XBP1_YEAST - dbPTM
XBP1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID XBP1_YEAST
UniProt AC P40489
Protein Name Transcriptional repressor XBP1
Gene Name XBP1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 647
Subcellular Localization Nucleus .
Protein Description Transcriptional repressor which binds to the consensus sequence 5'-GCCTCGA[G/A]G[C/A]-3'. Represses CLN1 transcription..
Protein Sequence MKYPAFSINSDTVHLTDNPLDDYQRLYLVSVLDRDSPPASFSAGLNIRKVNYKSSIAAQFTHPNFIISARDAGNGEEAAAQNVLNCFEYQFPNLQTIQSLVHEQTLLSQLASSATPHSALHLHDKNILMGKIILPSRSNKTPVSASPTKQEKKALSTASRENATSSLTKNQQFKLTKMDHNLINDKLINPNNCVIWSHDSGYVFMTGIWRLYQDVMKGLINLPRGDSVSTSQQQFFCKAEFEKILSFCFYNHSSFTSEESSSVLLSSSTSSPPKRRTSTGSTFLDANASSSSTSSTQANNYIDFHWNNIKPELRDLICQSYKDFLINELGPDQIDLPNLNPANFTKRIRGGYIKIQGTWLPMEISRLLCLRFCFPIRYFLVPIFGPDFPKDCESWYLAHQNVTFASSTTGAGAATAATAAANTSTNFTSTAVARPRQKPRPRPRQRSTSMSHSKAQKLVIEDALPSFDSFVENLGLSSNDKNFIKKNSKRQKSSTYTSQTSSPIGPRDPTVQILSNLASFYNTHGHRYSYPGNIYIPQQRYSLPPPNQLSSPQRQLNYTYDHIHPVPSQYQSPRHYNVPSSPIAPAPPTFPQPYGDDHYHFLKYASEVYKQQNQRPAHNTNTNMDTSFSPRANNSLNNFKFKTNSKQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
53UbiquitinationNIRKVNYKSSIAAQF
CEEECCCCCCEEEEC		32.3017644757
131AcetylationDKNILMGKIILPSRS
CCCEEEEEEECCCCC		16.7717397211
141PhosphorylationLPSRSNKTPVSASPT
CCCCCCCCCCCCCCC		32.9219684113
144PhosphorylationRSNKTPVSASPTKQE
CCCCCCCCCCCCHHH		25.0029734811
146PhosphorylationNKTPVSASPTKQEKK
CCCCCCCCCCHHHHH		26.1223749301
271PhosphorylationLLSSSTSSPPKRRTS
EEECCCCCCCCCCCC		45.3628889911
448PhosphorylationPRPRQRSTSMSHSKA
CCCCCCCCCCCHHHH		30.5528889911
451PhosphorylationRQRSTSMSHSKAQKL
CCCCCCCCHHHHHHH		25.1128889911
502PhosphorylationTYTSQTSSPIGPRDP
CCCCCCCCCCCCCCC		24.7528889911
530PhosphorylationTHGHRYSYPGNIYIP
HCCCCCCCCCCEEEC		13.2619779198
551PhosphorylationPPPNQLSSPQRQLNY
CCCCCCCCCCHHHCC		33.3728889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of XBP1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of XBP1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of XBP1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CG22_YEASTCLB2genetic
11340165
SNT2_YEASTSNT2physical
16554755
YP216_YEASTYPL216Wphysical
16554755
NRG2_YEASTNRG2genetic
20959818
SWI6_YEASTSWI6genetic
20959818
UME1_YEASTUME1physical
21467995
RPD3_YEASTRPD3physical
21467995
SIN3_YEASTSIN3physical
21467995
SIN3_YEASTSIN3genetic
21467995
SWI4_YEASTSWI4genetic
21127252
CG13_YEASTCLN3genetic
24204289
RL22A_YEASTRPL22Agenetic
27708008
AIM4_YEASTAIM4genetic
27708008
STP1_YEASTSTP1genetic
27708008
YGY0_YEASTYGL230Cgenetic
27708008
RS25A_YEASTRPS25Agenetic
27708008
UBCX_YEASTPEX4genetic
27708008
PHB2_YEASTPHB2genetic
27708008
AIM18_YEASTAIM18genetic
27708008
DAL81_YEASTDAL81genetic
27708008
ENV10_YEASTENV10genetic
27708008
YL225_YEASTYLR225Cgenetic
27708008
GBLP_YEASTASC1genetic
27708008
SIW14_YEASTSIW14genetic
27708008
OCA2_YEASTOCA2genetic
27708008
TPM1_YEASTTPM1genetic
27708008
HIR2_YEASTHIR2genetic
27708008
HAP5_YEASTHAP5genetic
27708008
YME1_YEASTYME1genetic
27708008
SRO7_YEASTSRO7genetic
27708008
MED1_YEASTMED1genetic
27708008
VPS4_YEASTVPS4genetic
27708008
QCR2_YEASTQCR2genetic
27708008
DPH5_YEASTDPH5genetic
29674565
NIP80_YEASTNIP100genetic
29674565
RTC6_YEASTRTC6genetic
29674565
ATPN_YEASTATP20genetic
29674565
CAP_YEASTSRV2genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of XBP1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-146, AND MASSSPECTROMETRY.

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