BRCA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BRCA1_HUMAN
• UniProt AC: P38398
• Protein Name: Breast cancer type 1 susceptibility protein
• Gene Name: BRCA1
• Organism: Homo sapiens (Human).
• Sequence Length: 1863
• Subcellular Localization: Nucleus . Chromosome . Cytoplasm . Localizes at sites of DNA damage at double-strand breaks (DSBs); recruitment to DNA damage sites is mediated by ABRAXAS1 and the BRCA1-A complex (PubMed:26778126). Translocated to the cytoplasm during UV-induced apo
• Protein Description: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for normal cell cycle progression from G2 to mitosis. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional regulator. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation. Contributes to homologous recombination repair (HRR) via its direct interaction with PALB2, fine-tunes recombinational repair partly through its modulatory role in the PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage via BRCA1-mediated ubiquitination of RBBP8. Acts as a transcriptional activator. [PubMed: 20160719]
• Protein Sequence: MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKEFVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHSRETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVTFECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRGNETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDLSALRV -------CCHHHHHH	48.19	22814378
32	Sumoylation	PICLELIKEPVSTKC CHHHHHHCCCCCCCC	69.46	-
32	Ubiquitination	PICLELIKEPVSTKC CHHHHHHCCCCCCCC	69.46	-
33 (in isoform 4)	Ubiquitination	-	43.89	21890473
38	Ubiquitination	IKEPVSTKCDHIFCK HCCCCCCCCHHHHHH	30.11	-
50	Acetylation	FCKFCMLKLLNQKKG HHHHHHHHHHCCCCC	24.84	7834009
50	Ubiquitination	FCKFCMLKLLNQKKG HHHHHHHHHHCCCCC	24.84	-
50 (in isoform 1)	Ubiquitination	-	24.84	21890473
50 (in isoform 2)	Ubiquitination	-	24.84	21890473
50 (in isoform 3)	Ubiquitination	-	24.84	21890473
50 (in isoform 5)	Ubiquitination	-	24.84	21890473
50	Ubiquitination	FCKFCMLKLLNQKKG HHHHHHHHHHCCCCC	24.84	21890473
50	Ubiquitination	FCKFCMLKLLNQKKG HHHHHHHHHHCCCCC	24.84	21890473
56	Ubiquitination	LKLLNQKKGPSQCPL HHHHCCCCCCCCCCC	67.31	-
65	Ubiquitination	PSQCPLCKNDITKRS CCCCCCCCCCCHHHH	66.39	-
72	Phosphorylation	KNDITKRSLQESTRF CCCCHHHHHHHHHHH	35.64	23663014
76	Phosphorylation	TKRSLQESTRFSQLV HHHHHHHHHHHHHHH	16.36	23663014
77	Phosphorylation	KRSLQESTRFSQLVE HHHHHHHHHHHHHHH	34.67	23663014
109	Sumoylation	ANSYNFAKKENNSPE HHHHCCCCCCCCCHH	57.38	-
109	Sumoylation	ANSYNFAKKENNSPE HHHHCCCCCCCCCHH	57.38	28112733
114	Phosphorylation	FAKKENNSPEHLKDE CCCCCCCCHHHHHHH	43.16	23401153
114 (in isoform 7)	Phosphorylation	-	43.16	24719451
119	Sumoylation	NNSPEHLKDEVSIIQ CCCHHHHHHHHHHHH	54.47	-
119	Sumoylation	NNSPEHLKDEVSIIQ CCCHHHHHHHHHHHH	54.47	-
123	Phosphorylation	EHLKDEVSIIQSMGY HHHHHHHHHHHHHCH	16.36	22617229
123 (in isoform 7)	Phosphorylation	-	16.36	24719451
127	Phosphorylation	DEVSIIQSMGYRNRA HHHHHHHHHCHHHHH	12.08	23684312
130	Phosphorylation	SIIQSMGYRNRAKRL HHHHHHCHHHHHHHH	8.96	29396449
164	Phosphorylation	SNLGTVRTLRTKQRI HHCCCCEEEECCCCC	19.09	-
184	Phosphorylation	SVYIELGSDSSEDTV EEEEEECCCCCCCCC	47.12	25954137
186	Phosphorylation	YIELGSDSSEDTVNK EEEECCCCCCCCCCC	37.01	25954137
187	Phosphorylation	IELGSDSSEDTVNKA EEECCCCCCCCCCCC	44.47	25954137
190	Phosphorylation	GSDSSEDTVNKATYC CCCCCCCCCCCCCEE	23.17	25954137
208	Phosphorylation	DQELLQITPQGTRDE CHHHEECCCCCCCCC	9.15	21712546
220	Phosphorylation	RDEISLDSAKKAACE CCCCCHHHHHHHHHC	47.48	21815630
223	Ubiquitination	ISLDSAKKAACEFSE CCHHHHHHHHHCCCC	40.72	-
229	Phosphorylation	KKAACEFSETDVTNT HHHHHCCCCCCCCCC	19.79	26714015
231	Phosphorylation	AACEFSETDVTNTEH HHHCCCCCCCCCCCC	34.27	26714015
236	Phosphorylation	SETDVTNTEHHQPSN CCCCCCCCCCCCCCC	27.59	28555341
281	Phosphorylation	CGTNTHASSLQHENS CCCCCCHHHCCCCCC	24.79	11114888
294	Ubiquitination	NSSLLLTKDRMNVEK CCCEEEECCCCCHHH	43.22	-
301	Sumoylation	KDRMNVEKAEFCNKS CCCCCHHHHHHCCCC	49.27	28112733
308	Phosphorylation	KAEFCNKSKQPGLAR HHHHCCCCCCCCCCC	23.64	22817900
309	Ubiquitination	AEFCNKSKQPGLARS HHHCCCCCCCCCCCC	63.22	-
316	Phosphorylation	KQPGLARSQHNRWAG CCCCCCCCCCCCCCC	30.13	20068231
324	Phosphorylation	QHNRWAGSKETCNDR CCCCCCCCCCCCCCC	21.41	17525332
333	Phosphorylation	ETCNDRRTPSTEKKV CCCCCCCCCCCCCCC	23.61	28985074
335	Phosphorylation	CNDRRTPSTEKKVDL CCCCCCCCCCCCCCC	48.89	28122231
336	Phosphorylation	NDRRTPSTEKKVDLN CCCCCCCCCCCCCCC	53.69	28122231
339	Sumoylation	RTPSTEKKVDLNADP CCCCCCCCCCCCCCC	34.45	-
339	Sumoylation	RTPSTEKKVDLNADP CCCCCCCCCCCCCCC	34.45	28112733
345 (in isoform 3)	Phosphorylation	-	35.31	29083192
345 (in isoform 6)	Phosphorylation	-	35.31	29083192
346 (in isoform 3)	Phosphorylation	-	36.18	29083192
346 (in isoform 6)	Phosphorylation	-	36.18	29083192
347 (in isoform 3)	Phosphorylation	-	4.95	29083192
347 (in isoform 6)	Phosphorylation	-	4.95	29083192
352 (in isoform 3)	Phosphorylation	-	63.60	29083192
352 (in isoform 6)	Phosphorylation	-	63.60	29083192
353 (in isoform 3)	Phosphorylation	-	21.98	11114888
353 (in isoform 6)	Phosphorylation	-	21.98	11114888
356 (in isoform 3)	Phosphorylation	-	49.67	20068231
356 (in isoform 6)	Phosphorylation	-	49.67	20068231
357	Ubiquitination	RKEWNKQKLPCSENP CHHHHHCCCCCCCCC	56.88	-
374	Phosphorylation	TEDVPWITLNSSIQK CCCCCEEECCHHHHH	18.93	25159151
377	Phosphorylation	VPWITLNSSIQKVNE CCEEECCHHHHHHHH	31.75	25159151
378	Phosphorylation	PWITLNSSIQKVNEW CEEECCHHHHHHHHH	28.15	25159151
387	Phosphorylation	QKVNEWFSRSDELLG HHHHHHHHCCHHHCC	31.76	20068231
389	Phosphorylation	VNEWFSRSDELLGSD HHHHHHCCHHHCCCC	33.95	28450419
395	Phosphorylation	RSDELLGSDDSHDGE CCHHHCCCCCCCCCC	37.91	22167270
395 (in isoform 7)	Phosphorylation	-	37.91	24719451
398	Phosphorylation	ELLGSDDSHDGESES HHCCCCCCCCCCCHH	28.59	22167270
398 (in isoform 7)	Phosphorylation	-	28.59	24719451
403	Phosphorylation	DDSHDGESESNAKVA CCCCCCCCHHHHHHH	52.43	22167270
405	Phosphorylation	SHDGESESNAKVADV CCCCCCHHHHHHHHH	51.90	22167270
422	Phosphorylation	VLNEVDEYSGSSEKI HHHHHHHCCCCHHHC	17.54	30108239
423	Phosphorylation	LNEVDEYSGSSEKID HHHHHHCCCCHHHCC	30.10	22115753
423 (in isoform 7)	Phosphorylation	-	30.10	27251275
425	Phosphorylation	EVDEYSGSSEKIDLL HHHHCCCCHHHCCEE	29.41	22115753
426	Phosphorylation	VDEYSGSSEKIDLLA HHHCCCCHHHCCEEC	46.57	22115753
428	Ubiquitination	EYSGSSEKIDLLASD HCCCCHHHCCEECCC	43.39	-
434	Phosphorylation	EKIDLLASDPHEALI HHCCEECCCCCCEEE	52.20	30266825
434 (in isoform 7)	Phosphorylation	-	52.20	27251275
443	Sumoylation	PHEALICKSERVHSK CCCEEEECCCCCCCC	48.64	-
443	Sumoylation	PHEALICKSERVHSK CCCEEEECCCCCCCC	48.64	28112733
443	Ubiquitination	PHEALICKSERVHSK CCCEEEECCCCCCCC	48.64	-
449	Phosphorylation	CKSERVHSKSVESNI ECCCCCCCCCCCCCH	24.62	20873877
450	Ubiquitination	KSERVHSKSVESNIE CCCCCCCCCCCCCHH	43.58	-
451	Phosphorylation	SERVHSKSVESNIED CCCCCCCCCCCCHHH	33.85	21815630
451 (in isoform 7)	Phosphorylation	-	33.85	27251275
454	Phosphorylation	VHSKSVESNIEDKIF CCCCCCCCCHHHHHC	40.74	20164059
457	Ubiquitination	KSVESNIEDKIFGKT CCCCCCHHHHHCCHH	58.46	21890473
459	Sumoylation	VESNIEDKIFGKTYR CCCCHHHHHCCHHHH	27.43	-
459	Sumoylation	VESNIEDKIFGKTYR CCCCHHHHHCCHHHH	27.43	28112733
459	Ubiquitination	VESNIEDKIFGKTYR CCCCHHHHHCCHHHH	27.43	-
463	Ubiquitination	IEDKIFGKTYRKKAS HHHHHCCHHHHCCCC	31.47	-
509	Phosphorylation	LKRKRRPTSGLHPED HHHCCCCCCCCCHHH	33.35	27273156
510	Phosphorylation	KRKRRPTSGLHPEDF HHCCCCCCCCCHHHH	41.88	27273156
510 (in isoform 7)	Phosphorylation	-	41.88	24719451
519	Sumoylation	LHPEDFIKKADLAVQ CCHHHHHHHHHHHHH	41.73	28112733
519	Ubiquitination	LHPEDFIKKADLAVQ CCHHHHHHHHHHHHH	41.73	-
525 (in isoform 5)	Ubiquitination	-	8.57	21890473
528	Phosphorylation	ADLAVQKTPEMINQG HHHHHHHCHHHHHCC	13.85	28555341
549	Phosphorylation	NGQVMNITNSGHENK CCEEEECCCCCCCCC	20.51	23186163
551	Phosphorylation	QVMNITNSGHENKTK EEEECCCCCCCCCCC	32.64	30576142
564 (in isoform 3)	Ubiquitination	-	61.61	21890473
566	Ubiquitination	GDSIQNEKNPNPIES CCCCCCCCCCCHHHH	82.39	-
576	Ubiquitination	NPIESLEKESAFKTK CHHHHHHHHHHHCCC	63.36	-
583	Sumoylation	KESAFKTKAEPISSS HHHHHCCCCCCCCHH	51.87	-
583	Sumoylation	KESAFKTKAEPISSS HHHHHCCCCCCCCHH	51.87	28112733
589	Phosphorylation	TKAEPISSSISNMEL CCCCCCCHHHCCEEE	32.20	25332170
603	Phosphorylation	LELNIHNSKAPKKNR EEEEECCCCCCCCCC	18.94	25332170
615	Phosphorylation	KNRLRRKSSTRHIHA CCCCCCCCCCCCEEH	34.82	30576142
615 (in isoform 7)	Phosphorylation	-	34.82	24719451
616	Phosphorylation	NRLRRKSSTRHIHAL CCCCCCCCCCCEEHH	32.28	17525332
616 (in isoform 7)	Phosphorylation	-	32.28	24719451
617	Phosphorylation	RLRRKSSTRHIHALE CCCCCCCCCCEEHHH	33.10	22817900
628	Phosphorylation	HALELVVSRNLSPPN EHHHHHHHCCCCCCC	14.15	24719451
632	Phosphorylation	LVVSRNLSPPNCTEL HHHHCCCCCCCCCEE	41.69	27422710
632 (in isoform 7)	Phosphorylation	-	41.69	27251275
637	Phosphorylation	NLSPPNCTELQIDSC CCCCCCCCEEEEECC	46.50	22199227
643	Phosphorylation	CTELQIDSCSSSEEI CCEEEEECCCCCHHH	19.96	20873877
645	Phosphorylation	ELQIDSCSSSEEIKK EEEEECCCCCHHHHH	40.63	20873877
646	Phosphorylation	LQIDSCSSSEEIKKK EEEECCCCCHHHHHH	46.20	20873877
647	Phosphorylation	QIDSCSSSEEIKKKK EEECCCCCHHHHHHH	23.97	20068231
654	Sumoylation	SEEIKKKKYNQMPVR CHHHHHHHHCCCCCC	59.31	-
654	Sumoylation	SEEIKKKKYNQMPVR CHHHHHHHHCCCCCC	59.31	25218447
