TP53B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TP53B_HUMAN
• UniProt AC: Q12888
• Protein Name: TP53-binding protein 1 {ECO:0000305}
• Gene Name: TP53BP1 {ECO:0000312|HGNC:HGNC:11999}
• Organism: Homo sapiens (Human).
• Sequence Length: 1972
• Subcellular Localization: Nucleus . Chromosome . Chromosome, centromere, kinetochore . Localizes to the nucleus in absence of DNA damage (PubMed:28241136). Following DNA damage, recruited to sites of DNA damage, such as double stand breaks (DSBs): recognizes and binds histone
• Protein Description: Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. [PubMed: 12364621]
• Protein Sequence: MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MDPTGSQLDSDFS --CCCCCCCCCCCCC	30.01	12697768
25	Phosphorylation	PCLIIEDSQPESQVL CEEEEECCCCHHHEE	34.54	12697768
29	Phosphorylation	IEDSQPESQVLEDDS EECCCCHHHEECCCC	32.07	12697768
54	Acetylation	LPNLQTHKENPVLDV CCCCCCCCCCCCEEE	63.68	26051181
54	Ubiquitination	LPNLQTHKENPVLDV CCCCCCCCCCCCEEE	63.68	-
63	Phosphorylation	NPVLDVVSNPEQTAG CCCEEECCCHHHCCC	46.66	30266825
68	Phosphorylation	VVSNPEQTAGEERGD ECCCHHHCCCCCCCC	34.66	25850435
68 (in isoform 2)	Phosphorylation	-	34.66	24719451
78	Phosphorylation	EERGDGNSGFNEHLK CCCCCCCCCHHHHHH	50.74	30266825
83 (in isoform 2)	Phosphorylation	-	43.22	27251275
95	Phosphorylation	KVADPVDSSNLDTCG CCCCCCCCCCCCCCC	22.74	29978859
96	Phosphorylation	VADPVDSSNLDTCGS CCCCCCCCCCCCCCC	36.63	29978859
100	Phosphorylation	VDSSNLDTCGSISQV CCCCCCCCCCCHHHH	23.18	29978859
101 (in isoform 2)	Phosphorylation	-	3.93	27251275
103	Phosphorylation	SNLDTCGSISQVIEQ CCCCCCCCHHHHHHC	22.63	63710687
105	Phosphorylation	LDTCGSISQVIEQLP CCCCCCHHHHHHCCC	21.79	17525332
108 (in isoform 2)	Phosphorylation	-	1.85	27251275
117	Phosphorylation	QLPQPNRTSSVLGMS CCCCCCCCCCCCCCC	31.81	23401153
118	Phosphorylation	LPQPNRTSSVLGMSV CCCCCCCCCCCCCCC	18.40	30266825
119	Phosphorylation	PQPNRTSSVLGMSVE CCCCCCCCCCCCCCC	22.28	30266825
124	Phosphorylation	TSSVLGMSVESAPAV CCCCCCCCCCCCCCH	22.42	30266825
124 (in isoform 2)	Phosphorylation	-	22.42	27251275
127	Phosphorylation	VLGMSVESAPAVEEE CCCCCCCCCCCHHHH	37.08	63763299
129 (in isoform 2)	Phosphorylation	-	46.23	27251275
132 (in isoform 2)	Phosphorylation	-	63.65	27251275
135	Methylation	APAVEEEKGEELEQK CCCHHHHHHHHHHHH	74.93	-
166	Phosphorylation	GAEDTASSQLGFGVL CCCHHCCCHHCCEEE	27.28	17553757
176	Phosphorylation	GFGVLELSQSQDVEE CCEEEECCCCCCCCC	20.57	26074081
178	Phosphorylation	GVLELSQSQDVEENT EEEECCCCCCCCCCC	25.60	26074081
185	Phosphorylation	SQDVEENTVPYEVDK CCCCCCCCCCCCCCH	26.57	22468782
188	Phosphorylation	VEENTVPYEVDKEQL CCCCCCCCCCCHHHH	25.01	46155945
197	Phosphorylation	VDKEQLQSVTTNSGY CCHHHHHHCCCCCCC	29.98	21945579
199	Phosphorylation	KEQLQSVTTNSGYTR HHHHHHCCCCCCCCC	26.05	21945579
200	Phosphorylation	EQLQSVTTNSGYTRL HHHHHCCCCCCCCCH	25.82	21945579
202	Phosphorylation	LQSVTTNSGYTRLSD HHHCCCCCCCCCHHH	30.96	21945579
204	Phosphorylation	SVTTNSGYTRLSDVD HCCCCCCCCCHHHCC	6.63	21945579
205	Phosphorylation	VTTNSGYTRLSDVDA CCCCCCCCCHHHCCH	28.76	21945579
208	Phosphorylation	NSGYTRLSDVDANTA CCCCCCHHHCCHHHH	32.09	30266825
213 (in isoform 2)	Phosphorylation	-	26.11	27251275
214	Phosphorylation	LSDVDANTAIKHEEQ HHHCCHHHHCCCHHH	31.32	23401153
217	Sumoylation	VDANTAIKHEEQSNE CCHHHHCCCHHHCCC	42.36	-
217	Acetylation	VDANTAIKHEEQSNE CCHHHHCCCHHHCCC	42.36	25953088
217	Sumoylation	VDANTAIKHEEQSNE CCHHHHCCCHHHCCC	42.36	25114211
222	Phosphorylation	AIKHEEQSNEDIPIA HCCCHHHCCCCCCHH	45.53	29255136
227 (in isoform 2)	Phosphorylation	-	31.87	24719451
232	Phosphorylation	DIPIAEQSSKDIPVT CCCHHHHHCCCCCCC	30.75	23927012
233	Phosphorylation	IPIAEQSSKDIPVTA CCHHHHHCCCCCCCC	33.76	25159151
234	Ubiquitination	PIAEQSSKDIPVTAQ CHHHHHCCCCCCCCC	65.99	-
239	Phosphorylation	SSKDIPVTAQPSKDV HCCCCCCCCCCCCCE	17.77	30266825
243	Phosphorylation	IPVTAQPSKDVHVVK CCCCCCCCCCEEEEE	29.43	30266825
244	Acetylation	PVTAQPSKDVHVVKE CCCCCCCCCEEEEEC	71.14	23236377
244	Ubiquitination	PVTAQPSKDVHVVKE CCCCCCCCCEEEEEC	71.14	-
250	Acetylation	SKDVHVVKEQNPPPA CCCEEEEECCCCCCC	53.12	26051181
259	Phosphorylation	QNPPPARSEDMPFSP CCCCCCCCCCCCCCC	39.80	23927012
264 (in isoform 2)	Phosphorylation	-	18.33	27251275
265	Phosphorylation	RSEDMPFSPKASVAA CCCCCCCCCHHHHHH	21.44	19664994
269	Phosphorylation	MPFSPKASVAAMEAK CCCCCHHHHHHHHHH	20.58	26074081
270 (in isoform 2)	Phosphorylation	-	4.74	24719451
273	Sulfoxidation	PKASVAAMEAKEQLS CHHHHHHHHHHHHHC	3.57	30846556
280	Phosphorylation	MEAKEQLSAQELMES HHHHHHHCHHHHHHH	27.83	30278072
285 (in isoform 2)	Phosphorylation	-	3.66	27251275
287	Phosphorylation	SAQELMESGLQIQKS CHHHHHHHCCCCCCC	30.73	30278072
292 (in isoform 2)	Phosphorylation	-	27.49	27251275
294	Phosphorylation	SGLQIQKSPEPEVLS HCCCCCCCCCCCCCC	20.37	19664994
299 (in isoform 2)	Phosphorylation	-	8.18	24719451
301	Phosphorylation	SPEPEVLSTQEDLFD CCCCCCCCCHHHHHH	32.97	30266825
302	Phosphorylation	PEPEVLSTQEDLFDQ CCCCCCCCHHHHHHC	31.64	17525332
306 (in isoform 2)	Phosphorylation	-	5.12	27251275
307 (in isoform 2)	Phosphorylation	-	14.37	24719451
310	Phosphorylation	QEDLFDQSNKTVSSD HHHHHHCCCCEECCC	41.98	20068231
313	Phosphorylation	LFDQSNKTVSSDGCS HHHCCCCEECCCCCC	29.85	30266825
315	Phosphorylation	DQSNKTVSSDGCSTP HCCCCEECCCCCCCC	28.13	30266825
316	Phosphorylation	QSNKTVSSDGCSTPS CCCCEECCCCCCCCC	33.41	23401153
320	Phosphorylation	TVSSDGCSTPSREEG EECCCCCCCCCCCCC	49.21	23401153
