dbPTM

VCIP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VCIP1_HUMAN
UniProt AC	Q96JH7
Protein Name	Deubiquitinating protein VCIP135
Gene Name	VCPIP1
Organism	Homo sapiens (Human).
Sequence Length	1222
Subcellular Localization	Endoplasmic reticulum. Golgi apparatus, Golgi stack. Associated with Golgi stacks and endoplasmic reticulum..
Protein Description	Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains..
Protein Sequence	MSQPPPPPPPLPPPPPPPEAPQTPSSLASAAASGGLLKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGKDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRTDKNYSFPLNNLVCSYDSVKDVLVPDYGMSNLTACNWCHGTSVRKVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWDGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDSSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQESESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKSKAEGGQSAAAHSAHTVKQEDIAVTGKLSSKELQEQAEKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYSIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASGNPHLDPRARETSVVRKHNTGTDFSNSSTKTEPSVFTASSSNSELIRIAPGVVTMRDGRQLDPDLVEAQRKKLQEMVSSIQASMDRHLRDQSTEQSPSDLPQRKTEVVSSSAKSGSLQTGLPESFPLTGGTENLNTETTDGCVADALGAAFATRSKAQRGNSVEELEEMDSQDAEMTNTTEPMDHS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSQPPPPPP ------CCCCCCCCC	63.80	28348404
23	Phosphorylation	PPPEAPQTPSSLASA CCCCCCCCCCHHHHH	24.87	24719451
25	Phosphorylation	PEAPQTPSSLASAAA CCCCCCCCHHHHHHH	41.18	28348404
26	Phosphorylation	EAPQTPSSLASAAAS CCCCCCCHHHHHHHH	29.20	28348404
46	Phosphorylation	RRDRRILSGSCPDPK HHCCCCCCCCCCCCC	26.70	29978859
48	Phosphorylation	DRRILSGSCPDPKCQ CCCCCCCCCCCCCCC	21.07	29978859
53	Ubiquitination	SGSCPDPKCQARLFF CCCCCCCCCCEEEEE	46.49	24816145
65	Phosphorylation	LFFPASGSVSIECTE EEEECCCEEEEEEEC	15.36	27251275
67	Phosphorylation	FPASGSVSIECTECG EECCCEEEEEEECCC	17.86	27251275
111	Ubiquitination	LGVTGAPKKNTELVK HCCCCCCCCCCHHHH	59.11	29967540
112	Ubiquitination	GVTGAPKKNTELVKV CCCCCCCCCCHHHHH	68.96	23503661
114	Phosphorylation	TGAPKKNTELVKVMG CCCCCCCCHHHHHHC	39.31	29759185
118	Ubiquitination	KKNTELVKVMGLSNY CCCCHHHHHHCCCCH	38.84	23503661
125	Phosphorylation	KVMGLSNYHCKLLSP HHHCCCCHHHHHHHH	12.76	29759185
128	Ubiquitination	GLSNYHCKLLSPILA CCCCHHHHHHHHHHH	38.87	29967540
131	Phosphorylation	NYHCKLLSPILARYG CHHHHHHHHHHHHHC	21.96	28450419
137	Phosphorylation	LSPILARYGMDKQTG HHHHHHHHCCCCCCC	15.93	20068231
141	Ubiquitination	LARYGMDKQTGRAKL HHHHCCCCCCCHHHH	40.65	29967540