676	Phosphorylation	MEGKEPATGAKKSNK HCCCCCCCCCCCCCC	48.68	28555341
679	Acetylation	KEPATGAKKSNKPNE CCCCCCCCCCCCCCC	59.07	25953088
694	Phosphorylation	QTSKRHDSDTFPELK CHHCCCCCCCCCCEE	32.21	25159151
694 (in isoform 7)	Phosphorylation	-	32.21	24719451
696	Phosphorylation	SKRHDSDTFPELKLT HCCCCCCCCCCEEEC	45.07	28348404
701	Ubiquitination	SDTFPELKLTNAPGS CCCCCCEEECCCCCC	52.16	-
708	Phosphorylation	KLTNAPGSFTKCSNT EECCCCCCCCCCCCH	28.78	25159151
710	Phosphorylation	TNAPGSFTKCSNTSE CCCCCCCCCCCCHHH	32.60	25159151
711	Ubiquitination	NAPGSFTKCSNTSEL CCCCCCCCCCCHHHH	33.39	-
713	Phosphorylation	PGSFTKCSNTSELKE CCCCCCCCCHHHHHH	44.70	26270265
715	Phosphorylation	SFTKCSNTSELKEFV CCCCCCCHHHHHHHH	13.79	26270265
716	Phosphorylation	FTKCSNTSELKEFVN CCCCCCHHHHHHHHC	45.22	26270265
725	Phosphorylation	LKEFVNPSLPREEKE HHHHHCCCCCHHHHH	45.89	-
734	Sumoylation	PREEKEEKLETVKVS CHHHHHHHHCEEECC	53.36	-
734	Sumoylation	PREEKEEKLETVKVS CHHHHHHHHCEEECC	53.36	25218447
739	Sumoylation	EEKLETVKVSNNAED HHHHCEEECCCCCCC	47.57	-
739	Sumoylation	EEKLETVKVSNNAED HHHHCEEECCCCCCC	47.57	25218447
741	Phosphorylation	KLETVKVSNNAEDPK HHCEEECCCCCCCHH	20.74	-
748	Ubiquitination	SNNAEDPKDLMLSGE CCCCCCHHHHCCCCC	75.67	-
753	Phosphorylation	DPKDLMLSGERVLQT CHHHHCCCCCHHEEC	25.33	30266825
753 (in isoform 7)	Phosphorylation	-	25.33	24719451
763	Phosphorylation	RVLQTERSVESSSIS HHEECCCCCCCCCEE	24.81	25332170
766	Phosphorylation	QTERSVESSSISLVP ECCCCCCCCCEEECC	27.51	25332170
767	Phosphorylation	TERSVESSSISLVPG CCCCCCCCCEEECCC	20.41	25332170
775	Phosphorylation	SISLVPGTDYGTQES CEEECCCCCCCCHHH	21.70	24532841
777	Phosphorylation	SLVPGTDYGTQESIS EECCCCCCCCHHHEE	23.16	24532841
803	Phosphorylation	TEPNKCVSQCAAFEN CCCCCHHHHHHHHCC	29.07	28348404
820	Ubiquitination	GLIHGCSKDNRNDTE CCEECCCCCCCCCCC	64.20	-
830	Ubiquitination	RNDTEGFKYPLGHEV CCCCCCCCCCCCCCC	57.74	-
840	Phosphorylation	LGHEVNHSRETSIEM CCCCCCCCCCCEEEE	26.97	28985074
843	Phosphorylation	EVNHSRETSIEMEES CCCCCCCCEEEECHH	33.62	28348404
844	Phosphorylation	VNHSRETSIEMEESE CCCCCCCEEEECHHH	16.29	28348404
868	Phosphorylation	FKVSKRQSFAPFSNP HCCCCCCCCCCCCCC	27.66	-
889	Phosphorylation	CATFSAHSGSLKKQS HHHEECCCCCCCCCC	29.78	25627689
896	Phosphorylation	SGSLKKQSPKVTFEC CCCCCCCCCCEEEEE	35.25	30576142
909	N-linked_Glycosylation	ECEQKEENQGKNESN EECCHHHHCCCCCCC	57.93	19522481
909	N-linked_Glycosylation	ECEQKEENQGKNESN EECCHHHHCCCCCCC	57.93	19522481
913	N-linked_Glycosylation	KEENQGKNESNIKPV HHHHCCCCCCCCCCC	65.83	19522481
913	N-linked_Glycosylation	KEENQGKNESNIKPV HHHHCCCCCCCCCCC	65.83	19522481
916	N-linked_Glycosylation	NQGKNESNIKPVQTV HCCCCCCCCCCCEEE	39.87	19522481
916	N-linked_Glycosylation	NQGKNESNIKPVQTV HCCCCCCCCCCCEEE	39.87	19522481
918	Sumoylation	GKNESNIKPVQTVNI CCCCCCCCCCEEEEE	43.30	-
918	Sumoylation	GKNESNIKPVQTVNI CCCCCCCCCCEEEEE	43.30	28112733
950	Phosphorylation	KCSIKGGSRFCLSSQ EEEEECCCCEEECCC	30.74	30631047
955	Phosphorylation	GGSRFCLSSQFRGNE CCCCEEECCCCCCCC	24.23	23312004
956	Phosphorylation	GSRFCLSSQFRGNET CCCEEECCCCCCCCC	22.01	23312004
963	Phosphorylation	SQFRGNETGLITPNK CCCCCCCCCCCCCCC	41.09	27251275
967	Phosphorylation	GNETGLITPNKHGLL CCCCCCCCCCCCCCC	26.33	23401153
967 (in isoform 7)	Phosphorylation	-	26.33	24719451
970	Ubiquitination	TGLITPNKHGLLQNP CCCCCCCCCCCCCCC	40.01	-
970 (in isoform 4)	Ubiquitination	-	40.01	21890473
978	Phosphorylation	HGLLQNPYRIPPLFP CCCCCCCCCCCCCCC	28.82	-
987	Sumoylation	IPPLFPIKSFVKTKC CCCCCCHHHHHHHHH	37.77	28112733
987	Ubiquitination	IPPLFPIKSFVKTKC CCCCCCHHHHHHHHH	37.77	-
987 (in isoform 1)	Ubiquitination	-	37.77	21890473
987 (in isoform 2)	Ubiquitination	-	37.77	21890473
987	Ubiquitination	IPPLFPIKSFVKTKC CCCCCCHHHHHHHHH	37.77	21890473
988	Phosphorylation	PPLFPIKSFVKTKCK CCCCCHHHHHHHHHH	35.67	18987440
1007	Phosphorylation	EENFEEHSMSPEREM HHHHHHHCCCCCHHH	25.00	30266825
1009	Phosphorylation	NFEEHSMSPEREMGN HHHHHCCCCCHHHCC	26.99	30266825
1009 (in isoform 7)	Phosphorylation	-	26.99	24719451
1021	Phosphorylation	MGNENIPSTVSTISR HCCCCCCHHHHHHHH	37.33	29978859
1022	Phosphorylation	GNENIPSTVSTISRN CCCCCCHHHHHHHHC	17.08	27251275
1024	Phosphorylation	ENIPSTVSTISRNNI CCCCHHHHHHHHCCH	21.80	28555341
1050	Phosphorylation	NINEVGSSTNEVGSS CCCCCCCCHHHCCCC	29.35	-
1079	Sumoylation	LGRNRGPKLNAMLRL HHCCCCHHHHHHHHH	58.14	-
1079	Acetylation	LGRNRGPKLNAMLRL HHCCCCHHHHHHHHH	58.14	25953088
1079	Sumoylation	LGRNRGPKLNAMLRL HHCCCCHHHHHHHHH	58.14	28112733
1097	Phosphorylation	QPEVYKQSLPGSNCK CHHHHHHCCCCCCCC	32.17	28555341
1101	Phosphorylation	YKQSLPGSNCKHPEI HHHCCCCCCCCCCCH	36.80	25159151
1140	Phosphorylation	LEQPMGSSHASQVCS CCCCCCCCHHHHHCC	19.83	19651622
1143	Phosphorylation	PMGSSHASQVCSETP CCCCCHHHHHCCCCC	20.09	11114888
1149	Phosphorylation	ASQVCSETPDDLLDD HHHHCCCCCCHHCCC	18.74	20068231
1163	Phosphorylation	DGEIKEDTSFAENDI CCCCCCCCCCHHHHH	27.17	22199227
1164	Phosphorylation	GEIKEDTSFAENDIK CCCCCCCCCHHHHHH	34.48	25159151
1171	Ubiquitination	SFAENDIKESSAVFS CCHHHHHHHHHHCCC	55.17	-
1173	Phosphorylation	AENDIKESSAVFSKS HHHHHHHHHHCCCCC	20.70	28985074
1173 (in isoform 7)	Phosphorylation	-	20.70	27251275
1174	Phosphorylation	ENDIKESSAVFSKSV HHHHHHHHHCCCCCC	29.55	20363803
1178	Phosphorylation	KESSAVFSKSVQKGE HHHHHCCCCCCCCCC	19.88	29396449
1179	Ubiquitination	ESSAVFSKSVQKGEL HHHHCCCCCCCCCCC	43.09	-
1180	Phosphorylation	SSAVFSKSVQKGELS HHHCCCCCCCCCCCC	28.69	27174698
1187	Phosphorylation	SVQKGELSRSPSPFT CCCCCCCCCCCCCCC	26.81	25159151
1189	Phosphorylation	QKGELSRSPSPFTHT CCCCCCCCCCCCCHH	26.76	23401153
1189 (in isoform 7)	Phosphorylation	-	26.76	24719451
1191	Phosphorylation	GELSRSPSPFTHTHL CCCCCCCCCCCHHHH	33.61	23401153
1191 (in isoform 7)	Phosphorylation	-	33.61	24719451
1194	Phosphorylation	SRSPSPFTHTHLAQG CCCCCCCCHHHHHHH	29.28	22167270
1196	Phosphorylation	SPSPFTHTHLAQGYR CCCCCCHHHHHHHHH	18.61	27794612
1202	Phosphorylation	HTHLAQGYRRGAKKL HHHHHHHHHHHHHHH	5.76	30576142
1211	Phosphorylation	RGAKKLESSEENLSS HHHHHHHCCCHHCCC	54.19	22617229
1212	Phosphorylation	GAKKLESSEENLSSE HHHHHHCCCHHCCCC	39.28	22617229
1217	Phosphorylation	ESSEENLSSEDEELP HCCCHHCCCCCCCCH	43.17	22617229
1217 (in isoform 7)	Phosphorylation	-	43.17	24719451
1218	Phosphorylation	SSEENLSSEDEELPC CCCHHCCCCCCCCHH	52.84	22617229
1218 (in isoform 7)	Phosphorylation	-	52.84	24719451
1239	Phosphorylation	GKVNNIPSQSTRHST HCCCCCCCCCCCCHH	32.73	17525332
1239 (in isoform 7)	Phosphorylation	-	32.73	24719451
1241	Phosphorylation	VNNIPSQSTRHSTVA CCCCCCCCCCCHHHH	31.57	25159151
1242	Phosphorylation	NNIPSQSTRHSTVAT CCCCCCCCCCHHHHH	25.43	30576142
1245	Phosphorylation	PSQSTRHSTVATECL CCCCCCCHHHHHHHH	22.68	17525332
1246	Phosphorylation	SQSTRHSTVATECLS CCCCCCHHHHHHHHC	14.18	29759185
1249	Phosphorylation	TRHSTVATECLSKNT CCCHHHHHHHHCCCH	23.93	29759185
1253	Phosphorylation	TVATECLSKNTEENL HHHHHHHCCCHHHHH	35.20	25159151
1254	Ubiquitination	VATECLSKNTEENLL HHHHHHCCCHHHHHH	55.74	-
1262	Phosphorylation	NTEENLLSLKNSLND CHHHHHHHHHHHHHH	40.23	24719451
1264	Ubiquitination	EENLLSLKNSLNDCS HHHHHHHHHHHHHHC	40.91	-
1266	Phosphorylation	NLLSLKNSLNDCSNQ HHHHHHHHHHHHCCH	27.28	25159151
1271	Phosphorylation	KNSLNDCSNQVILAK HHHHHHHCCHHHHHH	32.91	23401153
1278	Ubiquitination	SNQVILAKASQEHHL CCHHHHHHHHHHHCC	45.16	-
1280	Phosphorylation	QVILAKASQEHHLSE HHHHHHHHHHHCCCC	35.08	17531442
1280 (in isoform 7)	Phosphorylation	-	35.08	27251275
1286	Phosphorylation	ASQEHHLSEETKCSA HHHHHCCCCCCCCCH	29.09	25159151
1289	Phosphorylation	EHHLSEETKCSASLF HHCCCCCCCCCHHHH	33.04	17525332
1301	Phosphorylation	SLFSSQCSELEDLTA HHHHHHCHHHHHHCC	37.26	17525332
1307	Phosphorylation	CSELEDLTANTNTQD CHHHHHHCCCCCCCC	30.13	28348404
1310	Phosphorylation	LEDLTANTNTQDPFL HHHHCCCCCCCCCCC	36.86	28348404
1312	Phosphorylation	DLTANTNTQDPFLIG HHCCCCCCCCCCCCC	32.10	28348404
1328	Phosphorylation	SKQMRHQSESQGVGL HHHHCCCCHHCCCCC	32.84	23401153
1328 (in isoform 7)	Phosphorylation	-	32.84	27251275
1330	Phosphorylation	QMRHQSESQGVGLSD HHCCCCHHCCCCCCH	37.16	17525332
1336	Phosphorylation	ESQGVGLSDKELVSD HHCCCCCCHHHCCCC	40.48	17525332
1336 (in isoform 7)	Phosphorylation	-	40.48	27251275
1342	Phosphorylation	LSDKELVSDDEERGT CCHHHCCCCHHHCCC	52.55	23401153
1387	Phosphorylation	EDCSGLSSQSDILTT CCCCCCCCHHHHHCH	38.45	11114888
1394	Phosphorylation	SQSDILTTQQRDTMQ CHHHHHCHHHHHHHH	21.18	11114888
1423	Phosphorylation	AVLEQHGSQPSNSYP HHHHHCCCCCCCCCC	36.47	15159397
1450	Phosphorylation	RNPEQSTSEKAVLTS CCCCCCCCHHHHHHC	42.20	27067055
1456	Phosphorylation	TSEKAVLTSQKSSEY CCHHHHHHCCCCCCC	23.63	28464451
1457	Phosphorylation	SEKAVLTSQKSSEYP CHHHHHHCCCCCCCC	31.30	17525332
1460	Phosphorylation	AVLTSQKSSEYPISQ HHHHCCCCCCCCCCC	22.29	25159151
1461	Phosphorylation	VLTSQKSSEYPISQN HHHCCCCCCCCCCCC	48.46	25159151
1463	Phosphorylation	TSQKSSEYPISQNPE HCCCCCCCCCCCCCC	14.07	28450419
1466	Phosphorylation	KSSEYPISQNPEGLS CCCCCCCCCCCCCCC	21.28	17525332
1473	Phosphorylation	SQNPEGLSADKFEVS CCCCCCCCCCEEEEC	45.32	21815630
1476	Ubiquitination	PEGLSADKFEVSADS CCCCCCCEEEECCCC	43.04	-
1480	Phosphorylation	SADKFEVSADSSTSK CCCEEEECCCCCCCC	21.11	28450419
1481 (in isoform 7)	Phosphorylation	-	26.36	19651622
1483	Phosphorylation	KFEVSADSSTSKNKE EEEECCCCCCCCCCC	34.92	20363803
1484	Phosphorylation	FEVSADSSTSKNKEP EEECCCCCCCCCCCC	36.93	28450419
1485	Phosphorylation	EVSADSSTSKNKEPG EECCCCCCCCCCCCC	47.90	28450419
1486	Phosphorylation	VSADSSTSKNKEPGV ECCCCCCCCCCCCCC	35.86	20363803