320 (in isoform 2)	Phosphorylation	-	49.21	27251275
321	Phosphorylation	VSSDGCSTPSREEGG ECCCCCCCCCCCCCC	29.38	30266825
321 (in isoform 2)	Phosphorylation	-	29.38	24719451
323	Phosphorylation	SDGCSTPSREEGGCS CCCCCCCCCCCCCCC	53.03	30266825
326 (in isoform 2)	Phosphorylation	-	60.83	27251275
328 (in isoform 2)	Phosphorylation	-	10.91	27251275
330	Phosphorylation	SREEGGCSLASTPAT CCCCCCCCCCCCCHH	30.19	30266825
333	Phosphorylation	EGGCSLASTPATTLH CCCCCCCCCCHHHHH	39.97	23927012
334	O-linked_Glycosylation	GGCSLASTPATTLHL CCCCCCCCCHHHHHH	16.01	OGP
334	Phosphorylation	GGCSLASTPATTLHL CCCCCCCCCHHHHHH	16.01	23927012
337	Phosphorylation	SLASTPATTLHLLQL CCCCCCHHHHHHHHH	30.97	23927012
338	Phosphorylation	LASTPATTLHLLQLS CCCCCHHHHHHHHHH	17.81	23927012
339 (in isoform 2)	Phosphorylation	-	2.02	27251275
345	Phosphorylation	TLHLLQLSGQRSLVQ HHHHHHHHCCHHHHC	21.66	23927012
349	Phosphorylation	LQLSGQRSLVQDSLS HHHHCCHHHHCCCCC	25.63	22115753
354	Phosphorylation	QRSLVQDSLSTNSSD CHHHHCCCCCCCCCC	13.71	29255136
354 (in isoform 2)	Phosphorylation	-	13.71	27251275
356	Phosphorylation	SLVQDSLSTNSSDLV HHHCCCCCCCCCCCC	29.51	29255136
357	Phosphorylation	LVQDSLSTNSSDLVA HHCCCCCCCCCCCCC	44.40	29255136
359	Phosphorylation	QDSLSTNSSDLVAPS CCCCCCCCCCCCCCC	25.89	29255136
360	Phosphorylation	DSLSTNSSDLVAPSP CCCCCCCCCCCCCCC	36.71	29255136
362 (in isoform 2)	Phosphorylation	-	3.70	24719451
365 (in isoform 2)	Phosphorylation	-	38.63	24719451
366	Phosphorylation	SSDLVAPSPDAFRST CCCCCCCCCCHHHCC	26.19	29255136
371 (in isoform 2)	Phosphorylation	-	41.14	24719451
372	Phosphorylation	PSPDAFRSTPFIVPS CCCCHHHCCCEECCC	33.70	23927012
373	Phosphorylation	SPDAFRSTPFIVPSS CCCHHHCCCEECCCC	20.26	25159151
379	Phosphorylation	STPFIVPSSPTEQEG CCCEECCCCCCCCCC	37.75	22167270
380	Phosphorylation	TPFIVPSSPTEQEGR CCEECCCCCCCCCCC	29.76	29255136
382	Phosphorylation	FIVPSSPTEQEGRQD EECCCCCCCCCCCCC	52.85	29255136
384 (in isoform 2)	Phosphorylation	-	62.01	24719451
385 (in isoform 2)	Phosphorylation	-	50.54	21406692
387 (in isoform 2)	Phosphorylation	-	40.55	27251275
394	Phosphorylation	RQDKPMDTSVLSEEG CCCCCCCHHHHCCCC	17.93	23401153
395	Phosphorylation	QDKPMDTSVLSEEGG CCCCCCHHHHCCCCC	19.45	23927012
398	Phosphorylation	PMDTSVLSEEGGEPF CCCHHHHCCCCCCCH	31.29	29255136
400 (in isoform 2)	Phosphorylation	-	69.95	27251275
403 (in isoform 2)	Phosphorylation	-	54.52	24719451
429	Phosphorylation	LLPESTVSPQASTPI CCCCCCCCCCCCCCC	16.04	-
452	Phosphorylation	PGSLPIPSQPQFSHD CCCCCCCCCCCCCCC	56.03	17553757
464	Phosphorylation	SHDIFIPSPSLEEQS CCCEECCCCCHHHHC	23.46	-
482	Phosphorylation	KKDGDMHSSSLTVEC CCCCCCCCCEEEEEE	18.25	25159151
483	Phosphorylation	KDGDMHSSSLTVECS CCCCCCCCEEEEEEE	18.06	29255136
484	Phosphorylation	DGDMHSSSLTVECSK CCCCCCCEEEEEEEC	30.95	29255136
486	Phosphorylation	DMHSSSLTVECSKTS CCCCCEEEEEEECCC	19.06	29255136
489 (in isoform 2)	Phosphorylation	-	4.37	27251275
490	Phosphorylation	SSLTVECSKTSEIEP CEEEEEEECCCCCCC	26.01	20068231
492	Phosphorylation	LTVECSKTSEIEPKN EEEEEECCCCCCCCC	18.46	23927012
493	Phosphorylation	TVECSKTSEIEPKNS EEEEECCCCCCCCCC	40.07	23927012
500	Phosphorylation	SEIEPKNSPEDLGLS CCCCCCCCHHHHCCC	35.47	19664994
505 (in isoform 2)	Phosphorylation	-	26.07	24719451
507	Phosphorylation	SPEDLGLSLTGDSCK CHHHHCCCCCCCCEE	23.30	23927012
509	Phosphorylation	EDLGLSLTGDSCKLM HHHCCCCCCCCEEEE	35.25	30266825
512	Phosphorylation	GLSLTGDSCKLMLST CCCCCCCCEEEEECC	17.94	30266825
512 (in isoform 2)	Phosphorylation	-	17.94	24719451
514 (in isoform 2)	Phosphorylation	-	40.66	27251275
517 (in isoform 2)	Phosphorylation	-	7.97	27251275
518	Phosphorylation	DSCKLMLSTSEYSQS CCEEEEECCCCCCCC	18.87	30278072
519	Phosphorylation	SCKLMLSTSEYSQSP CEEEEECCCCCCCCC	22.93	30278072
520	Phosphorylation	CKLMLSTSEYSQSPK EEEEECCCCCCCCCC	31.03	23927012
522	Phosphorylation	LMLSTSEYSQSPKME EEECCCCCCCCCCCC	16.27	23927012
523	Phosphorylation	MLSTSEYSQSPKMES EECCCCCCCCCCCCC	21.82	29255136
523 (in isoform 2)	Phosphorylation	-	21.82	27251275
525	Phosphorylation	STSEYSQSPKMESLS CCCCCCCCCCCCCHH	22.13	19664994
527	Acetylation	SEYSQSPKMESLSSH CCCCCCCCCCCHHCC	61.62	25953088
527	Ubiquitination	SEYSQSPKMESLSSH CCCCCCCCCCCHHCC	61.62	2189047
527 (in isoform 1)	Ubiquitination	-	61.62	21890473
528 (in isoform 2)	Phosphorylation	-	4.86	24719451
530	Phosphorylation	SQSPKMESLSSHRID CCCCCCCCHHCCCCC	30.01	23927012
530 (in isoform 2)	Phosphorylation	-	30.01	21406692
532	Phosphorylation	SPKMESLSSHRIDED CCCCCCHHCCCCCCC	33.12	25159151
532 (in isoform 2)	Ubiquitination	-	33.12	21890473
533	Phosphorylation	PKMESLSSHRIDEDG CCCCCHHCCCCCCCC	23.29	23927012
535 (in isoform 2)	Phosphorylation	-	39.75	27251275
537 (in isoform 2)	Phosphorylation	-	48.14	21406692
538 (in isoform 2)	Phosphorylation	-	66.59	21406692
543	Phosphorylation	IDEDGENTQIEDTEP CCCCCCCCCCCCCCC	26.99	17525332
548	Phosphorylation	ENTQIEDTEPMSPVL CCCCCCCCCCCCCCC	29.24	17525332
548 (in isoform 2)	Phosphorylation	-	29.24	27251275
552	Phosphorylation	IEDTEPMSPVLNSKF CCCCCCCCCCCCCCC	23.67	29255136
553 (in isoform 2)	Phosphorylation	-	28.50	24719451
557	Phosphorylation	PMSPVLNSKFVPAEN CCCCCCCCCCCCCCC	24.26	23927012
557 (in isoform 2)	Phosphorylation	-	24.26	21406692
566	Phosphorylation	FVPAENDSILMNPAQ CCCCCCCCCCCCCCC	29.24	17525332
571 (in isoform 2)	Phosphorylation	-	19.82	27251275
580	Phosphorylation	QDGEVQLSQNDDKTK CCCCEEECCCCCCCC	15.17	29255136
585 (in isoform 2)	Phosphorylation	-	55.81	21406692