182	Ubiquitination	VNTVGYGKDRSGSLL CCCCCCCCCCCCCEE	41.29	21906983
185	Phosphorylation	VGYGKDRSGSLLYLH CCCCCCCCCCEEEEE	42.75	30108239
187	Phosphorylation	YGKDRSGSLLYLHDT CCCCCCCCEEEEECC	19.22	30108239
190	Phosphorylation	DRSGSLLYLHDTLED CCCCCEEEEECCHHH	13.79	23312004
194	Phosphorylation	SLLYLHDTLEDIKRA CEEEEECCHHHHHHH	22.69	23312004
199	Ubiquitination	HDTLEDIKRANKSQE ECCHHHHHHHCCCCC	58.75	30230243
203	Ubiquitination	EDIKRANKSQECLIP HHHHHHCCCCCCEEE	53.16	30230243
243	Acetylation	HALRENLKQHFQQHL HHHHHHHHHHHHHHH	53.99	19828469
314	Phosphorylation	DSLSGMRSSGDYSAT HCCCCCCCCCCCCCC	29.76	28857561
315	Phosphorylation	SLSGMRSSGDYSATF CCCCCCCCCCCCCCC	25.89	28857561
318	Phosphorylation	GMRSSGDYSATFLPG CCCCCCCCCCCCCCC	12.06	28857561
319	Phosphorylation	MRSSGDYSATFLPGL CCCCCCCCCCCCCCC	26.10	27080861
321	Phosphorylation	SSGDYSATFLPGLIP CCCCCCCCCCCCCCC	21.55	27080861
331	Ubiquitination	PGLIPAEKCTGKDGH CCCCCHHHCCCCCCC	38.92	21963094
335	Ubiquitination	PAEKCTGKDGHLNKP CHHHCCCCCCCCCCC	42.24	22817900
341	Ubiquitination	GKDGHLNKPICIAWS CCCCCCCCCEEEEEC	41.96	29967540
355	Phosphorylation	SSSGRNHYIPLVGIK CCCCCCCEEEEEEEC	14.05	27642862
362	Ubiquitination	YIPLVGIKGAALPKL EEEEEEECCCCCCCC	36.25	22505724
368	Ubiquitination	IKGAALPKLPMNLLP ECCCCCCCCCCCCCH	67.10	30230243
376	Ubiquitination	LPMNLLPKAWGVPQD CCCCCCHHHHCCCHH	57.66	22817900
386	Ubiquitination	GVPQDLIKKYIKLEE CCCHHHHHHHCCEEC	46.98	22505724
387	Ubiquitination	VPQDLIKKYIKLEED CCHHHHHHHCCEECC	45.26	23503661
390	Acetylation	DLIKKYIKLEEDGGC HHHHHHCCEECCCCE	46.91	7706123
390	Ubiquitination	DLIKKYIKLEEDGGC HHHHHHCCEECCCCE	46.91	23503661
408	Acetylation	GDRSLQDKYLLRLVA CCCHHCHHHHHHHHH	25.49	19608861
408	Ubiquitination	GDRSLQDKYLLRLVA CCCHHCHHHHHHHHH	25.49	19608861
408	Malonylation	GDRSLQDKYLLRLVA CCCHHCHHHHHHHHH	25.49	26320211
409	Phosphorylation	DRSLQDKYLLRLVAA CCHHCHHHHHHHHHH	21.18	-
458	Ubiquitination	EEVTAAAKKAVMDNR HHHHHHHHHHHHCCH	36.22	21906983
459	Ubiquitination	EVTAAAKKAVMDNRL HHHHHHHHHHHCCHH	41.30	22817900
496	Ubiquitination	GKLYNLAKSTHGQLR CHHHHHHHHCCCCCC	60.08	30230243
506	Ubiquitination	HGQLRTDKNYSFPLN CCCCCCCCCCCCCCC	58.11	29967540
509	Phosphorylation	LRTDKNYSFPLNNLV CCCCCCCCCCCCCEE	29.76	30387612
518	Phosphorylation	PLNNLVCSYDSVKDV CCCCEEECCCHHHCE	25.21	30387612
521	Phosphorylation	NLVCSYDSVKDVLVP CEEECCCHHHCEECC	23.88	30387612
533	Phosphorylation	LVPDYGMSNLTACNW ECCCCCCCCCCCCCC	25.07	27251275
536	Phosphorylation	DYGMSNLTACNWCHG CCCCCCCCCCCCCCC	33.15	27251275