1496	Phosphorylation	KEPGVERSSPSKCPS CCCCCCCCCCCCCCC	32.85	30266825
1497	Phosphorylation	EPGVERSSPSKCPSL CCCCCCCCCCCCCCC	39.14	30266825
1499	Phosphorylation	GVERSSPSKCPSLDD CCCCCCCCCCCCCCC	49.16	30266825
1503	Phosphorylation	SSPSKCPSLDDRWYM CCCCCCCCCCCCCEE	54.63	30266825
1512	Phosphorylation	DDRWYMHSCSGSLQN CCCCEEECCCCCCCC	8.08	28985074
1514	Phosphorylation	RWYMHSCSGSLQNRN CCEEECCCCCCCCCC	34.14	27251275
1516	Phosphorylation	YMHSCSGSLQNRNYP EEECCCCCCCCCCCC	15.53	29449344
1518 (in isoform 7)	Phosphorylation	-	48.84	24719451
1522	Phosphorylation	GSLQNRNYPSQEELI CCCCCCCCCCHHHEE	10.87	22167270
1524	Phosphorylation	LQNRNYPSQEELIKV CCCCCCCCHHHEEEE	39.60	23401153
1535 (in isoform 7)	Phosphorylation	-	45.70	27251275
1542	Phosphorylation	EEQQLEESGPHDLTE HHHHHHHHCCCCCCC	48.53	25159151
1545 (in isoform 7)	Phosphorylation	-	46.36	24719451
1548	Phosphorylation	ESGPHDLTETSYLPR HHCCCCCCCCCCCCH	43.18	28176443
1550	Phosphorylation	GPHDLTETSYLPRQD CCCCCCCCCCCCHHH	19.89	28176443
1551	Phosphorylation	PHDLTETSYLPRQDL CCCCCCCCCCCHHHC	20.59	28450419
1552	Phosphorylation	HDLTETSYLPRQDLE CCCCCCCCCCHHHCC	28.31	30576142
1561	Phosphorylation	PRQDLEGTPYLESGI CHHHCCCCCCCCCCE	10.21	27732954
1563	Phosphorylation	QDLEGTPYLESGISL HHCCCCCCCCCCEEC	23.96	27732954
1563 (in isoform 7)	Phosphorylation	-	23.96	24719451
1566	Phosphorylation	EGTPYLESGISLFSD CCCCCCCCCEECCCC	38.54	27732954
1569	Phosphorylation	PYLESGISLFSDDPE CCCCCCEECCCCCCC	27.21	30108239
1572	Phosphorylation	ESGISLFSDDPESDP CCCEECCCCCCCCCC	46.53	30108239
1577	Phosphorylation	LFSDDPESDPSEDRA CCCCCCCCCCCCCCC	61.28	30108239
1580	Phosphorylation	DDPESDPSEDRAPES CCCCCCCCCCCCCCH	58.06	30108239
1587	Phosphorylation	SEDRAPESARVGNIP CCCCCCCHHCCCCCC	21.95	22210691
1595	Phosphorylation	ARVGNIPSSTSALKV HCCCCCCCCCCCCCC	42.31	30576142
1596	Phosphorylation	RVGNIPSSTSALKVP CCCCCCCCCCCCCCC	22.49	25159151
1597	Phosphorylation	VGNIPSSTSALKVPQ CCCCCCCCCCCCCCC	23.51	30576142
1598	Phosphorylation	GNIPSSTSALKVPQL CCCCCCCCCCCCCCC	33.29	20068231
1601	Acetylation	PSSTSALKVPQLKVA CCCCCCCCCCCCHHH	52.14	25953088
1610	Phosphorylation	PQLKVAESAQSPAAA CCCHHHHHCCCCCHH	23.13	29255136
1613	Phosphorylation	KVAESAQSPAAAHTT HHHHHCCCCCHHCCC	19.07	29255136
1619	Phosphorylation	QSPAAAHTTDTAGYN CCCCHHCCCCCCCHH	22.95	29255136
1620	Phosphorylation	SPAAAHTTDTAGYNA CCCHHCCCCCCCHHH	22.83	29255136
1622	Phosphorylation	AAAHTTDTAGYNAME CHHCCCCCCCHHHHH	21.64	28450419
1625	Phosphorylation	HTTDTAGYNAMEESV CCCCCCCHHHHHHHH	9.40	30576142
1631	Phosphorylation	GYNAMEESVSREKPE CHHHHHHHHHCCCCC	16.46	23312004
1633	Phosphorylation	NAMEESVSREKPELT HHHHHHHHCCCCCCC	43.96	23312004
1634 (in isoform 7)	Phosphorylation	-	54.53	24719451
1636	Ubiquitination	EESVSREKPELTAST HHHHHCCCCCCCCCH	42.56	-
1640	Phosphorylation	SREKPELTASTERVN HCCCCCCCCCHHHHH	19.53	23312004
1642	Phosphorylation	EKPELTASTERVNKR CCCCCCCCHHHHHHH	26.09	25159151
1643	Phosphorylation	KPELTASTERVNKRM CCCCCCCHHHHHHHH	25.91	25159151
1650 (in isoform 4)	Ubiquitination	-	3.02	21890473
1651	Phosphorylation	ERVNKRMSMVVSGLT HHHHHHHHHHHCCCC	16.68	30631047
1655	Phosphorylation	KRMSMVVSGLTPEEF HHHHHHHCCCCHHHH	19.37	26552605
1658	Phosphorylation	SMVVSGLTPEEFMLV HHHHCCCCHHHHHHH	31.98	26552605
1663 (in isoform 7)	Phosphorylation	-	2.53	27251275
1666	Phosphorylation	PEEFMLVYKFARKHH HHHHHHHHHHHHHCC	9.09	26552605
1667	Ubiquitination	EEFMLVYKFARKHHI HHHHHHHHHHHHCCE	25.68	2190698
1667 (in isoform 1)	Ubiquitination	-	25.68	21890473
1675	Phosphorylation	FARKHHITLTNLITE HHHHCCEEEEECCCC	24.15	24275569
1681	Phosphorylation	ITLTNLITEETTHVV EEEEECCCCCCEEEE	30.82	24275569
1688 (in isoform 2)	Ubiquitination	-	2.24	21890473
1690	Sumoylation	ETTHVVMKTDAEFVC CCEEEEECCCHHHHH	31.48	-
1700	Phosphorylation	AEFVCERTLKYFLGI HHHHHHHHHHHHHHH	12.81	17525332
1720	Phosphorylation	VVSYFWVTQSIKERK EEEEEEEEHHHHHHH	13.75	17525332
1777	Phosphorylation	GPFTNMPTDQLEWMV CCCCCCCHHHHHHHH	26.13	-
1790	Phosphorylation	MVQLCGASVVKELSS HHHHHCHHHHHHHHC	16.84	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
114	S	Phosphorylation	Kinase	CDK2	P24941	PSP
114	S	Phosphorylation	Kinase	CDK1	P06493	PSP
308	S	Phosphorylation	Kinase	AURA	O14965	PSP
509	T	Phosphorylation	Kinase	AKT1	P31749	PSP
509	T	Phosphorylation	Kinase	PKB_GROUP	-	PhosphoELM
509	T	Phosphorylation	Kinase	AKT-FAMILY	-	GPS
632	S	Phosphorylation	Kinase	CDK4	P11802	PSP
694	S	Phosphorylation	Kinase	AKT1	P31749	PSP
967	T	Phosphorylation	Kinase	CDK2	P24941	GPS
988	S	Phosphorylation	Kinase	CHK2	O96017	PSP
1143	S	Phosphorylation	Kinase	ATR	Q13535	Uniprot
1164	S	Phosphorylation	Kinase	PLK1	P53350	PSP
1189	S	Phosphorylation	Kinase	ATM	Q13315	PSP
1189	S	Phosphorylation	Kinase	CDK1	P06493	PSP
1191	S	Phosphorylation	Kinase	CDK1	P06493	PSP
1280	S	Phosphorylation	Kinase	ATR	Q13535	Uniprot
1330	S	Phosphorylation	Kinase	ATM	Q13315	PhosphoELM
1387	S	Phosphorylation	Kinase	ATR	Q13535	Uniprot
1387	S	Phosphorylation	Kinase	ATM	Q13315	Uniprot
1394	T	Phosphorylation	Kinase	ATR	Q13535	Uniprot
1423	S	Phosphorylation	Kinase	ATR	Q13535	Uniprot
1423	S	Phosphorylation	Kinase	ATM	Q13315	Uniprot
1457	S	Phosphorylation	Kinase	ATM	Q13315	PSP
1457	S	Phosphorylation	Kinase	ATR	Q13535	Uniprot
1466	S	Phosphorylation	Kinase	ATM	Q13315	PhosphoELM
1497	S	Phosphorylation	Kinase	CDK1	P06493	PSP
1497	S	Phosphorylation	Kinase	CDK2	P24941	PSP
1497	S	Phosphorylation	Kinase	ATM	Q13315	PSP
1524	S	Phosphorylation	Kinase	ATM	Q13315	Uniprot
1524	S	Phosphorylation	Kinase	ATR	Q13535	PSP
1542	S	Phosphorylation	Kinase	ATM	Q13315	PSP
1552	Y	Phosphorylation	Kinase	FRK	P42685	PSP
1572	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS
1572	S	Phosphorylation	Kinase	CSNK2B	-	GPS
-	K	Ubiquitination	E3 ubiquitin ligase	HERC2	O95714	PMID:20631078
-	K	Ubiquitination	E3 ubiquitin ligase	FBXO44	Q9H4M3	PMID:23086937
-	K	Ubiquitination	E3 ubiquitin ligase	SKP2	Q13309	PMID:25659039
-	K	Ubiquitination	E3 ubiquitin ligase	BARD1	Q99728	PMID:22199232
-	K	Ubiquitination	E3 ubiquitin ligase	BRCA1	P38398	PMID:12431996
-	K	Ubiquitination	E3 ubiquitin ligase	HUWE1	Q7Z6Z7	PMID:24472556

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
988	S	Phosphorylation	Phosphorylation at Ser-988 by CHEK2 regulates mitotic spindle assembly.	10724175

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BRCA1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATF1_HUMAN	ATF1	physical	10945975
MSH2_HUMAN	MSH2	physical	11498787
BARD1_HUMAN	BARD1	physical	8944023
MSH6_HUMAN	MSH6	physical	11498787
FANCJ_HUMAN	BRIP1	physical	15242590
BARD1_HUMAN	BARD1	physical	11498787
M3K3_HUMAN	MAP3K3	physical	15205325
IMA1_HUMAN	KPNA2	physical	8955125
SMCA4_HUMAN	SMARCA4	physical	15034933
SMCA2_HUMAN	SMARCA2	physical	15034933
BARD1_HUMAN	BARD1	physical	12485996
H2AX_HUMAN	H2AFX	physical	12485996
UB2D1_HUMAN	UBE2D1	physical	12485996
BARD1_HUMAN	BARD1	physical	11278247
BARD1_HUMAN	BARD1	physical	11925436
USF2_HUMAN	USF2	physical	14502648
UB2D1_HUMAN	UBE2D1	physical	12732733
MYC_HUMAN	MYC	physical	11916966
NMI_HUMAN	NMI	physical	11916966
BARD1_HUMAN	BARD1	physical	14647430
BRCA1_HUMAN	BRCA1	physical	14578343
CTCFL_HUMAN	CTCFL	physical	14578343
KIF1B_HUMAN	KIF1B	physical	14578343
MSH3_HUMAN	MSH3	physical	14578343
NCOA2_HUMAN	NCOA2	physical	14578343
NCOA3_HUMAN	NCOA3	physical	14578343
M4K4_HUMAN	MAP4K4	physical	14578343
NU153_HUMAN	NUP153	physical	14578343
CTIP_HUMAN	RBBP8	physical	14578343
DNJA3_HUMAN	DNAJA3	physical	14578343
RPB1_HUMAN	POLR2A	physical	14506230
CDK8_HUMAN	CDK8	physical	9159119
MED21_HUMAN	MED21	physical	9159119
RPB1_HUMAN	POLR2A	physical	9159119
TBG1_HUMAN	TUBG1	physical	11691781
FHL2_HUMAN	FHL2	physical	14550570
FHL2_HUMAN	FHL2	physical	14986435
ELK4_HUMAN	ELK4	physical	11313879
JUN_HUMAN	JUN	physical	12080089
BARD1_HUMAN	BARD1	physical	12732733
RB_HUMAN	RB1	physical	10518542
RAD51_HUMAN	RAD51	physical	9008167
FANCJ_HUMAN	BRIP1	physical	11877378
P53_HUMAN	TP53	physical	14710355
BLM_HUMAN	BLM	physical	10783165
MRE11_HUMAN	MRE11A	physical	10783165
NBN_HUMAN	NBN	physical	10783165
RAD50_HUMAN	RAD50	physical	10783165
HSP7C_HUMAN	HSPA8	physical	9738006
CDK16_HUMAN	CDK16	physical	9738006
CTIP_HUMAN	RBBP8	physical	10196224
ABL1_HUMAN	ABL1	physical	12024016
BRCA1_HUMAN	BRCA1	physical	11573086
BARD1_HUMAN	BARD1	physical	14638690
UB2D1_HUMAN	UBE2D1	physical	14638690
ESR1_HUMAN	ESR1	physical	11493692
MYC_HUMAN	MYC	physical	14612409
MRE11_HUMAN	MRE11A	physical	11353843
P53_HUMAN	TP53	physical	9482880
CTIP_HUMAN	RBBP8	physical	9811458
BARD1_HUMAN	BARD1	physical	14636569
RAD51_HUMAN	RAD51	physical	14636569
ESR1_HUMAN	ESR1	physical	11244506
BRCA1_HUMAN	BRCA1	physical	9525870
TBG1_HUMAN	TUBG1	physical	9789027
NCOA2_HUMAN	NCOA2	physical	11085509
BARD1_HUMAN	BARD1	physical	11504724
MRE11_HUMAN	MRE11A	physical	11504724
NBN_HUMAN	NBN	physical	11504724
RAD50_HUMAN	RAD50	physical	11504724
CSTF1_HUMAN	CSTF1	physical	11257228
CSTF2_HUMAN	CSTF2	physical	11257228
MED17_HUMAN	MED17	physical	11504724
RPB1_HUMAN	POLR2A	physical	11504724
P53_HUMAN	TP53	physical	14636569
FANCJ_HUMAN	BRIP1	physical	14576433
FANCJ_HUMAN	BRIP1	physical	14578343
RB_HUMAN	RB1	physical	11521194
RBL1_HUMAN	RBL1	physical	11521194
RBL2_HUMAN	RBL2	physical	11521194
SP1_HUMAN	SP1	physical	12706836
RPB1_HUMAN	POLR2A	physical	12955082
