dbPTM

BLM_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BLM_HUMAN
UniProt AC	P54132
Protein Name	Bloom syndrome protein
Gene Name	BLM
Organism	Homo sapiens (Human).
Sequence Length	1417
Subcellular Localization	Nucleus . Together with SPIDR, is redistributed in discrete nuclear DNA damage-induced foci following hydroxyurea (HU) or camptothecin (CPT) treatment. Accumulated at sites of DNA damage in a RMI complex- and SPIDR-dependent manner.
Protein Description	ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction. [PubMed: 9388193]
Protein Sequence	MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVLRNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVCTTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRVSTAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDDGPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDFVPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSDASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFSATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASINDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	QEQLERHSARTLNNK HHHHHHHHHHHHHHH	26.18	25159151
20	Phosphorylation	LERHSARTLNNKLSL HHHHHHHHHHHHHCC	33.29	-
24	Sumoylation	SARTLNNKLSLSKPK HHHHHHHHHCCCCCC	38.08	-
24	Sumoylation	SARTLNNKLSLSKPK HHHHHHHHHCCCCCC	38.08	28112733
24	Ubiquitination	SARTLNNKLSLSKPK HHHHHHHHHCCCCCC	38.08	-
26	Phosphorylation	RTLNNKLSLSKPKFS HHHHHHHCCCCCCCC	32.00	25159151
28	Phosphorylation	LNNKLSLSKPKFSGF HHHHHCCCCCCCCCE	43.46	21712546
29	Acetylation	NNKLSLSKPKFSGFT HHHHCCCCCCCCCEE	58.48	25953088
31	Sumoylation	KLSLSKPKFSGFTFK HHCCCCCCCCCEEEE	56.76	-
31	Acetylation	KLSLSKPKFSGFTFK HHCCCCCCCCCEEEE	56.76	25953088
31	Sumoylation	KLSLSKPKFSGFTFK HHCCCCCCCCCEEEE	56.76	28112733
33	Phosphorylation	SLSKPKFSGFTFKKK CCCCCCCCCEEEEEE	38.84	25159151
36	Phosphorylation	KPKFSGFTFKKKTSS CCCCCCEEEEEECCC	37.76	23186163
38	Methylation	KFSGFTFKKKTSSDN CCCCEEEEEECCCCC	50.75	-
38	Sumoylation	KFSGFTFKKKTSSDN CCCCEEEEEECCCCC	50.75	28112733
39	Methylation	FSGFTFKKKTSSDNN CCCEEEEEECCCCCC	58.03	-
40	Sumoylation	SGFTFKKKTSSDNNV CCEEEEEECCCCCCE	54.98	-
40	Sumoylation	SGFTFKKKTSSDNNV CCEEEEEECCCCCCE	54.98	-
41	Phosphorylation	GFTFKKKTSSDNNVS CEEEEEECCCCCCEE	42.20	30177828
42	Phosphorylation	FTFKKKTSSDNNVSV EEEEEECCCCCCEEE	44.57	30177828
43	Phosphorylation	TFKKKTSSDNNVSVT EEEEECCCCCCEEEE	49.98	22199227
48	Phosphorylation	TSSDNNVSVTNVSVA CCCCCCEEEEEEEEE	25.91	25159151
50	Phosphorylation	SDNNVSVTNVSVAKT CCCCEEEEEEEEEEC	23.54	19691289
53	Phosphorylation	NVSVTNVSVAKTPVL CEEEEEEEEEECCCC	20.58	25159151
56	Sumoylation	VTNVSVAKTPVLRNK EEEEEEEECCCCCCC	51.73	-
56	Sumoylation	VTNVSVAKTPVLRNK EEEEEEEECCCCCCC	51.73	28112733
57	Phosphorylation	TNVSVAKTPVLRNKD EEEEEEECCCCCCCC	14.64	26055452
63	Sumoylation	KTPVLRNKDVNVTED ECCCCCCCCCCCCCC	57.53	28112733
68	Phosphorylation	RNKDVNVTEDFSFSE CCCCCCCCCCCCCCC	25.32	21712546
72	Phosphorylation	VNVTEDFSFSEPLPN CCCCCCCCCCCCCCC	39.94	30576142
74	Phosphorylation	VTEDFSFSEPLPNTT CCCCCCCCCCCCCCC	36.79	25159151
87	Sumoylation	TTNQQRVKDFFKNAP CCCHHHHHHHHHCCC	51.51	28112733
91	Sumoylation	QRVKDFFKNAPAGQE HHHHHHHHCCCCCCC	52.79	-
91	Sumoylation	QRVKDFFKNAPAGQE HHHHHHHHCCCCCCC	52.79	28112733
91	Ubiquitination	QRVKDFFKNAPAGQE HHHHHHHHCCCCCCC	52.79	-
99	Phosphorylation	NAPAGQETQRGGSKS CCCCCCCCCCCCCCC	18.71	16199871
