BIT2_YEAST - dbPTM
BIT2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BIT2_YEAST
UniProt AC P38346
Protein Name Probable target of rapamycin complex 2 subunit BIT2
Gene Name BIT2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 545
Subcellular Localization
Protein Description
Protein Sequence MATDLNRKRSATSGSLSVTNPNIKATNRKPARVYSVSSDIVPQALTHPDEDVHLKTSKSPHDAAPRWSQVGFQSIFHDGSNARRSTDSIEEEYSQGTENNDGHSEIGSSSSNRMEGNTTSNDSLFSSNSRGNKRRLSIFTNSKDNMRNRSRSGSKNYGTVITGTSSNNISRSGSKLFHTKSNMSVNSLQSSLSTGHSHSNKGSNVFSKMAKKLLPYKPHNSIGKDDVEPVVPSPFSKFLHSSYGKHRSPVQFIHTSTGGLIDSGKSVYSFNPSINNNPNDTALSLIQDDAFDATNVSLLHDLLKNLPSLIANYKSFTVQELFVLEGNIWGIYCSIVVELFKNKRVWQLPAKIEDIDRLLEFYITLKTQTKAAVTHSRFLAEIEEFITTSLYILENQIVFNYANEDTVNTALKRVGIIWKVFYQQVYYDMMAVLLPFEKSFQKNSNYWLDGYLSEPSRYAPSIDVLLLKCFRDSIILPYYESFLHTNDGASKSFQRYIFSEEEQNGVTEEDKLTLLQCFGILNTIKGNSRNQRIIGELLEGIRMSI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationTDLNRKRSATSGSLS
CCCCCCCCCCCCCCC
38.6425752575
12PhosphorylationLNRKRSATSGSLSVT
CCCCCCCCCCCCCCC
34.5628889911
15PhosphorylationKRSATSGSLSVTNPN
CCCCCCCCCCCCCCC
19.7628889911
26PhosphorylationTNPNIKATNRKPARV
CCCCCCCCCCCCCEE
30.4724961812
34PhosphorylationNRKPARVYSVSSDIV
CCCCCEEEEECCCCC
9.5919779198
35PhosphorylationRKPARVYSVSSDIVP
CCCCEEEEECCCCCC
16.8019779198
37PhosphorylationPARVYSVSSDIVPQA
CCEEEEECCCCCCHH
19.1619779198
38PhosphorylationARVYSVSSDIVPQAL
CEEEEECCCCCCHHH
29.2419779198
46PhosphorylationDIVPQALTHPDEDVH
CCCCHHHCCCCCCCC
34.0924961812
59PhosphorylationVHLKTSKSPHDAAPR
CCCCCCCCCCCCCCC
27.5128889911
120PhosphorylationRMEGNTTSNDSLFSS
CCCCCCCCCCCCCCC
36.2828889911
137PhosphorylationRGNKRRLSIFTNSKD
CCCCCEEEEECCCHH
17.5328889911
154PhosphorylationRNRSRSGSKNYGTVI
CCCCCCCCCCCCEEE
20.9730377154
157PhosphorylationSRSGSKNYGTVITGT
CCCCCCCCCEEEECC
20.2230377154
162PhosphorylationKNYGTVITGTSSNNI
CCCCEEEECCCCCCC
30.0330377154
164PhosphorylationYGTVITGTSSNNISR
CCEEEECCCCCCCCC
21.9730377154
170PhosphorylationGTSSNNISRSGSKLF
CCCCCCCCCCCCEEE
23.6328889911
184PhosphorylationFHTKSNMSVNSLQSS
EECCCCCCHHHHHHH
23.5427017623
190PhosphorylationMSVNSLQSSLSTGHS
CCHHHHHHHHHCCCC
38.2427017623
197PhosphorylationSSLSTGHSHSNKGSN
HHHHCCCCCCCCCCC
29.9227017623
199PhosphorylationLSTGHSHSNKGSNVF
HHCCCCCCCCCCCHH
43.1627017623
207PhosphorylationNKGSNVFSKMAKKLL
CCCCCHHHHHHHHHC
19.7627017623
233PhosphorylationDVEPVVPSPFSKFLH
CCCCCCCCCHHHHHH
27.2824930733
256PhosphorylationPVQFIHTSTGGLIDS
CCEEEEECCCCCCCC
15.7627214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BIT2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BIT2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BIT2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EI2BA_YEASTGCN3physical
10688190
TAF9_YEASTTAF9physical