ESR1_HUMAN	ESR1	physical	12400015
BARD1_HUMAN	BARD1	physical	11526114
RAD50_HUMAN	RAD50	physical	10426999
UB2L3_HUMAN	UBE2L3	physical	12732733
P53_HUMAN	TP53	physical	9926942
CTIP_HUMAN	RBBP8	physical	11689934
FANCJ_HUMAN	BRIP1	physical	15133502
APLP2_HUMAN	APLP2	physical	11746496
PEG3_HUMAN	PEG3	physical	11746496
RBBP7_HUMAN	RBBP7	physical	11746496
RL31_HUMAN	RPL31	physical	11746496
WNT2B_HUMAN	WNT2B	physical	11746496
NELFB_HUMAN	NELFB	physical	11739404
ACACA_HUMAN	ACACA	physical	12360400
BARD1_HUMAN	BARD1	physical	10026184
BARD1_HUMAN	BARD1	physical	12438698
P53_HUMAN	TP53	physical	9582019
CTIP_HUMAN	RBBP8	physical	9738006
ANDR_HUMAN	AR	physical	11085509
CREB1_HUMAN	CREB1	genetic	10945975
TF65_HUMAN	RELA	physical	12700228
H32_HUMAN	HIST2H3C	physical	12419249
H2AY_HUMAN	H2AFY	physical	12419249
AKT1_HUMAN	AKT1	physical	10542266
UBE3A_HUMAN	UBE3A	physical	12890688
ATM_HUMAN	ATM	physical	10783165
BARD1_HUMAN	BARD1	physical	15159397
BARD1_HUMAN	BARD1	physical	11573085
BARD1_HUMAN	BARD1	physical	9738006
BARD1_HUMAN	BARD1	physical	9342365
BARD1_HUMAN	BARD1	physical	10635334
BRCA2_HUMAN	BRCA2	physical	14636569
CBP_HUMAN	CREBBP	physical	12700228
CSTF2_HUMAN	CSTF2	physical	10477523
CTBP1_HUMAN	CTBP1	physical	10196224
ETS1_HUMAN	ETS1	physical	11313879
FLI1_HUMAN	FLI1	physical	11313879
LMO4_HUMAN	LMO4	physical	11751867
LMO4_HUMAN	LMO4	genetic	11751867
MLH1_HUMAN	MLH1	physical	10783165
MRE11_HUMAN	MRE11A	physical	10426999
MSH2_HUMAN	MSH2	physical	10783165
MSH3_HUMAN	MSH3	physical	11498787
MSH6_HUMAN	MSH6	physical	10783165
NBN_HUMAN	NBN	physical	10426999
NUFP1_HUMAN	NUFIP1	physical	15107825
RAD51_HUMAN	RAD51	physical	11498787
RFC1_HUMAN	RFC1	physical	10783165
T2EA_HUMAN	GTF2E1	physical	9159119
T2FA_HUMAN	GTF2F1	physical	9159119
TF2H4_HUMAN	GTF2H4	physical	9159119
UB2D1_HUMAN	UBE2D1	physical	14636569
UB2D1_HUMAN	UBE2D1	physical	12890688
UB2D1_HUMAN	UBE2D1	physical	11278247
CLSPN_HUMAN	CLSPN	physical	15096610
BARD1_HUMAN	BARD1	physical	12951069
HDAC1_HUMAN	HDAC1	physical	10220405
HDAC2_HUMAN	HDAC2	physical	10220405
SMCA4_HUMAN	SMARCA4	physical	10943845
SMRC2_HUMAN	SMARCC2	physical	10943845
SMRC1_HUMAN	SMARCC1	physical	10943845
SMRD2_HUMAN	SMARCD2	physical	10943845
SNF5_HUMAN	SMARCB1	physical	10943845
CSK2B_HUMAN	CSNK2B	physical	10403822
EP300_HUMAN	EP300	physical	10655477
CBP_HUMAN	CREBBP	genetic	11782371
EP300_HUMAN	EP300	genetic	11782371
EP300_HUMAN	EP300	physical	11782371
CBP_HUMAN	CREBBP	physical	11782371
ESR1_HUMAN	ESR1	physical	11782371
DHH1_YEAST	DHH1	genetic	18197258
CCR4_YEAST	CCR4	genetic	18197258
DEF1_YEAST	DEF1	genetic	18197258
SPT4_YEAST	SPT4	genetic	18197258
SPT5_YEAST	SPT5	genetic	18197258
SUB1_YEAST	SUB1	genetic	18197258
MLP2_YEAST	MLP2	genetic	18197258
NUP59_YEAST	ASM4	genetic	18197258
NUP2_YEAST	NUP2	genetic	18197258
NU120_YEAST	NUP120	genetic	18197258
NU133_YEAST	NUP133	genetic	18197258
NU170_YEAST	NUP170	genetic	18197258
NU188_YEAST	NUP188	genetic	18197258
POM34_YEAST	POM34	genetic	18197258
RM39_YEAST	MRPL39	genetic	18197258
BRCA2_HUMAN	BRCA2	physical	9774970
RAD51_HUMAN	RAD51	physical	9774970
JAK1_HUMAN	JAK1	physical	11163768
JAK2_HUMAN	JAK2	physical	11163768
STA5A_HUMAN	STAT5A	physical	12459499
TERA_HUMAN	VCP	physical	10855792
CTIP_HUMAN	RBBP8	physical	10764811
FANCA_HUMAN	FANCA	physical	12354784
CCNE1_HUMAN	CCNE1	physical	17525332
CDK2_HUMAN	CDK2	physical	9244350
CDK4_HUMAN	CDK4	physical	9244350
E2F4_HUMAN	E2F4	physical	9244350
CDK1_HUMAN	CDK1	physical	9244350
CCNB1_HUMAN	CCNB1	physical	9244350
CCND1_HUMAN	CCND1	physical	9244350
BARD1_HUMAN	BARD1	physical	11301010
BACH1_HUMAN	BACH1	physical	11301010
STAT1_HUMAN	STAT1	physical	10792030
NFYA_HUMAN	NFYA	physical	11777930
PO2F1_HUMAN	POU2F1	physical	11777930
DHX9_HUMAN	DHX9	physical	9662397
BRAP_HUMAN	BRAP	physical	9497340
ZN350_HUMAN	ZNF350	physical	11090615
MYC_HUMAN	MYC	physical	9788437
ANDR_HUMAN	AR	physical	11016951
BARD1_HUMAN	BARD1	physical	19176389
BARD1_HUMAN	BARD1	physical	19117993
AKT1_HUMAN	AKT1	physical	19074868
CHK2_HUMAN	CHEK2	physical	18804494
BRAP_HUMAN	BRAP	physical	8955125
UIMC1_HUMAN	UIMC1	physical	17525342
CTIP_HUMAN	RBBP8	physical	17525342
FANCJ_HUMAN	BRIP1	physical	17525342
UIMC1_HUMAN	UIMC1	physical	17525341
FANCJ_HUMAN	BRIP1	physical	17525341
PP1B_HUMAN	PPP1CB	physical	17511879
ATM_HUMAN	ATM	physical	17478428
ATR_HUMAN	ATR	physical	17478428
BARD1_HUMAN	BARD1	physical	20215511
MYC_HUMAN	MYC	physical	20215511
BRD7_HUMAN	BRD7	physical	20215511
CTIP_HUMAN	RBBP8	physical	16818604
BARD1_HUMAN	BARD1	physical	16489000
ACACA_HUMAN	ACACA	physical	16326698
PIAS4_HUMAN	PIAS4	physical	20016603
PIAS1_HUMAN	PIAS1	physical	20016603
SUMO1_HUMAN	SUMO1	physical	20016594
UBC9_HUMAN	UBE2I	physical	20016594
PIAS1_HUMAN	PIAS1	physical	20016594
PIAS4_HUMAN	PIAS4	physical	20016594
TOP2A_HUMAN	TOP2A	physical	15965487
TERF1_HUMAN	TERF1	physical	19797051
TERF2_HUMAN	TERF2	physical	19797051
RPB1_HUMAN	POLR2A	physical	15886201
BARD1_HUMAN	BARD1	physical	18936166
NCOA3_HUMAN	NCOA3	physical	16860316
BRCA1_HUMAN	BRCA1	physical	16818604
TBG1_HUMAN	TUBG1	physical	15367667
ARNT_HUMAN	ARNT	physical	16567799
TP53B_HUMAN	TP53BP1	physical	12364621
ESR1_HUMAN	ESR1	physical	16061635
MSH2_HUMAN	MSH2	physical	15886699
FACD2_HUMAN	FANCD2	physical	12887909
SMAD3_HUMAN	SMAD3	physical	15735739
RFA1_HUMAN	RPA1	physical	21240188
MLH1_HUMAN	MLH1	physical	21240188
FANCA_HUMAN	FANCA	physical	21240188
BRCA2_HUMAN	BRCA2	physical	21135251
SUMO1_HUMAN	SUMO1	physical	18025037
PO2F1_HUMAN	POU2F1	physical	18000219
BRCA2_HUMAN	BRCA2	physical	17664283
BARD1_HUMAN	BARD1	physical	17664283
BACH1_HUMAN	BACH1	physical	17664283
CDN2D_HUMAN	CDKN2D	physical	17334399
PALB2_HUMAN	PALB2	physical	19268590
BACH1_HUMAN	BACH1	physical	15125843
FACD2_HUMAN	FANCD2	physical	11239454
MDC1_HUMAN	MDC1	physical	21622030
UIMC1_HUMAN	UIMC1	physical	21622030
UB2D2_HUMAN	UBE2D2	physical	21113135
UB2D3_HUMAN	UBE2D3	physical	21113135
UB2D3_HUMAN	UBE2D3	physical	16628214
ESR1_HUMAN	ESR1	physical	20060929
BARD1_HUMAN	BARD1	physical	20060929
HERC2_HUMAN	HERC2	physical	20631078
BABA1_HUMAN	BABAM1	physical	19261746
RPAB3_HUMAN	POLR2H	physical	17283126
PRGR_HUMAN	PGR	physical	21531767
TOPB1_HUMAN	TOPBP1	physical	16391231
MRE11_HUMAN	MRE11A	physical	16391231
BACH1_HUMAN	BACH1	physical	16391231
UIMC1_HUMAN	UIMC1	physical	19261748
ESR1_HUMAN	ESR1	physical	19887647
EP300_HUMAN	EP300	physical	19887647
BRCA1_HUMAN	BRCA1	physical	20351172
BRCA1_HUMAN	BRCA1	physical	21965653
BARD1_HUMAN	BARD1	physical	21901007
TBB5_HUMAN	TUBB	physical	12353262
UB2D1_HUMAN	UBE2D1	physical	19712108
UB2D2_HUMAN	UBE2D2	physical	19712108
UB2D3_HUMAN	UBE2D3	physical	19712108
UB2E1_HUMAN	UBE2E1	physical	19712108
UB2E2_HUMAN	UBE2E2	physical	19712108
UB2E3_HUMAN	UBE2E3	physical	19712108
UB2L3_HUMAN	UBE2L3	physical	19712108
UBE2W_HUMAN	UBE2W	physical	19712108
UBE2K_HUMAN	UBE2K	physical	19712108
UBE2N_HUMAN	UBE2N	physical	19712108
UB2E1_HUMAN	UBE2E1	physical	17873885
UB2E2_HUMAN	UBE2E2	physical	17873885
UB2E3_HUMAN	UBE2E3	physical	17873885
UBE2N_HUMAN	UBE2N	physical	17873885
UBE2K_HUMAN	UBE2K	physical	17873885
UBE2W_HUMAN	UBE2W	physical	17873885
HDAC2_HUMAN	HDAC2	physical	21946536
CTIP_HUMAN	RBBP8	physical	21908405
TF65_HUMAN	RELA	physical	21908405
BARD1_HUMAN	BARD1	physical	11927591
H2A2C_HUMAN	HIST2H2AC	physical	11927591
BRCA1_HUMAN	BRCA1	physical	11927591
MDC1_HUMAN	MDC1	physical	12607005
BARD1_HUMAN	BARD1	physical	19369211
PALB2_HUMAN	PALB2	physical	19369211
BRCA2_HUMAN	BRCA2	physical	19369211
BACH1_HUMAN	BACH1	physical	19369211
BRCA1_HUMAN	BRCA1	physical	21880590
E2F1_HUMAN	E2F1	physical	21880590
PAX2_HUMAN	PAX2	physical	21880590
ZBT14_HUMAN	ZBTB14	physical	21880590
AP2A1_HUMAN	AP2A1	physical	21880590
BABA1_HUMAN	BABAM1	physical	22792303
P63_HUMAN	TP63	physical	21363924
AP2A_HUMAN	TFAP2A	physical	21363924
AP2C_HUMAN	TFAP2C	physical	21363924
P53_HUMAN	TP53	physical	16677609
ABRX1_HUMAN	FAM175A	physical	17525340
BACH1_HUMAN	BACH1	physical	17525340
CTIP_HUMAN	RBBP8	physical	17525340
UIMC1_HUMAN	UIMC1	physical	17525340
BARD1_HUMAN	BARD1	physical	20681793
FANCJ_HUMAN	BRIP1	physical	20681793
ABRX1_HUMAN	FAM175A	physical	17643121
UBC9_HUMAN	UBE2I	physical	19287951
BRCA1_HUMAN	BRCA1	physical	16403807
ETV5_HUMAN	ETV5	physical	21282464
EZRI_HUMAN	EZR	physical	21282464
RADI_HUMAN	RDX	physical	21282464
MOES_HUMAN	MSN	physical	21282464
CLSPN_HUMAN	CLSPN	physical	22863316
UIMC1_HUMAN	UIMC1	physical	19305427
ABRX1_HUMAN	FAM175A	physical	19305427
BRCC3_HUMAN	BRCC3	physical	19305427
TBG1_HUMAN	TUBG1	physical	22262852
FANCJ_HUMAN	BRIP1	physical	18717574
ERCC6_HUMAN	ERCC6	physical	21756275
ACACA_HUMAN	ACACA	physical	19061860
CHK1_HUMAN	CHEK1	physical	11836499
CTIP_HUMAN	RBBP8	physical	16843262
ZN350_HUMAN	ZNF350	physical	16843262
ESR1_HUMAN	ESR1	physical	15674350
CCAR2_HUMAN	CCAR2	physical	20160719
BARD1_HUMAN	BARD1	physical	19766185
ABRX1_HUMAN	FAM175A	physical	19766185
UIMC1_HUMAN	UIMC1	physical	19766185
H2AX_HUMAN	H2AFX	physical	19766185
MDC1_HUMAN	MDC1	physical	19766185
RAD51_HUMAN	RAD51	physical	19766185
RFA1_HUMAN	RPA1	physical	19766185
TOPB1_HUMAN	TOPBP1	physical	19766185
ATRIP_HUMAN	ATRIP	physical	17616665
BRAT1_HUMAN	BRAT1	physical	16452482
HMMR_HUMAN	HMMR	physical	22110403
TPX2_HUMAN	TPX2	physical	22110403