104	Phosphorylation	QETQRGGSKSLLPDF CCCCCCCCCCCCHHH	23.15	21712546
105	Sumoylation	ETQRGGSKSLLPDFL CCCCCCCCCCCHHHH	48.69	-
105	Sumoylation	ETQRGGSKSLLPDFL CCCCCCCCCCCHHHH	48.69	28112733
105	Ubiquitination	ETQRGGSKSLLPDFL CCCCCCCCCCCHHHH	48.69	-
106	Phosphorylation	TQRGGSKSLLPDFLQ CCCCCCCCCCHHHHC	36.51	21712546
114	Phosphorylation	LLPDFLQTPKEVVCT CCHHHHCCCCEEEEE	38.18	29255136
116	Sumoylation	PDFLQTPKEVVCTTQ HHHHCCCCEEEEECC	67.54	28112733
121	Phosphorylation	TPKEVVCTTQNTPTV CCCEEEEECCCCCCC	21.58	24732914
122	Phosphorylation	PKEVVCTTQNTPTVK CCEEEEECCCCCCCC	18.07	29255136
125	Phosphorylation	VVCTTQNTPTVKKSR EEEECCCCCCCCCCH	15.54	29255136
127	Phosphorylation	CTTQNTPTVKKSRDT EECCCCCCCCCCHHH	42.81	29255136
129	Sumoylation	TQNTPTVKKSRDTAL CCCCCCCCCCHHHHH	47.73	-
129	Acetylation	TQNTPTVKKSRDTAL CCCCCCCCCCHHHHH	47.73	25953088
129	Sumoylation	TQNTPTVKKSRDTAL CCCCCCCCCCHHHHH	47.73	28112733
129	Ubiquitination	TQNTPTVKKSRDTAL CCCCCCCCCCHHHHH	47.73	-
131	Phosphorylation	NTPTVKKSRDTALKK CCCCCCCCHHHHHHH	29.66	21712546
142	Phosphorylation	ALKKLEFSSSPDSLS HHHHCCCCCCCCCCC	22.11	28176443
143	Phosphorylation	LKKLEFSSSPDSLST HHHCCCCCCCCCCCC	51.73	28176443
144	Phosphorylation	KKLEFSSSPDSLSTI HHCCCCCCCCCCCCC	31.37	28176443
147	Phosphorylation	EFSSSPDSLSTINDW CCCCCCCCCCCCCCC	27.83	28176443
149	Phosphorylation	SSSPDSLSTINDWDD CCCCCCCCCCCCCCC	31.06	28450419
150	Phosphorylation	SSPDSLSTINDWDDM CCCCCCCCCCCCCCC	29.15	28464451
162	Phosphorylation	DDMDDFDTSETSKSF CCCCCCCCCCCHHCC	28.58	28176443
163	Phosphorylation	DMDDFDTSETSKSFV CCCCCCCCCCHHCCC	40.50	28176443
165	Phosphorylation	DDFDTSETSKSFVTP CCCCCCCCHHCCCCC	41.02	28176443
166	Phosphorylation	DFDTSETSKSFVTPP CCCCCCCHHCCCCCC	23.42	28176443
167	Ubiquitination	FDTSETSKSFVTPPQ CCCCCCHHCCCCCCC	56.16	-
168	Phosphorylation	DTSETSKSFVTPPQS CCCCCHHCCCCCCCC	25.39	30266825
171	Phosphorylation	ETSKSFVTPPQSHFV CCHHCCCCCCCCCEE	27.52	30266825
175	Phosphorylation	SFVTPPQSHFVRVST CCCCCCCCCEEECCC	25.35	28450419
181	Phosphorylation	QSHFVRVSTAQKSKK CCCEEECCCCCCCCC	13.88	27282143
182	Phosphorylation	SHFVRVSTAQKSKKG CCEEECCCCCCCCCC	30.19	-
195	Sumoylation	KGKRNFFKAQLYTTN CCCCCEEEEEEEECC	30.96	-
195	Methylation	KGKRNFFKAQLYTTN CCCCCEEEEEEEECC	30.96	-
195	Sumoylation	KGKRNFFKAQLYTTN CCCCCEEEEEEEECC	30.96	28112733
199	Phosphorylation	NFFKAQLYTTNTVKT CEEEEEEEECCCCCC	10.23	-
201	Phosphorylation	FKAQLYTTNTVKTDL EEEEEEECCCCCCCC	18.48	28555341
205	Sumoylation	LYTTNTVKTDLPPPS EEECCCCCCCCCCCC	33.99	28112733
225	Ubiquitination	IDLTEEQKDDSEWLS CCCCHHHCCCCCHHC	67.78	-
259	Ubiquitination	AQESDSLKTHLEDER CHHCCHHHHHHHHCC	37.54	-
269	Phosphorylation	LEDERDNSEKKKNLE HHHCCCCHHHHHCHH	55.90	30576142
282	Phosphorylation	LEEAELHSTEKVPCI HHHHHHHCCCCCCCE	51.38	25159151
283	Phosphorylation	EEAELHSTEKVPCIE HHHHHHCCCCCCCEE	29.13	25849741
296	Phosphorylation	IEFDDDDYDTDFVPP EECCCCCCCCCCCCC	27.95	28102081
298	Phosphorylation	FDDDDYDTDFVPPSP CCCCCCCCCCCCCCH	25.71	29116813
304	Phosphorylation	DTDFVPPSPEEIISA CCCCCCCCHHHHHCC	38.58	25159151
312	Phosphorylation	PEEIISASSSSSKCL HHHHHCCCCCCHHHH	24.78	25852190
313	Phosphorylation	EEIISASSSSSKCLS HHHHCCCCCCHHHHH	33.68	25852190
314	Phosphorylation	EIISASSSSSKCLST HHHCCCCCCHHHHHH	35.81	25852190
315	Phosphorylation	IISASSSSSKCLSTL HHCCCCCCHHHHHHH	35.45	25852190
316	Phosphorylation	ISASSSSSKCLSTLK HCCCCCCHHHHHHHH	29.36	25852190
