 499 | Phosphorylation | NDSSSSDTTQGSSFL CCCCCCCCCCCHHHH | 23.98 | 19779198 | |
| 503 | Phosphorylation | SSDTTQGSSFLENIS CCCCCCCHHHHHHHH | 14.22 | 27017623 | |
| 504 | Phosphorylation | SDTTQGSSFLENISR CCCCCCHHHHHHHHH | 40.45 | 27017623 | |
| 538 | Phosphorylation | NDQQRGGSTGENNRN CCCCCCCCCCCCCCC | 35.74 | 23749301 | |
| 608 | Phosphorylation | NDNNEQRSSQ----- CCCCCCCCCC----- | 32.55 | 21440633 | |
| 609 | Phosphorylation | DNNEQRSSQ------ CCCCCCCCC------ | 41.94 | 21440633 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SAN1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SAN1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SAN1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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