MAGAB_HUMAN - dbPTM
MAGAB_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MAGAB_HUMAN
UniProt AC P43364
Protein Name Melanoma-associated antigen 11
Gene Name MAGEA11
Organism Homo sapiens (Human).
Sequence Length 429
Subcellular Localization Nucleus . Cytoplasm .
Protein Description Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression..
Protein Sequence METQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDLPRVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESFSPTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALREEGEGV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Methylation-METQFRRGGLGCSP
-CCCCCCCCCCCCCH		44.83115482489
13PhosphorylationRRGGLGCSPASIKRK
CCCCCCCCHHHHCCC		23.0030266825
16PhosphorylationGLGCSPASIKRKKKR
CCCCCHHHHCCCCCC		31.8430266825
20AcetylationSPASIKRKKKREDSG
CHHHHCCCCCCCCCC		58.617681217
76PhosphorylationQANLEDRSPRRTQRI
HCCCCCCCCCCCCCC		34.7729255136
168PhosphorylationEELPAAESPSPPQSP
HHCCCCCCCCCCCCC		26.4222817900
170PhosphorylationLPAAESPSPPQSPQE
CCCCCCCCCCCCCCC		59.5022817900
174PhosphorylationESPSPPQSPQEESFS
CCCCCCCCCCCCCCC		34.0322817900
181PhosphorylationSPQEESFSPTAMDAI
CCCCCCCCHHHHHHH		30.5322817900
199PhosphorylationLSDEGSGSQEKEGPS
CCCCCCCCCCCCCCC		36.5422817900
206PhosphorylationSQEKEGPSTSPDLID
CCCCCCCCCCCCCCC		52.9923663014
207PhosphorylationQEKEGPSTSPDLIDP
CCCCCCCCCCCCCCH		47.6223663014
208PhosphorylationEKEGPSTSPDLIDPE
CCCCCCCCCCCCCHH		22.2823663014
216PhosphorylationPDLIDPESFSQDILH
CCCCCHHHHCCHHHH		35.2723663014
236UbiquitinationLVHLLLRKYRVKGLI
HHHHHHHHHCCCHHH		37.0618212060
237PhosphorylationVHLLLRKYRVKGLIT
HHHHHHHHCCCHHHH		17.76-
240UbiquitinationLLRKYRVKGLITKAE
HHHHHCCCHHHHHHH		38.7118212060
245UbiquitinationRVKGLITKAEMLGSV
CCCHHHHHHHHHHHH		35.041821206
251PhosphorylationTKAEMLGSVIKNYED
HHHHHHHHHHHCHHH		19.39-
256PhosphorylationLGSVIKNYEDYFPEI
HHHHHHCHHHHHHHH		12.74-
360PhosphorylationGEPKRLLTQNWVQEK
CCCCHHHHCCCHHHC		25.1722817900
382PhosphorylationPGTDPACYEFLWGPR
CCCCHHHHHHHHCCC		16.30-
414PhosphorylationNGRDPTSYPSLYEDA
CCCCCCCCHHHHHHH		10.18-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
174SPhosphorylationKinaseMAPK3P27361
GPS
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MAGAB_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MAGAB_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MGME1_HUMANMGME1physical
16189514
LNX1_HUMANLNX1physical
16189514
DJC10_HUMANDNAJC10physical
16189514
MAD3_HUMANMXD3physical
16189514
PSMF1_HUMANPSMF1physical
16189514
CIA30_HUMANNDUFAF1physical
16189514
COX7R_HUMANCOX7A2Lphysical
16189514
NIF3L_HUMANNIF3L1physical
16189514
NOL4_HUMANNOL4physical
16189514
CLUA1_HUMANCLUAP1physical
16189514
ENOX2_HUMANENOX2physical
16189514
AK1C3_HUMANAKR1C3physical
16189514
PKRI1_HUMANPRKRIP1physical
16189514
K0408_HUMANKIAA0408physical
16189514
VTA1_HUMANVTA1physical
16189514
MCRS1_HUMANMCRS1physical
16189514
UB2D4_HUMANUBE2D4physical
16189514
SNX20_HUMANSNX20physical
16189514
PAHX_HUMANPHYHphysical
16189514
OTUB2_HUMANOTUB2physical
16189514
PNKD_HUMANPNKDphysical