317	Sumoylation	SASSSSSKCLSTLKD CCCCCCHHHHHHHHC	40.94	-
317	Sumoylation	SASSSSSKCLSTLKD CCCCCCHHHHHHHHC	40.94	-
323	Ubiquitination	SKCLSTLKDLDTSDR HHHHHHHHCCCCCCC	57.23	-
327	Phosphorylation	STLKDLDTSDRKEDV HHHHCCCCCCCHHHH	39.56	25159151
328	Phosphorylation	TLKDLDTSDRKEDVL HHHCCCCCCCHHHHH	34.78	23401153
331	Sumoylation	DLDTSDRKEDVLSTS CCCCCCCHHHHHHHC	64.36	-
331	Sumoylation	DLDTSDRKEDVLSTS CCCCCCCHHHHHHHC	64.36	28112733
331	Ubiquitination	DLDTSDRKEDVLSTS CCCCCCCHHHHHHHC	64.36	-
336	Phosphorylation	DRKEDVLSTSKDLLS CCHHHHHHHCHHHHC	30.40	25159151
337	Phosphorylation	RKEDVLSTSKDLLSK CHHHHHHHCHHHHCC	35.32	25159151
338	Phosphorylation	KEDVLSTSKDLLSKP HHHHHHHCHHHHCCH	22.31	25159151
339	Ubiquitination	EDVLSTSKDLLSKPE HHHHHHCHHHHCCHH	53.11	-
343	Phosphorylation	STSKDLLSKPEKMSM HHCHHHHCCHHHCCH	54.16	27259358
344	Sumoylation	TSKDLLSKPEKMSMQ HCHHHHCCHHHCCHH	58.11	-
344	Sumoylation	TSKDLLSKPEKMSMQ HCHHHHCCHHHCCHH	58.11	28112733
344	Ubiquitination	TSKDLLSKPEKMSMQ HCHHHHCCHHHCCHH	58.11	-
347	Sumoylation	DLLSKPEKMSMQELN HHHCCHHHCCHHHHC	44.81	-
347	Sumoylation	DLLSKPEKMSMQELN HHHCCHHHCCHHHHC	44.81	28112733
349	Phosphorylation	LSKPEKMSMQELNPE HCCHHHCCHHHHCCC	28.51	25159151
357	Phosphorylation	MQELNPETSTDCDAR HHHHCCCCCCCHHHH	37.88	25159151
358	Phosphorylation	QELNPETSTDCDARQ HHHCCCCCCCHHHHH	22.16	25159151
359	Phosphorylation	ELNPETSTDCDARQI HHCCCCCCCHHHHHH	48.33	25159151
367	Phosphorylation	DCDARQISLQQQLIH CHHHHHHHHHHHHHH	16.28	25159151
390	Acetylation	IDTIPDDKLKLLDCG HHHCCCCCCCHHHHC	55.70	26051181
390	Ubiquitination	IDTIPDDKLKLLDCG HHHCCCCCCCHHHHC	55.70	-
392	Sumoylation	TIPDDKLKLLDCGNE HCCCCCCCHHHHCHH	53.39	-
392	Sumoylation	TIPDDKLKLLDCGNE HCCCCCCCHHHHCHH	53.39	-
392	Ubiquitination	TIPDDKLKLLDCGNE HCCCCCCCHHHHCHH	53.39	-
409	Sumoylation	QQRNIRRKLLTEVDF HHHHHHHHHHHHCCC	37.69	-
409	Sumoylation	QQRNIRRKLLTEVDF HHHHHHHHHHHHCCC	37.69	-
409	Ubiquitination	QQRNIRRKLLTEVDF HHHHHHHHHHHHCCC	37.69	-
412	Phosphorylation	NIRRKLLTEVDFNKS HHHHHHHHHCCCCHH	44.38	28450419
418	Sumoylation	LTEVDFNKSDASLLG HHHCCCCHHHHHHHH	50.10	-
418	Sumoylation	LTEVDFNKSDASLLG HHHCCCCHHHHHHHH	50.10	-
418	Ubiquitination	LTEVDFNKSDASLLG HHHCCCCHHHHHHHH	50.10	-
419	Phosphorylation	TEVDFNKSDASLLGS HHCCCCHHHHHHHHH	39.24	25159151
422	Phosphorylation	DFNKSDASLLGSLWR CCCHHHHHHHHHHHC	29.17	25159151
426	Phosphorylation	SDASLLGSLWRYRPD HHHHHHHHHHCCCCC	25.40	25159151
430	Phosphorylation	LLGSLWRYRPDSLDG HHHHHHCCCCCCCCC	18.21	29396449
434	Phosphorylation	LWRYRPDSLDGPMEG HHCCCCCCCCCCCCC	30.92	25159151
443	Phosphorylation	DGPMEGDSCPTGNSM CCCCCCCCCCCCCCC	32.62	21712546
449	Phosphorylation	DSCPTGNSMKELNFS CCCCCCCCCCCCCCC	32.35	25159151
451	Sumoylation	CPTGNSMKELNFSHL CCCCCCCCCCCCCCC	59.89	28112733
456	Phosphorylation	SMKELNFSHLPSNSV CCCCCCCCCCCCCCC	24.04	24732914
460	Phosphorylation	LNFSHLPSNSVSPGD CCCCCCCCCCCCCCC	48.36	24732914
462	Phosphorylation	FSHLPSNSVSPGDCL CCCCCCCCCCCCCEE	28.45	25159151
464	Phosphorylation	HLPSNSVSPGDCLLT CCCCCCCCCCCEEEE	24.00	25159151
471	Phosphorylation	SPGDCLLTTTLGKTG CCCCEEEECCCCCCC	12.56	24732914
472	Phosphorylation	PGDCLLTTTLGKTGF CCCEEEECCCCCCCC	21.72	24732914
473	Phosphorylation	GDCLLTTTLGKTGFS CCEEEECCCCCCCCC	28.42	24732914
476	Acetylation	LLTTTLGKTGFSATR EEECCCCCCCCCCHH	48.89	26051181
476	Sumoylation	LLTTTLGKTGFSATR EEECCCCCCCCCCHH	48.89	28112733
476	Ubiquitination	LLTTTLGKTGFSATR EEECCCCCCCCCCHH	48.89	-