544	Phosphorylation	ACNWCHGTSVRKVRG CCCCCCCCCEEEEEC	10.61	27251275
545	Phosphorylation	CNWCHGTSVRKVRGD CCCCCCCCEEEEECC	25.23	27080861
554	Phosphorylation	RKVRGDGSIVYLDGD EEEECCCCEEEEECC	17.39	28857561
557	Phosphorylation	RGDGSIVYLDGDRTN ECCCCEEEEECCCCC	9.45	28796482
563	Phosphorylation	VYLDGDRTNSRSTGG EEEECCCCCCCCCCC	42.14	23403867
571	Ubiquitination	NSRSTGGKCGCGFKH CCCCCCCCCCCCCCC	28.88	29967540
632	Ubiquitination	VAMKLVTKHFPGEFG HHHHHHHHHCCCCCC	35.45	29967540
646	Ubiquitination	GSEILVQKVVHTILH CHHHHHHHHHHHHHH	38.45	29967540
657	Ubiquitination	TILHQTAKKNPDDYT HHHHHHHHHCCCCCC	57.37	29967540
658	Ubiquitination	ILHQTAKKNPDDYTP HHHHHHHHCCCCCCC	71.85	30230243
663	Phosphorylation	AKKNPDDYTPVNIDG HHHCCCCCCCCCCCC	21.96	28796482
664	Phosphorylation	KKNPDDYTPVNIDGA HHCCCCCCCCCCCCC	27.96	28796482
691	Ubiquitination	SESQLPTKIILTGQK CCCCCCCEEEECCCC	26.30	21906983
695	Phosphorylation	LPTKIILTGQKTKTL CCCEEEECCCCCCCC	27.45	28555341
698	Ubiquitination	KIILTGQKTKTLHKE EEEECCCCCCCCCHH	54.02	27667366
698	Acetylation	KIILTGQKTKTLHKE EEEECCCCCCCCCHH	54.02	25953088
700	Ubiquitination	ILTGQKTKTLHKEEL EECCCCCCCCCHHHH	57.00	-
704	Ubiquitination	QKTKTLHKEELNMSK CCCCCCCHHHHCCCH	56.87	29967540
710	Phosphorylation	HKEELNMSKTERTIQ CHHHHCCCHHHHHHH	35.04	29214152
725	Phosphorylation	QNITEQASVMQKRKT HHHHHHHHHHHHHHH	20.16	28857561
729	Ubiquitination	EQASVMQKRKTEKLK HHHHHHHHHHHHHHH	37.45	23000965
731	Ubiquitination	ASVMQKRKTEKLKQE HHHHHHHHHHHHHHH	68.98	23000965
732	Phosphorylation	SVMQKRKTEKLKQEQ HHHHHHHHHHHHHHH	42.24	-
734	Ubiquitination	MQKRKTEKLKQEQKG HHHHHHHHHHHHHCC	67.24	23000965
736	Ubiquitination	KRKTEKLKQEQKGQP HHHHHHHHHHHCCCC	63.96	24816145
745	Phosphorylation	EQKGQPRTVSPSTIR HHCCCCCCCCCCCCC	31.83	22115753
747	Phosphorylation	KGQPRTVSPSTIRDG CCCCCCCCCCCCCCC	16.72	25159151
749	Phosphorylation	QPRTVSPSTIRDGPS CCCCCCCCCCCCCCC	29.03	25159151
750	Phosphorylation	PRTVSPSTIRDGPSS CCCCCCCCCCCCCCC	24.34	25159151
756	Phosphorylation	STIRDGPSSAPATPT CCCCCCCCCCCCCCC	44.66	30266825
757	Phosphorylation	TIRDGPSSAPATPTK CCCCCCCCCCCCCCC	41.21	29255136
761	Phosphorylation	GPSSAPATPTKAPYS CCCCCCCCCCCCCCC	30.36	29255136
763	Phosphorylation	SSAPATPTKAPYSPT CCCCCCCCCCCCCCC	35.17	27273156
764	Ubiquitination	SAPATPTKAPYSPTT CCCCCCCCCCCCCCC	48.87	27667366
767	Phosphorylation	ATPTKAPYSPTTSKE CCCCCCCCCCCCCCC	31.94	30266825
768	Phosphorylation	TPTKAPYSPTTSKEK CCCCCCCCCCCCCCC	18.08	25159151