AURKA_HUMAN	AURKA	physical	22110403
P73_HUMAN	TP73	physical	20807817
PAF15_HUMAN	KIAA0101	physical	21673012
PP1A_HUMAN	PPP1CA	physical	12438214
BCL2_HUMAN	BCL2	physical	21444675
SMAD3_HUMAN	SMAD3	physical	19768112
FANCJ_HUMAN	BRIP1	physical	19452558
CTIP_HUMAN	RBBP8	physical	19452558
ACACA_HUMAN	ACACA	physical	18452305
FANCJ_HUMAN	BRIP1	physical	18285836
CTIP_HUMAN	RBBP8	physical	18285836
SRSF1_HUMAN	SRSF1	physical	18391021
TADBP_HUMAN	TARDBP	physical	18391021
ROA1_HUMAN	HNRNPA1	physical	18391021
ROA2_HUMAN	HNRNPA2B1	physical	18391021
DAZP1_HUMAN	DAZAP1	physical	18391021
ACACA_HUMAN	ACACA	physical	16698035
HIF1A_HUMAN	HIF1A	physical	16543242
P53_HUMAN	TP53	physical	16969499
ESR1_HUMAN	ESR1	physical	17505062
AURKA_HUMAN	AURKA	physical	14990569
BACH1_HUMAN	BACH1	physical	15242590
AHR_HUMAN	AHR	physical	18259752
JUNB_HUMAN	JUNB	physical	18259752
P53_HUMAN	TP53	physical	15571721
CTIP_HUMAN	RBBP8	physical	10910365
NINL_HUMAN	NINL	physical	19509300
BRCA1_HUMAN	BRCA1	physical	15448696
SP1_HUMAN	SP1	physical	17766039
BARD1_HUMAN	BARD1	physical	15569676
MDC1_HUMAN	MDC1	physical	15569676
GTF2I_HUMAN	GTF2I	physical	21407215
CTIP_HUMAN	RBBP8	physical	18171670
NBN_HUMAN	NBN	physical	18171670
RAD50_HUMAN	RAD50	physical	18171670
PABP1_HUMAN	PABPC1	physical	16782705
MYC_HUMAN	MYC	physical	12646176
ABRX1_HUMAN	FAM175A	physical	17643122
ATR_HUMAN	ATR	physical	11278964
PRGR_HUMAN	PGR	physical	16109739
MK03_HUMAN	MAPK3	physical	18593910
MK01_HUMAN	MAPK1	physical	18593910
IF16_HUMAN	IFI16	physical	14654789
BARD1_HUMAN	BARD1	physical	15855157
BARD1_HUMAN	BARD1	physical	18493658
FANCJ_HUMAN	BRIP1	physical	20159462
CTNB1_HUMAN	CTNNB1	physical	20215423
BARD1_HUMAN	BARD1	physical	19916563
H2A2C_HUMAN	HIST2H2AC	physical	19916563
BAP1_HUMAN	BAP1	physical	9528852
BAP1_MOUSE	Bap1	physical	9528852
CDN2A_HUMAN	CDKN2A	physical	18703154
ARF_HUMAN	CDKN2A	physical	18703154
H2AX_HUMAN	H2AFX	physical	20681793
UB2D3_HUMAN	UBE2D3	physical	21531767
UB2D3_HUMAN	UBE2D3	physical	20351172
UB2D1_HUMAN	UBE2D1	physical	12887909
UB2D3_HUMAN	UBE2D3	physical	16818604
UB2D3_HUMAN	UBE2D3	physical	15886201
UB2D1_HUMAN	UBE2D1	physical	16403807
UB2D3_HUMAN	UBE2D3	physical	22863316
UB2D3_HUMAN	UBE2D3	physical	15367667
UB2D3_HUMAN	UBE2D3	physical	21756275
UB2D3_HUMAN	UBE2D3	physical	17283126
UB2D3_HUMAN	UBE2D3	physical	21965653
UB2E1_HUMAN	UBE2E1	physical	21965653
UB2E2_HUMAN	UBE2E2	physical	21965653
UB2E3_HUMAN	UBE2E3	physical	21965653
UBE2N_HUMAN	UBE2N	physical	21965653
UBE2W_HUMAN	UBE2W	physical	21965653
SKP1_HUMAN	SKP1	physical	23086937
BARD1_HUMAN	BARD1	physical	23086937
FBX44_HUMAN	FBXO44	physical	23086937
SKP2_HUMAN	SKP2	physical	23086937
FBX5_HUMAN	FBXO5	physical	23086937
RICTR_HUMAN	RICTOR	physical	22990118
MTOR_HUMAN	MTOR	physical	22990118
ACTG_HUMAN	ACTG1	physical	22990118
AL9A1_HUMAN	ALDH9A1	physical	22990118
AT1B1_HUMAN	ATP1B1	physical	22990118
AT1B3_HUMAN	ATP1B3	physical	22990118
CDK9_HUMAN	CDK9	physical	22990118
CO1A1_HUMAN	COL1A1	physical	22990118
PGS2_HUMAN	DCN	physical	22990118
DYHC1_HUMAN	DYNC1H1	physical	22990118
IF4A2_HUMAN	EIF4A2	physical	22990118
ENOA_HUMAN	ENO1	physical	22990118
DNJA1_HUMAN	DNAJA1	physical	22990118
DNJB1_HUMAN	DNAJB1	physical	22990118
INPP_HUMAN	INPP1	physical	22990118
LDHC_HUMAN	LDHC	physical	22990118
MA2C1_HUMAN	MAN2C1	physical	22990118
M3K1_HUMAN	MAP3K1	physical	22990118
NU1M_HUMAN	ND1	physical	22990118
2A5G_HUMAN	PPP2R5C	physical	22990118
PPCE_HUMAN	PREP	physical	22990118
SAP_HUMAN	PSAP	physical	22990118
PSA6_HUMAN	PSMA6	physical	22990118
SSFA2_HUMAN	SSFA2	physical	22990118
AURKC_HUMAN	AURKC	physical	22990118
SYTC_HUMAN	TARS	physical	22990118
TLE4_HUMAN	TLE4	physical	22990118
TULP2_HUMAN	TULP2	physical	22990118
USH2A_HUMAN	USH2A	physical	22990118
ZSC21_HUMAN	ZSCAN21	physical	22990118
CUBN_HUMAN	CUBN	physical	22990118
PSMG1_HUMAN	PSMG1	physical	22990118
EIF3B_HUMAN	EIF3B	physical	22990118
SNX3_HUMAN	SNX3	physical	22990118
ASH2L_HUMAN	ASH2L	physical	22990118
UBP2_HUMAN	USP2	physical	22990118
TF3C4_HUMAN	GTF3C4	physical	22990118
IF2P_HUMAN	EIF5B	physical	22990118
TATD2_HUMAN	TATDN2	physical	22990118
QORL1_HUMAN	CRYZL1	physical	22990118
RANB9_HUMAN	RANBP9	physical	22990118
NPC2_HUMAN	NPC2	physical	22990118
DBF4A_HUMAN	DBF4	physical	22990118
SOX30_HUMAN	SOX30	physical	22990118
3HIDH_HUMAN	HIBADH	physical	22990118
WDR6_HUMAN	WDR6	physical	22990118
U520_HUMAN	SNRNP200	physical	22990118
KDM1A_HUMAN	KDM1A	physical	22990118
PISD_HUMAN	PISD	physical	22990118
CNRP1_HUMAN	CNRIP1	physical	22990118
CABYR_HUMAN	CABYR	physical	22990118
PILRB_HUMAN	PILRB	physical	22990118
HSP7E_HUMAN	HSPA14	physical	22990118
LCMT1_HUMAN	LCMT1	physical	22990118
PPHLN_HUMAN	PPHLN1	physical	22990118
RN216_HUMAN	RNF216	physical	22990118
SDK2_HUMAN	SDK2	physical	22990118
Z280D_HUMAN	ZNF280D	physical	22990118
CNTLN_HUMAN	CNTLN	physical	22990118
DALD3_HUMAN	DALRD3	physical	22990118
ERO1B_HUMAN	ERO1LB	physical	22990118
DDX24_HUMAN	DDX24	physical	22990118
RPGR1_HUMAN	RPGRIP1	physical	22990118
PHF12_HUMAN	PHF12	physical	22990118
SNX6_HUMAN	SNX6	physical	22990118
HECD3_HUMAN	HECTD3	physical	22990118
ITIH5_HUMAN	ITIH5	physical	22990118
RCC1L_HUMAN	WBSCR16	physical	22990118
TX101_HUMAN	TEX101	physical	22990118
THOC3_HUMAN	THOC3	physical	22990118
TPTE2_HUMAN	TPTE2	physical	22990118
SPAT4_HUMAN	SPATA4	physical	22990118
DNHD1_HUMAN	DNHD1	physical	22990118
COMD1_HUMAN	COMMD1	physical	22990118
CNTN4_HUMAN	CNTN4	physical	22990118
GGN_HUMAN	GGN	physical	22990118
RWDD4_HUMAN	RWDD4	physical	22990118
RTKN2_HUMAN	RTKN2	physical	22990118
NKAPL_HUMAN	NKAPL	physical	22990118
TC1D2_HUMAN	TCTEX1D2	physical	22990118
SEN54_HUMAN	TSEN54	physical	22990118
CRPAK_HUMAN	CRIPAK	physical	22990118
CAPZB_HUMAN	CAPZB	physical	22990118
FLNA_HUMAN	FLNA	physical	22990118
XRCC6_HUMAN	XRCC6	physical	22990118
DRG1_HUMAN	DRG1	physical	22990118
YBOX1_HUMAN	YBX1	physical	22990118
CDK16_HUMAN	CDK16	physical	22990118
RPB1_HUMAN	POLR2A	physical	22990118
RPB3_HUMAN	POLR2C	physical	22990118
RPB4_HUMAN	POLR2D	physical	22990118
RPAB1_HUMAN	POLR2E	physical	22990118
RPB7_HUMAN	POLR2G	physical	22990118
RPB9_HUMAN	POLR2I	physical	22990118
RPB11_HUMAN	POLR2J	physical	22990118
PP1A_HUMAN	PPP1CA	physical	22990118
PP2AA_HUMAN	PPP2CA	physical	22990118
PPP6_HUMAN	PPP6C	physical	22990118
RFC2_HUMAN	RFC2	physical	22990118
SRSF1_HUMAN	SRSF1	physical	22990118
STRN_HUMAN	STRN	physical	22990118
SPT6H_HUMAN	SUPT6H	physical	22990118
TPM1_HUMAN	TPM1	physical	22990118
TPM3_HUMAN	TPM3	physical	22990118
1433Z_HUMAN	YWHAZ	physical	22990118
MCE1_HUMAN	RNGTT	physical	22990118
RECQ5_HUMAN	RECQL5	physical	22990118
BABA2_HUMAN	BRE	physical	22990118
RACK1_HUMAN	GNB2L1	physical	22990118
ML12A_HUMAN	MYL12A	physical	22990118
FR1OP_HUMAN	FGFR1OP	physical	22990118
COPE_HUMAN	COPE	physical	22990118
GPN1_HUMAN	GPN1	physical	22990118
PHB2_HUMAN	PHB2	physical	22990118
ANR26_HUMAN	ANKRD26	physical	22990118
PP6R1_HUMAN	PPP6R1	physical	22990118
ANR28_HUMAN	ANKRD28	physical	22990118
ZDHC5_HUMAN	ZDHHC5	physical	22990118
MRM2_HUMAN	FTSJ2	physical	22990118
GPN3_HUMAN	GPN3	physical	22990118
RPR1A_HUMAN	RPRD1A	physical	22990118
PP6R3_HUMAN	PPP6R3	physical	22990118
CARF_HUMAN	CDKN2AIP	physical	22990118
PRR5_HUMAN	PRR5	physical	22990118
RPR1B_HUMAN	RPRD1B	physical	22990118
SIN1_HUMAN	MAPKAP1	physical	22990118
BRCC3_HUMAN	BRCC3	physical	22990118
RPAP3_HUMAN	RPAP3	physical	22990118
BORA_HUMAN	BORA	physical	22990118
RPAP2_HUMAN	RPAP2	physical	22990118
MYZAP_HUMAN	POLR2M	physical	22990118
GRL1A_HUMAN	POLR2M	physical	22990118
GL1AD_HUMAN	POLR2M	physical	22990118
NEB2_HUMAN	PPP1R9B	physical	22990118
ANR44_HUMAN	ANKRD44	physical	22990118
PPR18_HUMAN	PPP1R18	physical	22990118
CE350_HUMAN	CEP350	physical	22990118
FLII_HUMAN	FLII	physical	22990118
TBG1_HUMAN	TUBG1	physical	22833046
GATA3_HUMAN	GATA3	physical	22120723
XIAP_HUMAN	XIAP	physical	16322207
CASP9_HUMAN	CASP9	physical	16322207
PABP1_HUMAN	PABPC1	physical	23805307
IF4G1_HUMAN	EIF4G1	physical	23805307
LONF1_HUMAN	LONRF1	physical	22493164
RAD18_HUMAN	RAD18	physical	23901102
RFA1_HUMAN	RPA1	physical	23901102
ATR_HUMAN	ATR	physical	23901102
TOPB1_HUMAN	TOPBP1	physical	23901102
MATK_HUMAN	MATK	physical	23901102
CH60_HUMAN	HSPD1	physical	21988832
ZEP1_HUMAN	HIVEP1	physical	21988832
PMGT1_HUMAN	POMGNT1	physical	21988832
FHL2_HUMAN	FHL2	physical	21988832
PLAK_HUMAN	JUP	physical	21988832
PEX5_HUMAN	PEX5	physical	21988832
TIF1A_HUMAN	TRIM24	physical	21988832
NF2L2_HUMAN	NFE2L2	physical	23857982
HUWE1_HUMAN	HUWE1	physical	24342616
UB2D1_HUMAN	UBE2D1	physical	24507701
BRCA1_HUMAN	BRCA1	physical	12438698
UB2D3_HUMAN	UBE2D3	physical	12438698
BARD1_HUMAN	BARD1	physical	24695549
UB2D3_HUMAN	UBE2D3	physical	15905410
UB2D3_HUMAN	UBE2D3	physical	17349954
MRE11_HUMAN	MRE11A	physical	17349954
UBC_HUMAN	UBC	physical	17349954
EZH2_HUMAN	EZH2	physical	23624935
SUZ12_HUMAN	SUZ12	physical	23624935
EED_HUMAN	EED	physical	23624935
XRCC5_HUMAN	XRCC5	physical	23344954
BRCA1_HUMAN	BRCA1	physical	21532592
UB2D3_HUMAN	UBE2D3	physical	21532592
ABRX1_HUMAN	FAM175A	physical	23416467
CTIP_HUMAN	RBBP8	physical	23416467
BARD1_HUMAN	BARD1	physical	23416467
HS90A_HUMAN	HSP90AA1	physical	24085845
RAD51_HUMAN	RAD51	physical	24085845
BARD1_HUMAN	BARD1	physical	24085845
PALB2_HUMAN	PALB2	physical	24085845