480	Phosphorylation	TLGKTGFSATRKNLF CCCCCCCCCHHCCHH	30.03	21815630
482	Phosphorylation	GKTGFSATRKNLFER CCCCCCCHHCCHHCC	40.76	29396449
484	Sumoylation	TGFSATRKNLFERPL CCCCCHHCCHHCCCC	54.36	-
484	Sumoylation	TGFSATRKNLFERPL CCCCCHHCCHHCCCC	54.36	28112733
484	Ubiquitination	TGFSATRKNLFERPL CCCCCHHCCHHCCCC	54.36	-
494	Phosphorylation	FERPLFNTHLQKSFV HCCCCCCHHHHHHHH	19.34	28555341
498	Sumoylation	LFNTHLQKSFVSSNW CCCHHHHHHHHCCCC	52.82	-
498	Sumoylation	LFNTHLQKSFVSSNW CCCHHHHHHHHCCCC	52.82	28112733
499	Phosphorylation	FNTHLQKSFVSSNWA CCHHHHHHHHCCCCC	20.23	25159151
502	Phosphorylation	HLQKSFVSSNWAETP HHHHHHHCCCCCCCC	18.88	29396449
503	Phosphorylation	LQKSFVSSNWAETPR HHHHHHCCCCCCCCC	30.96	26074081
508	Phosphorylation	VSSNWAETPRLGKKN HCCCCCCCCCCCCCC	13.13	25159151
513	Sumoylation	AETPRLGKKNESSYF CCCCCCCCCCCCCCC	57.95	28112733
514	Sumoylation	ETPRLGKKNESSYFP CCCCCCCCCCCCCCC	65.24	-
514	Sumoylation	ETPRLGKKNESSYFP CCCCCCCCCCCCCCC	65.24	28112733
514	Ubiquitination	ETPRLGKKNESSYFP CCCCCCCCCCCCCCC	65.24	-
517	Phosphorylation	RLGKKNESSYFPGNV CCCCCCCCCCCCCCC	39.47	28555341
518	Phosphorylation	LGKKNESSYFPGNVL CCCCCCCCCCCCCCE	25.31	28555341
519	Phosphorylation	GKKNESSYFPGNVLT CCCCCCCCCCCCCEE	24.07	28555341
526	Phosphorylation	YFPGNVLTSTAVKDQ CCCCCCEEHHEEECC	21.54	25627689
527	Phosphorylation	FPGNVLTSTAVKDQN CCCCCEEHHEEECCC	15.37	25627689
528	Phosphorylation	PGNVLTSTAVKDQNK CCCCEEHHEEECCCC	30.18	25159151
531	Sumoylation	VLTSTAVKDQNKHTA CEEHHEEECCCCCCC	51.65	28112733
531	Ubiquitination	VLTSTAVKDQNKHTA CEEHHEEECCCCCCC	51.65	-
535	Sumoylation	TAVKDQNKHTASIND HEEECCCCCCCCHHH	36.38	28112733
535	Ubiquitination	TAVKDQNKHTASIND HEEECCCCCCCCHHH	36.38	-
537	Phosphorylation	VKDQNKHTASINDLE EECCCCCCCCHHHHH	24.57	26055452
539	Phosphorylation	DQNKHTASINDLERE CCCCCCCCHHHHHHH	24.07	25159151
550	Phosphorylation	LERETQPSYDIDNFD HHHHCCCCCCCCCCC	26.14	18669648
551	Phosphorylation	ERETQPSYDIDNFDI HHHCCCCCCCCCCCC	24.49	18669648
578	Ubiquitination	MHNLAASKSSTAAYQ HHHHHHCCCCCCCCC	43.64	-
579	Phosphorylation	HNLAASKSSTAAYQP HHHHHCCCCCCCCCC	30.35	25159151
580	Phosphorylation	NLAASKSSTAAYQPI HHHHCCCCCCCCCCC	26.29	25159151
581	Phosphorylation	LAASKSSTAAYQPIK HHHCCCCCCCCCCCC	23.54	22199227
588	Sumoylation	TAAYQPIKEGRPIKS CCCCCCCCCCCCCCC	61.88	-
588	Sumoylation	TAAYQPIKEGRPIKS CCCCCCCCCCCCCCC	61.88	28112733
588	Ubiquitination	TAAYQPIKEGRPIKS CCCCCCCCCCCCCCC	61.88	-
594	Sumoylation	IKEGRPIKSVSERLS CCCCCCCCCHHHHHH	47.70	-
594	Sumoylation	IKEGRPIKSVSERLS CCCCCCCCCHHHHHH	47.70	28112733
594	Ubiquitination	IKEGRPIKSVSERLS CCCCCCCCCHHHHHH	47.70	-
597	Phosphorylation	GRPIKSVSERLSSAK CCCCCCHHHHHHCCC	24.88	29396449
601	Phosphorylation	KSVSERLSSAKTDCL CCHHHHHHCCCCCCE	34.18	19691289
602	Phosphorylation	SVSERLSSAKTDCLP CHHHHHHCCCCCCEE	38.07	19691289
604	Sumoylation	SERLSSAKTDCLPVS HHHHHCCCCCCEECC	47.01	28112733
604	Ubiquitination	SERLSSAKTDCLPVS HHHHHCCCCCCEECC	47.01	-
629	Ubiquitination	SIQNYTDKSAQNLAS HHHHCCCHHHHHHHH	39.63	-
646	Phosphorylation	LKHERFQSLSFPHTK CCHHHHHHCCCCCHH	24.22	25159151
652	Phosphorylation	QSLSFPHTKEMMKIF HHCCCCCHHHHHHHH	29.01	28509920
653	Ubiquitination	SLSFPHTKEMMKIFH HCCCCCHHHHHHHHH	40.35	-
657	Acetylation	PHTKEMMKIFHKKFG CCHHHHHHHHHHHHC	40.69	19816819
661	Acetylation	EMMKIFHKKFGLHNF HHHHHHHHHHCCCCC	38.76	19816827
662	Sumoylation	MMKIFHKKFGLHNFR HHHHHHHHHCCCCCC	35.77	-
