| UniProt ID | LHS1_YEAST | |
|---|---|---|
| UniProt AC | P36016 | |
| Protein Name | Heat shock protein 70 homolog LHS1 | |
| Gene Name | LHS1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 881 | |
| Subcellular Localization | Endoplasmic reticulum lumen. | |
| Protein Description | Chaperone required for protein translocation and folding in the endoplasmic reticulum.. | |
| Protein Sequence | MRNVLRLLFLTAFVAIGSLAAVLGVDYGQQNIKAIVVSPQAPLELVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLATRFPQNTLLHLKPLLGKSLEDETTVTLYSKQHPGLEMVSTNRSTIAFLVDNVEYPLEELVAMNVQEIANRANSLLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSVAVNFVLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQPVTIEFEGYGYNPHLGGAKFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAKLILSANSEASINIESLINDIDFRTSITRQEFEEFIADSLLDIVKPINDAVTKQFGGYGTNLPEINGVILAGGSSRIPIVQDQLIKLVSEEKVLRNVNADESAVNGVVMRGIKLSNSFKTKPLNVVDRSVNTYSFKLSNESELYDVFTRGSAYPNKTSILTNTTDSIPNNFTIDLFENGKLFETITVNSGAIKNSYSSDKCSSGVAYNITFDLSSDRLFSIQEVNCICQSENDIGNSKQIKNKGSRLAFTSEDVEIKRLSPSERSRLHEHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMDDEVMQNGPKSQVEELSEMVKVYLDWLEDASFDTDPEDIVSRIREIGILKKKIELYMDSAKEPLNSQQFKGMLEEGHKLLQAIETHKNTVEEFLSQFETEFADTIDNVREEFKKIKQPAYVSKALSTWEETLTSFKNSISEIEKFLAKNLFGEDLREHLFEIKLQFDMYRTKLEEKLRLIKSGDESRLNEIKKLHLRNFRLQKRKEEKLKRKLEQEKSRNNNETESTVINSADDKTTIVNDKTTESNPSSEEDILHDEL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 60 | Phosphorylation | RKEISGLSIKRLPGY HCCCCCCEEEECCCC | 29.59 | 28889911 | |
| 69 | Acetylation | KRLPGYGKDDPNGIE EECCCCCCCCCCCHH | 50.93 | 24489116 | |
| 81 | Phosphorylation | GIERIYGSAVGSLAT CHHHHHHHHHHHHHH | 11.65 | 27017623 | |
| 128 | N-linked_Glycosylation | GLEMVSTNRSTIAFL CEEEEEECCCEEEEE | 28.53 | - | |
| 233 | Phosphorylation | PPGEQQHYIVYDMGS CCCCCCEEEEEECCC | 6.42 | 28889911 | |
| 240 | Phosphorylation | YIVYDMGSGSIKASM EEEEECCCCCEEEEH | 23.80 | 28889911 | |
| 405 | Acetylation | IVQDQLIKLVSEEKV HHHHHHHHHHCHHHH | 51.97 | 24489116 | |
| 458 | N-linked_Glycosylation | TYSFKLSNESELYDV EEEEECCCHHHHHEE | 68.22 | - | |
| 474 | N-linked_Glycosylation | TRGSAYPNKTSILTN HCCCCCCCCCEEEEC | 47.78 | - | |
| 481 | N-linked_Glycosylation | NKTSILTNTTDSIPN CCCEEEECCCCCCCC | 37.22 | - | |
| 489 | N-linked_Glycosylation | TTDSIPNNFTIDLFE CCCCCCCCEEEEEEE | 30.04 | - | |
| 527 | N-linked_Glycosylation | CSSGVAYNITFDLSS CCCCEEEEEEEECCC | 19.65 | - | |
| 579 | Phosphorylation | DVEIKRLSPSERSRL CCEEEECCHHHHHHH | 30.34 | 22369663 | |
| 581 | Phosphorylation | EIKRLSPSERSRLHE EEEECCHHHHHHHHH | 42.12 | 22369663 | |
| 633 | Phosphorylation | VMQNGPKSQVEELSE HHHHCCHHHHHHHHH | 42.46 | 27017623 | |
| 639 | Phosphorylation | KSQVEELSEMVKVYL HHHHHHHHHHHHHHH | 27.25 | 27017623 | |
| 645 | Phosphorylation | LSEMVKVYLDWLEDA HHHHHHHHHHHHHHC | 8.01 | 27017623 | |
| 748 | Phosphorylation | AYVSKALSTWEETLT HHHHHHHHHHHHHHH | 36.01 | 27017623 | |
| 749 | Phosphorylation | YVSKALSTWEETLTS HHHHHHHHHHHHHHH | 37.43 | 27017623 | |
| 753 | Phosphorylation | ALSTWEETLTSFKNS HHHHHHHHHHHHHHH | 24.66 | 27017623 | |
| 760 | Phosphorylation | TLTSFKNSISEIEKF HHHHHHHHHHHHHHH | 28.25 | 27017623 | |
| 762 | Phosphorylation | TSFKNSISEIEKFLA HHHHHHHHHHHHHHH | 32.13 | 27017623 | |
| 766 | Acetylation | NSISEIEKFLAKNLF HHHHHHHHHHHHHCC | 51.87 | 24489116 | |
| 844 | N-linked_Glycosylation | QEKSRNNNETESTVI HHHHHCCCCCCCEEE | 62.20 | - | |
| 846 | Phosphorylation | KSRNNNETESTVINS HHHCCCCCCCEEEEC | 37.04 | 28889911 | |
| 871 | Phosphorylation | KTTESNPSSEEDILH CCCCCCCCCHHHHCC | 55.41 | 21551504 | |
| 872 | Phosphorylation | TTESNPSSEEDILHD CCCCCCCCHHHHCCC | 46.38 | 21551504 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LHS1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LHS1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LHS1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
