CASP_HUMAN - dbPTM
CASP_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CASP_HUMAN
UniProt AC Q13948
Protein Name Protein CASP
Gene Name CUX1
Organism Homo sapiens (Human).
Sequence Length 678
Subcellular Localization Golgi apparatus membrane
Single-pass type IV membrane protein .
Protein Description May be involved in intra-Golgi retrograde transport..
Protein Sequence MAANVGSMFQYWKRFDLQQLQRELDATATVLANRQDESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQGEIDALSKRSKEAEAAFLNVYKRLIDVPDPVPALDLGQQLQLKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGRCAELQVRITEAVATATEQRELIARLEQDLSIIQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRERFRARNQELEAENRLAQHTLQALQSELDSLRADNIKLFEKIKFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLSLSPWDKATLSMGRLVLSNKMARTIGFFYTLFLHCLVFLVLYKLAWSESMERDCATFCAKKFADHLHKFHENDNGAAAGDLWQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
78UbiquitinationFQGEIDALSKRSKEA
HHHHHHHHHHHHHHH		5.7121890473
78UbiquitinationFQGEIDALSKRSKEA
HHHHHHHHHHHHHHH		5.7121890473
94UbiquitinationAAFLNVYKRLIDVPD
HHHHHHHHHHCCCCC		36.1221890473
1862-HydroxyisobutyrylationLQNDFAEKERKLQET
HHHHHHHHHHHHHHH		60.43-
201UbiquitinationQMSTTSKLEEAEHKV
HHHHHHHHHHHHHHH		7.8221890473
201UbiquitinationQMSTTSKLEEAEHKV
HHHHHHHHHHHHHHH		7.8221890473
217UbiquitinationSLQTALEKTRTELFD
HHHHHHHHHHHHHHC		44.1221890473
2262-HydroxyisobutyrylationRTELFDLKTKYDEET
HHHHHCCCCCCCHHH		44.83-
331PhosphorylationLTKLRENSASQISQL
HHHHHHCCHHHHHHH		25.25-
333PhosphorylationKLRENSASQISQLEQ
HHHHCCHHHHHHHHH		28.0617525332
383UbiquitinationEFAPSEGAGTQDAAK
CCCCCCCCCCCCCCC		17.5121890473
383UbiquitinationEFAPSEGAGTQDAAK
CCCCCCCCCCCCCCC		17.5121890473
390 (in isoform 9)Phosphorylation-52.43-
395 (in isoform 9)Phosphorylation-3.09-
397 (in isoform 9)Phosphorylation-8.45-
399UbiquitinationLEVLLLEKNRSLQSE
HHHHHHHCCCCCCCC		58.5921890473
402PhosphorylationLLLEKNRSLQSENAA
HHHHCCCCCCCCCHH		39.9020068231
411 (in isoform 9)Phosphorylation-26.0928555341
413 (in isoform 10)Phosphorylation-24.69-
418 (in isoform 10)Phosphorylation-29.22-
420 (in isoform 10)Phosphorylation-17.07-
427 (in isoform 2)Phosphorylation-19.70-
429PhosphorylationAELQVRITEAVATAT
HHHHHHHHHHHHHHH		13.82-
432 (in isoform 2)Phosphorylation-3.86-
434PhosphorylationRITEAVATATEQREL
HHHHHHHHHHHHHHH		27.75-
434 (in isoform 2)Phosphorylation-27.75-
434 (in isoform 10)Phosphorylation-27.7528555341
436PhosphorylationTEAVATATEQRELIA
HHHHHHHHHHHHHHH		28.44-
444 (in isoform 9)Phosphorylation-31.5924173317
448 (in isoform 2)Phosphorylation-32.7728555341
450PhosphorylationARLEQDLSIIQSIQR
HHHHHHHHHHHHCCC		26.4028555341
461 (in isoform 9)Phosphorylation-57.66-
464 (in isoform 9)Phosphorylation-24.80-
467 (in isoform 10)Phosphorylation-35.7324173317
468 (in isoform 9)Phosphorylation-9.43-
481 (in isoform 2)Phosphorylation-2.7024173317
483PhosphorylationKEATALFYGPAAPAS
HHHHHHHHCCCCCCC		24.0524173317
484 (in isoform 10)Phosphorylation-9.68-
487 (in isoform 10)Phosphorylation-11.88-
491 (in isoform 10)Phosphorylation-32.99-
498 (in isoform 2)Phosphorylation-8.74-
500PhosphorylationLPEGQVDSLLSIISS
CCCCCHHHHHHHHHH		32.14-
501 (in isoform 2)Phosphorylation-3.63-
503PhosphorylationGQVDSLLSIISSQRE
CCHHHHHHHHHHHHH		24.14-
505 (in isoform 2)Phosphorylation-2.66-
507PhosphorylationSLLSIISSQRERFRA