662	Acetylation	MMKIFHKKFGLHNFR HHHHHHHHHCCCCCC	35.77	19816835
662	Sumoylation	MMKIFHKKFGLHNFR HHHHHHHHHCCCCCC	35.77	-
662	Ubiquitination	MMKIFHKKFGLHNFR HHHHHHHHHCCCCCC	35.77	-
695	Sumoylation	LMPTGGGKSLCYQLP EEECCCCCCHHHCCC	43.46	-
695	Sumoylation	LMPTGGGKSLCYQLP EEECCCCCCHHHCCC	43.46	11500040
696	Phosphorylation	MPTGGGKSLCYQLPA EECCCCCCHHHCCCC	27.26	20068231
699	Phosphorylation	GGGKSLCYQLPACVS CCCCCHHHCCCCCCC	20.55	20068231
706	Phosphorylation	YQLPACVSPGVTVVI HCCCCCCCCCEEEEE	18.80	20068231
714	Phosphorylation	PGVTVVISPLRSLIV CCEEEEECCCHHHHH	13.28	16880735
729	Phosphorylation	DQVQKLTSLDIPATY HHHHHHHHCCCCCEE	34.18	28787133
736	Phosphorylation	SLDIPATYLTGDKTD HCCCCCEEECCCCCC	12.36	-
741	Ubiquitination	ATYLTGDKTDSEATN CEEECCCCCCHHHHH	56.42	-
742	Phosphorylation	TYLTGDKTDSEATNI EEECCCCCCHHHHHH	49.88	30576142
750	Phosphorylation	DSEATNIYLQLSKKD CHHHHHHHHHHCCCC	7.17	30576142
755	Acetylation	NIYLQLSKKDPIIKL HHHHHHCCCCCCEEE	70.55	19608861
755	Ubiquitination	NIYLQLSKKDPIIKL HHHHHHCCCCCCEEE	70.55	19608861
764	Phosphorylation	DPIIKLLYVTPEKIC CCCEEEEEECHHHHH	16.83	27251275
766	Phosphorylation	IIKLLYVTPEKICAS CEEEEEECHHHHHHC	16.51	30266825
769	Ubiquitination	LLYVTPEKICASNRL EEEECHHHHHHCCCH	44.27	-
773	Phosphorylation	TPEKICASNRLISTL CHHHHHHCCCHHHHH	20.33	-
820	Sumoylation	RMNMLRQKFPSVPVM HHHHHHHHCCCCCEE	53.46	-
820	Sumoylation	RMNMLRQKFPSVPVM HHHHHHHHCCCCCEE	53.46	-
820	Ubiquitination	RMNMLRQKFPSVPVM HHHHHHHHCCCCCEE	53.46	-
823	Phosphorylation	MLRQKFPSVPVMALT HHHHHCCCCCEEEEE	42.03	26503514
830	Phosphorylation	SVPVMALTATANPRV CCCEEEEECCCCHHH	16.66	-
832	Phosphorylation	PVMALTATANPRVQK CEEEEECCCCHHHHH	23.02	-
839	Sumoylation	TANPRVQKDILTQLK CCCHHHHHHHHHHHH	43.83	-
839	Sumoylation	TANPRVQKDILTQLK CCCHHHHHHHHHHHH	43.83	-
839	Ubiquitination	TANPRVQKDILTQLK CCCHHHHHHHHHHHH	43.83	-
863	Acetylation	SFNRHNLKYYVLPKK EECCCCCEEEECCCC	39.59	19608861
863	Ubiquitination	SFNRHNLKYYVLPKK EECCCCCEEEECCCC	39.59	19608861
873	Sumoylation	VLPKKPKKVAFDCLE ECCCCCCCCHHHHHH	47.53	-
873	Sumoylation	VLPKKPKKVAFDCLE ECCCCCCCCHHHHHH	47.53	-
873	Ubiquitination	VLPKKPKKVAFDCLE ECCCCCCCCHHHHHH	47.53	-
888	Phosphorylation	WIRKHHPYDSGIIYC HHHHHCCCCCCCEEE	20.55	26552605
890	Phosphorylation	RKHHPYDSGIIYCLS HHHCCCCCCCEEECC	26.50	26552605
894	Phosphorylation	PYDSGIIYCLSRREC CCCCCCEEECCHHCC	5.85	26552605
897	Phosphorylation	SGIIYCLSRRECDTM CCCEEECCHHCCCCH	26.23	26552605
903	Phosphorylation	LSRRECDTMADTLQR CCHHCCCCHHHHHHH	26.39	-
907	Phosphorylation	ECDTMADTLQRDGLA CCCCHHHHHHHHHHH	18.43	-
968	Acetylation	VIHASLPKSVEGYYQ EEEECCCCCCCEEHH	72.87	26051181
1057	Ubiquitination	FNPDFCKKHPDVSCD CCHHHHHHCCCCCCC	62.64	-
1082	Sumoylation	RDVTDDVKSIVRFVQ CCCCHHHHHHHHHHH	41.27	-
1082	Sumoylation	RDVTDDVKSIVRFVQ CCCCHHHHHHHHHHH	41.27	-
1082	Ubiquitination	RDVTDDVKSIVRFVQ CCCCHHHHHHHHHHH	41.27	-
1083	Phosphorylation	DVTDDVKSIVRFVQE CCCHHHHHHHHHHHH	26.60	20860994
1125	Sumoylation	FLGSKSAKIQSGIFG HHCCCCCEEECCCCC	48.66	-
1125	Acetylation	FLGSKSAKIQSGIFG HHCCCCCEEECCCCC	48.66	25953088
1125	Sumoylation	FLGSKSAKIQSGIFG HHCCCCCEEECCCCC	48.66	28112733
1125	Ubiquitination	FLGSKSAKIQSGIFG HHCCCCCEEECCCCC	48.66	-
1128	Phosphorylation	SKSAKIQSGIFGKGS CCCCEEECCCCCCCC	37.01	29523821
1133	Acetylation	IQSGIFGKGSAYSRH EECCCCCCCCCCCHH	38.65	26051181
1133	Ubiquitination	IQSGIFGKGSAYSRH EECCCCCCCCCCCHH	38.65	-
