UniProt ID | HPF1_YEAST | |
---|---|---|
UniProt AC | Q05164 | |
Protein Name | Haze protective factor 1 | |
Gene Name | HPF1 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 967 | |
Subcellular Localization |
Secreted, cell wall. Membrane Lipid-anchor, GPI-anchor. Covalently-linked GPI-modified cell wall protein (GPI-CWP), enriched at bud sites and their neighborhood. |
|
Protein Description | Involved in cell wall organization and biosynthesis.. | |
Protein Sequence | MFNRFNKLQAALALVLYSQSALGQYYTNSSSIASNSSTAVSSTSSGSVSISSSIELTSSTSDVSSSLTELTSSSTEVSSSIAPSTSSSEVSSSITSSGSSVSGSSSITSSGSSVSSSSSATESGSSASGSSSATESGSSVSGSSTSITSGSSSATESGSSVSGSTSATESGSSASGSSSATESGSSASGSSSATESGSSVSGSSSATESGSSVSGSSSATESGSASSVPSSSGSVTESGSSSSASESSITQSGTASGSSASSTSGSVTQSGSSVSGSSASSAPGISSSIPQSTSSASTASGSITSGTLSSITSSASSATATASNSLSSSDGTIYLPSTTISGDITLTGSVIATEAVEVAAGGKLTLLDGDKYVFSADFIIHGGVFVEKSKPTYPGTEFDISGENFDVSGTFNAEEPAASSASAYSFTPGSFDNSGDISLSLSESTKGEVTFSPYSNSGAFSFSNAILNGGSVSGLQRRAESGSVNNGEINLENGSTYVVVEPVSGSGTINIISGNLYLHYPDTFTGQTVVFKGEGVLAVDPTETNTTPIPVVGYTGENQIAITADVTALSYDSATGVLTATQGNSQFSFSIGTGFSSSGFNVSEGTFAGAYAYYLNYGGVVASSATPSSTSTTSGATNSTSGSTSFGASVTGSTASTSFGASVTGSTASTLISGSPSVYTTTLTYATTTSTVVVSCSETTDSNGNVYTITTTVPCSSTTATITSCDETGCHVTTSTGTVATETVSSKSYTTVTVTHCDNNGCNTKTVTSECPEETSATTTSPKSYTTVTVTHCDDNGCNTKTVTSEAPEATTTTVSPKTYTTATVTQCDDNGCSTKTVTSEAPKETSETSETSAAPKTYTTATVTQCDDNGCNVKIITSQIPEATSTVTATSASPKSYTTVTSEGSKATSLTTAISKASSAISTYSKSAAPIKTSTGIIVQSEGIAAGLNANTLNALVGIFVLAFFN | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
28 | N-linked_Glycosylation | ALGQYYTNSSSIASN HCCCCCCCCCCCCCC | 24.63 | - | |
35 | N-linked_Glycosylation | NSSSIASNSSTAVSS CCCCCCCCCCCCEEE | 30.84 | - | |
493 | N-linked_Glycosylation | NGEINLENGSTYVVV CCEEECCCCCEEEEE | 53.53 | - | |
601 | N-linked_Glycosylation | GFSSSGFNVSEGTFA CCCCCCEEECCCEEH | 39.67 | - | |
638 | N-linked_Glycosylation | STTSGATNSTSGSTS CCCCCCCCCCCCCCE | 42.63 | - | |
781 | Phosphorylation | ETSATTTSPKSYTTV CCCCCCCCCCCEEEE | 28.39 | 23749301 | |
783 | Ubiquitination | SATTTSPKSYTTVTV CCCCCCCCCEEEEEE | 56.73 | 23749301 | |
816 | Phosphorylation | EATTTTVSPKTYTTA CCEECEECCCEEEEE | 20.70 | 23749301 | |
844 | Ubiquitination | TVTSEAPKETSETSE EECCCCCCCCCCCCC | 79.33 | 23749301 | |
892 | Phosphorylation | TSTVTATSASPKSYT CCEEEEECCCCCCEE | 25.04 | 23749301 | |
894 | Phosphorylation | TVTATSASPKSYTTV EEEEECCCCCCEEEE | 32.40 | 23749301 | |
927 | Ubiquitination | SAISTYSKSAAPIKT HHHHHCCCCCCCCEE | 33.43 | 23749301 | |
946 | GPI-anchor | IVQSEGIAAGLNANT EEECCCHHCCCCHHH | 13.31 | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HPF1_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HPF1_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HPF1_YEAST !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
BIT2_YEAST | BIT2 | genetic | 20093466 | |
RT31_YEAST | YMR31 | genetic | 20093466 | |
MAD1_YEAST | MAD1 | genetic | 20093466 | |
RL24A_YEAST | RPL24A | genetic | 20093466 | |
PCP1_YEAST | PCP1 | genetic | 20093466 | |
NMD2_YEAST | NMD2 | genetic | 20093466 | |
SAC1_YEAST | SAC1 | genetic | 20093466 | |
DCOR_YEAST | SPE1 | genetic | 20093466 | |
ADE_YEAST | AAH1 | genetic | 20093466 | |
HRB1_YEAST | HRB1 | genetic | 20093466 | |
COQ10_YEAST | COQ10 | genetic | 20093466 | |
SIN3_YEAST | SIN3 | genetic | 20093466 | |
CY1_YEAST | CYT1 | genetic | 20093466 | |
COQ7_YEAST | CAT5 | genetic | 20093466 | |
DDC1_YEAST | DDC1 | genetic | 20093466 | |
MTU1_YEAST | SLM3 | genetic | 27708008 | |
RL24B_YEAST | RPL24B | genetic | 27708008 | |
FLX1_YEAST | FLX1 | genetic | 27708008 | |
VPS53_YEAST | VPS53 | genetic | 27708008 | |
AEP2_YEAST | AEP2 | genetic | 27708008 | |
CY1_YEAST | CYT1 | genetic | 27708008 | |
DIA2_YEAST | DIA2 | genetic | 27708008 | |
COQ7_YEAST | CAT5 | genetic | 27708008 | |
MAGAB_HUMAN | MAGEA11 | physical | 27107014 | |
SPOP_HUMAN | SPOP | physical | 27107014 | |
SNT1_YEAST | SNT1 | genetic | 29674565 | |
LCB2_YEAST | LCB2 | genetic | 29674565 | |
LCB1_YEAST | LCB1 | genetic | 29674565 |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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