16189514
NDEL1_HUMANNDEL1physical
16189514
NDUB9_HUMANNDUFB9physical
16189514
MYOZ1_HUMANMYOZ1physical
16189514
RHG29_HUMANARHGAP29physical
16189514
MLF1_HUMANMLF1physical
16189514
DIEXF_HUMANDIEXFphysical
16189514
ZBT16_HUMANZBTB16physical
16189514
PRDX3_HUMANPRDX3physical
16189514
TRI51_HUMANTRIM51physical
16189514
TRM1_HUMANTRMT1physical
16189514
PORIM_HUMANTMEM123physical
16189514
BEX2_HUMANBEX2physical
16189514
TCF25_HUMANTCF25physical
16189514
TEX37_HUMANTEX37physical
16189514
PNKP_HUMANPNKPphysical
16189514
FA156_HUMANFAM156Aphysical
16189514
ACMSD_HUMANACMSDphysical
16189514
LAS2_HUMANC18orf54physical
16189514
CEP76_HUMANCEP76physical
16189514
TEANC_HUMANTCEANCphysical
16189514
RADIL_HUMANRADILphysical
16189514
NSUN4_HUMANNSUN4physical
16189514
TRI27_HUMANTRIM27physical
16189514
SH24A_HUMANSH2D4Aphysical
16189514
CCD14_HUMANCCDC14physical
16189514
ZSWM2_HUMANZSWIM2physical
16189514
TCEA2_HUMANTCEA2physical
16189514
SNX7_HUMANSNX7physical
16189514
FL2D_HUMANWTAPphysical
16189514
ZN655_HUMANZNF655physical
16189514
CC185_HUMANCCDC185physical
16189514
MED28_HUMANMED28physical
16189514
MAGAB_HUMANMAGEA11physical
18212060
ANDR_HUMANARphysical
18212060
EP300_HUMANEP300physical
20448036
NCOA2_HUMANNCOA2physical
20448036
EGLN1_HUMANEGLN1physical
19147576
PRGR_HUMANPGRphysical
22891251
ANDR_MOUSEArphysical
21730049
ANDR_HUMANARphysical
21730049
GCR_HUMANNR3C1physical
21730049
PRGR_HUMANPGRphysical
21730049
ANDR_HUMANARphysical
19828458
SKP1_HUMANSKP1physical
19828458
NCOA2_HUMANNCOA2physical
19828458
RBL1_HUMANRBL1physical
23853093
RB_HUMANRB1physical
23853093
E2F1_HUMANE2F1physical
23853093
NDUB9_HUMANNDUFB9physical
25416956
NOS3_HUMANNOS3physical
25416956
PIN4_HUMANPIN4physical
25416956
STAR_HUMANSTARphysical
25416956
TPM3_HUMANTPM3physical
25416956
MTA1_HUMANMTA1physical
25416956
JADE3_HUMANJADE3physical
25416956
GNPI1_HUMANGNPDA1physical
25416956
B2L11_HUMANBCL2L11physical
25416956
ENOX2_HUMANENOX2physical
25416956
UBP20_HUMANUSP20physical
25416956
TCF25_HUMANTCF25physical
25416956
CLUA1_HUMANCLUAP1physical
25416956
THIOM_HUMANTXN2physical
25416956
PNKD_HUMANPNKDphysical
25416956
DIEXF_HUMANDIEXFphysical
25416956
DJC10_HUMANDNAJC10physical
25416956
NTAQ1_HUMANWDYHV1physical
25416956
RBM23_HUMANRBM23physical
25416956
DOC10_HUMANDOCK10physical
25416956
TRM1_HUMANTRMT1physical
25416956
RADIL_HUMANRADILphysical
25416956
CC146_HUMANCCDC146physical
25416956
CCD14_HUMANCCDC14physical
25416956
PHS2_HUMANPCBD2physical
25416956
BEX2_HUMANBEX2physical
25416956
PORIM_HUMANTMEM123physical
25416956
SNX20_HUMANSNX20physical
25416956
ACMSD_HUMANACMSDphysical
25416956
LAS2_HUMANC18orf54physical
25416956
CD20B_HUMANCDC20Bphysical
25416956
ZCH12_HUMANZCCHC12physical
25416956
ACO15_HUMANTHEM5physical
25416956
TRM1_HUMANTRMT1physical
21516116
SUV92_HUMANSUV39H2physical
28042025
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MAGAB_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-76, AND MASSSPECTROMETRY.

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