1135	Phosphorylation	SGIFGKGSAYSRHNA CCCCCCCCCCCHHCH	27.76	29523821
1137	Phosphorylation	IFGKGSAYSRHNAER CCCCCCCCCHHCHHH	14.13	29523821
1138	Phosphorylation	FGKGSAYSRHNAERL CCCCCCCCHHCHHHH	27.12	29523821
1195	Phosphorylation	DFMETENSSSVKKQK EEEECCCCCCHHHHH	20.12	25159151
1196	Phosphorylation	FMETENSSSVKKQKA EEECCCCCCHHHHHH	51.21	21815630
1197	Phosphorylation	METENSSSVKKQKAL EECCCCCCHHHHHHH	37.46	21815630
1199	Sumoylation	TENSSSVKKQKALVA CCCCCCHHHHHHHHH	51.97	-
1199	Sumoylation	TENSSSVKKQKALVA CCCCCCHHHHHHHHH	51.97	28112733
1199	Ubiquitination	TENSSSVKKQKALVA CCCCCCHHHHHHHHH	51.97	-
1200	Ubiquitination	ENSSSVKKQKALVAK CCCCCHHHHHHHHHH	55.67	-
1207	Sumoylation	KQKALVAKVSQREEM HHHHHHHHHHHHHHH	34.63	28112733
1207	Ubiquitination	KQKALVAKVSQREEM HHHHHHHHHHHHHHH	34.63	-
1217	Ubiquitination	QREEMVKKCLGELTE HHHHHHHHHHHHHHH	24.23	-
1237	Phosphorylation	GKVFGVHYFNIFNTV HHHHCEEEEECCCCC	8.91	25219547
1243	Phosphorylation	HYFNIFNTVTLKKLA EEEECCCCCCHHHHH	12.24	25219547
1245	Phosphorylation	FNIFNTVTLKKLAES EECCCCCCHHHHHHH	30.71	25219547
1252	Phosphorylation	TLKKLAESLSSDPEV CHHHHHHHHCCCCCC	28.13	22210691
1254	Phosphorylation	KKLAESLSSDPEVLL HHHHHHHCCCCCCEE	41.81	22210691
1267	Phosphorylation	LLQIDGVTEDKLEKY EEEECCCCHHHHHHH	43.95	22210691
1273	Sumoylation	VTEDKLEKYGAEVIS CCHHHHHHHCHHHHH	60.46	-
1273	Sumoylation	VTEDKLEKYGAEVIS CCHHHHHHHCHHHHH	60.46	-
1273	Ubiquitination	VTEDKLEKYGAEVIS CCHHHHHHHCHHHHH	60.46	-
1280	Phosphorylation	KYGAEVISVLQKYSE HHCHHHHHHHHHHHC	23.19	25159151
1285	Phosphorylation	VISVLQKYSEWTSPA HHHHHHHHHCCCCCC	10.00	26074081
1286	Phosphorylation	ISVLQKYSEWTSPAE HHHHHHHHCCCCCCC	33.42	26074081
1289	Phosphorylation	LQKYSEWTSPAEDSS HHHHHCCCCCCCCCC	22.30	26074081
1290	Phosphorylation	QKYSEWTSPAEDSSP HHHHCCCCCCCCCCC	24.16	25159151
1295	Phosphorylation	WTSPAEDSSPGISLS CCCCCCCCCCCEECC	29.91	23401153
1296	Phosphorylation	TSPAEDSSPGISLSS CCCCCCCCCCEECCC	39.19	25159151
1300	Phosphorylation	EDSSPGISLSSSRGP CCCCCCEECCCCCCC	28.28	25262027
1302	Phosphorylation	SSPGISLSSSRGPGR CCCCEECCCCCCCCC	21.34	29978859
1303	Phosphorylation	SPGISLSSSRGPGRS CCCEECCCCCCCCCH	29.37	25159151
1304	Phosphorylation	PGISLSSSRGPGRSA CCEECCCCCCCCCHH	37.57	25159151
1310	Phosphorylation	SSRGPGRSAAEELDE CCCCCCCHHHHHHCC	37.43	30266825
1325	Phosphorylation	EIPVSSHYFASKTRN CCCCCHHHHHCCCCC	11.64	27642862
1329	Acetylation	SSHYFASKTRNERKR CHHHHHCCCCCHHHH	48.34	25953088
1329	Sumoylation	SSHYFASKTRNERKR CHHHHHCCCCCHHHH	48.34	28112733
1329	Ubiquitination	SSHYFASKTRNERKR CHHHHHCCCCCHHHH	48.34	-
1372	Sumoylation	RKISSKTKSSSIIGS HHCCCCCCCCCEECC	52.67	-
1372	Sumoylation	RKISSKTKSSSIIGS HHCCCCCCCCCEECC	52.67	28112733
1372	Ubiquitination	RKISSKTKSSSIIGS HHCCCCCCCCCEECC	52.67	-
1374	Phosphorylation	ISSKTKSSSIIGSSS CCCCCCCCCEECCCC	27.41	20860994
1375	Phosphorylation	SSKTKSSSIIGSSSA CCCCCCCCEECCCCC	25.89	28985074
1379	Phosphorylation	KSSSIIGSSSASHTS CCCCEECCCCCCCCC	15.65	20860994
1380	Phosphorylation	SSSIIGSSSASHTSQ CCCEECCCCCCCCCC	25.39	20860994
1381	Phosphorylation	SSIIGSSSASHTSQA CCEECCCCCCCCCCC	35.17	25159151
1383	Phosphorylation	IIGSSSASHTSQATS EECCCCCCCCCCCCC	29.28	21712546
1390	Phosphorylation	SHTSQATSGANSKLG CCCCCCCCCCCCCCC	38.63	20860994
1394	Phosphorylation	QATSGANSKLGIMAP CCCCCCCCCCCCCCC	28.82	20860994
1395	Sumoylation	ATSGANSKLGIMAPP CCCCCCCCCCCCCCC	51.01	28112733