586	Phosphorylation	LSQNDDKTKGDDTDT ECCCCCCCCCCCCCC	47.45	22167270
591	Phosphorylation	DKTKGDDTDTRDDIS CCCCCCCCCCHHHHH	43.97	23401153
593	Phosphorylation	TKGDDTDTRDDISIL CCCCCCCCHHHHHHC	37.78	23401153
598	Phosphorylation	TDTRDDISILATGCK CCCHHHHHHCCCCCC	20.67	30266825
598 (in isoform 2)	Phosphorylation	-	20.67	27251275
602	Phosphorylation	DDISILATGCKGREE HHHHHCCCCCCCCCC	39.40	26552605
603 (in isoform 2)	Phosphorylation	-	12.92	27251275
620	Phosphorylation	EDVCIDLTCDSGSQA CEEEEEEEECCCCCC	15.54	27251275
623	Phosphorylation	CIDLTCDSGSQAVPS EEEEEECCCCCCCCC	42.35	30266825
625	Phosphorylation	DLTCDSGSQAVPSPA EEEECCCCCCCCCCC	20.93	17525332
625 (in isoform 2)	Phosphorylation	-	20.93	27251275
628 (in isoform 2)	Phosphorylation	-	3.60	27251275
630	Phosphorylation	SGSQAVPSPATRSEA CCCCCCCCCCCHHHH	22.14	30266825
633	Phosphorylation	QAVPSPATRSEALSS CCCCCCCCHHHHHHH	37.80	30266825
635	Phosphorylation	VPSPATRSEALSSVL CCCCCCHHHHHHHHC	23.90	26503892
635 (in isoform 2)	Phosphorylation	-	23.90	24719451
639	Phosphorylation	ATRSEALSSVLDQEE CCHHHHHHHHCCHHH	26.00	22167270
640	Phosphorylation	TRSEALSSVLDQEEA CHHHHHHHHCCHHHH	27.78	22167270
640 (in isoform 2)	Phosphorylation	-	27.78	24719451
644 (in isoform 2)	Phosphorylation	-	46.39	24719451
645 (in isoform 2)	Phosphorylation	-	47.60	24719451
659	O-linked_Glycosylation	EHHPEEGSSGSEVEE HHCCCCCCCCCCCCC	34.50	23301498
659	Phosphorylation	EHHPEEGSSGSEVEE HHCCCCCCCCCCCCC	34.50	26503892
660	Phosphorylation	HHPEEGSSGSEVEEI HCCCCCCCCCCCCCC	58.14	26503892
662	Phosphorylation	PEEGSSGSEVEEIPE CCCCCCCCCCCCCCC	40.18	26503892
664 (in isoform 2)	Phosphorylation	-	9.53	21406692
665 (in isoform 2)	Phosphorylation	-	46.27	21406692
667 (in isoform 2)	Phosphorylation	-	2.06	27251275
670	Phosphorylation	EVEEIPETPCESQGE CCCCCCCCCCCCCCH	28.08	25159151
674	Phosphorylation	IPETPCESQGEELKE CCCCCCCCCCHHHHH	50.64	25159151
675 (in isoform 2)	Phosphorylation	-	40.81	27251275
679 (in isoform 2)	Phosphorylation	-	8.02	21406692
680	Sumoylation	ESQGEELKEENMESV CCCCHHHHHHCCCCC	67.28	-
686	Phosphorylation	LKEENMESVPLHLSL HHHHCCCCCCEEEEC	20.47	25159151
692	Phosphorylation	ESVPLHLSLTETQSQ CCCCEEEECCHHHHC	23.62	25159151
694	Phosphorylation	VPLHLSLTETQSQGL CCEEEECCHHHHCCC	33.34	25159151
696	Phosphorylation	LHLSLTETQSQGLCL EEEECCHHHHCCCCC	28.43	25159151
697 (in isoform 2)	Phosphorylation	-	27.76	27251275
698	Phosphorylation	LSLTETQSQGLCLQK EECCHHHHCCCCCCC	33.37	46155915
713	Phosphorylation	EMPKKECSEAMEVET CCCHHHHHHCCCCEE	29.49	20873877
720	Phosphorylation	SEAMEVETSVISIDS HHCCCCEEEEEECCC	33.21	30266825
721	Phosphorylation	EAMEVETSVISIDSP HCCCCEEEEEECCCH	12.16	30266825
724	Phosphorylation	EVETSVISIDSPQKL CCEEEEEECCCHHHH	20.42	30266825
727	Phosphorylation	TSVISIDSPQKLAIL EEEEECCCHHHHHHH	27.79	30266825
729 (in isoform 2)	Phosphorylation	-	58.30	27251275
732 (in isoform 2)	Phosphorylation	-	13.82	24719451
750	Phosphorylation	QEAWEEATSEDSSVV HHHHHHHCCCCCCEE	35.61	25137130
751	Phosphorylation	EAWEEATSEDSSVVI HHHHHHCCCCCCEEE	46.59	25137130
754	Phosphorylation	EEATSEDSSVVIVDV HHHCCCCCCEEEEEC	22.45	30266825
755	Phosphorylation	EATSEDSSVVIVDVK HHCCCCCCEEEEECC	32.50	30266825
756 (in isoform 2)	Phosphorylation	-	3.84	27251275
765	Phosphorylation	IVDVKEPSPRVDVSC EEECCCCCCCCEEEE	26.82	30266825
770 (in isoform 2)	Phosphorylation	-	6.88	27251275
771	Phosphorylation	PSPRVDVSCEPLEGV CCCCCEEEECCCCCC	14.32	19664994
776 (in isoform 2)	Phosphorylation	-	72.42	24719451
782	Phosphorylation	LEGVEKCSDSQSWED CCCCCCCCCCCCHHH	51.90	25159151
784	Phosphorylation	GVEKCSDSQSWEDIA CCCCCCCCCCHHHHC	15.15	17525332
786	Phosphorylation	EKCSDSQSWEDIAPE CCCCCCCCHHHHCCC	36.06	25159151
787 (in isoform 2)	Phosphorylation	-	10.31	27251275
789 (in isoform 2)	Phosphorylation	-	35.77	27251275
791 (in isoform 2)	Phosphorylation	-	14.16	24719451
804	Phosphorylation	CAENRLDTKEEKSVE HHHCCCCCCHHHCCE	44.97	23663014
808	Ubiquitination	RLDTKEEKSVEYEGD CCCCCHHHCCEEECC	61.98	-
809	Phosphorylation	LDTKEEKSVEYEGDL CCCCHHHCCEEECCC	24.38	22167270
812	Phosphorylation	KEEKSVEYEGDLKSG CHHHCCEEECCCCCC	24.05	28796482
814 (in isoform 2)	Phosphorylation	-	44.65	24719451
817 (in isoform 2)	Phosphorylation	-	52.13	27642862
818	Phosphorylation	EYEGDLKSGTAETEP EEECCCCCCCCCCCC	48.99	29255136
820	Phosphorylation	EGDLKSGTAETEPVE ECCCCCCCCCCCCCC	28.54	29255136
823	Phosphorylation	LKSGTAETEPVEQDS CCCCCCCCCCCCCCC	43.03	29255136
830	Phosphorylation	TEPVEQDSSQPSLPL CCCCCCCCCCCCCCE	30.48	29255136
831	Phosphorylation	EPVEQDSSQPSLPLV CCCCCCCCCCCCCEE	55.17	29255136
834	Phosphorylation	EQDSSQPSLPLVRAD CCCCCCCCCCEEECC	34.67	29255136
835 (in isoform 2)	Phosphorylation	-	4.91	24719451
836 (in isoform 2)	Phosphorylation	-	32.90	27251275
839 (in isoform 2)	Phosphorylation	-	39.73	24719451
855	Phosphorylation	QELQQPQTQEKTSNS HHHCCCCCCCHHCCC	45.43	17525332
859	Phosphorylation	QPQTQEKTSNSLTED CCCCCCHHCCCCCHH	32.18	28176443
860	Phosphorylation	PQTQEKTSNSLTEDS CCCCCHHCCCCCHHH	35.17	28176443
860 (in isoform 2)	Phosphorylation	-	35.17	24719451
862	Phosphorylation	TQEKTSNSLTEDSKM CCCHHCCCCCHHHHH	36.11	23401153
864	O-linked_Glycosylation	EKTSNSLTEDSKMAN CHHCCCCCHHHHHHH	37.25	23301498
864	Phosphorylation	EKTSNSLTEDSKMAN CHHCCCCCHHHHHHH	37.25	26055452
867	Phosphorylation	SNSLTEDSKMANAKQ CCCCCHHHHHHHHHH	20.35	29396449
867 (in isoform 2)	Phosphorylation	-	20.35	24719451
868	Sumoylation	NSLTEDSKMANAKQL CCCCHHHHHHHHHHH	55.12	25114211
873	Ubiquitination	DSKMANAKQLSSDAE HHHHHHHHHHCCHHH	52.13	-