BRCA2_HUMAN	BRCA2	physical	24085845
CTIP_HUMAN	RBBP8	physical	24085845
UIMC1_HUMAN	UIMC1	physical	24085845
OLA1_HUMAN	OLA1	physical	24289923
BARD1_HUMAN	BARD1	physical	24289923
TBG1_HUMAN	TUBG1	physical	24289923
ATRIP_HUMAN	ATRIP	physical	24073851
BRAT1_HUMAN	BRAT1	physical	24073851
PP1A_HUMAN	PPP1CA	physical	25056273
XRS2_YEAST	XRS2	genetic	18197258
RAD55_YEAST	RAD55	genetic	18197258
RAD51_YEAST	RAD51	genetic	18197258
RAD50_YEAST	RAD50	genetic	18197258
BUR2_YEAST	BUR2	genetic	18197258
DENR_YEAST	TMA22	genetic	18197258
YG21_YEAST	YGR053C	genetic	18197258
YAP3_YEAST	YAP3	genetic	18197258
AF9_YEAST	YAF9	genetic	18197258
TYSY_YEAST	CDC21	genetic	18197258
NPR1_YEAST	NPR1	genetic	18197258
BEM4_YEAST	BEM4	genetic	18197258
HDA3_YEAST	HDA3	genetic	18197258
DAN1_YEAST	DAN1	genetic	18197258
GYP5_YEAST	GYP5	genetic	18197258
BBC1_YEAST	BBC1	genetic	18197258
ATE1_YEAST	ATE1	genetic	18197258
CTK1_YEAST	CTK1	genetic	18197258
MET18_YEAST	MET18	genetic	18197258
MLP1_YEAST	MLP1	genetic	18197258
NUP53_YEAST	NUP53	genetic	18197258
RAD16_YEAST	RAD16	genetic	18197258
RPB4_YEAST	RPB4	genetic	18197258
SLI15_YEAST	SLI15	genetic	18197258
SSN3_YEAST	SSN3	genetic	18197258
YBP2_YEAST	YBP2	genetic	18197258
SPT4_YEAST	SPT4	physical	18197258
SPT5H_HUMAN	SUPT5H	physical	18197258
RPB1_HUMAN	POLR2A	physical	18197258
UB2D3_HUMAN	UBE2D3	physical	25355358
BARD1_HUMAN	BARD1	physical	25184681
BRCA1_HUMAN	BRCA1	physical	25184681
BRCC3_HUMAN	BRCC3	physical	25184681
BABA2_HUMAN	BRE	physical	25184681
FANCJ_HUMAN	BRIP1	physical	25184681
BABA1_HUMAN	BABAM1	physical	25184681
CENPB_HUMAN	CENPB	physical	25184681
DDB1_HUMAN	DDB1	physical	25184681
DDX54_HUMAN	DDX54	physical	25184681
DNJA1_HUMAN	DNAJA1	physical	25184681
EBP2_HUMAN	EBNA1BP2	physical	25184681
ABRX1_HUMAN	FAM175A	physical	25184681
FA83A_HUMAN	FAM83A	physical	25184681
GAR1_HUMAN	GAR1	physical	25184681
GNL3L_HUMAN	GNL3L	physical	25184681
HERC1_HUMAN	HERC1	physical	25184681
IMA1_HUMAN	KPNA2	physical	25184681
MLH1_HUMAN	MLH1	physical	25184681
MSH6_HUMAN	MSH6	physical	25184681
NAT10_HUMAN	NAT10	physical	25184681
NOP2_HUMAN	NOP2	physical	25184681
NUMA1_HUMAN	NUMA1	physical	25184681
PGAM5_HUMAN	PGAM5	physical	25184681
PMS2_HUMAN	PMS2	physical	25184681
CTIP_HUMAN	RBBP8	physical	25184681
RBM28_HUMAN	RBM28	physical	25184681
RCL1_HUMAN	RCL1	physical	25184681
RL21_HUMAN	RPL21	physical	25184681
RL28_HUMAN	RPL28	physical	25184681
RL3_HUMAN	RPL3	physical	25184681
RL32_HUMAN	RPL32	physical	25184681
RL34_HUMAN	RPL34	physical	25184681
RS27_HUMAN	RPS27	physical	25184681
RS7_HUMAN	RPS7	physical	25184681
RL1D1_HUMAN	RSL1D1	physical	25184681
RUVB2_HUMAN	RUVBL2	physical	25184681
SETX_HUMAN	SETX	physical	25184681
UIMC1_HUMAN	UIMC1	physical	25184681
ZCCHV_HUMAN	ZC3HAV1	physical	25184681
ABCF2_HUMAN	ABCF2	physical	25184681
AFAP1_HUMAN	AFAP1	physical	25184681
BRCA2_HUMAN	BRCA2	physical	25184681
CBX3_HUMAN	CBX3	physical	25184681
CDC16_HUMAN	CDC16	physical	25184681
CDCA2_HUMAN	CDCA2	physical	25184681
CEBPB_HUMAN	CEBPB	physical	25184681
UTP4_HUMAN	CIRH1A	physical	25184681
NEUA_HUMAN	CMAS	physical	25184681
CREB5_HUMAN	CREB5	physical	25184681
KC1D_HUMAN	CSNK1D	physical	25184681
DDX23_HUMAN	DDX23	physical	25184681
DX39A_HUMAN	DDX39A	physical	25184681
DNMT1_HUMAN	DNMT1	physical	25184681
FHL2_HUMAN	FHL2	physical	25184681
FWCH1_HUMAN	FLYWCH1	physical	25184681
FOSL2_HUMAN	FOSL2	physical	25184681
P66B_HUMAN	GATAD2B	physical	25184681
GT2D1_HUMAN	GTF2IRD1	physical	25184681
HMMR_HUMAN	HMMR	physical	25184681
JUNB_HUMAN	JUNB	physical	25184681
KI20A_HUMAN	KIF20A	physical	25184681
KIF22_HUMAN	KIF22	physical	25184681
KI67_HUMAN	MKI67	physical	25184681
MO4L2_HUMAN	MORF4L2	physical	25184681
MRE11_HUMAN	MRE11A	physical	25184681
MTA2_HUMAN	MTA2	physical	25184681
NBN_HUMAN	NBN	physical	25184681
NIPBL_HUMAN	NIPBL	physical	25184681
NOL11_HUMAN	NOL11	physical	25184681
SOSB1_HUMAN	NABP2	physical	25184681
ORC2_HUMAN	ORC2	physical	25184681
PALB2_HUMAN	PALB2	physical	25184681
PCNA_HUMAN	PCNA	physical	25184681
RPB1_HUMAN	POLR2A	physical	25184681
RAD18_HUMAN	RAD18	physical	25184681
RAD21_HUMAN	RAD21	physical	25184681
RAD50_HUMAN	RAD50	physical	25184681
RFC1_HUMAN	RFC1	physical	25184681
RFC2_HUMAN	RFC2	physical	25184681
RFC4_HUMAN	RFC4	physical	25184681
RN169_HUMAN	RNF169	physical	25184681
RS13_HUMAN	RPS13	physical	25184681
SLAI2_HUMAN	SLAIN2	physical	25184681
SMCA5_HUMAN	SMARCA5	physical	25184681
SMC1A_HUMAN	SMC1A	physical	25184681
SMC3_HUMAN	SMC3	physical	25184681
TERF2_HUMAN	TERF2	physical	25184681
TONSL_HUMAN	TONSL	physical	25184681
TOP2A_HUMAN	TOP2A	physical	25184681
TOPB1_HUMAN	TOPBP1	physical	25184681
TPX2_HUMAN	TPX2	physical	25184681
UBP7_HUMAN	USP7	physical	25184681
WAPL_HUMAN	WAPAL	physical	25184681
WIZ_HUMAN	WIZ	physical	25184681
ZC11A_HUMAN	ZC3H11A	physical	25184681
ZZZ3_HUMAN	ZZZ3	physical	25184681
SETX_HUMAN	SETX	genetic	25184681
TEANC_HUMAN	TCEANC	genetic	25184681
TCEA2_HUMAN	TCEA2	genetic	25184681
TONSL_HUMAN	TONSL	genetic	25184681
SSRP1_HUMAN	SSRP1	genetic	25184681
SP16H_HUMAN	SUPT16H	genetic	25184681
SSRP1_HUMAN	SSRP1	physical	25184681
SP16H_HUMAN	SUPT16H	physical	25184681
H2AX_HUMAN	H2AFX	physical	11927591
UBE2K_HUMAN	UBE2K	physical	21965653
UB2D1_HUMAN	UBE2D1	physical	19916563
BLM_HUMAN	BLM	physical	25084169
LEG3_HUMAN	LGALS3	physical	24755837
RPAB3_HUMAN	POLR2H	physical	25436519
UBE2W_HUMAN	UBE2W	physical	25436519
ACACA_HUMAN	ACACA	physical	24565757
SETX_HUMAN	SETX	physical	25699710
NCOA1_HUMAN	NCOA1	physical	16860316
CCNA2_HUMAN	CCNA2	physical	9244350
BARD1_HUMAN	BARD1	physical	25823446
HERC2_HUMAN	HERC2	physical	25480944
EZH2_HUMAN	EZH2	physical	25531315
RAD51_HUMAN	RAD51	physical	25499220
PARP1_HUMAN	PARP1	physical	25252691
BACH1_HUMAN	BACH1	physical	25252691
CTIP_HUMAN	RBBP8	physical	25252691
BRCC3_HUMAN	BRCC3	physical	25252691
UIMC1_HUMAN	UIMC1	physical	25252691
PSA7_HUMAN	PSMA7	physical	25620702
CBX3_HUMAN	CBX3	physical	25634209
CBX5_HUMAN	CBX5	physical	25634209
CBX1_HUMAN	CBX1	physical	25634209
NBN_HUMAN	NBN	physical	25939603
PALB2_HUMAN	PALB2	physical	26649820
IF16_HUMAN	IFI16	physical	26121674
H2AX_HUMAN	H2AFX	physical	26121674
CHK2_HUMAN	CHEK2	physical	26121674
CASP1_HUMAN	CASP1	physical	26121674
ASC_HUMAN	PYCARD	physical	26121674
PALB2_HUMAN	PALB2	physical	25652403
BARD1_HUMAN	BARD1	physical	25652403
FACD2_HUMAN	FANCD2	physical	25652403
BRCA2_HUMAN	BRCA2	physical	25652403
CCNB1_HUMAN	CCNB1	physical	23246971
MPIP3_HUMAN	CDC25C	physical	23246971
UB2D3_HUMAN	UBE2D3	physical	23246971
UBE2K_HUMAN	UBE2K	physical	23246971
CTIP_HUMAN	RBBP8	physical	25659039
NBN_HUMAN	NBN	physical	25659039
RAD51_HUMAN	RAD51	physical	25659039
ANR28_HUMAN	ANKRD28	physical	27026398
BARD1_HUMAN	BARD1	physical	26490435
UIMC1_HUMAN	UIMC1	physical	26446986
CTIP_HUMAN	RBBP8	physical	26446986
ERCC5_HUMAN	ERCC5	physical	26833090
WEE1_HUMAN	WEE1	genetic	28319113
CADH1_HUMAN	CDH1	genetic	28319113
BRD4_HUMAN	BRD4	genetic	28319113
PGFRA_HUMAN	PDGFRA	genetic	28319113
VEGFA_HUMAN	VEGFA	genetic	28319113
PARP1_HUMAN	PARP1	genetic	28319113
FLT3_HUMAN	FLT3	genetic	28319113
FNTA_HUMAN	FNTA	genetic	28319113
RUNX1_HUMAN	RUNX1	genetic	28319113
CHK1_HUMAN	CHEK1	genetic	28319113
TOP1_HUMAN	TOP1	genetic	28319113
RB_HUMAN	RB1	genetic	28319113
HDAC2_HUMAN	HDAC2	genetic	28319113
RPB1_HUMAN	POLR2A	physical	27583302
RPA1_HUMAN	POLR1A	physical	27589844
UBF1_HUMAN	UBTF	physical	27589844
TAF1B_HUMAN	TAF1B	physical	27589844
BARD1_HUMAN	BARD1	physical	28514442
MSH2_HUMAN	MSH2	genetic	24966277
FANCJ_HUMAN	BRIP1	physical	23157317
DPOLN_HUMAN	POLN	physical	26269593
BARD1_HUMAN	BARD1	physical	28948225
BARD1_HUMAN	BARD1	physical	26831064
PP6R3_HUMAN	PPP6R3	physical	26831064
PPP6_HUMAN	PPP6C	physical	26831064
AURKA_HUMAN	AURKA	physical	26831064
NDKA_HUMAN	NME1	physical	26831064
GRN_HUMAN	GRN	physical	26831064
FLNA_HUMAN	FLNA	physical	26831064
LG3BP_HUMAN	LGALS3BP	physical	26831064
CEP72_HUMAN	CEP72	physical	26831064
HCFC1_HUMAN	HCFC1	physical	26831064
TPIS_HUMAN	TPI1	physical	26831064
ZFR_HUMAN	ZFR	physical	26831064
IF2B3_HUMAN	IGF2BP3	physical	26831064
S39A6_HUMAN	SLC39A6	physical	26831064
ATX2L_HUMAN	ATXN2L	physical	26831064
UBAP2_HUMAN	UBAP2	physical	26831064
SMRC1_HUMAN	SMARCC1	physical	26831064
NU214_HUMAN	NUP214	physical	26831064
HNRPL_HUMAN	HNRNPL	physical	26831064
SF3B2_HUMAN	SF3B2	physical	26831064
PUR2_HUMAN	GART	physical	26831064
NU160_HUMAN	NUP160	physical	26831064
SF3B3_HUMAN	SF3B3	physical	26831064
SC16A_HUMAN	SEC16A	physical	26831064
HNRL1_HUMAN	HNRNPUL1	physical	26831064
RBM6_HUMAN	RBM6	physical	26831064
RL28_HUMAN	RPL28	physical	26831064
RLA1_HUMAN	RPLP1	physical	26831064
F120A_HUMAN	FAM120A	physical	26831064
NDC1_HUMAN	NDC1	physical	26831064
CAPR1_HUMAN	CAPRIN1	physical	26831064
HNRDL_HUMAN	HNRNPDL	physical	26831064
RBM14_HUMAN	RBM14	physical	26831064
FUS_HUMAN	FUS	physical	26831064
SF3B1_HUMAN	SF3B1	physical	26831064
MATR3_HUMAN	MATR3	physical	26831064
ILF2_HUMAN	ILF2	physical	26831064
SC23A_HUMAN	SEC23A	physical	26831064
LMNA_HUMAN	LMNA	physical	26831064
PABP1_HUMAN	PABPC1	physical	26831064
SC24C_HUMAN	SEC24C	physical	26831064
RBP56_HUMAN	TAF15	physical	26831064
RS16_HUMAN	RPS16	physical	26831064
MBB1A_HUMAN	MYBBP1A	physical	26831064
TBA4A_HUMAN	TUBA4A	physical	26831064
RS27_HUMAN	RPS27	physical	26831064