1403	Acetylation	LGIMAPPKPINRPFL CCCCCCCCCCCCCCC	58.43	26051181
1411	Acetylation	PINRPFLKPSYAFS- CCCCCCCCCCCCCC-	32.09	19608861
1417	Phosphorylation	LKPSYAFS------- CCCCCCCC-------	31.01	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
99	T	Phosphorylation	Kinase	ATR	Q13535	PSP
99	T	Phosphorylation	Kinase	ATM	Q13315	PSP
122	T	Phosphorylation	Kinase	ATM	Q13315	PSP
122	T	Phosphorylation	Kinase	ATR	Q13535	PSP
144	S	Phosphorylation	Kinase	TTK	P33981	PSP
171	T	Phosphorylation	Kinase	GSK3B	P49841	PSP
175	S	Phosphorylation	Kinase	CDK2	P24941	PSP
182	T	Phosphorylation	Kinase	CHEK1	O14757	GPS
182	T	Phosphorylation	Kinase	CHEK2	O96017	GPS
338	S	Phosphorylation	Kinase	NEK11	Q8NG66	PSP
502	S	Phosphorylation	Kinase	CHK1	O14757	PSP
539	S	Phosphorylation	Kinase	CHEK1	O14757	GPS
646	S	Phosphorylation	Kinase	CHEK1	O14757	GPS
714	S	Phosphorylation	Kinase	CDK1	P06493	PSP
766	T	Phosphorylation	Kinase	CDK1	P06493	PSP
1290	S	Phosphorylation	Kinase	TTK	P33981	PSP
1296	S	Phosphorylation	Kinase	TTK	P33981	PSP
-	K	Ubiquitination	E3 ubiquitin ligase	RNF8	O76064	PMID:23708797
-	K	Ubiquitination	E3 ubiquitin ligase	TRIM49	P0CI25	PMID:23708797
-	K	Ubiquitination	E3 ubiquitin ligase	MIB1	Q86YT6	PMID:24239288

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
259	K	ubiquitylation		-
Poly-ubiquitinated by TRIM25 at Lys-259.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BLM_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TOP3A_HUMAN	TOP3A	physical	10734115
H2AX_HUMAN	H2AFX	physical	15364958
P53_HUMAN	TP53	physical	15364958
TP53B_HUMAN	TP53BP1	physical	15364958
FEN1_HUMAN	FEN1	physical	14688284
MLH1_HUMAN	MLH1	physical	11325959
CAF1A_HUMAN	CHAF1A	physical	15143166
P53_HUMAN	TP53	physical	11399766
P53_HUMAN	TP53	physical	11781842
XRCC2_HUMAN	XRCC2	physical	12975363
ATM_HUMAN	ATM	physical	12034743
RAD51_HUMAN	RAD51	physical	11278509
RFA1_HUMAN	RPA1	physical	10825162
TERF2_HUMAN	TERF2	physical	12181313
WRN_HUMAN	WRN	physical	11919194
MLH1_HUMAN	MLH1	physical	11470874
RFC1_HUMAN	RFC1	physical	10783165
RFA1_HUMAN	RPA1	physical	12181313
TOP3A_HUMAN	TOP3A	physical	10825162
P53_HUMAN	TP53	physical	12080066
TOP3A_HUMAN	TOP3A	physical	11406610
MLH1_HUMAN	MLH1	physical	11691925
EXO1_HUMAN	EXO1	physical	18971343
UBC9_HUMAN	UBE2I	physical	15829507
SYN1_HUMAN	SYN1	physical	15829507
MCRS1_HUMAN	MCRS1	physical	15829507
PSMD3_HUMAN	PSMD3	physical	15829507
FANCJ_HUMAN	BRIP1	physical	21240188
ATR_HUMAN	ATR	physical	14729972
FACD2_HUMAN	FANCD2	physical	15257300
FANCA_HUMAN	FANCA	physical	12724401
TOP3A_HUMAN	TOP3A	physical	12724401
MLH1_HUMAN	MLH1	physical	12724401
RFA1_HUMAN	RPA1	physical	12724401
RFA2_HUMAN	RPA2	physical	12724401
RFA3_HUMAN	RPA3	physical	12724401
MSH2_HUMAN	MSH2	physical	15064730
MSH6_HUMAN	MSH6	physical	15064730
ATRX_HUMAN	ATRX	physical	19671661
RAD51_HUMAN	RAD51	physical	19671661
TEP1_HUMAN	TEP1	physical	19329795
BLM_HUMAN	BLM	physical	19329795
HS90A_HUMAN	HSP90AA1	physical	19329795
TOP2A_HUMAN	TOP2A	physical	19329795
SF3B2_HUMAN	SF3B2	physical	19329795
RAD51_HUMAN	RAD51	physical	18562274
TERF2_HUMAN	TERF2	physical	15229185
TERF1_HUMAN	TERF1	physical	15229185
UIMC1_HUMAN	UIMC1	physical	23708797
BLM_HUMAN	BLM	physical	24239288
TOP3A_HUMAN	TOP3A	physical	24239288
TOPB1_HUMAN	TOPBP1	physical	24239288
RMI1_HUMAN	RMI1	physical	24239288
RFA1_HUMAN	RPA1	physical	24239288
PARP1_HUMAN	PARP1	physical	24239288