876	Phosphorylation	MANAKQLSSDAEAQK HHHHHHHCCHHHHHH	24.55	25159151
877	Phosphorylation	ANAKQLSSDAEAQKL HHHHHHCCHHHHHHH	49.81	25159151
878 (in isoform 2)	Ubiquitination	-	45.08	-
881 (in isoform 2)	Phosphorylation	-	17.33	24719451
888	Phosphorylation	AQKLGKPSAHASQSF HHHHCCCCHHHCHHH	35.85	20873877
892	Phosphorylation	GKPSAHASQSFCESS CCCCHHHCHHHHHCC	19.25	17525332
894	Phosphorylation	PSAHASQSFCESSSE CCHHHCHHHHHCCCC	29.39	25159151
897 (in isoform 2)	Phosphorylation	-	52.20	27251275
898	Phosphorylation	ASQSFCESSSETPFH HCHHHHHCCCCCCCE	40.10	25159151
899	Phosphorylation	SQSFCESSSETPFHF CHHHHHCCCCCCCEE	15.20	25159151
899 (in isoform 2)	Phosphorylation	-	15.20	24719451
900	Phosphorylation	QSFCESSSETPFHFT HHHHHCCCCCCCEEE	55.56	25159151
902	Phosphorylation	FCESSSETPFHFTLP HHHCCCCCCCEEECC	32.95	28450419
907	Phosphorylation	SETPFHFTLPKEGDI CCCCCEEECCCCCCC	33.31	30108239
919	Phosphorylation	GDIIPPLTGATPPLI CCCCCCCCCCCCCCC	30.46	29255136
922	Phosphorylation	IPPLTGATPPLIGHL CCCCCCCCCCCCCEE	27.12	29255136
927 (in isoform 2)	Phosphorylation	-	27.97	24719451
930	Sumoylation	PPLIGHLKLEPKRHS CCCCCEEECCCCCCC	45.17	-
930	Sumoylation	PPLIGHLKLEPKRHS CCCCCEEECCCCCCC	45.17	28112733
938	Phosphorylation	LEPKRHSTPIGISNY CCCCCCCCCCCCCCC	16.89	22254377
952	Phosphorylation	YPESTIATSDVMSES CCHHCCCCCHHCCHH	22.93	46155939
970	Phosphorylation	THDPILGSGKGDSGA CCCCCCCCCCCCCCC	33.61	20068231
975	Phosphorylation	LGSGKGDSGAAPDVD CCCCCCCCCCCCCCC	38.71	23401153
980 (in isoform 2)	Phosphorylation	-	52.32	21406692
984	Acetylation	AAPDVDDKLCLRMKL CCCCCCCHHHHEEEE	36.31	26822725
984	Sumoylation	AAPDVDDKLCLRMKL CCCCCCCHHHHEEEE	36.31	28112733
984	Ubiquitination	AAPDVDDKLCLRMKL CCCCCCCHHHHEEEE	36.31	-
993	Phosphorylation	CLRMKLVSPETEASE HHEEEECCCCCCCCH	27.70	30266825
996	Phosphorylation	MKLVSPETEASEESL EEECCCCCCCCHHHH	39.99	30266825
998 (in isoform 2)	Phosphorylation	-	29.66	27251275
999	Phosphorylation	VSPETEASEESLQFN CCCCCCCCHHHHCCC	35.35	23401153
1002	Phosphorylation	ETEASEESLQFNLEK CCCCCHHHHCCCCCC	24.34	23401153
1004 (in isoform 2)	Phosphorylation	-	34.17	27251275
1007 (in isoform 2)	Phosphorylation	-	10.65	24719451
1009	Acetylation	SLQFNLEKPATGERK HHCCCCCCCCCCCCC	43.02	26051181
1009	Ubiquitination	SLQFNLEKPATGERK HHCCCCCCCCCCCCC	43.02	-
1012	Phosphorylation	FNLEKPATGERKNGS CCCCCCCCCCCCCCC	48.37	28450419
1019	Phosphorylation	TGERKNGSTAVAESV CCCCCCCCEEHHHHH	23.68	22167270
1020	Phosphorylation	GERKNGSTAVAESVA CCCCCCCEEHHHHHC	26.92	22167270
1024 (in isoform 2)	Phosphorylation	-	38.86	21406692
1025	Phosphorylation	GSTAVAESVASPQKT CCEEHHHHHCCCHHH	17.16	23401153
1028	Phosphorylation	AVAESVASPQKTMSV EHHHHHCCCHHHHHH	26.21	19664994
1030 (in isoform 2)	Phosphorylation	-	51.89	21406692
1032	Phosphorylation	SVASPQKTMSVLSCI HHCCCHHHHHHHHHH	14.94	25159151
1033	Sulfoxidation	VASPQKTMSVLSCIC HCCCHHHHHHHHHHH	3.16	21406390
1033 (in isoform 2)	Phosphorylation	-	3.16	24719451
1034	Phosphorylation	ASPQKTMSVLSCICE CCCHHHHHHHHHHHH	25.74	28464451
1037	Phosphorylation	QKTMSVLSCICEARQ HHHHHHHHHHHHHHH	10.16	25159151
1042 (in isoform 2)	Phosphorylation	-	17.66	27251275
1050	Phosphorylation	RQENEARSEDPPTTP HHHHHHHCCCCCCCC	54.09	30266825
1055	Phosphorylation	ARSEDPPTTPIRGNL HHCCCCCCCCCCCCC	51.06	29255136
1055 (in isoform 2)	Phosphorylation	-	51.06	21406692
1056	Phosphorylation	RSEDPPTTPIRGNLL HCCCCCCCCCCCCCC	23.61	19664994
1060 (in isoform 2)	Phosphorylation	-	29.83	24719451
1061 (in isoform 2)	Phosphorylation	-	29.58	24719451
1067	Phosphorylation	GNLLHFPSSQGEEEK CCCCCCCCCCCHHHH	34.06	29255136
1068	Phosphorylation	NLLHFPSSQGEEEKE CCCCCCCCCCHHHHH	42.30	29255136
1072 (in isoform 2)	Phosphorylation	-	79.70	21406692
1073 (in isoform 2)	Phosphorylation	-	63.31	24719451
1082	Phosphorylation	EKLEGDHTIRQSQQP HHHCCCCHHCCCCCC	23.69	20363803
1086	Phosphorylation	GDHTIRQSQQPMKPI CCCHHCCCCCCCCCC	22.42	23927012
1094	O-linked_Glycosylation	QQPMKPISPVKDPVS CCCCCCCCCCCCCCC	31.97	23301498
1094	Phosphorylation	QQPMKPISPVKDPVS CCCCCCCCCCCCCCC	31.97	22167270
1099 (in isoform 2)	Phosphorylation	-	23.83	24719451
1101	Phosphorylation	SPVKDPVSPASQKMV CCCCCCCCHHHCCEE	21.82	29255136
1104	Phosphorylation	KDPVSPASQKMVIQG CCCCCHHHCCEEEEC	33.45	23927012
1106 (in isoform 2)	Phosphorylation	-	32.41	24719451
1109 (in isoform 2)	Phosphorylation	-	3.33	27251275
1113	Phosphorylation	KMVIQGPSSPQGEAM CEEEECCCCCCCCCH	62.57	22167270
1114	Phosphorylation	MVIQGPSSPQGEAMV EEEECCCCCCCCCHH	25.11	22167270
1118 (in isoform 2)	Phosphorylation	-	28.48	21406692
1119 (in isoform 2)	Phosphorylation	-	12.45	21406692
1122	Phosphorylation	PQGEAMVTDVLEDQK CCCCCHHHHHHHHHH	13.80	30266825
1127 (in isoform 2)	Phosphorylation	-	61.77	21406692
1133	Phosphorylation	EDQKEGRSTNKENPS HHHHCCCCCCCCCCC	47.38	26074081
1134	Phosphorylation	DQKEGRSTNKENPSK HHHCCCCCCCCCCCH	49.28	26074081
1141	Acetylation	TNKENPSKALIERPS CCCCCCCHHHHCCCC	48.76	26822725
1148	Phosphorylation	KALIERPSQNNIGIQ HHHHCCCCCCCCEEE	52.33	25159151
1153 (in isoform 2)	Phosphorylation	-	14.21	27251275
1156	Phosphorylation	QNNIGIQTMECSLRV CCCCEEEEEEEEEEC	17.02	21712546
1160	Phosphorylation	GIQTMECSLRVPETV EEEEEEEEEECCHHH	13.10	25159151
1162	Methylation	QTMECSLRVPETVSA EEEEEEEECCHHHHH	26.17	-
1166	Phosphorylation	CSLRVPETVSAATQT EEEECCHHHHHHHHH	17.43	21712546
1171	Phosphorylation	PETVSAATQTIKNVC CHHHHHHHHHHHHHH	26.43	17525332
1175	Methylation	SAATQTIKNVCEQGT HHHHHHHHHHHHHCC	46.87	-