HHHHHHHHHHHHHHH		23.89-
517 (in isoform 9)Phosphorylation-51.6130108239
518 (in isoform 9)Phosphorylation-52.7227251275
523 (in isoform 9)Phosphorylation-51.8430108239
525 (in isoform 9)Phosphorylation-8.9627251275
528 (in isoform 9)Phosphorylation-23.9627251275
536 (in isoform 9)Phosphorylation-43.5725884760
540 (in isoform 10)Phosphorylation-5.3730108239
541 (in isoform 10)Phosphorylation-43.7927251275
544 (in isoform 9)Phosphorylation-32.1026657352
545 (in isoform 9)Phosphorylation-4.1725159151
546 (in isoform 10)Phosphorylation-54.0730108239
547 (in isoform 9)Phosphorylation-6.2430108239
548 (in isoform 10)Phosphorylation-8.3627251275
551 (in isoform 10)Phosphorylation-2.7627251275
554 (in isoform 2)Phosphorylation-2.5430108239
555 (in isoform 2)Phosphorylation-44.0127251275
556PhosphorylationEKIKFLQSYPGRGSG
HHHHHHHCCCCCCCC		35.1330108239
557PhosphorylationKIKFLQSYPGRGSGS
HHHHHHCCCCCCCCC		9.2027251275
559 (in isoform 10)Phosphorylation-38.0525884760
560 (in isoform 2)Phosphorylation-31.4430108239
562PhosphorylationQSYPGRGSGSDDTEL
HCCCCCCCCCCCCCH		33.4930108239
562 (in isoform 2)Phosphorylation-33.4927251275
564PhosphorylationYPGRGSGSDDTELRY
CCCCCCCCCCCCHHH		33.7327251275
565 (in isoform 2)Phosphorylation-71.0827251275
567 (in isoform 10)Phosphorylation-41.7426657352
567PhosphorylationRGSGSDDTELRYSSQ
CCCCCCCCCHHHCHH		41.7427251275
568 (in isoform 10)Phosphorylation-37.9425159151
570 (in isoform 10)Phosphorylation-24.0530108239
570MethylationGSDDTELRYSSQYEE
CCCCCCHHHCHHHHH		24.05-
573 (in isoform 2)Phosphorylation-28.0425884760
574 (in isoform 9)Phosphorylation-43.6521964256
575PhosphorylationELRYSSQYEERLDPF
CHHHCHHHHHHCCCC		23.0025884760
577UbiquitinationRYSSQYEERLDPFSS
HHCHHHHHHCCCCCC		54.3221890473
577UbiquitinationRYSSQYEERLDPFSS
HHCHHHHHHCCCCCC		54.3221890473
581 (in isoform 2)Phosphorylation-35.2926657352
582 (in isoform 2)Phosphorylation-10.7625159151
583PhosphorylationEERLDPFSSFSKRER
HHHCCCCCCCCHHHH		35.5426657352
584PhosphorylationERLDPFSSFSKRERQ
HHCCCCCCCCHHHHH		33.6425159151
584 (in isoform 2)Phosphorylation-33.6430108239
586UbiquitinationLDPFSSFSKRERQRK
CCCCCCCCHHHHHHH		32.5221890473
586UbiquitinationLDPFSSFSKRERQRK
CCCCCCCCHHHHHHH		32.5221890473
586PhosphorylationLDPFSSFSKRERQRK
CCCCCCCCHHHHHHH		32.5221712546
593UbiquitinationSKRERQRKYLSLSPW
CHHHHHHHHCCCCHH		42.0521890473
594PhosphorylationKRERQRKYLSLSPWD
HHHHHHHHCCCCHHH		12.0527642862
597 (in isoform 10)Phosphorylation-7.0521964256
602UbiquitinationLSLSPWDKATLSMGR
CCCCHHHHHHHHHHH		39.1321890473
611 (in isoform 2)Phosphorylation-5.4721964256
613PhosphorylationSMGRLVLSNKMARTI
HHHHHHHCHHHHHHH		27.2521964256
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CASP_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CASP_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CASP_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BIN1_HUMANBIN1physical
16169070
RNZ2_HUMANELAC2physical
16169070
RECQ5_HUMANRECQL5physical
16169070
CDK7_HUMANCDK7physical
11584018
CCNA1_HUMANCCNA1physical
11584018
SATB1_HUMANSATB1physical
10373541
TLE4_HUMANTLE4physical
19332113
EHMT2_HUMANEHMT2physical
15269344
Drug and Disease Associations
Kegg Disease
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CASP_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory