| UniProt ID | HPF1_YEAST | |
|---|---|---|
| UniProt AC | Q05164 | |
| Protein Name | Haze protective factor 1 | |
| Gene Name | HPF1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 967 | |
| Subcellular Localization |
Secreted, cell wall. Membrane Lipid-anchor, GPI-anchor. Covalently-linked GPI-modified cell wall protein (GPI-CWP), enriched at bud sites and their neighborhood. |
|
| Protein Description | Involved in cell wall organization and biosynthesis.. | |
| Protein Sequence | MFNRFNKLQAALALVLYSQSALGQYYTNSSSIASNSSTAVSSTSSGSVSISSSIELTSSTSDVSSSLTELTSSSTEVSSSIAPSTSSSEVSSSITSSGSSVSGSSSITSSGSSVSSSSSATESGSSASGSSSATESGSSVSGSSTSITSGSSSATESGSSVSGSTSATESGSSASGSSSATESGSSASGSSSATESGSSVSGSSSATESGSSVSGSSSATESGSASSVPSSSGSVTESGSSSSASESSITQSGTASGSSASSTSGSVTQSGSSVSGSSASSAPGISSSIPQSTSSASTASGSITSGTLSSITSSASSATATASNSLSSSDGTIYLPSTTISGDITLTGSVIATEAVEVAAGGKLTLLDGDKYVFSADFIIHGGVFVEKSKPTYPGTEFDISGENFDVSGTFNAEEPAASSASAYSFTPGSFDNSGDISLSLSESTKGEVTFSPYSNSGAFSFSNAILNGGSVSGLQRRAESGSVNNGEINLENGSTYVVVEPVSGSGTINIISGNLYLHYPDTFTGQTVVFKGEGVLAVDPTETNTTPIPVVGYTGENQIAITADVTALSYDSATGVLTATQGNSQFSFSIGTGFSSSGFNVSEGTFAGAYAYYLNYGGVVASSATPSSTSTTSGATNSTSGSTSFGASVTGSTASTSFGASVTGSTASTLISGSPSVYTTTLTYATTTSTVVVSCSETTDSNGNVYTITTTVPCSSTTATITSCDETGCHVTTSTGTVATETVSSKSYTTVTVTHCDNNGCNTKTVTSECPEETSATTTSPKSYTTVTVTHCDDNGCNTKTVTSEAPEATTTTVSPKTYTTATVTQCDDNGCSTKTVTSEAPKETSETSETSAAPKTYTTATVTQCDDNGCNVKIITSQIPEATSTVTATSASPKSYTTVTSEGSKATSLTTAISKASSAISTYSKSAAPIKTSTGIIVQSEGIAAGLNANTLNALVGIFVLAFFN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 28 | N-linked_Glycosylation | ALGQYYTNSSSIASN HCCCCCCCCCCCCCC | 24.63 | - | |
| 35 | N-linked_Glycosylation | NSSSIASNSSTAVSS CCCCCCCCCCCCEEE | 30.84 | - | |
| 493 | N-linked_Glycosylation | NGEINLENGSTYVVV CCEEECCCCCEEEEE | 53.53 | - | |
| 601 | N-linked_Glycosylation | GFSSSGFNVSEGTFA CCCCCCEEECCCEEH | 39.67 | - | |
| 638 | N-linked_Glycosylation | STTSGATNSTSGSTS CCCCCCCCCCCCCCE | 42.63 | - | |
| 781 | Phosphorylation | ETSATTTSPKSYTTV CCCCCCCCCCCEEEE | 28.39 | 23749301 | |
| 783 | Ubiquitination | SATTTSPKSYTTVTV CCCCCCCCCEEEEEE | 56.73 | 23749301 | |
| 816 | Phosphorylation | EATTTTVSPKTYTTA CCEECEECCCEEEEE | 20.70 | 23749301 | |
| 844 | Ubiquitination | TVTSEAPKETSETSE EECCCCCCCCCCCCC | 79.33 | 23749301 | |
| 892 | Phosphorylation | TSTVTATSASPKSYT CCEEEEECCCCCCEE | 25.04 | 23749301 | |
| 894 | Phosphorylation | TVTATSASPKSYTTV EEEEECCCCCCEEEE | 32.40 | 23749301 | |
| 927 | Ubiquitination | SAISTYSKSAAPIKT HHHHHCCCCCCCCEE | 33.43 | 23749301 | |
| 946 | GPI-anchor | IVQSEGIAAGLNANT EEECCCHHCCCCHHH | 13.31 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HPF1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HPF1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HPF1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| BIT2_YEAST | BIT2 | genetic | 20093466 | |
| RT31_YEAST | YMR31 | genetic | 20093466 | |
| MAD1_YEAST | MAD1 | genetic | 20093466 | |
| RL24A_YEAST | RPL24A | genetic | 20093466 | |
| PCP1_YEAST | PCP1 | genetic | 20093466 | |
| NMD2_YEAST | NMD2 | genetic | 20093466 | |
| SAC1_YEAST | SAC1 | genetic | 20093466 | |
| DCOR_YEAST | SPE1 | genetic | 20093466 | |
| ADE_YEAST | AAH1 | genetic | 20093466 | |
| HRB1_YEAST | HRB1 | genetic | 20093466 | |
| COQ10_YEAST | COQ10 | genetic | 20093466 | |
| SIN3_YEAST | SIN3 | genetic | 20093466 | |
| CY1_YEAST | CYT1 | genetic | 20093466 | |
| COQ7_YEAST | CAT5 | genetic | 20093466 | |
| DDC1_YEAST | DDC1 | genetic | 20093466 | |
| MTU1_YEAST | SLM3 | genetic | 27708008 | |
| RL24B_YEAST | RPL24B | genetic | 27708008 | |
| FLX1_YEAST | FLX1 | genetic | 27708008 | |
| VPS53_YEAST | VPS53 | genetic | 27708008 | |
| AEP2_YEAST | AEP2 | genetic | 27708008 | |
| CY1_YEAST | CYT1 | genetic | 27708008 | |
| DIA2_YEAST | DIA2 | genetic | 27708008 | |
| COQ7_YEAST | CAT5 | genetic | 27708008 | |
| MAGAB_HUMAN | MAGEA11 | physical | 27107014 | |
| SPOP_HUMAN | SPOP | physical | 27107014 | |
| SNT1_YEAST | SNT1 | genetic | 29674565 | |
| LCB2_YEAST | LCB2 | genetic | 29674565 | |
| LCB1_YEAST | LCB1 | genetic | 29674565 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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