1182	Phosphorylation	KNVCEQGTSTVDQNF HHHHHHCCCCCCCCC	22.40	25159151
1183	Phosphorylation	NVCEQGTSTVDQNFG HHHHHCCCCCCCCCC	33.00	21815630
1184	Phosphorylation	VCEQGTSTVDQNFGK HHHHCCCCCCCCCCC	28.12	25159151
1188 (in isoform 2)	Phosphorylation	-	43.08	27251275
1191	Acetylation	TVDQNFGKQDATVQT CCCCCCCCCCCEEEE	40.65	26051181
1195	Phosphorylation	NFGKQDATVQTERGS CCCCCCCEEEECCCC	22.80	28555341
1198	Phosphorylation	KQDATVQTERGSGEK CCCCEEEECCCCCCC	24.26	25627689
1202	Phosphorylation	TVQTERGSGEKPVSA EEEECCCCCCCCCCC	50.42	23927012
1208	Phosphorylation	GSGEKPVSAPGDDTE CCCCCCCCCCCCCCH	36.95	23927012
1213 (in isoform 2)	Phosphorylation	-	59.28	21406692
1214	Phosphorylation	VSAPGDDTESLHSQG CCCCCCCCHHHHHCC	32.01	17525332
1216	Phosphorylation	APGDDTESLHSQGEE CCCCCCHHHHHCCCH	33.21	23927012
1219	Phosphorylation	DDTESLHSQGEEEFD CCCHHHHHCCCHHCC	45.21	23927012
1219 (in isoform 2)	Phosphorylation	-	45.21	21406692
1221 (in isoform 2)	Phosphorylation	-	47.50	27251275
1224 (in isoform 2)	Phosphorylation	-	42.52	21406692
1258	Phosphorylation	TRVITDVYYVDGTEV HHHHEEEEEECCCEE	10.69	110749405
1259	Phosphorylation	RVITDVYYVDGTEVE HHHEEEEEECCCEEE	7.60	110749413
1263	Phosphorylation	DVYYVDGTEVERKVT EEEEECCCEEEEECC	32.18	110749421
1270	Phosphorylation	TEVERKVTEETEEPI CEEEEECCCCCCCCC	31.01	28450419
1273	Phosphorylation	ERKVTEETEEPIVEC EEECCCCCCCCCEEE	39.14	28450419
1285	Phosphorylation	VECQECETEVSPSQT EEEEECEEEECHHHC	54.03	23401153
1288	Phosphorylation	QECETEVSPSQTGGS EECEEEECHHHCCCC	16.77	25159151
1290	Phosphorylation	CETEVSPSQTGGSSG CEEEECHHHCCCCCC	32.63	17525332
1292	Phosphorylation	TEVSPSQTGGSSGDL EEECHHHCCCCCCCC	48.09	21955146
1295	Phosphorylation	SPSQTGGSSGDLGDI CHHHCCCCCCCCCCH	32.28	28450419
1295 (in isoform 2)	Phosphorylation	-	32.28	27251275
1296	Phosphorylation	PSQTGGSSGDLGDIS HHHCCCCCCCCCCHH	39.33	28450419
1303	Phosphorylation	SGDLGDISSFSSKAS CCCCCCHHHHHHHHH	30.03	28450419
1304	Phosphorylation	GDLGDISSFSSKASS CCCCCHHHHHHHHHH	29.49	28450419
1306	Phosphorylation	LGDISSFSSKASSLH CCCHHHHHHHHHHCE	32.64	28450419
1307	Phosphorylation	GDISSFSSKASSLHR CCHHHHHHHHHHCEE	30.17	28450419
1310	Phosphorylation	SSFSSKASSLHRTSS HHHHHHHHHCEECCC	36.85	29514088
1311	Phosphorylation	SFSSKASSLHRTSSG HHHHHHHHCEECCCC	32.81	29514088
1315	Phosphorylation	KASSLHRTSSGTSLS HHHHCEECCCCCCCE	19.25	25159151
1315 (in isoform 2)	Phosphorylation	-	19.25	21406692
1316	Phosphorylation	ASSLHRTSSGTSLSA HHHCEECCCCCCCEE	27.08	25159151
1317	Phosphorylation	SSLHRTSSGTSLSAM HHCEECCCCCCCEEE	45.54	25159151
1319	Phosphorylation	LHRTSSGTSLSAMHS CEECCCCCCCEEECC	28.57	25159151
1320	Phosphorylation	HRTSSGTSLSAMHSS EECCCCCCCEEECCC	24.69	25159151
1320 (in isoform 2)	Phosphorylation	-	24.69	21406692
1321 (in isoform 2)	Phosphorylation	-	3.67	21406692
1322	Phosphorylation	TSSGTSLSAMHSSGS CCCCCCCEEECCCCC	24.26	23927012
1322 (in isoform 2)	Phosphorylation	-	24.26	21406692
1324 (in isoform 2)	Phosphorylation	-	2.57	24719451
1325 (in isoform 2)	Phosphorylation	-	20.66	24719451
1326	Phosphorylation	TSLSAMHSSGSSGKG CCCEEECCCCCCCCC	24.26	23927012
1327	Phosphorylation	SLSAMHSSGSSGKGA CCEEECCCCCCCCCC	28.19	23927012
1327 (in isoform 2)	Phosphorylation	-	28.19	27251275
1329	Phosphorylation	SAMHSSGSSGKGAGP EEECCCCCCCCCCCC	37.55	23927012
1330	Phosphorylation	AMHSSGSSGKGAGPL EECCCCCCCCCCCCC	48.31	23927012
1332	Acetylation	HSSGSSGKGAGPLRG CCCCCCCCCCCCCCC	47.76	26051181
1332	Malonylation	HSSGSSGKGAGPLRG CCCCCCCCCCCCCCC	47.76	26320211
1340	Ubiquitination	GAGPLRGKTSGTEPA CCCCCCCCCCCCCCC	32.84	-
1341	Phosphorylation	AGPLRGKTSGTEPAD CCCCCCCCCCCCCCC	34.90	25159151
1342	Phosphorylation	GPLRGKTSGTEPADF CCCCCCCCCCCCCCC	47.40	25159151
1344	Phosphorylation	LRGKTSGTEPADFAL CCCCCCCCCCCCCCC	38.26	25159151
1347 (in isoform 2)	Phosphorylation	-	20.51	24719451
1349 (in isoform 2)	Phosphorylation	-	9.04	27251275
1353	Phosphorylation	PADFALPSSRGGPGK CCCCCCCCCCCCCCC	33.25	25159151
1354	Phosphorylation	ADFALPSSRGGPGKL CCCCCCCCCCCCCCC	32.76	21815630
1355	Methylation	DFALPSSRGGPGKLS CCCCCCCCCCCCCCC	59.43	-
1360	Acetylation	SSRGGPGKLSPRKGV CCCCCCCCCCCCCCC	49.26	25953088
1362	Phosphorylation	RGGPGKLSPRKGVSQ CCCCCCCCCCCCCCC	26.58	29255136
1365	Sumoylation	PGKLSPRKGVSQTGT CCCCCCCCCCCCCCC	68.03	28112733
1367 (in isoform 2)	Phosphorylation	-	4.26	24719451
1368	Phosphorylation	LSPRKGVSQTGTPVC CCCCCCCCCCCCCCC	30.60	23401153
1370	Phosphorylation	PRKGVSQTGTPVCEE CCCCCCCCCCCCCCC	35.20	30266825
1372	Phosphorylation	KGVSQTGTPVCEEDG CCCCCCCCCCCCCCC	18.88	30266825
1373 (in isoform 2)	Phosphorylation	-	30.06	27251275
1375	Glutathionylation	SQTGTPVCEEDGDAG CCCCCCCCCCCCCCC	5.09	22555962
1377 (in isoform 2)	Phosphorylation	-	63.27	24719451
1390	Acetylation	LGIRQGGKAPVTPRG CCCCCCCCCCCCCCC	57.23	7705865
1394	Phosphorylation	QGGKAPVTPRGRGRR CCCCCCCCCCCCCCC	13.25	46155927
1396	Methylation	GKAPVTPRGRGRRGR CCCCCCCCCCCCCCC	37.77	-
1398	Methylation	APVTPRGRGRRGRPP CCCCCCCCCCCCCCC	36.40	-
1400	Methylation	VTPRGRGRRGRPPSR CCCCCCCCCCCCCCC	36.20	-
1401	Methylation	TPRGRGRRGRPPSRT CCCCCCCCCCCCCCC	48.58	-
1403	Methylation	RGRGRRGRPPSRTTG CCCCCCCCCCCCCCC	37.84	-
1408	Phosphorylation	RGRPPSRTTGTRETA CCCCCCCCCCCCCCC	33.64	25954137
1409	Phosphorylation	GRPPSRTTGTRETAV CCCCCCCCCCCCCCC	35.13	25954137
1411	Phosphorylation	PPSRTTGTRETAVPG CCCCCCCCCCCCCCC	24.20	25954137
1414	Phosphorylation	RTTGTRETAVPGPLG CCCCCCCCCCCCCCC	29.66	23927012
1426	Phosphorylation	PLGIEDISPNLSPDD CCCCCCCCCCCCCCC	21.76	29255136