770	Phosphorylation	TKAPYSPTTSKEKKI CCCCCCCCCCCCCEE	37.45	30266825
771	Phosphorylation	KAPYSPTTSKEKKIR CCCCCCCCCCCCEEE	40.98	30266825
772	Phosphorylation	APYSPTTSKEKKIRI CCCCCCCCCCCEEEE	41.10	30266825
773	Ubiquitination	PYSPTTSKEKKIRIT CCCCCCCCCCEEEEE	72.03	27667366
780	Phosphorylation	KEKKIRITTNDGRQS CCCEEEEECCCCCEE	15.08	26074081
781	Phosphorylation	EKKIRITTNDGRQSM CCEEEEECCCCCEEE	29.01	26074081
852	Ubiquitination	RITIEILKSKAEGGQ EEEEEEEHHHCCCCC	56.42	33845483
854	Ubiquitination	TIEILKSKAEGGQSA EEEEEHHHCCCCCCC	49.20	29967540
860	Phosphorylation	SKAEGGQSAAAHSAH HHCCCCCCCCHHCCC	24.13	29900121
865	Phosphorylation	GQSAAAHSAHTVKQE CCCCCHHCCCCCCHH	19.61	29900121
868	Phosphorylation	AAAHSAHTVKQEDIA CCHHCCCCCCHHHHH	29.16	29900121
870	Ubiquitination	AHSAHTVKQEDIAVT HHCCCCCCHHHHHHH	49.47	22817900
877	Phosphorylation	KQEDIAVTGKLSSKE CHHHHHHHCCCCHHH	21.41	29900121
879	Ubiquitination	EDIAVTGKLSSKELQ HHHHHHCCCCHHHHH	35.51	27667366
881	Phosphorylation	IAVTGKLSSKELQEQ HHHHCCCCHHHHHHH	42.73	27251275
883	Ubiquitination	VTGKLSSKELQEQAE HHCCCCHHHHHHHHH	60.10	21906983
929	Ubiquitination	GVFYSIMKKTMGMAD CHHHHHHHHHHCCCC	43.34	23503661
930	Ubiquitination	VFYSIMKKTMGMADG HHHHHHHHHHCCCCC	26.77	23503661
938	Ubiquitination	TMGMADGKHCTFPHL HHCCCCCCCCCCCCC	35.73	29967540
948	Ubiquitination	TFPHLPGKTFVYNAS CCCCCCCCEEEEECC	36.53	29967540
991	Phosphorylation	SQVRAEATTRSRESS HHHHHHHHCCCCCCC	17.78	23401153
992	Phosphorylation	QVRAEATTRSRESSP HHHHHHHCCCCCCCC	33.42	23403867
994	Phosphorylation	RAEATTRSRESSPSH HHHHHCCCCCCCCCC	38.00	22167270
997	Phosphorylation	ATTRSRESSPSHGLL HHCCCCCCCCCCCCE	46.57	22167270
997	O-linked_Glycosylation	ATTRSRESSPSHGLL HHCCCCCCCCCCCCE	46.57	28657654
998	Phosphorylation	TTRSRESSPSHGLLK HCCCCCCCCCCCCEE	26.18	22167270
1000	Phosphorylation	RSRESSPSHGLLKLG CCCCCCCCCCCEECC	31.94	30266825
1005	Ubiquitination	SPSHGLLKLGSGGVV CCCCCCEECCCCCEE	56.71	33845483
1008	Phosphorylation	HGLLKLGSGGVVKKK CCCEECCCCCEEECC	42.69	25159151
1013	Ubiquitination	LGSGGVVKKKSEQLH CCCCCEEECCHHHHC	52.67	33845483
1014	Ubiquitination	GSGGVVKKKSEQLHN CCCCEEECCHHHHCC	50.34	29967540
1015	Ubiquitination	SGGVVKKKSEQLHNV CCCEEECCHHHHCCE	54.21	33845483
1016	Phosphorylation	GGVVKKKSEQLHNVT CCEEECCHHHHCCEE	39.18	26074081
1028	Ubiquitination	NVTAFQGKGHSLGTA CEEEECCCCCCCCCC	42.54	23000965
1031	Phosphorylation	AFQGKGHSLGTASGN EECCCCCCCCCCCCC	36.84	28555341
1053	Ubiquitination	RETSVVRKHNTGTDF CCCCCEEECCCCCCC	29.60	23000965