10688190
SLM1_YEASTSLM1physical
10688190
YAP6_YEASTYAP6physical
11283351
SLM1_YEASTSLM1physical
11283351
EI2BA_YEASTGCN3physical
11283351
ATG17_YEASTATG17physical
11283351
SLM2_YEASTSLM2physical
11283351
SPC29_YEASTSPC29physical
11283351
BBP1_YEASTBBP1physical
11283351
SGF29_YEASTSGF29genetic
20093466
RIM1_YEASTRIM1genetic
20093466
SLX5_YEASTSLX5genetic
20093466
HMO1_YEASTHMO1genetic
20093466
RS17B_YEASTRPS17Bgenetic
20093466
BOI2_YEASTBOI2genetic
20093466
BST1_YEASTBST1genetic
20093466
MPC1_YEASTMPC1genetic
20093466
TFS2_YEASTDST1genetic
20093466
RPN14_YEASTRPN14genetic
20093466
RS27B_YEASTRPS27Bgenetic
20093466
HXT5_YEASTHXT5genetic
20093466
FKH1_YEASTFKH1genetic
20093466
FIS1_YEASTFIS1genetic
20093466
MRX5_YEASTYJL147Cgenetic
20093466
IF4A_YEASTTIF2genetic
20093466
YJ24_YEASTKCH1genetic
20093466
SAC1_YEASTSAC1genetic
20093466
IXR1_YEASTIXR1genetic
20093466
DNM1_YEASTDNM1genetic
20093466
PAU4_YEASTPAU4genetic
20093466
PFKA2_YEASTPFK2genetic
20093466
KC12_YEASTYCK2genetic
20093466
EFM6_YEASTYNL024Cgenetic
20093466
RCM1_YEASTRCM1genetic
20093466
YN8B_YEASTYNR021Wgenetic
20093466
YO159_YEASTYOL159Cgenetic
20093466
HPF1_YEASTHPF1genetic
20093466
REXO4_YEASTREX4genetic
20093466
OST3_YEASTOST3genetic
20093466
RAS1_YEASTRAS1genetic
20093466
VPH1_YEASTVPH1genetic
20093466
RLM1_YEASTRLM1genetic
20093466
RAD1_YEASTRAD1genetic
20093466
MSS18_YEASTMSS18genetic
20093466
ATC3_YEASTDRS2genetic
27708008
HAP3_YEASTHAP3genetic
27708008
UBP14_YEASTUBP14genetic
27708008
SGF29_YEASTSGF29genetic
27708008
RIM1_YEASTRIM1genetic
27708008
THRC_YEASTTHR4genetic
27708008
IMG2_YEASTIMG2genetic
27708008
RS17B_YEASTRPS17Bgenetic
27708008
BOI2_YEASTBOI2genetic
27708008
BST1_YEASTBST1genetic
27708008
RPN14_YEASTRPN14genetic
27708008
AZR1_YEASTAZR1genetic
27708008
HXT5_YEASTHXT5genetic
27708008
FKH1_YEASTFKH1genetic
27708008
IF4A_YEASTTIF2genetic
27708008
YJ24_YEASTKCH1genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
ENT3_YEASTENT3genetic
27708008
IXR1_YEASTIXR1genetic
27708008
DNM1_YEASTDNM1genetic
27708008
ERFB_YEASTERF2genetic
27708008
RCO1_YEASTRCO1genetic
27708008
PFKA2_YEASTPFK2genetic
27708008
RCM1_YEASTRCM1genetic
27708008
EFM6_YEASTYNL024Cgenetic
27708008
KC12_YEASTYCK2genetic
27708008
BRE5_YEASTBRE5genetic
27708008
REXO4_YEASTREX4genetic
27708008
HPF1_YEASTHPF1genetic
27708008
YO159_YEASTYOL159Cgenetic
27708008
STI1_YEASTSTI1genetic
27708008
OST3_YEASTOST3genetic
27708008
TCB1_YEASTTCB1genetic
27708008
RLM1_YEASTRLM1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BIT2_YEAST

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Related Literatures of Post-Translational Modification

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