1430	Phosphorylation	EDISPNLSPDDKSFS CCCCCCCCCCCCCCC	32.68	19664994
1431 (in isoform 2)	Phosphorylation	-	57.92	24719451
1434	Sumoylation	PNLSPDDKSFSRVVP CCCCCCCCCCCCCCC	61.86	25114211
1435	Phosphorylation	NLSPDDKSFSRVVPR CCCCCCCCCCCCCCC	35.13	30278072
1435 (in isoform 2)	Phosphorylation	-	35.13	24719451
1437	Phosphorylation	SPDDKSFSRVVPRVP CCCCCCCCCCCCCCC	31.12	30278072
1440 (in isoform 2)	Phosphorylation	-	2.14	21406692
1446	Phosphorylation	VVPRVPDSTRRTDVG CCCCCCCCCCCCCCC	20.11	28555341
1447	Phosphorylation	VPRVPDSTRRTDVGA CCCCCCCCCCCCCCC	31.39	28555341
1450	Phosphorylation	VPDSTRRTDVGAGAL CCCCCCCCCCCCCCC	31.57	20068231
1460	Phosphorylation	GAGALRRSDSPEIPF CCCCCCCCCCCCCCC	35.69	29255136
1462	Phosphorylation	GALRRSDSPEIPFQA CCCCCCCCCCCCCCC	26.19	29255136
1465 (in isoform 2)	Phosphorylation	-	4.74	24719451
1467 (in isoform 2)	Phosphorylation	-	10.69	24719451
1474	Phosphorylation	FQAAAGPSDGLDASS CCCCCCCCCCCCCCC	43.31	30266825
1480	Phosphorylation	PSDGLDASSPGNSFV CCCCCCCCCCCCCCE	36.41	23927012
1481	Phosphorylation	SDGLDASSPGNSFVG CCCCCCCCCCCCCEE	38.25	26503892
1485	Phosphorylation	DASSPGNSFVGLRVV CCCCCCCCCEEEEEE	27.50	23927012
1486 (in isoform 2)	Phosphorylation	-	6.15	27251275
1494	Acetylation	VGLRVVAKWSSNGYF EEEEEEEEECCCCEE	35.68	26051181
1496	Phosphorylation	LRVVAKWSSNGYFYS EEEEEEECCCCEEEE	17.14	25159151
1500	Phosphorylation	AKWSSNGYFYSGKIT EEECCCCEEEECEEE	12.00	25884760
1505	Acetylation	NGYFYSGKITRDVGA CCEEEECEEEEECCC	34.66	26051181
1514	Acetylation	TRDVGAGKYKLLFDD EEECCCCEEEEECCC	38.38	26051181
1516	Ubiquitination	DVGAGKYKLLFDDGY ECCCCEEEEECCCCC	42.05	-
1523	Phosphorylation	KLLFDDGYECDVLGK EEECCCCCCCCCCCC	22.00	17360941
1545	Phosphorylation	IPLDTEVTALSEDEY CCCCCCEEECCCCCC	18.69	24719451
1548	Phosphorylation	DTEVTALSEDEYFSA CCCEEECCCCCCCCC	40.30	28192239
1550 (in isoform 2)	Phosphorylation	-	53.15	24719451
1552	Phosphorylation	TALSEDEYFSAGVVK EECCCCCCCCCCEEE	18.37	30834847
1553 (in isoform 2)	Phosphorylation	-	3.67	27251275
1554	Phosphorylation	LSEDEYFSAGVVKGH CCCCCCCCCCEEEEE	24.18	46155879
1559	Ubiquitination	YFSAGVVKGHRKESG CCCCCEEEEEECCCC	46.74	-
1563	Sumoylation	GVVKGHRKESGELYY CEEEEEECCCCCEEE	51.02	-
1563	Acetylation	GVVKGHRKESGELYY CEEEEEECCCCCEEE	51.02	26051181
1563	Sumoylation	GVVKGHRKESGELYY CEEEEEECCCCCEEE	51.02	25114211
1563	Ubiquitination	GVVKGHRKESGELYY CEEEEEECCCCCEEE	51.02	-
1569	Phosphorylation	RKESGELYYSIEKEG ECCCCCEEEEEEEHH	7.29	110749429
1571	Phosphorylation	ESGELYYSIEKEGQR CCCCEEEEEEEHHCH	15.66	21815630
1574	Acetylation	ELYYSIEKEGQRKWY CEEEEEEEHHCHHHH	66.53	26051181
1574	Ubiquitination	ELYYSIEKEGQRKWY CEEEEEEEHHCHHHH	66.53	-
1605	Phosphorylation	EQYGLGPYEAVTPLT HHHCCCCHHHCCCHH	18.09	21945579
1609	Phosphorylation	LGPYEAVTPLTKAAD CCCHHHCCCHHHHHC	21.45	21945579
1610 (in isoform 2)	Phosphorylation	-	31.28	27642862
1612	Phosphorylation	YEAVTPLTKAADISL HHHCCCHHHHHCCCH	21.60	21945579
1613	Ubiquitination	EAVTPLTKAADISLD HHCCCHHHHHCCCHH	49.62	-
1614 (in isoform 2)	Phosphorylation	-	12.72	24719451
1618	Phosphorylation	LTKAADISLDNLVEG HHHHHCCCHHHHHCC	30.16	19664994
1623 (in isoform 2)	Phosphorylation	-	13.13	24719451
1626	Acetylation	LDNLVEGKRKRRSNV HHHHHCCCCCCCCCC	41.04	25953088
1626	Methylation	LDNLVEGKRKRRSNV HHHHHCCCCCCCCCC	41.04	-
1626	Ubiquitination	LDNLVEGKRKRRSNV HHHHHCCCCCCCCCC	41.04	-
1631	Phosphorylation	EGKRKRRSNVSSPAT CCCCCCCCCCCCCCC	45.69	21955146
1634	Phosphorylation	RKRRSNVSSPATPTA CCCCCCCCCCCCCCC	34.55	30278072
1635	Phosphorylation	KRRSNVSSPATPTAS CCCCCCCCCCCCCCC	17.80	23401153
1636 (in isoform 2)	Phosphorylation	-	32.42	27251275
1638	Phosphorylation	SNVSSPATPTASSSS CCCCCCCCCCCCCCC	25.26	30278072
1640	Phosphorylation	VSSPATPTASSSSST CCCCCCCCCCCCCCC	34.51	11300805
1640 (in isoform 2)	Phosphorylation	-	34.51	24719451
1642	Phosphorylation	SPATPTASSSSSTTP CCCCCCCCCCCCCCC	32.98	23401153
1643	O-linked_Glycosylation	PATPTASSSSSTTPT CCCCCCCCCCCCCCC	31.60	23301498
1643	Phosphorylation	PATPTASSSSSTTPT CCCCCCCCCCCCCCC	31.60	23073121
1643 (in isoform 2)	Phosphorylation	-	31.60	24719451
1644	Phosphorylation	ATPTASSSSSTTPTR CCCCCCCCCCCCCCC	26.30	23401153
1645	Phosphorylation	TPTASSSSSTTPTRK CCCCCCCCCCCCCCC	33.38	30278072
1645 (in isoform 2)	Phosphorylation	-	33.38	21406692
1646	Phosphorylation	PTASSSSSTTPTRKI CCCCCCCCCCCCCCC	37.94	30278072
1647	Phosphorylation	TASSSSSTTPTRKIT CCCCCCCCCCCCCCC	38.45	28176443
1647 (in isoform 2)	Phosphorylation	-	38.45	27251275
1648	Phosphorylation	ASSSSSTTPTRKITE CCCCCCCCCCCCCCC	25.30	28176443
1649 (in isoform 2)	Phosphorylation	-	30.23	27251275
1650	Phosphorylation	SSSSTTPTRKITESP CCCCCCCCCCCCCCC	42.37	28176443
1650 (in isoform 2)	Phosphorylation	-	42.37	24719451
1651 (in isoform 2)	Phosphorylation	-	29.58	21406692
1654	Phosphorylation	TTPTRKITESPRASM CCCCCCCCCCCCHHH	33.18	22617229
1656	Phosphorylation	PTRKITESPRASMGV CCCCCCCCCCHHHCH	15.84	30266825
1660	Phosphorylation	ITESPRASMGVLSGK CCCCCCHHHCHHCCC	19.83	25159151
1661 (in isoform 2)	Phosphorylation	-	4.14	24719451
1665	Phosphorylation	RASMGVLSGKRKLIT CHHHCHHCCCCEECC	39.60	30266825
1665 (in isoform 2)	Phosphorylation	-	39.60	27251275
1667	Acetylation	SMGVLSGKRKLITSE HHCHHCCCCEECCCH	42.88	25953088
1670 (in isoform 2)	Phosphorylation	-	6.32	24719451
1672	Phosphorylation	SGKRKLITSEEERSP CCCCEECCCHHHCCC	40.29	22167270
1673	Phosphorylation	GKRKLITSEEERSPA CCCEECCCHHHCCCC	35.70	19664994
1678	Phosphorylation	ITSEEERSPAKRGRK CCCHHHCCCCCCCCC	32.27	29255136