1056	Phosphorylation	SVVRKHNTGTDFSNS CCEEECCCCCCCCCC	40.97	27251275
1058	Phosphorylation	VRKHNTGTDFSNSST EEECCCCCCCCCCCC	31.65	27251275
1061	Phosphorylation	HNTGTDFSNSSTKTE CCCCCCCCCCCCCCC	38.32	28348404
1063	Phosphorylation	TGTDFSNSSTKTEPS CCCCCCCCCCCCCCC	37.88	25849741
1064	Phosphorylation	GTDFSNSSTKTEPSV CCCCCCCCCCCCCCE	37.87	28348404
1065	Phosphorylation	TDFSNSSTKTEPSVF CCCCCCCCCCCCCEE	41.63	28348404
1066	Ubiquitination	DFSNSSTKTEPSVFT CCCCCCCCCCCCEEE	53.49	29967540
1067	Phosphorylation	FSNSSTKTEPSVFTA CCCCCCCCCCCEEEC	53.90	28348404
1070	Phosphorylation	SSTKTEPSVFTASSS CCCCCCCCEEECCCC	24.51	28555341
1073	Phosphorylation	KTEPSVFTASSSNSE CCCCCEEECCCCCCC	24.39	23186163
1075	Phosphorylation	EPSVFTASSSNSELI CCCEEECCCCCCCEE	31.10	23186163
1076	Phosphorylation	PSVFTASSSNSELIR CCEEECCCCCCCEEE	30.95	28857561
1076	O-linked_Glycosylation	PSVFTASSSNSELIR CCEEECCCCCCCEEE	30.95	28657654
1077	Phosphorylation	SVFTASSSNSELIRI CEEECCCCCCCEEEE	41.71	28857561
1079	O-linked_Glycosylation	FTASSSNSELIRIAP EECCCCCCCEEEECC	35.41	28657654
1079	Phosphorylation	FTASSSNSELIRIAP EECCCCCCCEEEECC	35.41	28857561
1091	Sulfoxidation	IAPGVVTMRDGRQLD ECCCEEECCCCCCCC	2.19	21406390
1108	Methylation	LVEAQRKKLQEMVSS HHHHHHHHHHHHHHH	58.55	-
1108	Ubiquitination	LVEAQRKKLQEMVSS HHHHHHHHHHHHHHH	58.55	29967540
1115	Phosphorylation	KLQEMVSSIQASMDR HHHHHHHHHHHHHHH	13.81	28348404
1119	Phosphorylation	MVSSIQASMDRHLRD HHHHHHHHHHHHHHC	12.58	24719451
1125	Methylation	ASMDRHLRDQSTEQS HHHHHHHHCCCCCCC	33.52	115919773
1128	Phosphorylation	DRHLRDQSTEQSPSD HHHHHCCCCCCCCCC	37.90	26055452
1129	Phosphorylation	RHLRDQSTEQSPSDL HHHHCCCCCCCCCCC	32.20	20068231
1132	Phosphorylation	RDQSTEQSPSDLPQR HCCCCCCCCCCCCCC	21.82	25159151
1134	Phosphorylation	QSTEQSPSDLPQRKT CCCCCCCCCCCCCCH	57.96	28985074
1140	Ubiquitination	PSDLPQRKTEVVSSS CCCCCCCCHHHCCCC	43.73	29967540
1141	Phosphorylation	SDLPQRKTEVVSSSA CCCCCCCHHHCCCCC	35.88	29978859
1145	Phosphorylation	QRKTEVVSSSAKSGS CCCHHHCCCCCCCCC	24.61	29978859
1146	Phosphorylation	RKTEVVSSSAKSGSL CCHHHCCCCCCCCCC	23.78	29978859
1147	Phosphorylation	KTEVVSSSAKSGSLQ CHHHCCCCCCCCCCC	32.01	29978859
1174	Phosphorylation	TENLNTETTDGCVAD CCCCCCCCCCCHHHH	28.31	26074081
1175	Phosphorylation	ENLNTETTDGCVADA CCCCCCCCCCHHHHH	24.94	26074081
1189	Phosphorylation	ALGAAFATRSKAQRG HHHHHHHHHHHHHCC	29.08	26074081
1191	Phosphorylation	GAAFATRSKAQRGNS HHHHHHHHHHHCCCC	28.17	26074081
1198	Phosphorylation	SKAQRGNSVEELEEM HHHHCCCCHHHHHHH	33.46	30278072
