TRI15_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TRI15_HUMAN
• UniProt AC: Q9C019
• Protein Name: Tripartite motif-containing protein 15
• Gene Name: TRIM15
• Organism: Homo sapiens (Human).
• Sequence Length: 465
• Protein Sequence: MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTLKG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MPATPSLKVVHEL --CCCCCCCEEEECC	36.15	24114839
249	Phosphorylation	QSRCEMKTFVSPEAI HHHCEEEEECCHHHC	28.14	23312004
252	Phosphorylation	CEMKTFVSPEAISPD CEEEEECCHHHCCHH	16.90	23312004
257	Phosphorylation	FVSPEAISPDLVKKI ECCHHHCCHHHHHHH	21.29	23312004
324	Phosphorylation	RYTRQKKSLPDSPLR HHHCCCCCCCCCCCC	52.77	23684312
328	Phosphorylation	QKKSLPDSPLRFDGL CCCCCCCCCCCCCCC	24.72	23684312
441	Phosphorylation	QEPIFTFTASFSGKV CCCEEEEEEEECCCE	20.52	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TRI15_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TRI15_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TRI15_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRI15_HUMAN	TRIM15	physical	20211142
TRIM8_HUMAN	TRIM8	physical	22493164
F151B_HUMAN	FAM151B	physical	25416956
PAXI_HUMAN	PXN	physical	25015296
TRI15_HUMAN	TRIM15	physical	25450970
COR1B_HUMAN	CORO1B	physical	25450970
SRC8_HUMAN	CTTN	physical	25450970
FBLI1_HUMAN	FBLIM1	physical	25450970
VASP_HUMAN	VASP	physical	25450970
AKT1_HUMAN	AKT1	physical	25450970
SRC_HUMAN	SRC	physical	25450970
CRK_HUMAN	CRK	physical	25450970
NCK2_HUMAN	NCK2	physical	25450970
KEAP1_HUMAN	KEAP1	physical	25450970
MOES_HUMAN	MSN	physical	25450970
NEXN_HUMAN	NEXN	physical	25450970
PROF1_HUMAN	PFN1	physical	25450970
APRIO_HUMAN	PRNP	physical	25450970
PRIO_HUMAN	PRNP	physical	25450970
FAK1_HUMAN	PTK2	physical	25450970
ROCK1_HUMAN	ROCK1	physical	25450970
SHC1_HUMAN	SHC1	physical	25450970
KSYK_HUMAN	SYK	physical	25450970
VINC_HUMAN	VCL	physical	25450970
VIME_HUMAN	VIM	physical	25450970
ACTB_HUMAN	ACTB	physical	25450970
COF1_HUMAN	CFL1	physical	25450970
FERM2_HUMAN	FERMT2	physical	25450970
URP2_HUMAN	FERMT3	physical	25450970
GAB1_HUMAN	GAB1	physical	25450970

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.