1678 (in isoform 2)	Phosphorylation	-	32.27	21406692
1683 (in isoform 2)	Phosphorylation	-	40.43	24719451
1683 (in isoform 3)	Phosphorylation	-	40.43	29743597
1686	Phosphorylation	PAKRGRKSATVKPGA CCCCCCCCCEECCCC	28.01	63748543
1688	Phosphorylation	KRGRKSATVKPGAVG CCCCCCCEECCCCCC	35.83	28450419
1690	Acetylation	GRKSATVKPGAVGAG CCCCCEECCCCCCCC	33.12	26051181
1690	Ubiquitination	GRKSATVKPGAVGAG CCCCCEECCCCCCCC	33.12	-
1701	Phosphorylation	VGAGEFVSPCESGDN CCCCCCCCCCCCCCC	29.20	30278072
1704 (in isoform 3)	Phosphorylation	-	62.23	25954137
1705	Phosphorylation	EFVSPCESGDNTGEP CCCCCCCCCCCCCCC	59.15	30278072
1706 (in isoform 2)	Phosphorylation	-	15.19	24719451
1708 (in isoform 3)	Phosphorylation	-	54.21	25954137
1709	Phosphorylation	PCESGDNTGEPSALE CCCCCCCCCCCCHHH	47.89	25159151
1710 (in isoform 2)	Phosphorylation	-	51.58	24719451
1712 (in isoform 3)	Phosphorylation	-	26.67	25137130
1713	Phosphorylation	GDNTGEPSALEEQRG CCCCCCCCHHHHHCC	40.98	21712546
1749	Phosphorylation	SDKLASRSKLPDGPT CHHHHHCCCCCCCCC	35.73	23927012
1756	Phosphorylation	SKLPDGPTGSSEEEE CCCCCCCCCCCHHHH	56.05	23927012
1758	Phosphorylation	LPDGPTGSSEEEEEF CCCCCCCCCHHHHHH	36.73	23927012
1759	Phosphorylation	PDGPTGSSEEEEEFL CCCCCCCCHHHHHHH	50.82	23927012
1761 (in isoform 2)	Phosphorylation	-	73.06	24719451
1763 (in isoform 2)	Phosphorylation	-	58.28	21406692
1764 (in isoform 2)	Phosphorylation	-	59.83	24719451
1773	Ubiquitination	LEIPPFNKQYTESQL HCCCCCCCCCCHHHH	45.09	-
1778	Phosphorylation	FNKQYTESQLRAGAG CCCCCCHHHHHCCCC	27.07	16294045
1846	Phosphorylation	QLQNYRNYLLPAGYS HHHHHHHCCCCCCCC	10.70	28152594
1853	Phosphorylation	YLLPAGYSLEEQRIL CCCCCCCCHHHHHHH	28.52	28857561
1929	Phosphorylation	TDPSCPASVLKCAEA CCCCCCHHHHHHHHH	17.08	46155891
1960	Ubiquitination	VGERIGFKQHPKYKH HCCCCCCCCCCCCCC	42.35	-
1966	Ubiquitination	FKQHPKYKHDYVSH- CCCCCCCCCCCCCC-	35.81	-
1971	Phosphorylation	KYKHDYVSH------ CCCCCCCCC------	100.00	29496963
1976 (in isoform 2)	Phosphorylation	-		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
6	S	Phosphorylation	Kinase	ATM	Q13315	PhosphoELM
25	S	Phosphorylation	Kinase	ATM	Q13315	PSP
29	S	Phosphorylation	Kinase	ATM	Q13315	PSP
166	S	Phosphorylation	Kinase	ATR	Q13535	PSP
176	S	Phosphorylation	Kinase	ATR	Q13535	PSP
178	S	Phosphorylation	Kinase	ATR	Q13535	PSP
302	T	Phosphorylation	Kinase	ATR	Q13535	PSP
452	S	Phosphorylation	Kinase	ATR	Q13535	PSP
784	S	Phosphorylation	Kinase	ATM	Q13315	PhosphoELM
831	S	Phosphorylation	Kinase	ATR	Q13535	PSP
1219	S	Phosphorylation	Kinase	ATM	Q13315	PSP
1342	S	Phosphorylation	Kinase	AURKB	Q96GD4	GPS
1609	T	Phosphorylation	Kinase	CDK1	P06493	PSP
1618	S	Phosphorylation	Kinase	PLK1	P53350	PSP
1678	S	Phosphorylation	Kinase	CDK1	P06493	PSP
1678	S	Phosphorylation	Kinase	CHEK1	O14757	GPS
1778	S	Phosphorylation	Kinase	ATM	Q13315	PSP
-	K	Ubiquitination	E3 ubiquitin ligase	RAD18	Q9NS91	PMID:19228710

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
1609	T	Phosphorylation	Phosphorylation at Thr-1609 and Ser-1618 in the UDR motif blocks interaction with H2AK15ub.	18669648
1618	S	Phosphorylation	Phosphorylation at Thr-1609 and Ser-1618 in the UDR motif blocks interaction with H2AK15ub.	20068231

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TP53B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RFA2_HUMAN	RPA2	physical	15856006
BLM_HUMAN	BLM	physical	15364958
H2AX_HUMAN	H2AFX	physical	15364958
P53_HUMAN	TP53	physical	15364958
H2AX_HUMAN	H2AFX	physical	12447390
PAXI1_HUMAN	PAXIP1	physical	15456759
H2AX_HUMAN	H2AFX	physical	12697768
CHK1_HUMAN	CHEK1	physical	15364958
P53_HUMAN	TP53	physical	15611139
DCR1A_HUMAN	DCLRE1A	physical	12446782
RFA1_HUMAN	RPA1	physical	15856006
P53_MOUSE	Trp53	physical	16169070
E2F1_HUMAN	E2F1	physical	8896460
BRCA1_HUMAN	BRCA1	physical	17525332
P53_HUMAN	TP53	physical	8016121
RAD18_HUMAN	RAD18	physical	19228710
UBP28_HUMAN	USP28	physical	16901786
UBC9_HUMAN	UBE2I	physical	20016603
PIAS4_HUMAN	PIAS4	physical	20016603
RNF8_HUMAN	RNF8	physical	20016603
RN168_HUMAN	RNF168	physical	20016603
MDC1_HUMAN	MDC1	physical	18986980
HDAC4_HUMAN	HDAC4	physical	12668657
MDC1_HUMAN	MDC1	physical	17925396
H31_HUMAN	HIST1H3A	physical	17190600
RN168_HUMAN	RNF168	physical	21552324
BRCA1_HUMAN	BRCA1	physical	21552324
MDC1_HUMAN	MDC1	physical	12607005
H2AX_HUMAN	H2AFX	physical	21623170
CSN5_HUMAN	COPS5	physical	16187115
ACRO_HUMAN	ACR	physical	22990118
PCNT_HUMAN	PCNT	physical	22990118
PSMD8_HUMAN	PSMD8	physical	22990118
SDHB_HUMAN	SDHB	physical	22990118
JIP4_HUMAN	SPAG9	physical	22990118
GLTL5_HUMAN	GALNTL5	physical	22990118
AAMP_HUMAN	AAMP	physical	22990118
CAZA1_HUMAN	CAPZA1	physical	22990118
CAPZB_HUMAN	CAPZB	physical	22990118
CDC27_HUMAN	CDC27	physical	22990118
CUX1_HUMAN	CUX1	physical	22990118
CASP_HUMAN	CUX1	physical	22990118
ARI3A_HUMAN	ARID3A	physical	22990118
FAS_HUMAN	FASN	physical	22990118
FLNA_HUMAN	FLNA	physical	22990118
XRCC6_HUMAN	XRCC6	physical	22990118
IMA5_HUMAN	KPNA1	physical	22990118
IMB1_HUMAN	KPNB1	physical	22990118
IMA4_HUMAN	KPNA3	physical	22990118
MCM6_HUMAN	MCM6	physical	22990118
NUMA1_HUMAN	NUMA1	physical	22990118
PIMT_HUMAN	PCMT1	physical	22990118
MK01_HUMAN	MAPK1	physical	22990118
MK03_HUMAN	MAPK3	physical	22990118
PRS8_HUMAN	PSMC5	physical	22990118
PTN9_HUMAN	PTPN9	physical	22990118
REQU_HUMAN	DPF2	physical	22990118
RFC2_HUMAN	RFC2	physical	22990118
SAFB1_HUMAN	SAFB	physical	22990118