1207	Phosphorylation	EELEEMDSQDAEMTN HHHHHHHHHCHHHCC	28.75	23927012
1213	Phosphorylation	DSQDAEMTNTTEPMD HHHCHHHCCCCCCCC	22.40	22199227
1215	Phosphorylation	QDAEMTNTTEPMDHS HCHHHCCCCCCCCCC	24.30	22199227
1216	Phosphorylation	DAEMTNTTEPMDHS- CHHHCCCCCCCCCC-	39.91	22199227
1222	Phosphorylation	TTEPMDHS------- CCCCCCCC-------	37.34	22199227

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
761	T	Phosphorylation	Kinase	CDK1	P06493	PSP
768	S	Phosphorylation	Kinase	CDK1	P06493	PSP
1207	S	Phosphorylation	Kinase	ATM	Q13315	Uniprot

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
1207	S	Phosphorylation		32649882
Phosphorylated at Ser-1207 by ATM or ATR following induction of covalent DNA-protein cross-links (DPCs).

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VCIP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UFD1_HUMAN	UFD1L	physical	19615732
TERA_HUMAN	VCP	physical	19615732
HUWE1_HUMAN	HUWE1	physical	19615732
FAF2_HUMAN	FAF2	physical	19615732
NPL4_HUMAN	NPLOC4	physical	19615732
NSF1C_HUMAN	NSFL1C	physical	19615732
MRP9_HUMAN	ABCC12	physical	19615732
UBX2B_HUMAN	UBXN2B	physical	19615732
UBX2A_HUMAN	UBXN2A	physical	19615732
SVIP_HUMAN	SVIP	physical	19615732
WAC_HUMAN	WAC	physical	21811234
TERA_HUMAN	VCP	physical	21811234
STX5_HUMAN	STX5	physical	12473691
LARP7_HUMAN	LARP7	physical	22863883
TERA_HUMAN	VCP	physical	23500464
WAC_HUMAN	WAC	physical	23500464
UBC_HUMAN	UBC	physical	23500464
UBC_HUMAN	UBC	physical	23827681
TERA_HUMAN	VCP	physical	24163436
ZEB1_HUMAN	ZEB1	physical	29119051

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VCIP1_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-408, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1198, AND MASSSPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-747; SER-757; THR-761AND TYR-767, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-747; SER-757; THR-763;THR-770; SER-994; SER-998 AND SER-1198, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-747, AND MASSSPECTROMETRY.	15302935 [Abstract]
Ubiquitylation
Reference	PubMed
"Tryptic digestion of ubiquitin standards reveals an improved strategyfor identifying ubiquitinated proteins by mass spectrometry."; Denis N.J., Vasilescu J., Lambert J.-P., Smith J.C., Figeys D.; Proteomics 7:868-874(2007). Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-870, AND MASSSPECTROMETRY.	17370265 [Abstract]

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