TEANC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TEANC_HUMAN
• UniProt AC: Q8N8B7
• Protein Name: Transcription elongation factor A N-terminal and central domain-containing protein
• Gene Name: TCEANC
• Organism: Homo sapiens (Human).
• Sequence Length: 351
• Protein Sequence: MSDKNQIAARASLIEQLMSKRNFEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLSKWKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETLGICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDGDPESTGKRSSELLDPTTPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLRASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMTYVICNECGEQWYHSKWVCW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
170	Phosphorylation	SSELLDPTTPMRTKC CHHHCCCCCCHHHHH	43.10	-
171	Phosphorylation	SELLDPTTPMRTKCI HHHCCCCCCHHHHHH	22.07	19413330
211	Phosphorylation	EIEEHVFTLYSKNIK HHHHHHHHHHHCCHH	24.57	26437602
213	Phosphorylation	EEHVFTLYSKNIKKY HHHHHHHHHCCHHHH	17.97	26437602
214	Phosphorylation	EHVFTLYSKNIKKYK HHHHHHHHCCHHHHH	23.49	26437602
324	Phosphorylation	LPSWVRNSNPDEQMM EEHHHHCCCCCHHHE	38.89	24043423
332	Phosphorylation	NPDEQMMTYVICNEC CCCHHHEEEEEECCC	14.86	24043423
333	Phosphorylation	PDEQMMTYVICNECG CCHHHEEEEEECCCC	3.08	24043423
344	Phosphorylation	NECGEQWYHSKWVCW CCCCCCEECCCCCCC	8.91	24043423
346	Phosphorylation	CGEQWYHSKWVCW-- CCCCEECCCCCCC--	16.71	24043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TEANC_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TEANC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TEANC_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LURA1_HUMAN	LURAP1	physical	16189514
A4_HUMAN	APP	physical	21832049
FAM9B_HUMAN	FAM9B	physical	25416956
SPERT_HUMAN	SPERT	physical	25416956
EFC4A_HUMAN	CRACR2B	physical	25416956
KR107_HUMAN	KRTAP10-7	physical	25416956
BRCA1_HUMAN	BRCA1	physical	25184681
RN219_HUMAN	RNF219	physical	21516116

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.