CD20B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CD20B_HUMAN
• UniProt AC: Q86Y33
• Protein Name: Cell division cycle protein 20 homolog B
• Gene Name: CDC20B
• Organism: Homo sapiens (Human).
• Sequence Length: 519
• Protein Sequence: MEWKLERTAPRRVRTEEEMLWESIMRVLSKDLKQKRSQDSANVLDSVNATYSDFKSNFAKRLSAEVPVASSPITTRWQQSQTRALSSDSFGEEQSTTYLPEASGSVLKTPPEKETLTLGSRKEQLKTPSKGISETSNSALHFCKAPHAMDRDWKESVASKGQKCLKQLFVTQNVVQQANGKMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDSILQPEVKIHITGLRNDYYLNILDWSFQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKAMDWCPWQSGVLAIGGGMKDGRLHILDINAGKSIQTPSTNSQICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLSLSPDQTRVFSAAADGTASVWNCY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	Phosphorylation	ESIMRVLSKDLKQKR HHHHHHHCHHHHHHH	22.67	22673903
63	Phosphorylation	SNFAKRLSAEVPVAS HHHHHHHCCCCCEEC	26.81	27251275
70	Phosphorylation	SAEVPVASSPITTRW CCCCCEECCCCCCCH	36.56	20873877
71	Phosphorylation	AEVPVASSPITTRWQ CCCCEECCCCCCCHH	15.58	20873877
74	Phosphorylation	PVASSPITTRWQQSQ CEECCCCCCCHHHHH	17.43	20873877
75	Phosphorylation	VASSPITTRWQQSQT EECCCCCCCHHHHHC	30.54	20873877
86	Phosphorylation	QSQTRALSSDSFGEE HHHCCCCCCCCCCCC	30.99	30576142
89	Phosphorylation	TRALSSDSFGEEQST CCCCCCCCCCCCCCC	36.78	30576142
103	Phosphorylation	TTYLPEASGSVLKTP CCCCCCCCCCCCCCC	29.91	30576142
105	Phosphorylation	YLPEASGSVLKTPPE CCCCCCCCCCCCCCC	23.06	26074081
109	Phosphorylation	ASGSVLKTPPEKETL CCCCCCCCCCCCCEE	39.66	26074081
115	Phosphorylation	KTPPEKETLTLGSRK CCCCCCCEEECCCCH	35.79	26074081
203	Phosphorylation	KDGVRDESFHLKSSG CCCCCCCCEEECCCC	23.43	27251275
208	Phosphorylation	DESFHLKSSGDINDS CCCEEECCCCCCCCC	46.01	26699800
209	Phosphorylation	ESFHLKSSGDINDSI CCEEECCCCCCCCCC	38.61	26699800
215	Phosphorylation	SSGDINDSILQPEVK CCCCCCCCCCCCEEE	22.25	26699800
226	Phosphorylation	PEVKIHITGLRNDYY CEEEEEEECCCCCCC	18.92	24719451
286	Phosphorylation	VSWIKEGTCLAVGTS CEEEECCEEEEEECC	12.87	29900121
304	Phosphorylation	VQLWDVVTKKRLRNM EEEEHHHCHHHHHHH	30.60	29900121
329	Phosphorylation	SWNHFILSSGSRLGR HCCEEEECCCCCCCC	28.04	24043423
330	Phosphorylation	WNHFILSSGSRLGRV CCEEEECCCCCCCCE	37.02	24043423
332	Phosphorylation	HFILSSGSRLGRVYH EEEECCCCCCCCEEE	26.70	24043423
466	Phosphorylation	EIATGQGTPKNDVTV EEECCCCCCCCCEEE	24.17	27251275
475	Phosphorylation	KNDVTVWTCPTVSRS CCCEEEEECCCCCCC	12.31	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CD20B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CD20B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CD20B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCD57_HUMAN	CCDC57	physical	25416956
UBA5_HUMAN	UBA5	physical	26186194
MA2C1_HUMAN	MAN2C1	physical	26186194
HMOX1_HUMAN	HMOX1	physical	26186194
PLK1_HUMAN	PLK1	physical	26186194
FA83H_HUMAN	FAM83H	physical	26186194
MA2C1_HUMAN	MAN2C1	physical	28514442
PLK1_HUMAN	PLK1	physical	28514442
UBA5_HUMAN	UBA5	physical	28514442
HMOX1_HUMAN	HMOX1	physical	28514442
VCIP1_HUMAN	VCPIP1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.