SRSF1_HUMAN	SRSF1	physical	22990118
SMRD1_HUMAN	SMARCD1	physical	22990118
LAP2A_HUMAN	TMPO	physical	22990118
LAP2B_HUMAN	TMPO	physical	22990118
P73_HUMAN	TP73	physical	22990118
TRPS1_HUMAN	TRPS1	physical	22990118
DNJC7_HUMAN	DNAJC7	physical	22990118
XRCC5_HUMAN	XRCC5	physical	22990118
1433Z_HUMAN	YWHAZ	physical	22990118
DEK_HUMAN	DEK	physical	22990118
HAT1_HUMAN	HAT1	physical	22990118
CDC23_HUMAN	CDC23	physical	22990118
CDC16_HUMAN	CDC16	physical	22990118
MTA2_HUMAN	MTA2	physical	22990118
APC10_HUMAN	ANAPC10	physical	22990118
RACK1_HUMAN	GNB2L1	physical	22990118
PUR6_HUMAN	PAICS	physical	22990118
ML12A_HUMAN	MYL12A	physical	22990118
NUDC_HUMAN	NUDC	physical	22990118
STRAP_HUMAN	STRAP	physical	22990118
CBX3_HUMAN	CBX3	physical	22990118
CLAP2_HUMAN	CLASP2	physical	22990118
RCOR1_HUMAN	RCOR1	physical	22990118
SUN2_HUMAN	SUN2	physical	22990118
DRS7B_HUMAN	DHRS7B	physical	22990118
CYBP_HUMAN	CACYBP	physical	22990118
ANC2_HUMAN	ANAPC2	physical	22990118
APC4_HUMAN	ANAPC4	physical	22990118
APC5_HUMAN	ANAPC5	physical	22990118
APC7_HUMAN	ANAPC7	physical	22990118
PELO_HUMAN	PELO	physical	22990118
UGGG1_HUMAN	UGGT1	physical	22990118
BEND3_HUMAN	BEND3	physical	22990118
APC1_HUMAN	ANAPC1	physical	22990118
ZBT10_HUMAN	ZBTB10	physical	22990118
APC16_HUMAN	ANAPC16	physical	22990118
FLCN_HUMAN	FLCN	physical	22990118
PLK1_HUMAN	PLK1	physical	20126263
VAC14_HUMAN	VAC14	physical	25416956
UB2L3_HUMAN	UBE2L3	physical	25422456
MSL1_HUMAN	MSL1	physical	19650074
RN168_HUMAN	RNF168	physical	25999347
PAXI1_HUMAN	PAXIP1	physical	26344197
RPAC1_HUMAN	POLR1C	physical	26344197
TCP4_HUMAN	SUB1	physical	26344197
PLK1_HUMAN	PLK1	physical	25607646
UBC_HUMAN	UBC	physical	25607646
TIF1B_HUMAN	TRIM28	physical	25905708
H2AX_HUMAN	H2AFX	physical	26734725
P53_HUMAN	TP53	physical	27546791
UBP28_HUMAN	USP28	physical	27546791
PR38A_HUMAN	PRPF38A	physical	27173435
BUB1_HUMAN	BUB1	physical	25963654
P53_HUMAN	TP53	physical	25651062

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-265; SER-294; SER-366;SER-380; SER-398; SER-500; TYR-522; SER-523; SER-525; THR-543;SER-552; SER-834; SER-1028; SER-1114; SER-1426; SER-1430; SER-1460;SER-1462; SER-1474 AND SER-1618, AND MASS SPECTROMETRY.
PubMed: 19690332

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-265; SER-294; SER-380;THR-382; THR-394; SER-395; SER-398; SER-500; SER-523; SER-525;SER-552; SER-580; SER-635; SER-640; SER-771; SER-831; SER-999;THR-1020; SER-1028; THR-1055; THR-1056; SER-1113; SER-1114; SER-1430;SER-1618; SER-1635; THR-1638; THR-1640; SER-1643; SER-1645; SER-1646;THR-1647; THR-1648; THR-1672; SER-1673; SER-1678; SER-1701 ANDSER-1705, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-222; SER-265; SER-395;SER-398; SER-500; SER-523; SER-525; SER-552; SER-771; SER-809;SER-831; THR-855; SER-876; SER-877; SER-1028; SER-1094; SER-1101;THR-1214; SER-1216; SER-1219; SER-1368; THR-1372; SER-1426; SER-1430;SER-1435; SER-1462; THR-1609; SER-1618; THR-1672; SER-1673; SER-1678;SER-1701 AND THR-1709, AND MASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-380 AND SER-1462, ANDMASS SPECTROMETRY.
PubMed: 18220336

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-525 AND SER-1028, ANDMASS SPECTROMETRY.
PubMed: 18187866

"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-771; SER-809; SER-876;SER-1362; SER-1618 AND SER-1678, AND MASS SPECTROMETRY.
PubMed: 19007248

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-105; THR-302; SER-523;THR-543; THR-548; SER-552; SER-566; SER-580; SER-625; SER-784;SER-831; THR-855; SER-892; SER-1068; SER-1104; THR-1171; THR-1214;SER-1216; SER-1219 AND SER-1290, AND MASS SPECTROMETRY.
PubMed: 17525332

"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry.";
Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.;
Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1316; SER-1317;SER-1320; SER-1362; SER-1631; SER-1634; THR-1638; THR-1647 ANDSER-1678, AND MASS SPECTROMETRY.
PubMed: 17287340

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-771; THR-1056; SER-1426AND SER-1430, AND MASS SPECTROMETRY.
PubMed: 16964243

"Characterisation of the sites of DNA damage-induced 53BP1phosphorylation catalysed by ATM and ATR.";
Jowsey P., Morrice N.A., Hastie C.J., McLauchlan H., Toth R.,Rouse J.;
DNA Repair 6:1536-1544(2007).
Cited for: PHOSPHORYLATION AT SER-176; SER-178; SER-294; THR-302; SER-380;SER-452; SER-523; SER-552; SER-831; SER-1028; SER-1086; SER-1114 ANDSER-1219, AND MUTAGENESIS OF 176-SER--SER-178.
PubMed: 17553757

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-294; SER-500; SER-580;SER-635; SER-639; SER-640; SER-659; SER-660; SER-662; THR-750;SER-751; SER-754; SER-755; SER-993; THR-996; SER-999; SER-1002;SER-1094; SER-1362; SER-1426; SER-1430; SER-1673; SER-1678; SER-1701AND SER-1705, AND MASS SPECTROMETRY.
PubMed: 17081983

"Quantitative phosphoproteome analysis using a dendrimer conjugationchemistry and tandem mass spectrometry.";
Tao W.A., Wollscheid B., O'Brien R., Eng J.K., Li X.-J.,Bodenmiller B., Watts J.D., Hood L., Aebersold R.;
Nat. Methods 2:591-598(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1634; SER-1635 ANDTHR-1638, AND MASS SPECTROMETRY.
PubMed: 16094384

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-294; SER-316; SER-380;SER-500; SER-525; SER-552; SER-782; SER-831; SER-1028; THR-1056 ANDSER-1114, AND MASS SPECTROMETRY.
PubMed: 15302935