ASH2L_HUMAN	ASH2L	physical	26831064
SEPT9_HUMAN	SEPT9	physical	26831064
PCMD2_HUMAN	PCMTD2	physical	26831064
ROAA_HUMAN	HNRNPAB	physical	26831064
SC23B_HUMAN	SEC23B	physical	26831064
BPTF_HUMAN	BPTF	physical	26831064
DDX21_HUMAN	DDX21	physical	26831064
U5S1_HUMAN	EFTUD2	physical	26831064
EWS_HUMAN	EWSR1	physical	26831064
SYQ_HUMAN	QARS	physical	26831064
HNRPR_HUMAN	HNRNPR	physical	26831064
RS25_HUMAN	RPS25	physical	26831064
SMCA4_HUMAN	SMARCA4	physical	26831064
RL12_HUMAN	RPL12	physical	26831064
RS13_HUMAN	RPS13	physical	26831064
LARP1_HUMAN	LARP1	physical	26831064
PRP6_HUMAN	PRPF6	physical	26831064
RS7_HUMAN	RPS7	physical	26831064
YBOX1_HUMAN	YBX1	physical	26831064
SC24B_HUMAN	SEC24B	physical	26831064
ANM1_HUMAN	PRMT1	physical	26831064
GRPE1_HUMAN	GRPEL1	physical	26831064
RS2_HUMAN	RPS2	physical	26831064
CDC5L_HUMAN	CDC5L	physical	26831064
PLEC_HUMAN	PLEC	physical	26831064
RS5_HUMAN	RPS5	physical	26831064
AGO2_HUMAN	AGO2	physical	26831064
EZRI_HUMAN	EZR	physical	26831064
AKAP8_HUMAN	AKAP8	physical	26831064
DHX15_HUMAN	DHX15	physical	26831064
SYIC_HUMAN	IARS	physical	26831064
HNRPM_HUMAN	HNRNPM	physical	26831064
XRCC5_HUMAN	XRCC5	physical	26831064
CUL2_HUMAN	CUL2	physical	26831064
DHX9_HUMAN	DHX9	physical	26831064
RS3_HUMAN	RPS3	physical	26831064
TROAP_HUMAN	TROAP	physical	26831064
PRS6A_HUMAN	PSMC3	physical	26831064
GANAB_HUMAN	GANAB	physical	26831064
HNRPD_HUMAN	HNRNPD	physical	26831064
ENPL_HUMAN	HSP90B1	physical	26831064
ROA2_HUMAN	HNRNPA2B1	physical	26831064
SPTN1_HUMAN	SPTAN1	physical	26831064
RBBP5_HUMAN	RBBP5	physical	26831064
RL8_HUMAN	RPL8	physical	26831064
HNRH1_HUMAN	HNRNPH1	physical	26831064
RS11_HUMAN	RPS11	physical	26831064
HSPB1_HUMAN	HSPB1	physical	26831064
SFPQ_HUMAN	SFPQ	physical	26831064
DDX5_HUMAN	DDX5	physical	26831064
TIAR_HUMAN	TIAL1	physical	26831064
MVP_HUMAN	MVP	physical	26831064
G3P_HUMAN	GAPDH	physical	26831064
SMCA5_HUMAN	SMARCA5	physical	26831064
HNRH3_HUMAN	HNRNPH3	physical	26831064
AAAS_HUMAN	AAAS	physical	26831064
HNRH2_HUMAN	HNRNPH2	physical	26831064
K1C18_HUMAN	KRT18	physical	26831064
SAHH_HUMAN	AHCY	physical	26831064
PIMT_HUMAN	PCMT1	physical	26831064
SYLC_HUMAN	LARS	physical	26831064
RUVB2_HUMAN	RUVBL2	physical	26831064
PDIA4_HUMAN	PDIA4	physical	26831064
FLNB_HUMAN	FLNB	physical	26831064
RL18A_HUMAN	RPL18A	physical	26831064
SPTB2_HUMAN	SPTBN1	physical	26831064
SYEP_HUMAN	EPRS	physical	26831064
RL18_HUMAN	RPL18	physical	26831064
SP16H_HUMAN	SUPT16H	physical	26831064
RL27_HUMAN	RPL27	physical	26831064
RS8_HUMAN	RPS8	physical	26831064
BIG1_HUMAN	ARFGEF1	physical	26831064
KHDR1_HUMAN	KHDRBS1	physical	26831064
RL27A_HUMAN	RPL27A	physical	26831064
SYDC_HUMAN	DARS	physical	26831064
XRCC6_HUMAN	XRCC6	physical	26831064
RS14_HUMAN	RPS14	physical	26831064
SF3A3_HUMAN	SF3A3	physical	26831064
LRRF1_HUMAN	LRRFIP1	physical	26831064
RL3_HUMAN	RPL3	physical	26831064
SSFA2_HUMAN	SSFA2	physical	26831064
ILF3_HUMAN	ILF3	physical	26831064
SYRC_HUMAN	RARS	physical	26831064
ROA3_HUMAN	HNRNPA3	physical	26831064
RL4_HUMAN	RPL4	physical	26831064
RL23_HUMAN	RPL23	physical	26831064
TFG_HUMAN	TFG	physical	26831064
UGGG1_HUMAN	UGGT1	physical	26831064
HNRL2_HUMAN	HNRNPUL2	physical	26831064
HYOU1_HUMAN	HYOU1	physical	26831064
SMC3_HUMAN	SMC3	physical	26831064
HNRPQ_HUMAN	SYNCRIP	physical	26831064
EF1G_HUMAN	EEF1G	physical	26831064
UBP2L_HUMAN	UBAP2L	physical	26831064
S39AA_HUMAN	SLC39A10	physical	26831064
STIP1_HUMAN	STIP1	physical	26831064
TCPE_HUMAN	CCT5	physical	26831064
IPO7_HUMAN	IPO7	physical	26831064
DNJA1_HUMAN	DNAJA1	physical	26831064
LRRK1_HUMAN	LRRK1	physical	26831064
RSSA_HUMAN	RPSA	physical	26831064
MAP4_HUMAN	MAP4	physical	26831064
RL17_HUMAN	RPL17	physical	26831064
ARI1_HUMAN	ARIH1	physical	26831064
HNRPK_HUMAN	HNRNPK	physical	26831064
RS19_HUMAN	RPS19	physical	26831064
TP53B_HUMAN	TP53BP1	physical	26831064
SMC1A_HUMAN	SMC1A	physical	26831064
UBA1_HUMAN	UBA1	physical	26831064
1433E_HUMAN	YWHAE	physical	26831064
RL7_HUMAN	RPL7	physical	26831064
PROF1_HUMAN	PFN1	physical	26831064
FANCJ_HUMAN	BRIP1	physical	26831064
GRP75_HUMAN	HSPA9	physical	26831064
MYH9_HUMAN	MYH9	physical	26831064
XPO1_HUMAN	XPO1	physical	26831064
RL10A_HUMAN	RPL10A	physical	26831064
RS15A_HUMAN	RPS15A	physical	26831064
RL31_HUMAN	RPL31	physical	26831064
PSA_HUMAN	NPEPPS	physical	26831064
ALMS1_HUMAN	ALMS1	physical	26831064
CKAP5_HUMAN	CKAP5	physical	26831064
BLM_HUMAN	BLM	physical	26831064
RL30_HUMAN	RPL30	physical	26831064
RL11_HUMAN	RPL11	physical	26831064
ALDOA_HUMAN	ALDOA	physical	26831064
TCPB_HUMAN	CCT2	physical	26831064
RLA2_HUMAN	RPLP2	physical	26831064
IF4G1_HUMAN	EIF4G1	physical	26831064
TPP2_HUMAN	TPP2	physical	26831064
RS24_HUMAN	RPS24	physical	26831064
ZN363_HUMAN	RCHY1	physical	26831064
SF3A1_HUMAN	SF3A1	physical	26831064
RS12_HUMAN	RPS12	physical	26831064
ENOA_HUMAN	ENO1	physical	26831064
RS23_HUMAN	RPS23	physical	26831064
ROA0_HUMAN	HNRNPA0	physical	26831064
ACLY_HUMAN	ACLY	physical	26831064
RUVB1_HUMAN	RUVBL1	physical	26831064
PSA5_HUMAN	PSMA5	physical	26831064
RS3A_HUMAN	RPS3A	physical	26831064
TCPH_HUMAN	CCT7	physical	26831064
TCPD_HUMAN	CCT4	physical	26831064
RL23A_HUMAN	RPL23A	physical	26831064
LDHB_HUMAN	LDHB	physical	26831064
PYRG1_HUMAN	CTPS1	physical	26831064
CLH1_HUMAN	CLTC	physical	26831064
AIMP2_HUMAN	AIMP2	physical	26831064
HNRPF_HUMAN	HNRNPF	physical	26831064
IQGA1_HUMAN	IQGAP1	physical	26831064
GLU2B_HUMAN	PRKCSH	physical	26831064
HNRPU_HUMAN	HNRNPU	physical	26831064
NUCL_HUMAN	NCL	physical	26831064
MYH14_HUMAN	MYH14	physical	26831064
GRP78_HUMAN	HSPA5	physical	26831064
NAT10_HUMAN	NAT10	physical	26831064
HSP74_HUMAN	HSPA4	physical	26831064
LDHA_HUMAN	LDHA	physical	26831064
NPM_HUMAN	NPM1	physical	26831064
CCAR2_HUMAN	CCAR2	physical	26831064
PRS6B_HUMAN	PSMC4	physical	26831064
RL34_HUMAN	RPL34	physical	26831064
RL5_HUMAN	RPL5	physical	26831064
TCPZ_HUMAN	CCT6A	physical	26831064
KPYM_HUMAN	PKM	physical	26831064
IMB1_HUMAN	KPNB1	physical	26831064
IPO5_HUMAN	IPO5	physical	26831064
PARP1_HUMAN	PARP1	physical	26831064
RL37A_HUMAN	RPL37A	physical	26831064
MYH10_HUMAN	MYH10	physical	26831064
TCPG_HUMAN	CCT3	physical	26831064
PSD13_HUMAN	PSMD13	physical	26831064
MCM3_HUMAN	MCM3	physical	26831064
RS18_HUMAN	RPS18	physical	26831064
U520_HUMAN	SNRNP200	physical	26831064
TBB8_HUMAN	TUBB8	physical	26831064
KDM1A_HUMAN	KDM1A	physical	26831064
RAGP1_HUMAN	RANGAP1	physical	26831064
TBA1C_HUMAN	TUBA1C	physical	26831064
FAS_HUMAN	FASN	physical	26831064
TBB4B_HUMAN	TUBB4B	physical	26831064
RL21_HUMAN	RPL21	physical	26831064
GOGA5_HUMAN	GOLGA5	physical	26831064
PSD11_HUMAN	PSMD11	physical	26831064
CAP1_HUMAN	CAP1	physical	26831064
TCPQ_HUMAN	CCT8	physical	26831064
TBB5_HUMAN	TUBB	physical	26831064
RALY_HUMAN	RALY	physical	26831064
DNJA2_HUMAN	DNAJA2	physical	26831064
PRDX1_HUMAN	PRDX1	physical	26831064
NACAM_HUMAN	NACA	physical	26831064
NACA_HUMAN	NACA	physical	26831064
DYR1A_HUMAN	DYRK1A	physical	26831064
TLN1_HUMAN	TLN1	physical	26831064
EF1B_HUMAN	EEF1B2	physical	26831064
DESP_HUMAN	DSP	physical	26831064
SEPT7_HUMAN	SEPT7	physical	26831064
RS6_HUMAN	RPS6	physical	26831064
TCPA_HUMAN	TCP1	physical	26831064
RL7A_HUMAN	RPL7A	physical	26831064
CRBN_HUMAN	CRBN	physical	26831064
RL15_HUMAN	RPL15	physical	26831064
KI67_HUMAN	MKI67	physical	26831064
MCM4_HUMAN	MCM4	physical	26831064
KIF23_HUMAN	KIF23	physical	26831064
EIF3I_HUMAN	EIF3I	physical	26831064
LA_HUMAN	SSB	physical	26831064
PSA7_HUMAN	PSMA7	physical	26831064
1433T_HUMAN	YWHAQ	physical	26831064
NUMA1_HUMAN	NUMA1	physical	26831064
RAN_HUMAN	RAN	physical	26831064
PSMD1_HUMAN	PSMD1	physical	26831064
PUR6_HUMAN	PAICS	physical	26831064
PDIA1_HUMAN	P4HB	physical	26831064
EF2_HUMAN	EEF2	physical	26831064
1433Z_HUMAN	YWHAZ	physical	26831064
CHD9_HUMAN	CHD9	physical	26831064
WDR5_HUMAN	WDR5	physical	26831064
SYK_HUMAN	KARS	physical	26831064
HSP7C_HUMAN	HSPA8	physical	26831064
BIG2_HUMAN	ARFGEF2	physical	26831064
NUDC_HUMAN	NUDC	physical	26831064
HS90B_HUMAN	HSP90AB1	physical	26831064
RL35_HUMAN	RPL35	physical	26831064
PSB5_HUMAN	PSMB5	physical	26831064
VINC_HUMAN	VCL	physical	26831064
HS105_HUMAN	HSPH1	physical	26831064
RPTOR_HUMAN	RPTOR	physical	26831064
COPB2_HUMAN	COPB2	physical	26831064
PRP39_HUMAN	PRPF39	physical	26831064
PYR1_HUMAN	CAD	physical	26831064
LRC59_HUMAN	LRRC59	physical	26831064
YTHD3_HUMAN	YTHDF3	physical	26831064
EIF3G_HUMAN	EIF3G	physical	26831064
IMA1_HUMAN	KPNA2	physical	26831064
EIF3E_HUMAN	EIF3E	physical	26831064
PSMD3_HUMAN	PSMD3	physical	26831064
SYMC_HUMAN	MARS	physical	26831064
SYVC_HUMAN	VARS	physical	26831064
KINH_HUMAN	KIF5B	physical	26831064
PARP4_HUMAN	PARP4	physical	26831064
EIF3A_HUMAN	EIF3A	physical	26831064
M3K21_HUMAN	KIAA1804	physical	26831064
RL24_HUMAN	RPL24	physical	26831064
RL9_HUMAN	RPL9	physical	26831064
MCM6_HUMAN	MCM6	physical	26831064
XPO2_HUMAN	CSE1L	physical	26831064
TBB6_HUMAN	TUBB6	physical	26831064
TERA_HUMAN	VCP	physical	26831064
FLII_HUMAN	FLII	physical	26831064
COPA_HUMAN	COPA	physical	26831064
HS90A_HUMAN	HSP90AA1	physical	26831064
TPR_HUMAN	TPR	physical	26831064
PRS7_HUMAN	PSMC2	physical	26831064
AHNK_HUMAN	AHNAK	physical	26831064
KI20B_HUMAN	KIF20B	physical	26831064
TNR6A_HUMAN	TNRC6A	physical	26831064
DJC10_HUMAN	DNAJC10	physical	26831064
