LCL3_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LCL3_YEAST
• UniProt AC: P53153
• Protein Name: Probable endonuclease LCL3
• Gene Name: LCL3
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 274
• Subcellular Localization: Mitochondrion . Membrane ; Single-pass membrane protein .
• Protein Sequence: MREGDSNSKKSADVAVLSIILTGSTLTLIYTYKRYLTQFKRTNDIPRRIFRKHWLYGKVTSVGDGDNFHFFHMPGGIRGGWGWLRPVPQMIKNDSTAEKLVGDSRNMRFFNFNWITHGRSTKSKIQKAKSQFLKLNVPYKNRKNLPTIPIRLCGIDAPERAHFGNPAQPFGNEALIWLQNRILGKKVWVKPLSIDQYNRCVARVSYWDWFGGWKDLSLEMLKDGLAVVYEGKVNTEFDDREDKYRYYEFLARSRKKGLWIQNKFETPGEYKKRI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
104	Phosphorylation	AEKLVGDSRNMRFFN HHHHHCCCCCCEEEE	21.45	28889911
266	Phosphorylation	WIQNKFETPGEYKKR EEECCCCCCCCCCCC	39.46	21126336

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LCL3_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LCL3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LCL3_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SSB1_YEAST	SSB1	physical	22940862
HBT1_YEAST	HBT1	genetic	27708008
YPS5_YEAST	YPS5	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.