MIB1_HUMAN	MIB1	physical	24239288
P53_HUMAN	TP53	physical	24239288
PWP1_HUMAN	PWP1	physical	24239288
FAN1_HUMAN	FAN1	physical	25135477
FACD2_HUMAN	FANCD2	physical	25135477
RFA1_HUMAN	RPA1	physical	25135477
RAD50_HUMAN	RAD50	physical	25084169
AQR_HUMAN	AQR	genetic	24104479
TERA_HUMAN	VCP	genetic	24104479
MMS22_HUMAN	MMS22L	genetic	24104479
ELK4_HUMAN	ELK4	genetic	24104479
RS14_HUMAN	RPS14	genetic	24104479
ICK_HUMAN	ICK	genetic	24104479
XIAP_HUMAN	XIAP	genetic	24104479
U520_HUMAN	SNRNP200	genetic	24104479
PO3F3_HUMAN	POU3F3	genetic	24104479
SPT5H_HUMAN	SUPT5H	genetic	24104479
RS27A_HUMAN	RPS27A	genetic	24104479
ARP5_HUMAN	ACTR5	genetic	24104479
RL37_HUMAN	RPL37	genetic	24104479
RD23B_HUMAN	RAD23B	genetic	24104479
TRI15_HUMAN	TRIM15	genetic	24104479
TRIM8_HUMAN	TRIM8	genetic	24104479
RAD51_HUMAN	RAD51	genetic	24104479
TREX2_HUMAN	TREX2	genetic	24104479
RL14_HUMAN	RPL14	genetic	24104479
RREB1_HUMAN	RREB1	genetic	24104479
RL7_HUMAN	RPL7	genetic	24104479
AL3B1_HUMAN	ALDH3B1	genetic	24104479
RS19_HUMAN	RPS19	genetic	24104479
MO4L2_HUMAN	MORF4L2	genetic	24104479
H2A1_HUMAN	HIST1H2AI	genetic	24104479
NDUAD_HUMAN	NDUFA13	genetic	24104479
KLF16_HUMAN	KLF16	genetic	24104479
CSK2B_HUMAN	CSNK2B	genetic	24104479
SYCM_HUMAN	CARS2	genetic	24104479
ALDR_HUMAN	AKR1B1	genetic	24104479
RAMP1_HUMAN	RAMP1	genetic	24104479
PSMD1_HUMAN	PSMD1	genetic	24104479
HES5_HUMAN	HES5	genetic	24104479
RL23A_HUMAN	RPL23A	genetic	24104479
RMP_HUMAN	URI1	genetic	24104479
CEBPD_HUMAN	CEBPD	genetic	24104479
CASP8_HUMAN	CASP8	physical	26496610
TOP3A_HUMAN	TOP3A	physical	26496610
GANP_HUMAN	MCM3AP	physical	26496610
HPS5_HUMAN	HPS5	physical	26496610
CORO7_HUMAN	CORO7	physical	26496610
RMI1_HUMAN	RMI1	physical	26496610
F192A_HUMAN	FAM192A	physical	26496610
APBB1_HUMAN	APBB1	physical	23572515
FANCJ_HUMAN	BRIP1	physical	24895130
AIPL1_HUMAN	AIPL1	physical	27173435
PDE5A_HUMAN	PDE5A	physical	27173435
NEK4_HUMAN	NEK4	physical	27173435
MYC_HUMAN	MYC	physical	23750012
JUN_HUMAN	JUN	physical	23750012
FBXW7_HUMAN	FBXW7	physical	23750012

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
210900	Bloom syndrome (BLM)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BLM_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-863 AND LYS-1411, AND MASSSPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-499, AND MASSSPECTROMETRY.	19690332 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-48; SER-53; THR-57;THR-114; SER-358; SER-419; SER-422; SER-1295; SER-1296; SER-1303 ANDSER-1310, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-48; SER-282; SER-480 ANDSER-579, AND MASS SPECTROMETRY.	19007248 [Abstract]
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-480, AND MASSSPECTROMETRY.	17924679 [Abstract]
"Phosphoproteome analysis of the human mitotic spindle."; Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.; Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-419 AND SER-422, ANDMASS SPECTROMETRY.	16565220 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-499 AND THR-508, ANDMASS SPECTROMETRY.	16964243 [Abstract]
"Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1296, AND MASSSPECTROMETRY.	15302935 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-125, AND MASSSPECTROMETRY.	19413330 [Abstract]

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