PSD12_HUMAN	PSMD12	physical	26831064
AP2B1_HUMAN	AP2B1	physical	26831064
PDC6I_HUMAN	PDCD6IP	physical	26831064
GDE_HUMAN	AGL	physical	26831064
EIF3B_HUMAN	EIF3B	physical	26831064
G6PI_HUMAN	GPI	physical	26831064
DDB1_HUMAN	DDB1	physical	26831064
NOP2_HUMAN	NOP2	physical	26831064
PSMD2_HUMAN	PSMD2	physical	26831064
GCN1_HUMAN	GCN1L1	physical	26831064
TIF1B_HUMAN	TRIM28	physical	26831064
CARM1_HUMAN	CARM1	physical	26831064
EF1D_HUMAN	EEF1D	physical	26831064
COPB_HUMAN	COPB1	physical	26831064
AKA12_HUMAN	AKAP12	physical	26831064
PALLD_HUMAN	PALLD	physical	26831064
TNR6C_HUMAN	TNRC6C	physical	26831064
RS9_HUMAN	RPS9	physical	26831064
TNR6B_HUMAN	TNRC6B	physical	26831064
CENPF_HUMAN	CENPF	physical	26831064
EBP2_HUMAN	EBNA1BP2	physical	26831064
PSMD7_HUMAN	PSMD7	physical	26831064
CTNA1_HUMAN	CTNNA1	physical	26831064
IMA4_HUMAN	KPNA3	physical	26831064
COPG1_HUMAN	COPG1	physical	26831064
NUFP2_HUMAN	NUFIP2	physical	26831064
PYGL_HUMAN	PYGL	physical	26831064
GEMI5_HUMAN	GEMIN5	physical	26831064
PRKRA_HUMAN	PRKRA	physical	26831064
PDLI5_HUMAN	PDLIM5	physical	26831064
IPYR_HUMAN	PPA1	physical	26831064
PABP4_HUMAN	PABPC4	physical	26831064
NU133_HUMAN	NUP133	physical	26831064
UBR1_HUMAN	UBR1	physical	26831064
KT3K_HUMAN	FN3KRP	physical	26831064
NUP93_HUMAN	NUP93	physical	26831064
KIFC1_HUMAN	KIFC1	physical	26831064
TBB3_HUMAN	TUBB3	physical	26831064
CAZA1_HUMAN	CAPZA1	physical	26831064
DDX6_HUMAN	DDX6	physical	26831064
NAA15_HUMAN	NAA15	physical	26831064
RL36_HUMAN	RPL36	physical	26831064
TBL3_HUMAN	TBL3	physical	26831064
S23IP_HUMAN	SEC23IP	physical	26831064
PA2G4_HUMAN	PA2G4	physical	26831064
STAU1_HUMAN	STAU1	physical	26831064
TNPO1_HUMAN	TNPO1	physical	26831064
GIPC1_HUMAN	GIPC1	physical	26831064
KI20A_HUMAN	KIF20A	physical	26831064
SEPT2_HUMAN	SEPT2	physical	26831064
PSDE_HUMAN	PSMD14	physical	26831064
TF3C6_HUMAN	GTF3C6	physical	26831064
KIF11_HUMAN	KIF11	physical	26831064
ZBT47_HUMAN	ZBTB47	physical	26831064
MCM5_HUMAN	MCM5	physical	26831064
GUAA_HUMAN	GMPS	physical	26831064
GARS_HUMAN	GARS	physical	26831064
USO1_HUMAN	USO1	physical	26831064
SART3_HUMAN	SART3	physical	26831064
ECM29_HUMAN	KIAA0368	physical	26831064
HS71L_HUMAN	HSPA1L	physical	26831064
VPS35_HUMAN	VPS35	physical	26831064
SRP68_HUMAN	SRP68	physical	26831064
CAND1_HUMAN	CAND1	physical	26831064
RL14_HUMAN	RPL14	physical	26831064
PRS4_HUMAN	PSMC1	physical	26831064
ANM5_HUMAN	PRMT5	physical	26831064
AGO3_HUMAN	AGO3	physical	26831064
IF2P_HUMAN	EIF5B	physical	26831064
DCAF7_HUMAN	DCAF7	physical	26831064
SERPH_HUMAN	SERPINH1	physical	26831064
ZY11B_HUMAN	ZYG11B	physical	26831064
DC1I2_HUMAN	DYNC1I2	physical	26831064
FBRL_HUMAN	FBL	physical	26831064
HS74L_HUMAN	HSPA4L	physical	26831064
DDX1_HUMAN	DDX1	physical	26831064
SND1_HUMAN	SND1	physical	26831064
PSA1_HUMAN	PSMA1	physical	26831064
NP1L1_HUMAN	NAP1L1	physical	26831064
TALDO_HUMAN	TALDO1	physical	26831064
PSME3_HUMAN	PSME3	physical	26831064
RACK1_HUMAN	GNB2L1	physical	26831064
PRS8_HUMAN	PSMC5	physical	26831064
SYTC_HUMAN	TARS	physical	26831064
SC31A_HUMAN	SEC31A	physical	26831064
RENT1_HUMAN	UPF1	physical	26831064
CNN2_HUMAN	CNN2	physical	26831064
RL6_HUMAN	RPL6	physical	26831064
RL10_HUMAN	RPL10	physical	26831064
SUMO1_HUMAN	SUMO1	physical	26831064
CNOT1_HUMAN	CNOT1	physical	26831064
NOLC1_HUMAN	NOLC1	physical	26831064
TSAP1_HUMAN	TRNAU1AP	physical	26831064
TFR1_HUMAN	TFRC	physical	26831064
EXOSX_HUMAN	EXOSC10	physical	26831064
RB6I2_HUMAN	ERC1	physical	26831064
APEX1_HUMAN	APEX1	physical	26831064
THEGL_HUMAN	THEGL	physical	26831064
NKRF_HUMAN	NKRF	physical	26831064
DNJA4_HUMAN	DNAJA4	physical	26831064
UBP7_HUMAN	USP7	physical	26831064
SMRC2_HUMAN	SMARCC2	physical	26831064
NU155_HUMAN	NUP155	physical	26831064
SMD3_HUMAN	SNRPD3	physical	26831064
PTBP1_HUMAN	PTBP1	physical	26831064
HMMR_HUMAN	HMMR	physical	26831064
PCBP1_HUMAN	PCBP1	physical	26831064
AIMP1_HUMAN	AIMP1	physical	26831064
ZN326_HUMAN	ZNF326	physical	26831064
OGT1_HUMAN	OGT	physical	26831064
SRP72_HUMAN	SRP72	physical	26831064
NU107_HUMAN	NUP107	physical	26831064
FKBP4_HUMAN	FKBP4	physical	26831064
HEM6_HUMAN	CPOX	physical	26831064
DDX17_HUMAN	DDX17	physical	26831064
DCTN1_HUMAN	DCTN1	physical	26831064
TCOF_HUMAN	TCOF1	physical	26831064
RBBP4_HUMAN	RBBP4	physical	26831064
MAGB2_HUMAN	MAGEB2	physical	26831064
PDS5A_HUMAN	PDS5A	physical	26831064
NOL11_HUMAN	NOL11	physical	26831064
STRAP_HUMAN	STRAP	physical	26831064
ANXA1_HUMAN	ANXA1	physical	26831064
PFKAP_HUMAN	PFKP	physical	26831064
KCC2D_HUMAN	CAMK2D	physical	26831064
TITIN_HUMAN	TTN	physical	26831064
TKT_HUMAN	TKT	physical	26831064
PFKAM_HUMAN	PFKM	physical	26831064
CDC37_HUMAN	CDC37	physical	26831064
NOP56_HUMAN	NOP56	physical	26831064
DPY30_HUMAN	DPY30	physical	26831064
UBIM_HUMAN	FAU	physical	26831064
DIM1_HUMAN	DIMT1	physical	26831064
KLH22_HUMAN	KLHL22	physical	26831064
EIF3H_HUMAN	EIF3H	physical	26831064
CTNB1_HUMAN	CTNNB1	physical	26831064
ANXA5_HUMAN	ANXA5	physical	26831064
SERA_HUMAN	PHGDH	physical	26831064
GP161_HUMAN	GPR161	physical	26831064
EIF3M_HUMAN	EIF3M	physical	26831064
MCES_HUMAN	RNMT	physical	26831064
ACPH_HUMAN	APEH	physical	26831064
HP1B3_HUMAN	HP1BP3	physical	26831064
FA98A_HUMAN	FAM98A	physical	26831064
EIF3L_HUMAN	EIF3L	physical	26831064
JIP4_HUMAN	SPAG9	physical	26831064
UCHL5_HUMAN	UCHL5	physical	26831064
OGFR_HUMAN	OGFR	physical	26831064
XRN2_HUMAN	XRN2	physical	26831064
PRP19_HUMAN	PRPF19	physical	26831064
SNX9_HUMAN	SNX9	physical	26831064
PSMD4_HUMAN	PSMD4	physical	26831064
PDE12_HUMAN	PDE12	physical	26831064
IF2A_HUMAN	EIF2S1	physical	26831064
BUB3_HUMAN	BUB3	physical	26831064
MDHM_HUMAN	MDH2	physical	26831064
6PGD_HUMAN	PGD	physical	26831064
CFA47_HUMAN	CXorf22	physical	26831064
EXOS8_HUMAN	EXOSC8	physical	26831064
DIAP1_HUMAN	DIAPH1	physical	26831064
PSMD6_HUMAN	PSMD6	physical	26831064
FUBP2_HUMAN	KHSRP	physical	26831064
C1TC_HUMAN	MTHFD1	physical	26831064
PFKAL_HUMAN	PFKL	physical	26831064
CSDE1_HUMAN	CSDE1	physical	26831064
CLIC1_HUMAN	CLIC1	physical	26831064
MOV10_HUMAN	MOV10	physical	26831064
SET1A_HUMAN	SETD1A	physical	26831064
NSF_HUMAN	NSF	physical	26831064
MCM2_HUMAN	MCM2	physical	26831064
MDHC_HUMAN	MDH1	physical	26831064
ADRM1_HUMAN	ADRM1	physical	26831064
MKRN2_HUMAN	MKRN2	physical	26831064
NU153_HUMAN	NUP153	physical	26831064
SEC13_HUMAN	SEC13	physical	26831064
UBR2_HUMAN	UBR2	physical	26831064
CLIP1_HUMAN	CLIP1	physical	26831064
PRS10_HUMAN	PSMC6	physical	26831064
RL29_HUMAN	RPL29	physical	26831064
TRA2B_HUMAN	TRA2B	physical	26831064
SYAC_HUMAN	AARS	physical	26831064
IMDH2_HUMAN	IMPDH2	physical	26831064
PGK1_HUMAN	PGK1	physical	26831064
TRI25_HUMAN	TRIM25	physical	26831064
PCNA_HUMAN	PCNA	physical	26831064
LMNB1_HUMAN	LMNB1	physical	26831064
FLNC_HUMAN	FLNC	physical	26831064
WWOX_HUMAN	WWOX	physical	27869163
P53_HUMAN	TP53	physical	26140185

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 114480: Breast cancer (BC)
• 604370: Breast-ovarian cancer, familial, 1 (BROVCA1)
• 167000: Ovarian cancer (OC)
• 614320: Pancreatic cancer 4 (PNCA4)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"The CHK2-BRCA1 tumour suppressor pathway ensures chromosomalstability in human somatic cells.";
Stolz A., Ertych N., Kienitz A., Vogel C., Schneider V., Fritz B.,Jacob R., Dittmar G., Weichert W., Petersen I., Bastians H.;
Nat. Cell Biol. 12:492-499(2010).
Cited for: FUNCTION IN CHROMOSOMAL STABILITY, AND PHOSPHORYLATION AT SER-988 BYCHEK2.
PubMed: 20364141

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-395 AND SER-398, ANDMASS SPECTROMETRY.
PubMed: 19690332

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-395; SER-398; SER-403;SER-753; SER-1211; SER-1217 AND SER-1218, AND MASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1542, AND MASSSPECTROMETRY.
PubMed: 18220336

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1239; SER-1245;SER-1330; SER-1336; SER-1342; SER-1457; SER-1466; SER-1524; THR-1700AND THR-1720, AND MASS SPECTROMETRY.
PubMed: 17525332

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1211; SER-1212;SER-1217; SER-1218 AND SER-1336, AND MASS SPECTROMETRY.
PubMed: 17081983

"BRCA1 phosphorylation by Aurora-A in the regulation of G2 to Mtransition.";
Ouchi M., Fujiuchi N., Sasai K., Katayama H., Minamishima Y.A.,Ongusaha P.P., Deng C., Sen S., Lee S.W., Ouchi T.;
J. Biol. Chem. 279:19643-19648(2004).
Cited for: INTERACTION WITH AURKA, FUNCTION, MUTAGENESIS OF SER-308, ANDPHOSPHORYLATION AT SER-308.
PubMed: 14990569

"hCds1-mediated phosphorylation of BRCA1 regulates the DNA damageresponse.";
Lee J.S., Collins K.M., Brown A.L., Lee C.H., Chung J.H.;
Nature 404:201-204(2000).
Cited for: FUNCTION IN DNA DAMAGE RESPONSE, PHOSPHORYLATION AT SER-988 BY CHEK2,AND INTERACTION WITH CHEK2.
PubMed: 10724175

"Functional interactions between BRCA1 and the checkpoint kinase ATRduring genotoxic stress.";
Tibbetts R.S., Cortez D., Brumbaugh K.M., Scully R., Livingston D.,Elledge S.J., Abraham R.T.;
Genes Dev. 14:2989-3002(2000).
Cited for: PHOSPHORYLATION AT SER-1143; SER-1280; SER-1387; THR-1394; SER-1423AND SER-1457, AND MUTAGENESIS OF SER-1143; SER-1239; SER-1280;SER-1298; SER-1330; SER-1387; THR-1394; SER-1423; SER-1457; SER-1466;SER-1524; THR-1720 AND SER-1755.
PubMed: 11114888